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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
TLYGLMAEFDDAEALLAAAEKTRDAGYKQFEAYTPMPIHGLDEAVGYRGTRLPWVIFGAGLLGASGMFALQTWINLVEYP
LNIGGRPLFSWPAFIPATFEGMVLLSAFAAVFGMIAACGLPRPYHPVFNAPNFERASVDRFFLCIEAADPKFELKQTRQF
LESLGPLAVSTVDN

The query sequence (length=174) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6loe:D 174 174 1.0000 1.0000 1.0000 1.02e-127
2 8k9e:D 175 173 0.5230 0.5200 0.5260 6.63e-59 8k9f:D, 8x2j:D
3 7jqh:A 313 53 0.1264 0.0703 0.4151 0.011 7jqi:A, 7jqj:A, 6ovl:A, 6oxn:A, 6p35:A
4 3kbo:A 312 102 0.1782 0.0994 0.3039 0.50 3kbo:B, 3kbo:C, 3kbo:D
5 7p6l:B 458 57 0.0977 0.0371 0.2982 5.0 7p6l:A, 7p6l:C, 7p6l:D
6 3w9z:A 290 43 0.0747 0.0448 0.3023 7.4
7 4bf9:A 318 43 0.0747 0.0409 0.3023 7.6 4bfa:A, 4bfa:B, 4yco:A, 4yco:B, 4yco:C, 4ycp:A
8 7ne2:D 292 60 0.0920 0.0548 0.2667 8.3 7ne2:A, 7ne2:B, 7ne2:C

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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