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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
TIEYQVKDMSLASLGRKRIEMAEKEMPGLMACRAKYGEEKPLNGVRITGSLHMTVETAVLIETLKAIGGNIRWCSCNIFS
TQDDAAAAIAAANTPVFAWKGETLVEYWECTWKAIRFGPYQGPQLIVDDGGDATLLIHRGFQAEKEPSILDEDGGVEELR
IVNNLLKRILKEEPGFFSKIVPDIKGVSEETTTGVHRLYAMQKQGTLLFPAINVNDSVTKSKFDNIYGCRHSLLDGLNRA
TDVMLAGKECVICGFGDVGKGCAEALKGQGARVIVTEIDPINALQACMAGYTVKTVEDCLATADIYVTATGNKDIITLDH
MKKMKDMAIICNIGHFDNEIDVLGLKTCEGVKEINIKPQVDQFLFPDGHSIILLAQGRLVNLGCATGHPAFVMSASFTNQ
TLAQISLWKDKYEIGVYTLPKVLDEEVARLHLEKLGAKLTKLTTSQADYIGVNANGPYKADHYRY

The query sequence (length=465) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5v96:A 467 465 1.0000 0.9957 1.0000 0.0 5v96:B, 5v96:C, 5v96:D
2 6uk3:A 475 464 0.7333 0.7179 0.7349 0.0 6uk3:C, 6uk3:B, 6uk3:D
3 3ond:B 488 473 0.6753 0.6434 0.6638 0.0 3ond:A, 3one:A, 3one:B, 3onf:A, 3onf:B
4 5m5k:C 471 468 0.6430 0.6348 0.6389 0.0 6exi:A, 6exi:B, 6exi:C, 6exi:D, 4lvc:A, 4lvc:B, 4lvc:C, 4lvc:D, 5m5k:A, 5m5k:B, 5m5k:D, 5m65:A, 5m65:B, 5m66:A, 5m66:B, 5m66:C, 5m66:D, 5m67:A, 5m67:B, 5m67:C, 5m67:D
5 3ce6:A 486 483 0.6151 0.5885 0.5921 0.0 3ce6:B, 3ce6:C, 3ce6:D, 3dhy:A, 3dhy:B, 3dhy:C, 3dhy:D, 2ziz:A, 2ziz:B, 2ziz:C, 2ziz:D, 2zj0:A, 2zj0:B, 2zj0:C, 2zj0:D, 2zj1:A, 2zj1:B, 2zj1:C, 2zj1:D
6 3n58:B 461 462 0.6129 0.6182 0.6169 0.0 3n58:A, 3n58:C, 3n58:D
7 3d64:A 462 465 0.5957 0.5996 0.5957 0.0 3d64:B, 3glq:A, 3glq:B
8 1v8b:A 476 473 0.5720 0.5588 0.5624 0.0 1v8b:B, 1v8b:C, 1v8b:D
9 5jpi:A 496 493 0.5892 0.5524 0.5558 0.0 5hm8:A, 5hm8:B, 5hm8:C, 5hm8:D, 5hm8:E, 5hm8:F, 5hm8:G, 5hm8:H, 5jpi:B, 5jpi:C, 5jpi:D, 5jxw:A, 5jxw:B, 5jxw:C, 5jxw:D, 5t8k:A, 5t8k:C, 5t8k:B, 5t8k:D, 5tj9:A, 5tj9:B, 5tj9:C, 5tj9:D, 5tls:A, 5tls:B, 5tls:C, 5tls:D, 5utu:A, 5utu:B, 5utu:C, 5utu:D, 5utu:E, 5utu:F, 5utu:G, 5utu:H
10 3h9u:C 435 471 0.5677 0.6069 0.5605 2.07e-177 3h9u:A, 3h9u:B, 3h9u:D
11 1a7a:A 431 467 0.5763 0.6218 0.5739 7.95e-177 1a7a:B, 5axa:A, 5axa:C, 5axb:A, 5axb:C, 5axc:A, 5axc:C, 5axd:A, 5axd:C, 1b3r:A, 1b3r:B, 1b3r:C, 1b3r:D, 8cod:A, 8cod:B, 1d4f:A, 1d4f:B, 1d4f:C, 1d4f:D, 2h5l:A, 2h5l:B, 2h5l:C, 2h5l:D, 2h5l:E, 2h5l:F, 2h5l:G, 2h5l:H, 1k0u:A, 1k0u:B, 1k0u:C, 1k0u:D, 1k0u:E, 1k0u:F, 1k0u:G, 1k0u:H, 1ky4:A, 1ky4:B, 1ky4:C, 1ky4:D, 1ky5:A, 1ky5:B, 1ky5:C, 1ky5:D, 1li4:A, 3nj4:A, 3nj4:B, 3nj4:C, 3nj4:D, 4pfj:A, 4pfj:B, 4pgf:A, 4pgf:B, 5w49:A, 5w49:B, 5w4b:A, 5w4b:B, 5w4b:C, 5w4b:D, 5w4b:E, 5w4b:F, 1xwf:A, 1xwf:B, 1xwf:C, 1xwf:D, 4yvf:A, 4yvf:B
12 6aph:A 432 467 0.5699 0.6134 0.5675 9.39e-176
13 6gbn:B 435 467 0.5591 0.5977 0.5567 1.82e-174 6gbn:A, 6gbn:C, 6gbn:D
14 3g1u:C 424 467 0.5656 0.6203 0.5632 3.13e-172 3g1u:A, 3g1u:B, 3g1u:D
15 3gvp:A 433 462 0.4667 0.5012 0.4697 2.67e-144 3gvp:B, 3gvp:C, 3gvp:D, 3mtg:A, 3mtg:B
16 8cfu:A 467 496 0.4925 0.4904 0.4617 5.97e-135 8ajs:AAA, 8ajs:DDD, 8ajs:BBB, 8ajs:CCC, 8ajt:AAA, 8ajt:DDD, 8ajt:BBB, 8ajt:CCC, 8aju:AAA, 8aju:CCC, 8ajv:AAA, 8ajv:DDD, 8ajv:BBB, 8ajv:CCC, 8ajv:FFF, 8ajv:III, 8ajv:GGG, 8ajv:HHH, 8ajw:AAA, 8ajw:DDD, 8ajw:BBB, 8ajw:CCC, 8azf:A, 8azf:C, 8cfb:A, 8cfb:D, 8cfb:B, 8cfb:C, 8cfc:A, 8cfc:D, 8cfc:B, 8cfc:C, 8cfd:A, 8cfd:D, 8cfd:B, 8cfd:C, 8cfe:A, 8cfe:D, 8cfe:B, 8cfe:C, 8cfg:A, 8cfg:D, 8cfg:B, 8cfg:C, 8cfh:A, 8cfh:D, 8cfh:B, 8cfh:C, 8cfi:A, 8cfi:D, 8cfi:B, 8cfi:C, 8cfj:A, 8cfj:D, 8cfj:B, 8cfj:C, 8cfk:A, 8cfk:D, 8cfk:B, 8cfk:C, 8cfl:A, 8cfl:D, 8cfl:B, 8cfl:C, 8cfm:A, 8cfm:D, 8cfm:B, 8cfm:C, 8cfn:A, 8cfn:C, 8cfo:A, 8cfo:D, 8cfo:B, 8cfo:C, 8cfp:A, 8cfp:D, 8cfp:B, 8cfp:C, 8cfq:A, 8cfq:D, 8cfq:B, 8cfq:C, 8cfr:A, 8cfr:D, 8cfr:B, 8cfr:C, 8cfs:A, 8cfs:D, 8cfs:B, 8cfs:C, 8cft:A, 8cft:D, 8cft:B, 8cft:C, 8cfu:D, 8cfu:B, 8cfu:C, 8cfv:A, 8cfv:D, 8cfv:B, 8cfv:C, 8cfw:A, 8cfw:D, 8cfw:B, 8cfw:C, 8cfx:A, 8cfx:D, 8cfx:B, 8cfx:C, 8cfx:G, 8cfx:J, 8cfx:H, 8cfx:I, 8cfy:A, 8cfy:D, 8cfy:B, 8cfy:C, 8cfy:G, 8cfy:J, 8cfy:H, 8cfy:I, 8cfz:A, 8cfz:D, 8cfz:B, 8cfz:C, 8cfz:H, 8cfz:K, 8cfz:I, 8cfz:J, 8cg0:A, 8cg0:D, 8cg0:B, 8cg0:C, 8cg1:A, 8cg1:D, 8cg1:B, 8cg1:C, 8cg1:G, 8cg1:J, 8cg1:H, 8cg1:I, 8cg2:A, 8cg2:C, 6f3m:A, 6f3m:B, 6f3m:C, 6f3m:D, 6f3n:A, 6f3n:B, 6f3n:C, 6f3n:D, 6f3o:A, 6f3o:B, 6f3o:C, 6f3o:D, 6f3p:A, 6f3p:C, 6f3q:A, 6f3q:B, 6f3q:C, 6f3q:D, 7zd0:A, 7zd0:D, 7zd0:B, 7zd0:C, 7zd1:A, 7zd1:D, 7zd1:B, 7zd1:C, 7zd2:A, 7zd2:D, 7zd2:B, 7zd2:C, 7zd3:A, 7zd3:D, 7zd3:B, 7zd3:C, 7zd4:A, 7zd4:D, 7zd4:B, 7zd4:C
17 7r39:A 412 448 0.4151 0.4684 0.4308 1.04e-114 7r39:B, 7r39:C, 7r39:D, 7r39:E, 7r39:F, 7r39:G, 7r39:H
18 8qno:A 421 450 0.4043 0.4466 0.4178 5.38e-102 8qno:B, 7r37:A, 7r37:B, 7r38:A, 7r38:B
19 7o5l:A 417 460 0.4129 0.4604 0.4174 5.32e-100 7o5l:C, 7o5m:A, 7o5m:C, 7zd7:A, 7zd7:C, 7zd8:A, 7zd8:C, 7zd9:A, 7zd9:C
20 7r3a:A 411 449 0.3828 0.4331 0.3964 3.21e-96 7r3a:B, 7r3a:C, 7r3a:D, 7r3a:E, 7r3a:F, 7r3a:G, 7r3a:H
21 3x2f:A 406 438 0.3398 0.3892 0.3607 2.18e-87 5tov:B, 5tow:B, 3x2e:A, 3x2e:B, 3x2e:C, 3x2e:D, 3x2f:B
22 5z20:F 336 189 0.1032 0.1429 0.2540 0.053 5z20:A, 5z20:B, 5z20:C, 5z20:D, 5z20:E
23 1lss:A 132 75 0.0473 0.1667 0.2933 0.20 1lss:B, 1lss:C, 1lss:D
24 8ep7:C 328 63 0.0387 0.0549 0.2857 0.45 8ep7:A, 8ep7:B
25 2ekl:A 312 92 0.0602 0.0897 0.3043 0.53
26 5va8:A 261 40 0.0323 0.0575 0.3750 0.69 5va8:B, 5va8:C, 5va8:D
27 6jx2:B 327 63 0.0387 0.0550 0.2857 0.81 6jx2:A, 6jx2:C, 6jx2:D
28 4cjx:A 297 122 0.0688 0.1077 0.2623 0.87 4cjx:B
29 8ijg:C 250 141 0.1011 0.1880 0.3333 0.95 8ij6:A, 8ij6:B, 8ij6:C, 8ij6:D, 8ijg:A, 8ijg:B, 8ijg:D
30 3aoe:B 424 54 0.0366 0.0401 0.3148 1.3 3aoe:A, 3aog:A, 3aog:E, 3aog:B, 3aog:D, 3aog:C, 3aog:F, 3aog:G, 3aog:I, 3aog:H, 3aog:J, 3aog:L, 3aog:K
31 8kd3:D 231 46 0.0301 0.0606 0.3043 1.6 8kd3:F, 8kd4:D, 8kd4:F, 8kd5:D, 8kd5:F, 8kd6:D, 8kd6:F
32 8iht:N 295 46 0.0301 0.0475 0.3043 1.7 8hxx:M, 8hxy:M, 8hxz:M, 8hy0:M, 8ihm:N, 8jho:M, 8jho:O, 8kd7:D, 8tof:D, 8tof:E, 7yi1:L, 7yi1:K, 7yi4:E, 7yi4:C, 7yi5:E, 7yi5:C
33 1bw9:A 350 58 0.0387 0.0514 0.3103 2.0 1bw9:B, 1bxg:A, 1bxg:B, 1c1d:A, 1c1d:B, 1c1x:A, 1c1x:B
34 5idy:B 264 35 0.0280 0.0492 0.3714 2.0 5idy:A, 5vps:A
35 4xiy:A 328 68 0.0473 0.0671 0.3235 2.0 4xiy:B, 4xiy:C, 4xiy:D
36 2bc0:A 473 54 0.0344 0.0338 0.2963 2.1 2bc0:B, 2bc1:A, 2bc1:B, 2bcp:A, 2bcp:B
37 6pej:A 257 205 0.1183 0.2140 0.2683 2.3 6pej:B, 6pej:C, 6pej:D
38 5mh5:A 308 95 0.0473 0.0714 0.2316 2.5 5mh5:B, 5mh6:A, 5mh6:B, 5mh6:C, 5mh6:D, 5mha:A, 5mha:B
39 5fwt:A 293 43 0.0301 0.0478 0.3256 3.1 5fws:A, 5fww:B
40 6rm3:LD0 282 128 0.0731 0.1206 0.2656 3.6
41 6bul:B 327 62 0.0409 0.0581 0.3065 3.8 6aqj:A, 6aqj:B, 6bul:A, 6c55:A, 6c55:B, 6c5n:A, 6c5n:B, 7ke2:B, 7ke2:A, 7kh7:A, 7kh7:B, 6vo2:A, 6vo2:B, 5w3k:A, 5w3k:B
42 3d3w:A 244 34 0.0280 0.0533 0.3824 3.9 3d3w:B, 1pr9:A, 1pr9:B, 1wnt:A, 1wnt:B, 1wnt:C, 1wnt:D
43 4wec:A 258 37 0.0344 0.0620 0.4324 4.4 4wec:B, 4wec:C, 4wec:D
44 1gpj:A 399 72 0.0452 0.0526 0.2917 4.8
45 2rgo:B 530 77 0.0538 0.0472 0.3247 6.8
46 6s2e:A 1006 37 0.0301 0.0139 0.3784 6.9 6s2f:A
47 5xf9:B 234 82 0.0473 0.0940 0.2683 7.1 5xf9:F, 5xfa:B, 5xfa:F
48 2vq3:A 181 116 0.0495 0.1271 0.1983 7.7 2vq3:B
49 3hjb:B 551 79 0.0495 0.0417 0.2911 8.5
50 5ztb:B 311 145 0.0731 0.1093 0.2345 9.4 5b4e:A, 5b4f:A, 5gha:A, 5gha:D, 5gha:B, 5gha:C, 5ztb:A, 5ztb:C

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218