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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
TGPLSVLTQSVKNNTQVLINCRNNKKLLGRVKAFDRHCNMVLENVKEMWTNKDRYISKMFLRGDSVIVVLRNPL

The query sequence (length=74) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8y6o:q 104 80 1.0000 0.7115 0.9250 4.46e-48 7a5p:h, 7abg:a, 7abi:a, 6ah0:k, 6ah0:P, 6ahd:P, 6ahd:k, 8ch6:l, 8ch6:4, 7dvq:k, 8h6e:2c, 8h6j:2c, 8h6k:4c, 8h6k:2c, 8h6l:4c, 8h6l:2c, 8i0w:k, 6id0:k, 6id1:k, 5o9z:h, 5o9z:a, 4pjo:R, 7qtt:l, 8qzs:42, 7w59:k, 7w5a:k, 7w5b:k, 5xjc:k, 8y7e:k, 5yzg:k, 5z56:k, 5z57:k, 5z58:k
2 4wzj:KK 104 89 1.0000 0.7115 0.8315 1.31e-46 7abg:h, 7abi:h, 6ahd:c, 7b0y:e, 8c6j:m, 8c6j:a, 7evo:a, 9fmd:k, 9fmd:d, 8h6e:5c, 8h6e:4c, 8h6j:5c, 8h6j:4c, 8h6k:5c, 8h6l:5c, 8hk1:a, 8i0p:c, 8i0p:h, 8i0r:c, 8i0r:h, 8i0s:c, 8i0s:h, 8i0t:h, 8i0u:c, 8i0u:h, 8i0v:c, 8i0v:h, 8i0w:c, 6icz:d, 6id0:d, 6id1:d, 5mqf:h, 5mqf:a, 4pjo:D, 4pjo:d, 4pjo:r, 8q7q:c, 8q7v:c, 8q7w:c, 8q7x:c, 8q91:j, 6qdv:m, 6qdv:j, 8qo9:22, 8qo9:52, 8qo9:42, 6qw6:42, 6qw6:52, 6qx9:12, 6qx9:52, 6qx9:22, 6qx9:42, 8qxd:22, 8qxd:42, 8qxd:52, 8qzs:52, 8qzs:22, 8r08:12, 8r08:42, 8r08:22, 8r08:52, 8r09:22, 8r09:52, 8r09:42, 8r0a:52, 8r0a:42, 8r0a:22, 8r0b:22, 8r0b:42, 8r0b:52, 8rc0:j, 8rm5:22, 8rm5:52, 8rm5:42, 8ro2:d, 7vpx:a, 7vpx:i, 7w59:d, 7w5a:d, 7w5b:d, 4wzj:D, 4wzj:K, 4wzj:R, 4wzj:DD, 4wzj:RR, 4wzj:DDD, 4wzj:KKK, 4wzj:RRR, 4wzj:DDDD, 4wzj:KKKK, 4wzj:RRRR, 5xjc:d, 6y53:h, 6y5q:h, 8y6o:c, 8y6o:j, 5yzg:d, 5z56:d, 5z57:d, 5z58:d
3 8ro0:d 94 76 0.8784 0.6915 0.8553 2.99e-43 8ro1:d
4 3jb9:G 95 85 0.8108 0.6316 0.7059 1.29e-37 3jb9:l
5 6n7p:M 107 80 0.6351 0.4393 0.5875 7.83e-30 7b9v:m, 7b9v:j, 6bk8:a, 7dco:n, 6exn:m, 6exn:j, 6g90:i, 6g90:u, 5gam:j, 5gan:m, 5gan:j, 5gao:m, 5gm6:g, 5gmk:g, 5gmk:e, 6j6g:g, 6j6g:e, 6j6h:g, 6j6h:e, 6j6n:g, 6j6n:e, 6j6q:g, 6j6q:e, 3jcm:Q, 3jcm:U, 5lj3:j, 5lj3:m, 5lj5:j, 5lj5:m, 5mps:j, 5mq0:j, 6n7r:M, 6n7x:M, 5nrl:u, 5nrl:m, 5nrl:i, 7oqb:u, 7oqc:i, 7oqe:i, 7oqe:u, 8w2o:M, 5wsg:g, 5wsg:W, 5y88:g, 5y88:n, 5ylz:g, 5ylz:n, 5zwm:R, 5zwm:c, 5zwm:n, 5zwn:c, 5zwo:c, 5zwo:R, 5zwo:n
6 6qw6:63 85 81 0.3243 0.2824 0.2963 6.92e-09 6ah0:r, 6qx9:63, 8qxd:63, 8r08:63, 8r09:63, 8r0a:63, 8r0b:63, 8rm5:63
7 5mkn:d 72 67 0.3243 0.3333 0.3582 1.43e-08 5mki:C, 5mki:D, 5mki:E, 5mki:F, 5mki:G, 5mki:I, 5mki:J, 5mki:K, 5mki:L, 5mkn:A, 5mkn:G, 5mkn:B, 5mkn:C, 5mkn:D, 5mkn:E, 5mkn:F, 5mkn:H, 5mkn:I, 5mkn:J, 5mkn:K, 5mkn:L, 5mkn:M, 5mkn:N, 5mkn:O, 5mkn:P, 5mkn:Q, 5mkn:R, 5mkn:T, 5mkn:U, 5mkn:V, 5mkn:W, 5mkn:X, 5mkn:Y, 5mkn:Z, 5mkn:a, 5mkn:b
8 6ppn:C 75 73 0.3243 0.3200 0.3288 1.10e-07 6ppn:K, 6ppp:C, 6ppp:K, 6ppq:C, 6ppv:C
9 1loj:C 77 73 0.2973 0.2857 0.3014 1.50e-07 1loj:A, 1loj:B, 1loj:D, 1loj:E, 1loj:F, 1loj:G, 1loj:H, 1loj:I, 1loj:J, 1loj:K, 1loj:L, 1loj:M, 1loj:N
10 5vsu:C 81 64 0.2703 0.2469 0.3125 5.60e-07 6aso:C, 4c8q:C, 5gan:3, 4m7a:J, 4m7a:C, 4m7d:J, 4m7d:C, 5nrl:3
11 1i5l:C 74 72 0.2838 0.2838 0.2917 4.37e-06 1i5l:E, 1i5l:F, 1i5l:G, 1i5l:J, 1i5l:K, 1i5l:L, 1i5l:A, 1i5l:B, 1i5l:H
12 1lnx:A 74 58 0.2297 0.2297 0.2931 8.20e-06 1lnx:B, 1lnx:C, 1lnx:D, 1lnx:E, 1lnx:F, 1lnx:G
13 6v4x:D 106 75 0.3108 0.2170 0.3067 4.11e-05
14 6ppq:A 69 62 0.2297 0.2464 0.2742 0.001 6ppv:A
15 1m8v:A 72 70 0.2973 0.3056 0.3143 0.002 1m8v:M, 1m8v:C, 1m8v:K, 1m8v:F, 1m8v:H, 1m8v:E, 1m8v:I, 1m8v:D, 1m8v:J, 1m8v:B, 1m8v:L, 1m8v:G, 1m8v:N
16 3jb9:E 98 49 0.1622 0.1224 0.2449 0.004 3jb9:b
17 6tfl:A 62 67 0.2432 0.2903 0.2687 0.006 6tfl:B, 6tfl:C, 6tfl:D, 6tfl:E, 6tfl:F, 6tfl:G, 6tfl:H, 6tfl:I, 6tfl:J, 6tfl:K, 6tfl:L, 6tfl:M, 6tfl:N
18 3jb9:H 76 70 0.2162 0.2105 0.2286 0.020 3jb9:m
19 7abg:j 81 68 0.2162 0.1975 0.2353 0.029 7a5p:j, 7a5p:e, 7abi:j, 6ah0:c, 6ahd:e, 7b0y:g, 8c6j:p, 8c6j:e, 8ch6:i, 8ch6:1, 7dvq:e, 7dvq:l, 9fmd:l, 9fmd:e, 8h6e:5e, 8h6e:4e, 8h6j:5e, 8h6j:4e, 8h6k:5e, 8h6l:5e, 8i0p:e, 8i0p:j, 8i0r:e, 8i0r:j, 8i0s:e, 8i0s:j, 8i0t:e, 8i0t:j, 8i0u:e, 8i0u:j, 8i0v:e, 8i0v:j, 8i0w:e, 8i0w:l, 6icz:e, 6id0:e, 6id1:e, 5mqf:j, 5mqf:c, 5o9z:j, 4pjo:E, 4pjo:e, 4pjo:S, 4pjo:s, 8q7q:e, 8q7v:e, 8q7w:e, 8q7x:e, 6qdv:p, 6qdv:e, 8qo9:2e, 8qo9:5e, 8qo9:4e, 7qtt:i, 6qw6:4e, 6qw6:5e, 6qx9:1e, 6qx9:5e, 6qx9:2e, 6qx9:4e, 8qxd:2e, 8qxd:4e, 8qzs:5e, 8qzs:2e, 8qzs:4e, 8r08:1e, 8r08:2e, 8r08:4e, 8r09:2e, 8r09:5e, 8r09:4e, 8r0a:5e, 8r0a:2e, 8r0a:4e, 8r0b:4e, 8r0b:5e, 8rm5:2e, 8rm5:5e, 8rm5:4e, 8ro2:e, 6v4x:E, 7vpx:l, 7w59:e, 7w59:l, 7w5a:e, 7w5a:l, 7w5b:e, 7w5b:l, 4wzj:E, 4wzj:L, 4wzj:S, 4wzj:EE, 4wzj:LL, 4wzj:SS, 4wzj:EEE, 4wzj:LLL, 4wzj:SSS, 4wzj:EEEE, 4wzj:LLLL, 4wzj:SSSS, 5xjc:e, 5xjc:l, 8y6o:e, 8y6o:l, 8y6o:s, 8y7e:l, 5yzg:e, 5yzg:l, 5z56:e, 5z56:l, 5z57:e, 5z57:l, 5z58:e, 5z58:l
20 6v4x:B 76 47 0.1757 0.1711 0.2766 0.035
21 8ro0:b 98 55 0.1892 0.1429 0.2545 0.038 8ro1:b
22 9fmd:b 87 46 0.1757 0.1494 0.2826 0.071 7a5p:m, 7a5p:b, 7abg:f, 7abi:f, 6ah0:U, 8ch6:n, 5o9z:f, 6qdv:b, 7qtt:n, 4wzj:I, 4wzj:P, 4wzj:BB, 4wzj:II, 4wzj:PP, 4wzj:BBB, 4wzj:III, 4wzj:PPP, 4wzj:BBBB, 4wzj:IIII, 4wzj:PPPP
23 3swn:A 76 70 0.2297 0.2237 0.2429 0.099 6ppq:E, 6ppv:E, 3swn:D, 3swn:P, 3swn:S
24 6qw6:68 95 69 0.2297 0.1789 0.2464 0.11 6ahd:z, 8h6e:6g, 8h6j:6g, 8h6k:6g, 8h6l:6g, 6qx9:68, 8qxd:68, 8r08:68, 8r09:68, 8r0a:68, 8r0b:68, 8rm5:68
25 6bk8:f 80 60 0.2568 0.2375 0.3167 0.16 6bk8:k, 7dco:a, 7dco:h, 6exn:k, 6exn:b, 6g90:s, 5gam:b, 5gan:k, 5gan:b, 5gao:k, 5gm6:k, 5gmk:k, 5gmk:s, 3jcm:S, 5lj3:b, 5lj5:b, 5mps:b, 5mq0:k, 5mq0:b, 5nrl:s, 5nrl:k, 5nrl:b, 7oqb:s, 7oqe:s, 5wsg:k, 5wsg:F, 5y88:a, 5y88:h, 5ylz:a, 5ylz:h, 5zwm:P, 5zwm:a, 5zwm:h, 5zwo:a, 5zwo:P
26 6ppn:B 94 56 0.2027 0.1596 0.2679 0.22 6ppn:J, 6ppp:B, 6ppp:J, 6ppq:B, 6ppv:B
27 7w59:b 102 57 0.1892 0.1373 0.2456 0.25 7abg:m, 7abi:m, 6ahd:a, 7b0y:j, 8c6j:b, 8ch6:8, 7dvq:i, 9fmd:i, 8h6e:5a, 8h6e:4a, 8h6j:5a, 8h6j:4a, 8h6k:5a, 8h6l:5a, 8i0p:a, 8i0p:m, 8i0r:a, 8i0r:m, 8i0s:m, 8i0t:a, 8i0t:m, 8i0u:m, 8i0v:a, 8i0v:m, 8i0w:a, 8i0w:i, 6icz:i, 4pjo:B, 4pjo:b, 4pjo:P, 4pjo:p, 8q7q:b, 8q7v:b, 8q7w:b, 8q7x:b, 8q91:h, 6qdv:k, 8qo9:5b, 8qo9:4b, 6qw6:4b, 6qw6:5b, 6qx9:1b, 6qx9:5b, 6qx9:2b, 6qx9:4b, 8qxd:4b, 8qxd:5b, 8qzs:5b, 8qzs:2b, 8r08:1b, 8r08:4b, 8r08:5b, 8r09:5b, 8r0a:5b, 8r0b:5b, 8rc0:h, 8rm5:2b, 8rm5:5b, 8ro2:b, 7vpx:k, 7w59:i, 7w5a:b, 7w5a:i, 7w5b:b, 7w5b:i, 4wzj:B, 5xjc:b, 5xjc:i, 8y6o:a, 8y6o:h, 8y6o:o, 8y7e:i, 5yzg:b, 5yzg:i, 5z56:b, 5z56:i, 5z57:b, 5z57:i, 5z58:b, 5z58:i
28 6exn:r 75 58 0.1892 0.1867 0.2414 0.45 7b9v:r, 7b9v:g, 6bk8:d, 7dco:k, 6exn:g, 6g90:g, 6g90:y, 5gam:g, 5gan:r, 5gan:g, 5gao:r, 5gm6:j, 5gmk:j, 5gmk:x, 6j6g:j, 6j6g:x, 6j6h:j, 6j6h:x, 6j6n:j, 6j6n:x, 6j6q:j, 6j6q:x, 5lj3:g, 5lj5:g, 5mps:g, 5mq0:g, 6n7p:Q, 6n7r:Q, 6n7x:Q, 5nrl:y, 5nrl:r, 5nrl:g, 7oqb:y, 7oqc:g, 7oqe:y, 8w2o:Q, 5wsg:j, 5wsg:K, 5y88:d, 5y88:k, 5ylz:d, 5ylz:k, 5zwm:V, 5zwm:k, 5zwn:g, 5zwo:k
29 4gfh:A 1102 64 0.2432 0.0163 0.2812 0.54 4gfh:F, 3l4j:A, 3l4k:A, 1pvg:A, 1pvg:B, 1qzr:A, 1qzr:B, 2rgr:A
30 6ppn:H 94 68 0.2432 0.1915 0.2647 0.61 6ppn:P, 6ppp:H, 6ppp:P
31 6v4x:G 77 48 0.1757 0.1688 0.2708 1.4 7a5p:k, 7a5p:g, 7abg:k, 7abi:k, 6ah0:n, 6ahd:S, 6ahd:f, 6ahd:n, 7b0y:h, 8c6j:r, 8c6j:g, 8ch6:m, 8ch6:9, 7dvq:g, 7dvq:n, 7evo:d, 9fmd:n, 9fmd:g, 8h6e:5f, 8h6e:4f, 8h6e:2f, 8h6j:5f, 8h6j:4f, 8h6j:2f, 8h6k:5f, 8h6k:4f, 8h6k:2f, 8h6l:5f, 8h6l:4f, 8h6l:2f, 8hk1:d, 8i0p:k, 8i0r:k, 8i0s:f, 8i0s:k, 8i0t:k, 8i0u:f, 8i0u:k, 8i0v:k, 8i0w:n, 6icz:g, 6id0:g, 6id1:g, 5mqf:k, 5mqf:d, 5o9z:k, 4pjo:G, 4pjo:g, 4pjo:U, 4pjo:u, 8q7q:g, 8q7v:g, 8q7w:g, 8q7x:g, 8q91:n, 6qdv:r, 6qdv:g, 8qo9:2g, 8qo9:4g, 7qtt:m, 6qw6:4g, 6qw6:5g, 6qx9:1g, 6qx9:5g, 6qx9:2g, 6qx9:4g, 8qxd:2g, 8qxd:4g, 8qxd:5g, 8qzs:5g, 8qzs:2g, 8qzs:4g, 8r08:1g, 8r08:2g, 8r08:4g, 8r08:5g, 8r09:2g, 8r09:5g, 8r09:4g, 8r0a:5g, 8r0a:2g, 8r0a:4g, 8r0b:2g, 8r0b:4g, 8r0b:5g, 8rc0:n, 8rm5:2g, 8rm5:5g, 8rm5:4g, 8ro2:g, 7vpx:d, 7vpx:n, 7w59:g, 7w59:n, 7w5a:g, 7w5a:n, 7w5b:g, 7w5b:n, 4wzj:G, 4wzj:N, 4wzj:U, 4wzj:GG, 4wzj:NN, 4wzj:UU, 4wzj:GGG, 4wzj:NNN, 4wzj:UUU, 4wzj:GGGG, 4wzj:NNNN, 4wzj:UUUU, 5xjc:g, 5xjc:n, 6y53:k, 6y5q:k, 8y6o:g, 8y6o:n, 8y6o:u, 8y7e:n, 5yzg:g, 5yzg:n, 5z56:g, 5z56:n, 5z57:g, 5z57:n, 5z58:g, 5z58:n
32 8ro0:n 77 48 0.1622 0.1558 0.2500 4.9 8ro0:g, 8ro1:g
33 7ziu:B 606 23 0.0946 0.0116 0.3043 6.7 7ziu:A
34 6n7r:K 124 15 0.1081 0.0645 0.5333 7.5 7b9v:k, 7b9v:b, 6g90:b, 6j6g:k, 6j6g:s, 6j6h:k, 6j6h:s, 6j6n:k, 6j6n:s, 6j6q:k, 6j6q:s, 6n7p:K, 6n7x:K, 7oqc:b, 7oqe:b, 8w2o:K, 5zwn:a
35 6vya:C 387 52 0.1622 0.0310 0.2308 7.7 6vya:A, 6vya:V, 6vya:E, 6vya:G, 6vya:B, 6vya:D, 6vya:F, 6vya:H, 6vya:I, 6vya:J, 6vya:K, 6vya:L, 6vya:M, 6vya:N, 6vya:O, 6vya:P, 6vya:Q, 6vya:R, 6vya:S, 6vya:T, 6vya:U, 6vya:W, 6vya:X
36 6jig:A 480 40 0.1486 0.0229 0.2750 9.1 6lk4:A
37 8cem:B 974 24 0.1486 0.0113 0.4583 9.2
38 6ykg:AAA 559 28 0.1486 0.0197 0.3929 9.8 5anl:A, 5enn:A, 5enn:B, 6i3u:A, 3ls8:A, 3ls8:B, 4oys:A, 4ph4:B, 7rsj:A, 7rsp:A, 7rsp:B, 7rsv:A, 7rsv:B, 8rxr:A, 8rxr:B, 4uwf:A, 4uwg:A, 4uwh:A, 4uwk:A, 4uwl:A
39 5gqo:A 97 21 0.1351 0.1031 0.4762 10.0

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218