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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
STNITFHASALTRSERTELRNQRGLTIWLTGLSASGKSTLAVELEHQLVRDRRVHAYRLDGDNIRFGLNKDLGFSEADRN
ENIRRIAEVAKLFADSNSIAITSFISPYRKDRDTARQLHEVATPGEETGLPFVEVYVDVPVEVAEQRDPKGLYKKAREGV
IKEFTGISAPYEAPANPEVHVKNYELPVQDAVKQIIDYLDTKGYLPAK

The query sequence (length=208) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 1m7g:C 209 208 1.0000 0.9952 1.0000 1.29e-154 3cr7:A, 3cr7:B, 3cr7:C, 3cr7:D, 1m7g:A, 1m7g:B, 1m7g:D, 1m7h:A, 1m7h:B, 1m7h:C, 1m7h:D
2 6c6b:B 199 207 0.6010 0.6281 0.6039 2.28e-87 6c6b:A, 6c6b:C, 6c6b:D, 6c6b:E, 6c6b:F
3 4fxp:B 200 212 0.5240 0.5450 0.5142 6.53e-68 4fxp:A, 4fxp:C, 3uie:A, 3uie:B, 3uie:C
4 2ax4:A 198 184 0.4760 0.5000 0.5380 3.75e-66 2ax4:B, 2ax4:C, 2ax4:D, 8i1n:A, 8i1n:B, 8i1n:C, 8i1n:D, 8i1o:A, 8i1o:B, 8i1o:C, 8i1o:D
5 1xjq:B 590 184 0.5000 0.1763 0.5652 1.06e-63 8i1m:A, 2ofw:A, 2ofw:B, 2ofw:C, 2ofw:D, 2ofw:E, 2ofw:F, 2ofw:G, 2ofw:H, 2ofx:A, 2ofx:B, 2pey:A, 2pez:A, 2pez:B, 2qjf:A, 2qjf:B, 1x6v:B, 1xnj:B
6 4bzp:A 173 179 0.3894 0.4682 0.4525 7.39e-52 4bzp:B, 4bzq:A, 4bzq:B, 4bzx:A, 4bzx:B
7 1xjq:A 563 184 0.4087 0.1510 0.4620 5.17e-45 2pey:B, 1xnj:A
8 2gks:B 529 203 0.4038 0.1588 0.4138 9.56e-44 2gks:A
9 5cb8:B 176 175 0.3846 0.4545 0.4571 3.58e-42 5cb6:A, 5cb6:B, 5cb6:C, 5cb6:D, 5cb6:E, 5cb6:F, 5cb8:A
10 7yq0:A 173 184 0.3654 0.4393 0.4130 2.14e-35 7yq0:B, 7yq1:A, 7yq1:B, 7yq1:C, 7yq1:D, 7yq1:E, 7yq1:F
11 1m8p:A 573 186 0.3317 0.1204 0.3710 6.62e-24 1i2d:A, 1i2d:B, 1i2d:C, 1m8p:B, 1m8p:C
12 8a8h:B 146 182 0.2981 0.4247 0.3407 9.47e-23
13 1kkm:B 177 55 0.1058 0.1243 0.4000 0.071 1kkl:A, 1kkl:B, 1kkl:C, 1kkm:A, 1kkm:C
14 1ko5:A 172 176 0.2019 0.2442 0.2386 0.081 1ko5:B, 1ko8:A, 1kof:A, 1kof:B
15 8rbx:b 1051 50 0.0721 0.0143 0.3000 0.21 7pks:b, 8rbz:b
16 3uwx:A 945 21 0.0625 0.0138 0.6190 2.9
17 2r6f:B 879 21 0.0625 0.0148 0.6190 3.1
18 2r6f:A 899 21 0.0625 0.0145 0.6190 3.1
19 3ux8:A 564 21 0.0625 0.0230 0.6190 3.3
20 4ke8:C 249 42 0.0769 0.0643 0.3810 3.4 4ke6:A, 4ke7:A, 4ke7:B, 4ke8:A, 4ke8:B, 4ke8:D, 4ke9:A, 4ke9:B, 4ke9:C, 4ke9:D
21 3dx5:A 274 80 0.1058 0.0803 0.2750 4.1
22 7p48:6 510 144 0.1490 0.0608 0.2153 5.9
23 5xbp:A 444 32 0.0577 0.0270 0.3750 6.1 5xbp:D, 5xbp:G
24 4gnc:A 298 72 0.1010 0.0705 0.2917 8.6 3g4e:A, 3g4e:B, 3g4h:B, 3g4h:A, 4gnb:A, 4gnb:B, 4gnc:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218