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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
SRIPVVLLACGSFNPITNMHLRMFEVARDHLHQTGMYQVIQGIISPVNDTYGKKDLAASHHRVAMARLALQTSDWIRVDP
WESEQAQWMETVKVLRHHHSKLLRVPELKLLCGADVLKTFQTPNLWKDAHIQEIVEKFGLVCVGRVSHDPKGYIAESPIL
RMHQHNIHLAKEPVQNEISATYIRRALGQGQSVKYLIPDAVITYIKDHGLYT

The query sequence (length=212) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 1nup:A 213 212 0.9953 0.9906 0.9953 5.31e-160 1nup:B, 1nuq:A, 1nuq:B, 1nus:A, 1nus:B, 1nut:A, 1nut:B, 1nuu:A, 1nuu:B
2 1kqo:A 233 212 0.5613 0.5107 0.5613 5.50e-88 1gzu:A, 1gzu:B, 1gzu:C, 1kqn:A, 1kqn:B, 1kqn:C, 1kqn:D, 1kqn:E, 1kqn:F, 1kqo:B, 1kqo:C, 1kqo:D, 1kqo:E, 1kqo:F, 1kr2:A, 1kr2:B, 1kr2:C, 1kr2:D, 1kr2:E, 1kr2:F, 8qe8:4, 8qe8:3
3 1kaq:A 186 206 0.2642 0.3011 0.2718 3.28e-12 1kaq:B, 1kaq:C, 1kaq:D, 1kaq:E, 1kaq:F
4 8aih:A 184 209 0.2500 0.2880 0.2536 4.74e-10 8aii:A, 9fyb:A, 9fyb:B
5 2h2a:A 189 211 0.2594 0.2910 0.2607 3.15e-08 2h29:A, 2h29:B, 2h2a:B
6 1yum:A 212 226 0.2500 0.2500 0.2345 6.47e-08 1yum:B, 1yum:C, 1yum:D, 1yun:A, 1yun:B
7 1k4m:A 213 222 0.2830 0.2817 0.2703 1.32e-06 1k4m:B, 1k4m:C
8 4wso:A 227 122 0.1792 0.1674 0.3115 5.06e-06 4wso:B
9 5db4:B 175 205 0.2311 0.2800 0.2390 7.81e-06
10 4ymi:B 198 207 0.2358 0.2525 0.2415 2.12e-05 5db4:A, 5deo:A, 5deo:B, 5deo:C, 5deo:D, 5vir:A, 5vir:B, 4ymi:A
11 5das:A 198 202 0.2217 0.2374 0.2327 2.54e-05 6buv:B, 4s1o:A, 4ybr:A, 4ybr:B
12 5das:C 180 203 0.2264 0.2667 0.2365 0.022 5das:B, 5das:D, 4s1o:B
13 1f9a:A 164 95 0.1132 0.1463 0.2526 0.32 1f9a:B, 1f9a:C, 1f9a:D, 1f9a:E, 1f9a:F
14 3e27:C 189 34 0.0566 0.0635 0.3529 0.33 3e27:A, 3e27:B, 3e27:D, 3hfj:A, 3hfj:B, 3mla:A, 3mla:B, 3mlb:A, 3mlb:B, 3mmx:B, 3mmx:C, 3mmx:A, 3mmx:D, 2qtn:B, 2qtr:A, 2qtr:B, 2qtr:C
15 5z9y:B 234 56 0.0708 0.0641 0.2679 0.36 5z9y:A
16 6ayh:A 192 68 0.0802 0.0885 0.2500 0.57
17 8ouw:D 203 38 0.0660 0.0690 0.3684 1.1
18 3l92:A 159 57 0.0849 0.1132 0.3158 1.6
19 6pnz:A 293 107 0.1368 0.0990 0.2710 2.0 6pnz:B, 6pnz:C
20 5c0w:K 576 100 0.0849 0.0312 0.1800 2.4 5c0y:B, 5c0y:A, 2hbk:A, 2hbl:A, 2hbm:A, 5k36:J, 4oo1:J, 4wfd:A
21 7cpx:A 2262 75 0.1038 0.0097 0.2933 4.0 7cpx:B, 7cpy:A, 7cpy:B
22 7o4x:A 103 32 0.0660 0.1359 0.4375 4.0
23 3otw:A 157 93 0.0943 0.1274 0.2151 6.3 3otw:D, 3otw:B, 3otw:C, 3otw:E, 3otw:F
24 3ty7:B 454 76 0.1085 0.0507 0.3026 6.4
25 8hui:C 399 54 0.0708 0.0376 0.2778 6.7 8hui:A, 8hui:B
26 4k6n:A 352 60 0.0802 0.0483 0.2833 8.2
27 7dwa:B 327 75 0.0802 0.0520 0.2267 8.4 7dvj:B, 7dvj:A, 7dw8:A, 7dw8:B, 7dwa:A
28 7oj1:A 401 46 0.0755 0.0399 0.3478 8.5

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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