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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
SRALYFSGRGEQLRLRADLELPRDAFTLQVWLRAEGGQRSPAVITGLYDKCSYISRDRGWVVGIHTISDQDNKDPRYFFS
LKTDRARQVTTINAHRSYLPGQWVYLAATYDGQFMKLYVNGAQVATSGEQVGGIFSPLTQKCKVLMLGGSALNHNYRGYI
EHFSLWKVARTQREILSDMETHGAHTALPQLLLQENWDNVKHAWSPMKDGSSPKVEFSNAHGFLLDTSLEPPLCGQTLCD
NTEVIASYNQLSSFRQPKVVRYRVVNLYEDDHKNPTVTREQVDFQHHQLAEAFKQYNISWELDVLEVSNSSLRRRLILAN
CDISKIGDENCDPECNHTLTGHDGGDCRHLRHPAFVKKQHNGVCDMDCNYERFNFDGGECCDPEITNVTQTCFDPDSPHR
AYLDVNELKNILKLDGSTHLNIFFAKSSEEELAGVATWPWDKEALMHLGGIVLNPSFYGMPGHTHTMIHQIGHSLGLYHV
FRGISEIQSCSDPCMETEPSFETGDLCNDTNPAPKHKSCGDPGPGNDTCGFHSFFNTPYNNFMSYADDDCTDSFTPNQVA
RMHCYLDLVYQGWQPSRKPAPVALAPQVLGHTTDSVTLEWFPPIDGHFFERELGSACHLCLEGRILVQYASNASSPMPCS
PSGHWSPREAEGHPDVEQPCKSSVRTWSPNSAVNPHTVPPACPEPQGCYLELEFLYPLVPESLTIWVTFVSTDWDSSGAV
NDIKLLAVSGKNISLGPQNVFCDVPLTIRLWDVGEEVYGIQIYTLDEHLEIDAAMLTSTADTPLCLQCKPLKYKVVRDPP
LQMDVASILHLNRKFVDMDLNLGSVYQYWVITISGTEESEPSPAVTYIHGSGYCGDGIIQKDQGEQCDDMNKINGDGCSL
FCRQEVSFNCIDEPSRCYFHDGDGVCEEFEQKTSIKDCGVY

The query sequence (length=921) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8a7e:C 1524 921 1.0000 0.6043 1.0000 0.0 8a7d:C, 8a7e:Q, 7y5n:C, 7y5q:B
2 8hgg:C 1484 921 0.9989 0.6199 0.9989 0.0 8hgg:D, 8hgh:A, 8hgh:B
3 7ufg:B 1182 921 0.9262 0.7217 0.9262 0.0 8d8o:B
4 7ufg:A 1151 526 0.5440 0.4353 0.9525 0.0
5 7ufg:A 1151 320 0.3474 0.2780 1.0000 0.0
6 8sl1:A 843 906 0.4473 0.4887 0.4547 0.0
7 8cdb:A 306 130 0.0413 0.1242 0.2923 3.66e-05 8cd8:A, 8cd8:C, 8cdb:B, 8cdb:C, 8cdb:D, 8cdb:E, 8cdb:F, 8cdb:G, 8cdb:H, 8cdb:I, 8cdb:J, 8cdb:K, 8cdb:L, 8cdb:M, 8cdb:N, 2cki:A, 2cki:B, 2j83:A, 2j83:B, 3lum:A, 3lum:B, 3lum:C, 3lum:D, 3lun:A, 3lun:B
8 6r7u:B 308 157 0.0434 0.1299 0.2548 2.06e-04 7od0:AAA, 7od0:BBB, 7od0:CCC, 7od0:DDD, 7od0:EEE, 7od0:FFF, 6r7u:A, 6r7v:A, 6r7w:A
9 2rgo:B 530 132 0.0369 0.0642 0.2576 0.58
10 8w0a:C 636 130 0.0337 0.0487 0.2385 0.64 8w0a:A
11 4zlp:A 241 24 0.0152 0.0581 0.5833 0.82 5czv:A, 5czx:A, 5czx:B, 6xsw:C, 6xsw:F, 6xsw:J, 6xsw:X, 4zlp:B
12 7r81:H1 194 43 0.0152 0.0722 0.3256 0.94
13 3b4n:A 314 49 0.0195 0.0573 0.3673 1.2 3b4n:B, 3b8y:A, 3b90:A, 3b90:B
14 9asj:A 741 140 0.0369 0.0459 0.2429 2.4 9asj:B, 9bp9:A, 9bp9:C, 9bpa:A, 9bpa:C, 9bpa:E, 9bpa:G
15 2rgo:A 557 122 0.0326 0.0539 0.2459 2.5 2rgh:A
16 1t90:A 484 110 0.0326 0.0620 0.2727 4.6 1t90:B, 1t90:C, 1t90:D
17 3tr8:A 184 109 0.0261 0.1304 0.2202 5.1 3tr8:B
18 9bha:A 793 143 0.0369 0.0429 0.2378 5.2 5a9f:A, 5aga:A, 9bh8:A, 9bh8:B, 9bh9:A, 9bh9:B, 9bha:B, 9c5q:C, 9c5q:A
19 6e85:A 331 45 0.0195 0.0544 0.4000 5.2
20 3u5z:B 320 35 0.0109 0.0312 0.2857 5.3 3u5z:C, 3u5z:D, 3u5z:E, 3u5z:L, 3u5z:M, 3u5z:N, 3u5z:O, 3u60:B, 3u60:C, 3u60:D, 3u60:E, 3u61:C, 3u61:D, 3u61:E, 3u61:B, 8uh7:B, 8uh7:C, 8uh7:D, 8uh7:E, 8uk9:B, 8uk9:C, 8uk9:D, 8uk9:E, 8uk9:K, 8uk9:L, 8uk9:M, 8uk9:N, 8unf:E, 8unf:D, 8unf:C, 8unf:B, 8unh:B, 8unh:E
21 5ho2:A 803 81 0.0228 0.0262 0.2593 6.2 5ho0:A, 5ho9:A, 5ho9:B, 5hof:A, 5hon:A, 5hon:B, 5hp6:A
22 4lwp:B 342 60 0.0217 0.0585 0.3333 6.7 4lwp:A
23 1r54:A 206 18 0.0130 0.0583 0.6667 7.2 1r55:A
24 6a48:A 651 114 0.0326 0.0461 0.2632 7.4
25 2y7d:D 278 30 0.0163 0.0540 0.5000 8.1 2y7d:A, 2y7d:B, 2y7d:C, 2y7e:A, 2y7e:B, 2y7f:A, 2y7f:B, 2y7f:C, 2y7f:D, 2y7g:A, 2y7g:B
26 7abv:A 232 63 0.0228 0.0905 0.3333 8.1 3eto:A, 3eto:B, 3i08:A, 3i08:C, 3l95:X, 3l95:Y

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218