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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
SMAFPKRLEIGGHALVWSGDWSAAGARKAIAGAARAGFDYIEIALLDPWQIDVALTKDLLQEYNLRAHASLGLSAATDVT
STDPAIVAKGDELLRKATDVLYALGGSELCGVIYCALGKYPGPASRENRANSVAAMQRLADYAADKGINIDLEVVNRYET
NIMNTGLEGLAFLDEVNRPNAFLHLDTYHMNIEENGMAKSVLAAGDRLGYVHIGESHRGYLGTGNVDFASFFAALKQIDY
RGPITFESFSSEIVDPKLSNTLCVWRNLWHDSDDLAGKALEFIKQRLT

The query sequence (length=288) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7cj5:A 292 284 0.9792 0.9658 0.9930 0.0 7cj4:A, 7cj4:B, 7cj5:B, 7cj6:A, 7cj6:B, 7cj7:A, 7cj7:B, 7cj8:A, 7cj8:B, 7cj8:C, 7cj8:D, 7cj8:E, 7cj8:F, 7cj9:A, 7cj9:B, 7cj9:C, 7cj9:D, 7cj9:E, 7cj9:F, 7cj9:G, 7cj9:H
2 5zfs:B 294 281 0.5451 0.5340 0.5587 1.04e-111 5zfs:A
3 3vyl:A 297 274 0.4028 0.3906 0.4234 1.07e-75 3vyl:B, 3vyl:C, 3vyl:D, 3vyl:E, 3vyl:F, 3vyl:G, 3vyl:H
4 7ern:C 284 278 0.3542 0.3592 0.3669 3.91e-55 7erm:A, 7erm:B, 7erm:C, 7erm:D, 7ern:A, 7ern:B, 7ern:D, 7ero:A, 7ero:B, 7ero:C, 7ero:D
5 7dz4:C 286 279 0.3507 0.3531 0.3620 8.07e-55 7dz2:A, 7dz2:B, 7dz2:C, 7dz2:D, 7dz3:A, 7dz3:B, 7dz3:C, 7dz3:D, 7dz4:A, 7dz4:B, 7dz4:D, 7dz5:A, 7dz5:B, 7dz5:C, 7dz5:D, 7dz6:A, 7dz6:B, 7dz6:C, 7dz6:D
6 4pfh:A 298 292 0.3194 0.3087 0.3151 1.61e-40 5j8l:A, 5j8l:B, 5j8l:C, 5j8l:D, 2ou4:A, 2ou4:B, 2ou4:C, 2ou4:D, 4pfh:B, 4pgl:A, 4pgl:B, 4pgl:C, 4pgl:D, 4q7i:A, 4q7i:B, 2qul:A, 2qul:B, 2qul:C, 2qul:D, 2qum:A, 2qum:B, 2qum:C, 2qum:D, 2qun:A, 2qun:B, 2qun:C, 2qun:D, 4xsl:A, 4xsl:B, 4xsl:C, 4xsl:D, 4xsm:A, 4xsm:B, 4xsm:C, 4xsm:D, 4ytq:A, 4ytq:B, 4ytq:C, 4ytq:D, 4ytr:A, 4ytr:B, 4ytr:C, 4ytr:D, 4yts:A, 4yts:B, 4yts:C, 4yts:D, 4ytt:A, 4ytt:B, 4ytt:C, 4ytt:D, 4ytu:A, 4ytu:B, 4ytu:C, 4ytu:D
7 2hk1:A 289 257 0.2708 0.2699 0.3035 9.48e-33 2hk1:B, 2hk1:C, 2hk1:D
8 3vnl:A 291 263 0.2569 0.2543 0.2814 7.73e-27 7e9w:A, 7e9w:B, 7e9w:C, 7e9w:D, 3vni:A, 3vni:B, 3vni:C, 3vni:D, 3vnj:A, 3vnj:B, 3vnj:C, 3vnj:D, 3vnk:A, 3vnk:B, 3vnk:C, 3vnk:D, 3vnl:B, 3vnl:C, 3vnl:D, 3vnm:A, 3vnm:B, 3vnm:C, 3vnm:D
9 7x7w:A 288 263 0.2674 0.2674 0.2928 9.08e-27 7x7w:B
10 5h1w:A 270 244 0.2674 0.2852 0.3156 1.23e-25 5b7y:A, 5b7y:B, 5b80:A, 5b80:B, 5h1w:B, 5h6h:A, 5h6h:B
11 6wn6:B 264 223 0.2118 0.2311 0.2735 7.47e-16 6wn6:A, 6wn6:C, 6wn6:D
12 2qw5:A 327 253 0.2083 0.1835 0.2372 1.02e-12 2qw5:B
13 3kws:A 265 176 0.1562 0.1698 0.2557 6.74e-09 3kws:B
14 1i6n:A 278 234 0.1910 0.1978 0.2350 1.92e-08
15 3cqj:A 276 238 0.2118 0.2210 0.2563 2.21e-07 3cqj:B, 3cqk:A, 3cqk:B
16 3ngf:B 260 216 0.1701 0.1885 0.2269 2.75e-06 3ngf:A
17 3tva:A 282 152 0.1424 0.1454 0.2697 1.97e-05 3tva:B
18 1k77:A 260 228 0.1840 0.2038 0.2325 4.66e-05
19 3wqo:A 271 125 0.1042 0.1107 0.2400 0.004 3wqo:B
20 5hmq:D 624 130 0.0972 0.0449 0.2154 0.030 5hmq:A, 5hmq:B, 5hmq:C, 5hmq:E, 5hmq:F
21 6yx5:B 339 71 0.0729 0.0619 0.2958 0.14
22 7vpf:A 273 133 0.1007 0.1062 0.2180 0.21 7vpf:B
23 6mss:A 181 68 0.0694 0.1105 0.2941 0.37
24 1txo:B 236 22 0.0521 0.0636 0.6818 0.65 2cm1:A, 1txo:A
25 5vkt:A 353 43 0.0556 0.0453 0.3721 0.96 5vkt:B
26 5j7i:B 456 85 0.0972 0.0614 0.3294 1.6 5j7i:C, 5j7i:D
27 3zd7:A 623 128 0.1042 0.0482 0.2344 2.6 8g7t:C
28 5x7o:A 1247 123 0.1042 0.0241 0.2439 2.7 5x7o:B, 5x7p:B, 5x7p:A, 5x7q:A, 5x7q:B, 5x7r:A, 5x7r:B, 5x7s:A, 5x7s:B
29 1yqd:A 359 35 0.0486 0.0390 0.4000 4.6 1yqd:B, 1yqx:A, 1yqx:B
30 1e6y:F 247 52 0.0660 0.0769 0.3654 5.4 1e6y:C, 8gf5:E
31 2c1w:B 276 67 0.0660 0.0688 0.2836 5.9 2c1w:A, 2c1w:C
32 8ro4:A 339 66 0.0764 0.0649 0.3333 6.6 8ro4:C, 8ro4:D, 8ro4:B, 8ro4:E, 8ro4:F

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218