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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
SKKSHKDKAKHAVVLDQDKFDRIMKEAPTYRYVSVSVLVDRFKLGGSLARVALRHLENEGIIKPVSKHSKQAIYTRAT

The query sequence (length=78) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6fyx:Z 78 78 1.0000 1.0000 1.0000 1.05e-52 6fyy:Z, 6gsm:Z, 6gsn:Z, 8i7j:Z, 5it7:Z, 5it9:Z, 3j80:Z, 3j81:Z, 3jam:Z, 3jap:Z, 8rw1:Z, 8s8d:Z, 8s8e:Z, 8s8f:Z, 8s8g:Z, 8s8h:Z, 8s8i:Z, 8s8j:Z, 6uz7:Z
2 7rr5:SZ 100 72 0.7692 0.6000 0.8333 3.18e-42 7a1g:L, 7b7d:K, 8bn3:D5, 8bqd:K, 8bqx:K, 8c00:K, 8c01:K, 8cah:L, 8cas:M, 8cbj:Z, 8ccs:1, 8cdl:1, 8cdr:1, 8ceh:1, 8cf5:1, 8cg8:1, 8cgn:1, 8civ:1, 8cku:1, 8cmj:1, 5dat:D5, 5dat:d5, 5dc3:D5, 5dc3:d5, 5dge:D5, 5dge:d5, 5dgf:D5, 5dgf:d5, 5dgv:D5, 5dgv:d5, 6eml:K, 8eub:BZ, 8evp:BZ, 8evq:BZ, 8evr:BZ, 8evs:BZ, 8evt:BZ, 8ewb:BZ, 8ewc:BZ, 6fai:Z, 5fci:D5, 5fci:d5, 5fcj:D5, 5fcj:d5, 6gq1:AP, 6gqb:AP, 6gqv:AP, 6hhq:a, 6hhq:d5, 5i4l:D5, 5i4l:d5, 6i7o:K, 6i7o:Kb, 3j6x:25, 3j6y:25, 3j77:25, 3j78:25, 5juo:WB, 5jup:WB, 5jus:WB, 5jut:WB, 5juu:WB, 8k2d:SZ, 8k82:SZ, 5lyb:D5, 5lyb:d5, 5m1j:Z2, 5mc6:K, 5mei:d5, 5mei:a, 7mpi:BZ, 7mpj:BZ, 7n8b:BZ, 5ndg:D5, 5ndg:d5, 5ndv:D5, 5ndv:d5, 5ndw:D5, 5ndw:d5, 7nrc:SK, 7nrd:SK, 5obm:D5, 5obm:d5, 5on6:d5, 5on6:a, 7osa:eS25, 7osm:eS25, 6q8y:K, 6rbd:Z, 6rbe:Z, 6s47:Ba, 6snt:Z, 6sv4:K, 6sv4:Kb, 6sv4:Kc, 6t4q:SZ, 6t7i:SZ, 6t7t:SZ, 6t83:Zb, 6t83:0, 5tbw:a, 5tbw:d5, 6tb3:K, 5tga:D5, 5tga:d5, 5tgm:D5, 5tgm:d5, 6tnu:K, 4u3m:D5, 4u3m:d5, 4u3n:D5, 4u3n:d5, 4u3u:D5, 4u3u:d5, 4u4n:D5, 4u4n:d5, 4u4o:D5, 4u4o:d5, 4u4q:D5, 4u4q:d5, 4u4r:D5, 4u4r:d5, 4u4u:D5, 4u4u:d5, 4u4y:D5, 4u4y:d5, 4u4z:D5, 4u4z:d5, 4u50:D5, 4u50:d5, 4u51:D5, 4u51:d5, 4u52:D5, 4u52:d5, 4u53:D5, 4u53:d5, 4u55:D5, 4u55:d5, 4u56:D5, 4u56:d5, 4u6f:D5, 4u6f:d5, 4uer:8, 4v6i:AV, 4v88:AZ, 4v88:CZ, 4v8y:AZ, 4v8z:AZ, 4v92:BZ, 6wdr:Z, 6woo:ZZ, 6xiq:AP, 6xir:AP, 8y0u:SZ, 6y7c:Z, 6z6j:SZ, 6z6k:SZ, 6zce:a, 7zpq:AZ, 6zqg:DZ, 7zrs:AZ, 6zu9:M, 7zuw:AZ, 7zux:DZ, 6zvi:J, 7zw0:sK
3 8c3a:b 72 71 0.7051 0.7639 0.7746 3.18e-37 8c3a:DM, 8cq7:b, 8cq7:DM, 8cqw:b, 8cqw:DM, 8cre:b, 8cre:DM, 8oeq:b, 8oeq:DM, 7pzy:a, 7q08:a, 7q0f:a, 7q0p:a, 7q0r:a
4 7r81:a2 71 70 0.4872 0.5352 0.5429 7.74e-21 7olc:SZ, 7old:SZ, 8oo0:SZ, 7z3n:SZ, 7z3o:SZ
5 7qiy:P 75 73 0.4359 0.4533 0.4658 3.34e-20 8auv:I, 8b2l:I1, 7qiz:ZA
6 8ip8:ta 77 74 0.4231 0.4286 0.4459 2.24e-19 8ip9:ta, 8ipa:ta, 8ipb:ta, 8jiw:BZ, 8r57:Z
7 5aj0:BZ 86 73 0.4231 0.3837 0.4521 1.45e-18 7a01:M3, 7a09:P, 5a2q:Z, 9bdl:AS25, 9bdn:AS25, 9bdp:AS25, 8bhf:a3, 9bkd:e, 9bln:e, 8btk:Ay, 7cpu:SZ, 7cpv:SZ, 4d5l:Z, 4d61:Z, 6d90:aa, 6d9j:aa, 9f1b:Ay, 9f1c:Ay, 9f1d:Ay, 6fec:W, 5flx:Z, 6g18:Z, 6g4s:Z, 6g4w:Z, 6g51:Z, 6g53:Z, 6g5h:Z, 6g5i:Z, 8g5y:SZ, 8g5z:SZ, 8g60:SZ, 8g61:SZ, 8g6j:SZ, 8glp:SZ, 6gz3:BZ, 6gz4:BZ, 6gz5:BZ, 6hcf:a1, 6hcm:a1, 8ifd:3O, 8ife:3O, 6ip5:3O, 6ip6:3O, 6ip8:3O, 3j7p:SZ, 3j7r:SZ, 3jag:ZZ, 3jah:ZZ, 3jai:ZZ, 3jaj:SZ, 3jan:SZ, 8jdj:AL, 8jdk:AL, 8jdl:AL, 8jdm:AL, 7jqb:a, 7jqc:a, 5k0y:W, 8k2c:SZ, 7k5i:Z, 4kzx:Z, 4kzy:Z, 4kzz:Z, 5lks:SZ, 7ls1:R3, 7ls2:R3, 5lzs:ZZ, 5lzt:ZZ, 5lzu:ZZ, 5lzv:ZZ, 5lzw:ZZ, 5lzx:ZZ, 5lzy:ZZ, 5lzz:ZZ, 7mdz:ZZ, 6mtb:ZZ, 6mtc:ZZ, 6mtd:ZZ, 6mte:ZZ, 7nwg:a2, 7nwh:ZZ, 7nwi:ZZ, 7o7y:Ay, 7o7z:Ay, 7o80:Ay, 7o81:Ay, 5oa3:Z, 6ole:SZ, 6olf:SZ, 6olg:BZ, 6oli:SZ, 6olz:BZ, 6om0:SZ, 6om7:SZ, 7oya:Z2, 7oyb:Z2, 7oyc:Z2, 7oyd:ZZ, 8oz0:m, 8p03:n, 8p09:n, 8p2k:Ay, 6p4g:a, 6p4h:a, 6p5i:a, 6p5j:a, 6p5k:a, 6p5n:a, 8pj1:e, 8pj2:e, 8pj3:e, 8pj4:e, 8pj5:e, 8pj6:e, 8ppk:Z, 8ppl:AZ, 8q7z:Ay, 8q87:Ay, 7qgg:SZ, 8qoi:SZ, 7qp6:e, 7qp7:e, 7qvp:SZ, 7qvp:RZ, 6qzp:SZ, 7r4x:Z, 6r5q:OO, 6r6g:OO, 6r6p:OO, 6r7q:OO, 8scb:ZZ, 6sgc:a1, 7syg:a, 7syh:a, 7syi:a, 7syj:a, 7syk:a, 7syl:a, 7sym:a, 7syn:a, 7syo:a, 7syp:a, 7syq:a, 7syr:a, 7sys:a, 7syt:a, 7syu:a, 7syv:a, 7syw:a, 7syx:a, 5t2c:AR, 8t4s:Z, 7toq:AS25, 7tor:AS25, 7tql:a, 7ucj:ZZ, 7uck:ZZ, 4ug0:SZ, 4ujc:CZ, 4ujd:CZ, 4uje:BZ, 4v6x:AZ, 5vyc:Z1, 5vyc:Z2, 5vyc:Z5, 5vyc:Z3, 5vyc:Z4, 5vyc:Z6, 6w2s:a, 6w2t:i, 7wtt:Z, 7wtu:Z, 7wtv:Z, 7wtw:Z, 7wtx:Z, 7wtz:Z, 7wu0:Z, 6xa1:SZ, 7xnx:SZ, 7xny:SZ, 8xsx:SZ, 8xsy:SZ, 8xsz:SZ, 8xxl:SZ, 8xxm:SZ, 8xxn:SZ, 6y0g:SZ, 8y0w:SZ, 8y0x:SZ, 6y2l:SZ, 6y57:SZ, 6yal:n, 6yam:n, 6yan:h, 6ybs:e, 8yoo:SZ, 8yop:SZ, 6z6l:SZ, 6z6m:SZ, 6z6n:SZ, 7zjw:Sk, 7zjx:Sk, 6zlw:a, 6zm7:SZ, 6zme:SZ, 6zmi:SZ, 6zmo:SZ, 6zmt:a, 6zmw:e, 6zn5:a, 6zoj:Z, 6zol:Z, 6zon:P, 6zp4:P, 6zuo:Z, 6zv6:Z, 6zvh:Z, 6zvj:P, 6zvk:M3, 6zxd:Z, 6zxe:Z, 6zxf:Z, 6zxg:Z, 6zxh:Z
8 4v3p:SV 100 72 0.4103 0.3200 0.4444 2.10e-18 4v7e:BZ
9 6zj3:Sa 78 77 0.4359 0.4359 0.4416 3.41e-17
10 4v6w:AZ 74 73 0.3974 0.4189 0.4247 2.14e-16 6xu6:AZ, 6xu7:AZ, 6xu8:AZ
11 4v8m:AU 85 77 0.3846 0.3529 0.3896 3.06e-15 8ova:AU, 8ove:AU
12 9bh5:AZ 71 71 0.3590 0.3944 0.3944 1.38e-14 9cai:AZ
13 5xxu:Z 71 70 0.3333 0.3662 0.3714 1.50e-12
14 8rxh:Sa 105 76 0.3333 0.2476 0.3421 1.92e-12 8a3w:Sa, 8a98:Sa, 6az1:a, 8ovj:Sa, 8rxx:Sa
15 7ase:a 70 67 0.3205 0.3571 0.3731 9.49e-12 5opt:a
16 4v5o:A8 93 70 0.2564 0.2151 0.2857 3.38e-07 4bts:A8, 4bts:B8, 4bts:C8, 4bts:D8, 4v5o:B8
17 7qca:SZ0 76 60 0.2436 0.2500 0.3167 3.60e-05
18 7qep:D5 87 69 0.2308 0.2069 0.2609 7.28e-05
19 6zu5:SZ0 72 71 0.2179 0.2361 0.2394 1.91e-04
20 5xyi:Z 73 59 0.2436 0.2603 0.3220 2.34e-04
21 8t50:C 474 61 0.2051 0.0338 0.2623 0.015 8t50:B, 8t50:A, 8t50:D
22 6rm3:SZ0 91 68 0.2308 0.1978 0.2647 0.44
23 8t4m:D 533 71 0.2308 0.0338 0.2535 0.67 9bc6:D, 9bc6:A, 9bc6:B, 9bc6:C, 9bc7:A, 9bc7:B, 9bc7:C, 9bc7:D, 3bpz:A, 3bpz:B, 3bpz:C, 3bpz:D, 5khg:A, 5khh:A, 5khi:A, 5khj:A, 5khj:B, 5khk:A, 2q0a:A, 2q0a:B, 1q3e:A, 1q3e:B, 1q43:A, 1q43:B, 1q5o:A, 8t4m:C, 8t4m:B, 8t4m:A, 8t4y:A, 8t4y:D, 8t4y:C, 8t4y:B, 3u0z:A, 3u0z:B, 3u10:A, 5u6p:A, 5u6p:B, 5u6p:C, 5u6p:D, 8uc7:D, 8uc7:A, 8uc7:B, 8uc7:C, 6uqf:A, 6uqf:B, 6uqf:C, 6uqf:D, 6uqg:A, 6uqg:B, 6uqg:C, 6uqg:D
24 3pju:A 249 38 0.1538 0.0482 0.3158 5.8 3pjt:A, 3pjt:B
25 7quj:A 259 22 0.1154 0.0347 0.4091 6.4 7quj:B, 7quj:C, 7quj:D
26 8kdb:A 2117 43 0.1923 0.0071 0.3488 7.5 8kdc:A
27 1qp8:A 301 23 0.1410 0.0365 0.4783 8.3 1qp8:B
28 1i1q:A 512 41 0.1538 0.0234 0.2927 8.3
29 3lnn:A 341 32 0.1410 0.0323 0.3438 8.5
30 6s6z:A 1083 41 0.1795 0.0129 0.3415 8.5 6s6z:D, 6s6z:B, 6s6z:H, 6s6z:F, 6s6z:G, 6s6z:E, 6s6z:C, 6sd0:A, 6sd0:B, 6sd0:C, 6sd0:D
31 9bh5:CN 203 52 0.2308 0.0887 0.3462 9.2 9cai:CN

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218