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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
SIPSYLHADDLGPWGNYLQQVDRVAPYLGSLSRWIETLKRPKRILIVDVPIELDNGTVAHFEGYRVQHNVSRGPGKGGVR
YHQDVTLSEVMALSAWMSVKNAAVNVPYGGAKGGIRVDPRKLSRGELERVTRRYTSEIGIIIGPNTDIPAPDVNTNEQIM
AWMMDTYSMNQGQTATGVVTGKPISLGGSLGRKEATGRGVFVVGCEAAKKKGVEIEGARIAVQGFGNVGGIAAKLFQEAG
AKVIAVQDHTGTIHQPAGVDTAKLLDHVGRTGGVAGFEGAEPMPNDEFWTVETEILIPAALENQITEKNASKIRTKIIVE
GANGPTTTAADDILSANGVLVIPDVIANAGGVTVSYFEWVQTEDEINHRLERVMREAFAGVWAVAEEHKVSVRTAAFIVA
CKRILMAREMRGLYP

The query sequence (length=415) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4xgi:A 416 416 1.0000 0.9976 0.9976 0.0 4xgi:B, 4xgi:C, 4xgi:D, 4xgi:E, 4xgi:F
2 3aoe:B 424 419 0.6771 0.6627 0.6706 0.0 3aoe:A, 3aog:A, 3aog:E, 3aog:B, 3aog:D, 3aog:C, 3aog:F, 3aog:G, 3aog:I, 3aog:H, 3aog:J, 3aog:L, 3aog:K
3 8xd5:A 419 413 0.4771 0.4726 0.4794 2.34e-127 8hho:A, 8hiq:A, 8hiz:A, 8hj9:A, 8xco:A, 8xcp:A, 8xcq:A, 8xcr:A, 8xcs:A, 8xct:A, 8xcu:A, 8xcv:A, 8xcw:A, 8xcx:A, 8xcy:A, 8xcz:A, 8xd0:A, 8xd1:A, 8xd2:A, 8xd3:A, 8xd4:A, 8xd6:A, 8znb:A, 8znc:A, 8znd:A, 8zne:A, 8zng:A
4 8owm:C 413 392 0.4386 0.4407 0.4643 8.45e-117 8owm:A, 8owm:B, 8owm:D, 8owm:E, 8owm:F, 8own:A, 8own:B, 8own:C, 8own:D, 8own:E, 8own:F
5 6yeh:A 410 396 0.4506 0.4561 0.4722 3.39e-116 6yeh:B, 6yeh:C, 6yeh:D, 6yeh:E, 6yeh:F, 6yei:A, 6yei:B, 6yei:C, 6yei:D, 6yei:E, 6yei:F
6 8s38:B 414 401 0.4265 0.4275 0.4414 5.72e-112 8s38:A, 8s38:C, 8s39:A, 8s39:B, 8s39:C, 8s3a:A, 8s3a:B, 8s3a:C, 8s3a:D, 8s3a:E, 8s3a:F, 8s3b:A, 8s3b:B, 8s3b:C, 8s3b:D, 8s3b:E, 8s3b:F, 8s3b:G, 8s3b:H, 8s3b:I, 8s3b:J, 8s3b:K, 8s3b:L, 8s3c:B, 8s3d:A, 8s3d:B, 8s3d:C, 8s3d:D, 8s3d:E, 8s3d:F
7 8kar:A 414 405 0.4169 0.4179 0.4272 1.43e-102 8kao:C, 8kar:B, 8kar:C
8 1v9l:A 418 391 0.4289 0.4258 0.4552 1.96e-102 1v9l:B, 1v9l:C, 1v9l:D, 1v9l:E, 1v9l:F
9 3aoe:F 417 421 0.3952 0.3933 0.3895 2.06e-99 3aoe:E, 3aoe:C, 3aoe:D
10 6dhd:A 501 348 0.3590 0.2974 0.4282 4.28e-87 8ar7:A, 8ar7:B, 8ar7:C, 8ar7:E, 8ar7:D, 8ar7:F, 8ar8:A, 8ar8:B, 8ar8:C, 8ar8:D, 8ar8:E, 8ar8:F, 6dhd:B, 6dhd:C, 6dhd:D, 6dhd:F, 6dhd:E, 6dhk:A, 6dhk:B, 6dhk:F, 6dhk:C, 6dhk:D, 6dhk:E, 6dhk:G, 6dhk:H, 6dhk:L, 6dhk:I, 6dhk:J, 6dhk:K, 6dhl:A, 6dhl:F, 6dhl:B, 6dhl:C, 6dhl:D, 6dhl:E, 6dhl:G, 6dhl:L, 6dhl:H, 6dhl:I, 6dhl:J, 6dhl:K, 6dhm:A, 6dhm:B, 6dhm:C, 6dhm:D, 6dhm:E, 6dhm:F, 6dhn:A, 6dhn:B, 6dhn:C, 6dhn:D, 6dhn:E, 6dhn:F, 6dhq:A, 6dhq:B, 6dhq:C, 6dhq:D, 6dhq:E, 6dhq:F, 3etd:A, 3etd:E, 3etd:B, 3etd:C, 3etd:D, 3etd:F, 3ete:A, 3ete:E, 3ete:B, 3ete:C, 3ete:F, 3ete:D, 3etg:A, 3etg:B, 3etg:C, 3etg:D, 3etg:E, 3etg:F, 1hwy:A, 1hwy:B, 1hwy:F, 1hwy:C, 1hwy:E, 1hwy:D, 3jd0:A, 3jd0:B, 3jd0:C, 3jd0:D, 3jd0:E, 3jd0:F, 3jd1:A, 3jd1:C, 3jd1:B, 3jd1:D, 3jd1:F, 3jd1:E, 3jd2:A, 3jd2:B, 3jd2:C, 3jd2:D, 3jd2:E, 3jd2:F, 3jd3:A, 3jd3:B, 3jd3:C, 3jd3:D, 3jd3:E, 3jd3:F, 3jd4:A, 3jd4:C, 3jd4:B, 3jd4:D, 3jd4:F, 3jd4:E, 1nqt:A, 1nqt:B, 1nqt:F, 1nqt:C, 1nqt:D, 1nqt:E, 1nqt:G, 1nqt:H, 1nqt:L, 1nqt:I, 1nqt:J, 1nqt:K
11 1bgv:A 449 400 0.3205 0.2962 0.3325 1.54e-53
12 5gud:E 460 396 0.3229 0.2913 0.3384 9.34e-52 5gud:A, 5gud:B, 5gud:C, 5gud:D, 5gud:F, 5ijz:A, 5ijz:B, 5ijz:C, 5ijz:D, 5ijz:E, 5ijz:F, 5ijz:G, 5ijz:H, 5ijz:J
13 7f79:C 458 383 0.2867 0.2598 0.3107 1.52e-38 7f79:A, 7f79:B, 7f79:D, 7f79:E, 7f79:F
14 5xvv:B 459 385 0.2988 0.2702 0.3221 4.08e-36 5xvv:A, 5xvv:C, 5xvx:A, 5xw0:A, 5xwc:A
15 7ecr:A 460 385 0.2916 0.2630 0.3143 4.54e-35 7ecr:B, 7ecr:C, 7ecs:A, 7ecs:B, 7ecs:C, 7ect:A, 7ect:B, 7ect:C
16 1bw9:A 350 368 0.2482 0.2943 0.2799 4.50e-19 1bw9:B, 1bxg:A, 1bxg:B, 1c1d:A, 1c1d:B, 1c1x:A, 1c1x:B
17 8gxd:A 366 352 0.2386 0.2705 0.2812 5.25e-18
18 6ach:A 364 365 0.2482 0.2830 0.2822 1.32e-17 6ach:B, 6ach:C, 6ach:D, 6ach:E, 6ach:F, 6ach:G, 6ach:H
19 8hr6:A 359 363 0.2410 0.2786 0.2755 2.66e-17 8hr6:B
20 1dxy:A 330 34 0.0386 0.0485 0.4706 1.0
21 5t5q:C 245 59 0.0530 0.0898 0.3729 2.6 5t5q:A, 5t5q:B, 5t5q:D
22 6itd:A 328 45 0.0410 0.0518 0.3778 3.4 6k36:A, 6k37:A, 6k38:A
23 2vyn:D 334 30 0.0241 0.0299 0.3333 3.6 2vyv:D
24 4a0g:A 769 71 0.0482 0.0260 0.2817 4.1 4a0f:B, 4a0g:B, 4a0h:A, 4a0h:B, 4a0r:A, 4a0r:B
25 7vh6:A 768 87 0.0530 0.0286 0.2529 4.2 7vh6:B, 7vh6:C, 7vh6:D, 7vh6:E, 7vh6:F
26 4a0f:A 746 67 0.0458 0.0255 0.2836 4.4
27 4a0g:D 709 67 0.0458 0.0268 0.2836 4.7
28 3l9w:B 357 47 0.0313 0.0364 0.2766 5.2 3eyw:A, 3eyw:B, 3l9w:A
29 1dss:G 333 31 0.0289 0.0360 0.3871 5.7 1dss:R, 1gpd:G, 1gpd:R, 1ihx:A, 1ihx:B, 1ihx:C, 1ihx:D, 1ihy:A, 1ihy:B, 1ihy:C, 1ihy:D, 1szj:G, 1szj:R
30 3h9e:P 337 29 0.0265 0.0326 0.3793 7.6 5c7o:O, 5c7o:P, 3h9e:O, 3pfw:O, 3pfw:P
31 3gg2:A 431 36 0.0361 0.0348 0.4167 8.2 3gg2:D, 3gg2:B, 3gg2:C

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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