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●TM-score ●TM-align ●US-align ●MM-align ●RNA-align ●NW-align ●LS-align ●EDTSurf ●MVP ●MVP-Fit ●SPICKER ●HAAD ●PSSpred ●3DRobot ●MR-REX ●I-TASSER-MR ●SVMSEQ ●NeBcon ●ResPRE ●TripletRes ●DeepPotential ●WDL-RF ●ATPbind ●DockRMSD ●DeepMSA ●FASPR ●EM-Refiner ●GPU-I-TASSER

●BioLiP ●E. coli ●GLASS ●GPCR-HGmod ●GPCR-RD ●GPCR-EXP ●Tara-3D ●TM-fold ●DECOYS ●POTENTIAL ●RW/RWplus ●EvoEF ●HPSF ●THE-DB ●ADDRESS ●Alpaca-Antibody ●CASP7 ●CASP8 ●CASP9 ●CASP10 ●CASP11 ●CASP12 ●CASP13 ●CASP14

BioLiP
>protein
SIGAKLALVIKSGKVVLGYRSTLKALRSGKAKLILIAANTPPLRKSELEYYSMMSKTPVHHYSGTNIELGTACGKLFRCS
TMAILDAGDSDILAD

The query sequence (length=95) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length 		Aligned
length 		Identity
(normalized by query) 		Identity
(normalized by hit) 		Identity (normalized
by aligned length) 		E-value Homologs
to hit
1 8i9x:Lc 98 95 1.0000 0.9694 1.0000 1.09e-65 8i9y:Lc, 8i9z:Lc, 8ia0:Lc, 7olc:Lc, 7old:Lc, 8oo0:Lc, 8pv1:Lc, 8pv2:Lc, 8pv3:Lc, 8pv4:Lc, 8pv5:Lc, 8pv6:Lc, 8pv7:Lc, 8pv8:Lc, 8pvk:Lc, 8pvl:Lc, 7r81:e1, 7z3n:Lc, 7z3o:Lc
2 8etc:c 97 94 0.7579 0.7423 0.7660 1.41e-49 8esq:c, 8esr:c, 8eug:c, 8eui:c
3 8c3a:AD 96 94 0.6947 0.6875 0.7021 9.35e-46 8c3a:BX, 8cq7:AD, 8cq7:BX, 8cqw:AD, 8cqw:BX, 8cre:AD, 8cre:BX, 8oeq:AD, 8oeq:BX, 7pzy:AD, 7q08:AD, 7q0f:AD, 7q0p:AD, 7q0r:AD, 8q5i:AD
4 4v6w:Cc 100 93 0.6947 0.6600 0.7097 2.04e-45 6xu6:Cc, 6xu7:Cc, 6xu8:Cc
5 9bh5:Cc 96 93 0.6421 0.6354 0.6559 2.48e-45 9cai:Cc
6 4v6i:Bf 105 93 0.6947 0.6286 0.7097 1.03e-43 8aaf:P, 8agt:P, 8agu:P, 8agv:P, 8agw:P, 8agx:P, 8agz:P, 5apn:c, 5apo:c, 7b7d:LY, 8bip:Lc, 8bjq:Lc, 8bn3:O0, 8bqd:AY, 8bqx:AY, 7bt6:c, 7btb:c, 6cb1:c, 8ccs:O, 8cdl:O, 8cdr:O, 8ceh:O, 8cf5:O, 8cg8:O, 8cgn:O, 8civ:O, 8cku:O, 8cmj:O, 5dat:O0, 5dat:o0, 5dc3:O0, 5dc3:o0, 5dge:O0, 5dge:o0, 5dgf:O0, 5dgf:o0, 5dgv:O0, 5dgv:o0, 6elz:c, 6em5:c, 8eub:Ac, 8evp:Ac, 8evq:Ac, 8evr:Ac, 8evs:Ac, 8evt:Ac, 8ewb:Ac, 8ewc:Ac, 5fci:O0, 5fci:o0, 5fcj:O0, 5fcj:o0, 6ft6:c, 5gak:e, 6gq1:c, 6gqb:c, 6gqv:c, 5h4p:c, 6hd7:e, 8hfr:cC, 6hhq:AD, 6hhq:DE, 5i4l:O0, 5i4l:o0, 6i7o:AY, 6i7o:XY, 5it7:cc, 3j6x:70, 3j6y:70, 3j77:80, 3j78:80, 3jct:c, 5jcs:c, 5juo:HA, 5jup:HA, 5jus:HA, 5jut:HA, 5juu:HA, 8k2d:Lc, 8k82:Lc, 5lyb:O0, 5lyb:o0, 5m1j:c5, 6m62:c, 5mc6:AY, 5mei:AD, 5mei:DE, 7mpi:Ac, 7mpj:Ac, 6n8j:c, 6n8k:c, 6n8l:c, 6n8m:p, 6n8n:p, 6n8o:p, 7n8b:Ac, 7nac:c, 7nad:c, 5ndg:O0, 5ndg:o0, 5ndv:O0, 5ndv:o0, 5ndw:O0, 5ndw:o0, 7nrc:Le, 7nrd:Le, 5obm:O0, 5obm:o0, 7of1:c, 7oh3:c, 7ohq:c, 7ohr:c, 6oig:c, 5on6:AD, 5on6:DE, 7osa:eL30, 7osm:eL30, 8p8m:RC, 8p8n:RC, 8p8u:RC, 8pfr:RC, 6q8y:AY, 6qik:c, 6qt0:c, 6qtz:c, 7r72:c, 7r7a:c, 6r84:e, 6r86:e, 6r87:e, 6ri5:c, 7rr5:Lc, 6rzz:c, 6s05:c, 6s47:Ae, 6snt:an, 6sv4:AY, 6sv4:XY, 6sv4:zY, 1t0k:B, 6t4q:Lc, 5t62:p, 5t6r:p, 6t7i:Lc, 6t7t:Lc, 6t83:cy, 6t83:N, 5tbw:AD, 5tbw:DE, 6tb3:AY, 5tga:O0, 5tga:o0, 5tgm:O0, 5tgm:o0, 6tnu:AY, 7too:AL30, 7top:AL30, 7u0h:c, 4u3m:O0, 4u3m:o0, 4u3n:O0, 4u3n:o0, 4u3u:O0, 4u3u:o0, 4u4n:O0, 4u4n:o0, 4u4o:O0, 4u4o:o0, 4u4q:O0, 4u4q:o0, 4u4r:O0, 4u4r:o0, 4u4u:O0, 4u4u:o0, 4u4y:O0, 4u4y:o0, 4u4z:O0, 4u4z:o0, 4u50:O0, 4u50:o0, 4u51:O0, 4u51:o0, 4u52:O0, 4u52:o0, 4u53:O0, 4u53:o0, 4u55:O0, 4u55:o0, 4u56:O0, 4u56:o0, 4u6f:O0, 4u6f:o0, 7ug6:7, 7uoo:c, 7uqb:c, 7uqz:c, 6uz7:Bc, 7v08:c, 4v7h:B2, 4v7r:BZ, 4v7r:DZ, 4v88:Bc, 4v88:Dc, 4v8t:c, 4v8y:Bc, 4v8z:Bc, 8v87:c, 4v91:c, 6woo:c, 6xiq:c, 6xir:c, 8y0u:Lc, 6ylg:n, 6ylh:n, 6ylx:c, 6yly:c, 7z34:c, 6z6j:Lc, 6z6k:Lc, 7zpq:Bb, 7zrs:Bb, 7zs5:Bd, 7zuw:Bb, 7zux:Eb, 7zw0:Lf
7 6zj3:Ls 97 93 0.6316 0.6186 0.6452 1.22e-43
8 4v5z:B6 113 93 0.6526 0.5487 0.6667 1.71e-43 7a01:13, 8a3d:W, 5aj0:Ac, 8b5l:c, 8b6c:c, 9bdl:AL30, 9bdn:AL30, 9bdp:AL30, 7bhp:Lc, 8bhf:P1, 8bpo:b2, 8btk:Bc, 7cpu:Lc, 7cpv:Lc, 4d5y:c, 4d67:c, 6d90:c, 6d9j:c, 9f1b:Bc, 9f1c:Bc, 9f1d:Bc, 7f5s:Lc, 8fky:LO, 8fkz:LO, 8fl2:LO, 8fl3:LO, 8fl4:LO, 8fl6:LO, 8fl7:LO, 8fl9:LO, 8fla:LO, 8flb:LO, 8flc:LO, 8fld:LO, 8fle:LO, 8flf:LO, 6frk:c, 6ftg:c, 6fti:c, 6ftj:c, 8g5y:Lc, 8g5z:Lc, 8g60:Lc, 8g61:Lc, 8g6j:Lc, 8glp:Lc, 6gz3:Ac, 6gz4:Ac, 6gz5:Ac, 6hcf:c3, 6hcj:c3, 6hcm:c3, 6hcq:c3, 8idt:E, 8idy:E, 8ie3:E, 8ifd:2W, 8ife:2W, 8ine:E, 8inf:E, 8ink:E, 6ip5:2W, 6ip6:2W, 6ip8:2W, 8ipd:E, 8ipx:E, 8ipy:E, 8ir1:E, 8ir3:E, 3j7o:c, 3j7p:c, 3j7q:c, 3j7r:c, 3j92:c, 3jag:c, 3jah:c, 3jai:c, 3jaj:c, 3jan:c, 8jdj:h, 8jdk:h, 8jdl:h, 8jdm:h, 8k2c:Lc, 5lks:Lc, 6lqm:E, 6lsr:E, 6lss:E, 7ls1:W2, 7ls2:W2, 6lu8:E, 5lzs:c, 5lzt:c, 5lzu:c, 5lzv:c, 5lzw:c, 5lzx:c, 5lzy:c, 5lzz:c, 7mdz:c, 6mtb:c, 6mtc:c, 6mtd:c, 6mte:c, 7nfx:c, 7nwg:c3, 7nwh:c, 7nwi:c, 7o7y:Bc, 7o7z:Bc, 7o80:Bc, 7o81:Bc, 7obr:c, 8ohd:Lc, 8oj0:Lc, 8oj5:Lc, 8oj8:Lc, 6ole:d, 6olf:d, 6olg:Ac, 6oli:d, 6olz:Ac, 6om0:d, 6om7:d, 7ow7:W, 7oya:c1, 7oyb:c1, 7oyc:c1, 7oyd:c, 8p2k:Bc, 6p5i:Ac, 6p5j:Ac, 6p5k:Ac, 6p5n:Ac, 8q7z:Bc, 8q87:Bc, 8qfd:c, 7qgg:d, 8qoi:Lc, 7qvp:Lc, 7qvp:Mc, 7qwq:c, 7qwr:c, 7qws:c, 6qzp:Lc, 6r5q:c, 6r6g:c, 6r6p:c, 6r7q:c, 8rjb:c, 8rjc:c, 8rjd:c, 8scb:c, 6sgc:c2, 6swa:a, 5t2c:W, 6t59:c3, 7tm3:c, 7toq:AL30, 7tor:AL30, 7tut:c, 7ucj:c, 7uck:c, 4ug0:Lc, 4ujc:Bc, 4ujd:Ac, 4uje:Cc, 4v6x:Cc, 6w6l:d, 6xa1:Lc, 7xnx:Lc, 7xny:Lc, 8xsx:Lc, 8xsy:Lc, 8xsz:Lc, 6y0g:Lc, 8y0w:Lc, 8y0x:Lc, 6y2l:Lc, 6y57:Lc, 6y6x:Lc, 8yoo:Lc, 8yop:Lc, 6z6l:Lc, 6z6m:Lc, 6z6n:Lc, 7zjw:Lf, 7zjx:Lf, 6zm7:Lc, 6zme:Lc, 6zmi:Lc, 6zmo:Lc, 6zvk:13
9 4v8p:AG 96 93 0.6211 0.6146 0.6344 6.60e-43 4v8p:DG, 4v8p:FG, 4v8p:HG
10 8azw:P 97 93 0.6211 0.6082 0.6344 5.77e-41 8b2l:P3, 7qiw:e, 7qiz:e
11 4v8m:Bg 96 92 0.5684 0.5625 0.5870 6.18e-40 8ova:Bg, 8ove:Bg
12 8rxh:Ld 97 92 0.5579 0.5464 0.5761 1.78e-38 8a3w:d, 8a98:d, 6az3:d, 8ovj:d, 8rxx:Ld, 5t2a:e
13 5xxb:b 96 92 0.6211 0.6146 0.6413 7.87e-38
14 3j79:6 98 93 0.5579 0.5408 0.5699 3.54e-35 3jbn:A6, 3jbo:A6, 3jbp:A6, 8tpu:A6, 5umd:6
15 4v3p:Lf 112 88 0.5263 0.4464 0.5682 8.75e-33 8ip8:RA, 8ipa:RA, 8ipb:RA, 8jiv:Cc, 4v7e:Cc, 1ysh:C
16 8br8:Ld 107 92 0.4632 0.4112 0.4783 1.56e-26 8brm:Ld, 8bsi:Ld, 8bsj:Ld, 8btd:Ld, 8btr:Ld, 8fru:c, 7pwg:c, 7pwo:c2
17 5xy3:c 96 93 0.4842 0.4792 0.4946 1.91e-25
18 3jcs:d 75 88 0.4211 0.5333 0.4545 1.03e-23
19 8p5d:LCC 99 90 0.3895 0.3737 0.4111 3.26e-23 8p60:LCC, 8p60:KCC, 7qca:LCC
20 5t5h:g 66 59 0.3684 0.5303 0.5932 5.64e-23
21 4v4n:AZ 99 85 0.4000 0.3838 0.4471 1.98e-22 4v6u:BZ
22 8hku:L30E 94 90 0.3789 0.3830 0.4000 4.89e-19 8hkv:L30E, 8hky:L30E, 8hkz:L30E, 8hl1:L30E, 8hl2:L30E, 8hl3:L30E, 8hl4:L30E, 8hl5:L30E
23 6skf:Bb 96 90 0.3684 0.3646 0.3889 1.75e-18 6skg:Bb, 6th6:Bb
24 6rm3:LCC 104 95 0.3474 0.3173 0.3474 1.47e-17
25 6zu5:LCC 100 90 0.3579 0.3400 0.3778 4.76e-17
26 7qep:O0 90 90 0.2842 0.3000 0.3000 7.59e-12
27 5gin:C 122 86 0.3053 0.2377 0.3372 1.41e-06 5gin:D, 5gin:L, 5gio:C, 5gio:D, 5gio:L, 5gip:C, 5gip:D, 5gip:M, 5gip:N, 3id5:C, 3id5:G, 5jpq:U, 5jpq:V, 3pla:C, 3pla:D, 3pla:L
28 8hku:L7A1 123 85 0.2842 0.2195 0.3176 7.18e-06 8hku:L7A2, 8hkv:L7A1, 8hkv:L7A2, 8hkx:SL7A, 8hky:L7A1, 8hky:L7A2, 8hky:SL7A, 8hkz:L7A1, 8hkz:L7A2, 8hkz:SL7A, 8hl1:SL7A, 8hl1:L7A1, 8hl1:L7A2, 8hl2:L7A1, 8hl2:L7A2, 8hl2:SL7A, 8hl3:L7A1, 8hl3:L7A2, 8hl3:SL7A, 8hl4:L7A1, 8hl4:L7A2, 8hl4:SL7A, 8hl5:L7A1, 8hl5:L7A2, 8hl5:SL7A, 8wkp:SL7A, 8wq2:SL7A, 8wq4:SL7A
29 6q8u:C 122 85 0.3053 0.2377 0.3412 6.14e-05 4bw0:B, 4c4w:C, 4c4w:G, 5fj4:C, 5fj4:G, 5g4u:C, 5g4u:D, 5g4u:G, 5g4u:H, 5g4u:K, 5g4u:L, 5g4v:C, 5g4v:D, 5g4v:G, 5g4v:H, 6hct:C, 6hct:D, 6hct:G, 6q8u:D, 1rlg:A, 1rlg:B
30 6k0a:I 116 89 0.2947 0.2414 0.3146 6.54e-05 6k0a:J, 6k0b:I, 6k0b:J, 1sds:A, 1sds:C, 1sds:B
31 6tmf:b 123 87 0.2947 0.2276 0.3218 2.54e-04
32 4lck:A 81 75 0.2211 0.2593 0.2800 0.009 4lck:D, 4tzp:A, 4tzp:D, 4tzv:A, 4tzw:A, 4tzz:A, 4tzz:D, 4tzz:G, 4tzz:J, 3v7e:A, 3v7e:B
33 5y7m:A 125 94 0.3053 0.2320 0.3085 0.010 4by9:G, 4by9:J, 4by9:D, 4by9:M, 5dcv:A, 5dcv:C, 3hax:D, 3hay:D, 3hjw:C, 2hvy:D, 5jb3:3, 5jbh:3, 3lwo:C, 3lwp:C, 3lwq:C, 3lwr:C, 3lwv:C, 3nmu:G, 3nmu:C, 3nvi:B, 3nvi:D, 3nvk:E, 3nvk:H, 7ozq:B, 7ozq:D, 7ozq:C, 7ozq:A, 6skf:BH, 6skf:BI, 6skg:BH, 6skg:BI, 6sw9:3, 6swc:3, 6swe:3, 6th6:BH, 6th6:BI, 6tph:A, 4v4n:B3, 4v4n:AG, 4v6u:A3, 4v6u:BG, 4v6u:B4, 5xtm:A, 5xtm:C, 5y7m:C, 7zag:3, 7zah:3, 7zai:3, 7zhg:3
34 5xyi:M 103 30 0.1474 0.1359 0.4667 0.071
35 3cc2:F 119 87 0.2211 0.1765 0.2414 0.28 3cc4:F, 3cc7:F, 3cce:F, 3ccj:F, 3ccl:F, 3ccm:F, 3ccq:F, 3ccr:F, 3ccs:F, 3ccu:F, 3ccv:F, 3cd6:F, 3cma:F, 3cme:F, 3cpw:F, 3cxc:F, 3g4s:F, 3g6e:F, 3g71:F, 3i55:F, 3i56:F, 1jj2:F, 1k73:H, 1k8a:H, 1k9m:H, 1kc8:H, 1kd1:H, 1kqs:F, 1m1k:H, 1m90:H, 1n8r:H, 1nji:H, 2otj:F, 2otl:F, 3ow2:F, 1q7y:H, 1q81:H, 1q82:H, 1q86:H, 2qa4:F, 2qex:F, 1qvf:F, 1qvg:F, 1s72:F, 4v9f:F, 1vq4:F, 1vq5:F, 1vq6:F, 1vq7:F, 1vq8:F, 1vq9:F, 1vqk:F, 1vql:F, 1vqm:F, 1vqn:F, 1vqo:F, 1vqp:F, 1w2b:F, 1yhq:F, 1yi2:F, 1yij:F, 1yit:F, 1yj9:F, 1yjn:F, 1yjw:F
36 6lx5:A 273 65 0.2000 0.0696 0.2923 0.39 5azt:A, 5azt:B, 4bcr:A, 4bcr:B, 7bpy:A, 7bpy:C, 7bpz:A, 7bpz:C, 7bq0:A, 7bq0:C, 7bq1:A, 7bq2:A, 7bq3:A, 7bq4:A, 7c6q:A, 4ci4:A, 7e5f:A, 7e5g:A, 7e5h:A, 7e5i:A, 3et1:A, 3et1:B, 3g8i:A, 8huk:A, 8huk:C, 8hun:A, 8huq:A, 5hyk:A, 1i7g:A, 1k7l:A, 1k7l:C, 1k7l:E, 1k7l:G, 6kax:A, 6kay:A, 6kaz:A, 6kb0:A, 6kb1:A, 6kb2:A, 6kb3:A, 6kb4:A, 6kb5:A, 6kb6:A, 6kb7:A, 6kb8:A, 6kb9:A, 6kba:A, 3kdt:A, 3kdt:B, 3kdu:A, 3kdu:B, 1kkq:A, 1kkq:B, 1kkq:C, 1kkq:D, 6kxx:A, 6kxy:A, 6kyp:A, 6kyp:B, 6l36:A, 6l36:B, 6l37:A, 6l37:B, 6l38:A, 6l38:B, 6l96:A, 6l96:B, 6lx4:A, 6lx4:B, 6lx5:B, 6lx6:A, 6lx7:A, 6lx8:A, 6lx9:A, 6lxa:A, 6lxb:A, 6lxc:A, 2npa:A, 2npa:C, 2p54:A, 2rew:A, 3sp6:A, 3vi8:A, 2znn:A
37 7ttn:E 528 37 0.1368 0.0246 0.3514 1.7 8i1u:B, 8i1u:J, 7nvl:B, 7nvl:b, 7nvm:B, 7nvm:b, 7nvn:B, 7nvn:b, 8sfe:b, 8sfe:B, 8sff:B, 8sff:b, 8sg8:B, 8sg8:b, 8sg9:B, 8sg9:b, 8sgc:B, 8sgc:b, 8sgl:B, 8sgl:b, 8sgq:B, 8sgq:b, 8sh9:B, 8sh9:b, 8sha:B, 8sha:b, 8shd:B, 8shd:b, 8she:B, 8she:b, 8shf:B, 8shf:b, 8shg:B, 8shg:b, 8shl:B, 8shl:b, 8shn:B, 8shn:b, 8sho:B, 8sho:b, 8shp:B, 8shp:b, 8shq:B, 8shq:b, 8sht:B, 8sht:b, 7trg:E, 7ttt:E, 7tub:E, 7x0s:B, 7x0s:L, 7x0v:B, 7x0v:L, 7x3j:B, 7x3j:b, 7x3u:b, 7x3u:B
38 1kno:E 214 40 0.1263 0.0561 0.3000 2.4 1kno:A, 1kno:C
39 3h4l:B 344 54 0.1895 0.0523 0.3333 2.7 3h4l:A
40 4d61:h 436 33 0.1158 0.0252 0.3333 5.2 5a8l:Q, 6d90:jj, 6hcf:j1, 6hcm:j1, 6ip8:zw, 3j5y:A, 3jag:ii, 3jah:ii, 3jai:ii, 5lzt:ii, 5lzu:ii, 5lzv:ii, 7nwh:ii, 7o80:By, 6p5n:Aq, 8scb:ii, 6zme:CH
41 3e1y:A 380 33 0.1158 0.0289 0.3333 5.9 3e1y:B, 6xa1:j
42 8tl0:I 479 25 0.1158 0.0230 0.4400 6.8 8tl0:A, 8tl0:D, 8tl0:B, 8tl0:C, 8tl0:L, 8tl0:K
43 8fru:G 197 35 0.1579 0.0761 0.4286 7.5 8br8:LI, 8brm:LI, 8bsi:LI, 8bsj:LI, 8btd:LI, 8btr:LI, 7pwg:G, 7pwo:G2
44 3cc2:K 132 36 0.0842 0.0606 0.2222 8.6 3cc4:K, 3cc7:K, 3cce:K, 3ccj:K, 3ccl:K, 3ccm:K, 3ccq:K, 3ccr:K, 3ccs:K, 3ccu:K, 3ccv:K, 3cd6:K, 3cma:K, 3cme:K, 3cpw:J, 3cxc:J, 1ffk:H, 3g4s:K, 3g6e:K, 3g71:K, 3i55:K, 3i56:K, 1jj2:J, 1k73:L, 1k8a:L, 1k9m:L, 1kc8:L, 1kd1:L, 1kqs:J, 1m1k:L, 1m90:L, 1n8r:L, 1nji:L, 2otj:K, 2otl:K, 3ow2:J, 1q7y:L, 1q81:L, 1q82:L, 1q86:L, 2qa4:K, 2qex:K, 1qvf:J, 1qvg:J, 1s72:K, 4v9f:K, 1vq4:K, 1vq5:K, 1vq6:K, 1vq7:K, 1vq8:K, 1vq9:K, 1vqk:K, 1vql:K, 1vqm:K, 1vqn:K, 1vqo:K, 1vqp:K, 1w2b:J, 1yhq:K, 1yi2:K, 1yij:K, 1yit:K, 1yj9:K, 1yjn:K, 1yjw:K
45 8ip8:bl 437 28 0.1158 0.0252 0.3929 10.0 8ipa:bl

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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