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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
SAPGTLSPDARNEKQPFYGEHQAGILTPQQAAMMLVAFDVLASDKADLERLFRLLTQRFAFLTQGGAAPETPNPRLPPLD
SGILGGYIAPDNLTITLSVGHSLFDERFGLAPQMPKKLQKMTRFPNDSLDAALCHGDVLLQICANTQDTVIHALRDIIKH
TPDLLSVRWKREGFISDHAARSKGKETPINLLGFKDGTANPDSQNDKLMQKVVWVTADQQEPAWTIGGSYQAVRLIQFRV
EFWDRTPLKEQQTIFGRDKQTGAPLGMQHEHDVPDYASDPEGKVIALDSHIRLANPRTAESESSLMLRRGYSYSLGVTNS
GQLDMGLLFVCYQHDLEKGFLTVQKRLNGEALEEYVKPIGGGYFFALPGVKDANDYFGSALLRV

The query sequence (length=384) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 2y4e:A 384 384 1.0000 1.0000 1.0000 0.0 3o72:A, 3o72:B, 3o72:C, 3o72:D, 2y4e:B, 2y4f:A, 2y4f:B
2 6jbn:A 391 376 0.6094 0.5985 0.6223 6.84e-169 6jbn:B
3 8rgs:A 366 370 0.3854 0.4044 0.4000 2.63e-84 4grc:A, 6i43:A, 6i43:B, 6i7c:A, 6i7c:B, 6i7z:A, 6i7z:B, 6i8e:A, 6i8e:B, 6i8i:A, 6i8i:B, 6i8j:A, 6i8j:B, 6i8k:A, 6i8k:B, 6i8o:A, 6i8o:B, 6i8p:A, 6i8p:B, 6i8q:A, 6i8q:B, 6i91:A, 6i91:B, 6ibn:A, 6ibn:B, 8olh:A, 8olh:B, 8olp:A, 8olp:B, 8omc:A, 8omc:B, 8pxp:A, 8pxp:B, 6q31:A, 6q31:B, 6q34:A, 6q34:B, 6q3d:A, 6q3d:B, 6q3e:A, 6q3e:B, 8rgs:B, 8rgw:A, 8rgw:B, 8rgy:A, 8rgy:B, 6tb8:A, 6tb8:B
4 7dlk:A 363 375 0.3750 0.3967 0.3840 9.56e-79 7dlk:B, 7dlk:C, 7dlk:D, 7dlk:E, 7dlk:F, 7e5q:A, 7e5q:B, 6kmm:A, 6kmm:B, 6kmm:C, 6kmm:D, 6kmm:E, 6kmm:F, 6kmn:A, 6kmn:B, 6kmn:C, 6kmn:D, 7pkx:A, 7pkx:B, 7pl0:A, 7pl0:B, 7pl0:C, 7pl0:D
5 8fjq:B 361 373 0.3802 0.4044 0.3914 1.11e-65 8fjq:A, 8fjr:A, 8fjr:B, 5jxu:A, 5jxu:B, 7rmu:A
6 6qzo:A 361 371 0.3594 0.3823 0.3720 8.46e-62 6qzo:B, 6qzo:C, 6qzo:D, 6qzo:E, 6qzo:F, 6qzo:G, 6qzo:H
7 4gt2:A 371 378 0.3307 0.3423 0.3360 4.36e-52 4gt2:B, 4gt2:E, 4gt2:G, 6gzw:A, 6gzw:B, 5map:A, 5map:B, 5mjh:A, 5mjh:B
8 4gs1:B 376 305 0.2812 0.2872 0.3541 1.10e-46 4gs1:A
9 8ck9:A 374 285 0.2734 0.2807 0.3684 3.66e-42
10 5fw4:A 368 370 0.2969 0.3098 0.3081 4.50e-39 5fw4:B
11 7anv:A 467 214 0.1536 0.1263 0.2757 2.46e-09
12 7ylo:A 311 329 0.2031 0.2508 0.2371 2.11e-07 7ylo:B
13 2iiz:A 306 142 0.1172 0.1471 0.3169 6.95e-07
14 5de0:B 298 236 0.1589 0.2047 0.2585 1.46e-06 5de0:A, 5de0:C, 5de0:D
15 7o9j:B 307 241 0.1641 0.2052 0.2614 1.29e-05 7o9j:A, 7o9l:A, 7o9l:B, 7odz:A, 7odz:B, 8ohy:A
16 7yzt:A 306 187 0.1250 0.1569 0.2567 1.81e-05 7yzt:B, 7yzt:C
17 8u4z:A 313 90 0.0781 0.0958 0.3333 5.13e-05
18 4gu7:A 310 182 0.1146 0.1419 0.2418 1.84e-04 4gu7:B, 4gu7:C, 4gu7:D, 8pws:A, 8pws:B, 8pws:C, 8pws:D, 8pws:E, 8pws:F, 8pwy:A, 8pwy:B, 8pwy:C, 8pwy:D, 8pwy:E, 8pwy:F, 7qze:A, 7qze:B, 7qze:C, 7qze:D, 7qze:E, 7qze:F, 7qzf:A, 7qzf:B, 7qzf:C, 7qzf:D, 7qzf:E, 7qzf:F, 7qzg:A, 7qzg:B, 7qzg:C, 7qzg:D, 7qzg:E, 7qzg:F, 7qzh:A, 7qzh:B, 7qzh:C, 7qzh:D, 7qzh:E, 7qzh:F, 8rwy:A, 8rwy:B, 8rwy:C, 8rwy:D, 8rwy:E, 8rwy:F, 6yr4:A, 6yr4:B, 6yr4:C, 6yr4:D, 6yr4:E, 6yr4:F, 6yrc:A, 6yrc:B, 6yrc:C, 6yrc:D, 6yrc:E, 6yrc:F, 6yrd:A, 6yrd:B, 6yrd:C, 6yrd:D, 6yrd:E, 6yrd:F, 6yrj:A, 6yrj:B, 6yrj:C, 6yrj:D, 6yrj:E, 6yrj:F, 7zmj:A, 7zmj:B, 7zmj:C, 7zmj:D, 7zmj:E, 7zmj:F
19 7qyq:B 284 200 0.1302 0.1761 0.2500 3.49e-04 7qyq:A, 7qyq:C, 7qyq:D, 7qyz:A, 7qza:A, 7qza:B, 7qza:C, 7qza:D, 7qza:E, 7qza:F, 7qza:G, 7qza:H
20 7bok:A 309 168 0.1016 0.1262 0.2321 5.83e-04 7bok:B, 7bok:C, 7bok:D, 7bok:E, 7bok:F
21 4au9:A 448 220 0.1328 0.1138 0.2318 0.001 5ag0:A, 5ag0:B, 5ag1:A, 5ag1:B, 4au9:B, 5ikd:A, 5ikg:A, 4uzi:A, 4uzi:B, 4w7j:A, 4w7j:B, 4w7j:C, 4w7j:D, 4w7k:A, 4w7k:B, 4w7l:A, 4w7l:B, 4w7m:A, 4w7m:B, 4w7n:A, 4w7n:B, 4w7o:A
22 5vj0:D 300 243 0.1484 0.1900 0.2346 0.002 5gt2:A, 5gt2:B, 5gt2:C, 5gt2:D, 5vj0:A, 5vj0:B, 5vj0:C
23 7d8m:A 451 227 0.1458 0.1242 0.2467 0.002
24 3qns:A 311 259 0.1510 0.1865 0.2239 0.004 4hov:A, 4hov:B, 4hov:C, 3qnr:A, 3qnr:B, 3qnr:C, 3vec:A, 3vec:B, 3vec:C, 3ved:A, 3ved:B, 3ved:C, 3vee:A, 3vee:B, 3vee:C, 3vef:A, 3vef:B, 3vef:C, 3veg:A, 3veg:B, 3veg:C
25 3afv:A 439 185 0.1302 0.1139 0.2703 0.007 2d3q:A, 2d3q:B, 3mm1:A, 3mm2:A, 3mm3:A, 3vxi:A, 3vxj:A
26 6fsk:A 484 168 0.1120 0.0888 0.2560 0.009 6fsk:B, 6fsl:A, 6fsl:B
27 8re3:A 445 155 0.1042 0.0899 0.2581 0.028 8re2:A, 8re3:B
28 6fiy:B 303 182 0.1094 0.1386 0.2308 0.074 6fiy:A, 6fks:A, 6fks:B, 6fkt:A, 6fkt:B, 6fl2:A, 6fl2:B, 6rpd:A, 6rpd:B, 6rpe:A, 6rpe:B, 6rqy:A, 6rqy:B, 6rr1:A, 6rr1:B, 6rr4:A, 6rr4:B, 6rr5:A, 6rr5:B, 6rr6:A, 6rr6:B, 6rr8:A, 6rr8:B
29 4g2c:B 463 120 0.0859 0.0713 0.2750 0.14 4g2c:A
30 5c2i:A 468 114 0.0885 0.0726 0.2982 0.22 5c2i:B, 5c2i:C, 5c2i:D
31 8wgh:K 83 49 0.0469 0.2169 0.3673 2.3
32 5ysz:A 327 92 0.0521 0.0612 0.2174 3.3
33 6sl5:K 84 49 0.0469 0.2143 0.3673 4.9
34 8j6z:K 84 46 0.0443 0.2024 0.3696 6.9 7dkz:K, 8j7b:K, 5l8r:K, 4rku:K, 6yac:K, 6yez:K, 6zoo:K, 6zxs:K
35 2zy2:A 521 56 0.0547 0.0403 0.3750 7.3
36 2x98:A 430 37 0.0417 0.0372 0.4324 8.0 2x98:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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