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TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
RRFGYAIVGLGKYALNQILPGFAGCQHSRIEALVDGNAEKAKIVAAEYGVDPRKIYDYSNFDKIAKDPKIDAVYIILPNS
LHAEFAIRAFKAGKHVMCEKPMATSVADCQRMIDAAKAANKKLMIGYRCHYDPMNRAAVKLIRENQLGKLGMVTTDNSDV
MDQNDPAQQWRLRRELAGGGSLMDIGIYGLNGTRYLLGEEPIEVRAYTYSDPNDERFVEVEDRIIWQMRFRSGALSHGAS
SYSTTTTSRFSVQGDKAVLLMDPATGYYQNLISVQTPANNQFSAQLDHLAEAVINNKPVRSPGEEGMQDVRLIQAIYEAA
RTGRPVNTDWGYVRQGGY

The query sequence (length=338) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 1h6d:A 383 352 0.9970 0.8799 0.9574 0.0 1evj:A, 1evj:B, 1evj:C, 1evj:D, 1h6a:A, 1h6a:B, 1h6b:A, 1h6b:B, 1h6c:A, 1h6c:B, 1h6d:C, 1h6d:B, 1h6d:D, 1h6d:E, 1h6d:G, 1h6d:F, 1h6d:H, 1h6d:I, 1h6d:K, 1h6d:J, 1h6d:L, 1ofg:A, 1ofg:D, 1ofg:B, 1ofg:C, 1ofg:E, 1ofg:F, 1ryd:A, 1ryd:B, 1rye:A, 1rye:D, 1rye:B, 1rye:C
2 5a03:C 336 338 0.4970 0.5000 0.4970 4.76e-107 5a02:A, 5a02:B, 5a02:C, 5a02:D, 5a02:E, 5a02:F, 5a03:A, 5a03:B, 5a03:D, 5a03:E, 5a03:F, 5a04:A, 5a04:B, 5a04:C, 5a04:D, 5a04:E, 5a04:F, 5a05:A, 5a05:C, 5a05:D, 5a05:E, 5a05:B, 5a05:F, 5a06:A, 5a06:B, 5a06:C, 5a06:D, 5a06:E, 5a06:F
3 2glx:A 332 317 0.2456 0.2500 0.2618 2.96e-27 2glx:B, 2glx:C, 2glx:D, 2glx:E, 2glx:F
4 4koa:A 333 316 0.2574 0.2613 0.2753 4.39e-25
5 3rc1:A 325 329 0.2308 0.2400 0.2371 9.72e-24 3rbv:A, 3rc2:A, 3rc7:A, 3rc9:A, 3rcb:A
6 3e18:A 348 365 0.2781 0.2701 0.2575 4.90e-22 3e18:B
7 3q2k:K 322 328 0.2515 0.2640 0.2591 1.07e-21 3q2k:E, 3q2k:L, 3q2k:P
8 7xre:C 363 305 0.2160 0.2011 0.2393 1.20e-20 7xr9:A, 7xr9:B, 7xr9:C, 7xr9:D, 7xr9:E, 7xr9:F, 7xre:A, 7xre:B, 7xre:D, 7xre:E, 7xre:F
9 6ktk:C 368 378 0.3225 0.2962 0.2884 1.24e-20 6ktk:A, 6ktk:B, 6ktk:D, 6ktl:A, 6ktl:B, 6ktl:C, 6ktl:D, 5ya8:A, 5ya8:B, 5ya8:C, 5ya8:D, 5yap:A, 5yap:B, 5yap:C, 5yap:D, 5yaq:A, 5yaq:B, 5yaq:C, 5yaq:D
10 6a3j:C 378 253 0.2249 0.2011 0.3004 2.48e-20 6a3g:A, 6a3g:B, 6a3g:C, 6a3g:D, 6a3i:A, 6a3i:B, 6a3i:C, 6a3i:D, 6a3j:A, 6a3j:B, 6a3j:D
11 3q2k:C 347 348 0.2574 0.2507 0.2500 7.59e-19 3q2k:A, 3q2k:B, 3q2k:D, 3q2k:F, 3q2k:G, 3q2k:H, 3q2k:I, 3q2k:J, 3q2k:M, 3q2k:N, 3q2k:O
12 7x2y:A 342 204 0.1864 0.1842 0.3088 1.53e-18 7x1x:A, 7x1x:B, 7x2y:B
13 6z3c:AAA 379 322 0.2426 0.2164 0.2547 1.39e-17 6z3b:A, 6z3b:B, 6z3c:BBB
14 6jw7:A 342 261 0.2012 0.1988 0.2605 2.12e-17 6jw6:A, 6jw6:B, 6jw7:B, 6jw8:A, 6jw8:B
15 6o15:A 355 239 0.1982 0.1887 0.2803 1.66e-16 6o15:B
16 3q2i:A 345 342 0.2633 0.2580 0.2602 5.97e-16
17 1zh8:A 325 325 0.2308 0.2400 0.2400 8.94e-16 1zh8:B
18 4n54:A 340 341 0.2367 0.2353 0.2346 6.58e-15 4n54:B, 4n54:C, 4n54:D
19 8tdi:G 386 363 0.2515 0.2202 0.2342 6.64e-14 8tdi:L, 8tdi:J, 8tdi:A, 8tdi:C, 8tdi:D, 8tdi:E, 8tdi:F, 8tdi:H, 8tdi:I, 8tdi:B, 8tdi:K
20 3ec7:A 336 148 0.1272 0.1280 0.2905 7.68e-14 3ec7:B, 3ec7:C, 3ec7:D, 3ec7:E, 3ec7:F, 3ec7:G, 3ec7:H
21 2o4u:X 331 197 0.1420 0.1450 0.2437 1.16e-13 2poq:X
22 3cea:A 342 346 0.2071 0.2047 0.2023 1.82e-13 3cea:B, 3cea:C, 3cea:D
23 6nor:A 349 293 0.2012 0.1948 0.2321 3.18e-13 6nor:B, 6nor:C, 6nor:D, 6nor:E, 6nor:F
24 7d5m:A 389 169 0.1391 0.1208 0.2781 2.38e-12 7d5n:A, 7d5n:B
25 5b3u:B 317 278 0.2189 0.2334 0.2662 2.54e-11 5b3v:B, 5b3v:A, 5b3v:C, 5b3v:D
26 4l8v:A 337 124 0.1124 0.1128 0.3065 8.92e-11 4l8v:B, 4l8v:C, 4l8v:D, 3nt2:A, 3nt2:B, 3nt4:A, 3nt4:B, 3nt5:A, 3nt5:B, 3ntq:A, 3ntq:B, 3ntr:A, 3ntr:B
27 9azo:A 315 142 0.1154 0.1238 0.2746 1.55e-10 9azo:B, 9azo:C, 9azo:D, 9azo:E, 9azo:F
28 8qc8:D 339 349 0.2249 0.2242 0.2178 3.78e-09
29 4nhe:B 326 130 0.1124 0.1166 0.2923 8.43e-08 4nhe:A, 4nhe:C
30 4min:A 339 130 0.0888 0.0885 0.2308 1.45e-07 4min:B, 4min:C, 4min:D, 4mio:A, 4mio:B, 4mio:C, 4mio:D, 4miy:A, 4miy:B, 4miy:C, 4miy:D, 4mjl:A, 4mjl:B, 4mjl:C, 4mjl:D
31 5uhw:A 342 354 0.2101 0.2076 0.2006 2.15e-07 5uhw:B, 5uhz:A, 5uhz:B, 5ui9:A, 5ui9:B, 5uia:A, 5uia:B, 5uib:A, 5uib:B
32 3m2t:A 342 117 0.1006 0.0994 0.2906 5.06e-07 3m2t:B
33 3dty:A 374 110 0.1006 0.0909 0.3091 6.75e-07 3dty:E
34 8qc8:B 367 235 0.1598 0.1471 0.2298 2.57e-06 8qc2:A, 8qc2:B, 8qc2:C, 8qc2:D, 8qc8:C, 8qc8:A
35 2ixa:A 426 113 0.0917 0.0728 0.2743 7.31e-06 2ixb:A
36 6t2b:B 439 87 0.0740 0.0569 0.2874 3.84e-05 6t2b:A, 6t2b:C, 6t2b:D
37 7cgq:A 306 213 0.1657 0.1830 0.2629 4.20e-05 7cgq:B, 7cgq:C, 7cgq:D, 7cgr:A, 7cgr:B, 7cgr:C, 7cgr:D, 6jnk:A, 6jnk:B, 6jnk:C, 6jnk:D
38 7bvj:A 313 147 0.1154 0.1246 0.2653 1.66e-04 7bvj:B, 7bvj:C, 7bvj:D, 7bvk:A, 7bvk:B
39 8qc6:A 366 376 0.2278 0.2104 0.2048 2.09e-04 8qc3:A, 8qc3:B, 8qc5:A, 8qc5:B, 8qc6:B
40 8tdf:A 452 133 0.1095 0.0819 0.2782 4.26e-04 8tdf:B, 8tdf:C, 8tdf:D, 8tdh:B, 8tdh:C, 8tdh:D, 8tdh:A
41 1lc3:A 292 58 0.0562 0.0651 0.3276 0.003 1lc0:A
42 2h63:D 285 55 0.0533 0.0632 0.3273 0.007 2h63:A, 2h63:B, 2h63:C
43 4itb:A 453 141 0.1124 0.0839 0.2695 0.038 4ita:A, 4ita:B, 4itb:B, 3vz3:A, 3vz3:B
44 6m5a:A 844 98 0.0888 0.0355 0.3061 0.12
45 5bsm:A 530 91 0.0740 0.0472 0.2747 0.95 5bsm:B, 5bsr:A, 5bst:A, 5bsu:A, 5bsv:A, 5bsw:A, 5bsw:B, 5u95:D, 5u95:B, 5u95:C
46 7qep:L5 283 45 0.0592 0.0707 0.4444 1.6
47 3oa2:B 311 54 0.0444 0.0482 0.2778 2.4 3oa2:A, 3oa2:C, 3oa2:D
48 4kir:A 460 71 0.0473 0.0348 0.2254 4.3 4kir:B, 4kqn:A, 4kqn:B, 1yny:A, 1yny:B
49 8eui:R 149 49 0.0473 0.1074 0.3265 5.7 8etg:R, 8etj:R, 8eug:R
50 1ycf:A 398 55 0.0562 0.0477 0.3455 5.9 1ycf:B, 1ycf:C, 1ycf:D, 1ycg:A, 1ycg:B, 1ycg:C, 1ycg:D, 1ych:A, 1ych:B, 1ych:C, 1ych:D
51 3o9z:A 310 269 0.1598 0.1742 0.2007 6.4 3o9z:B, 3o9z:C, 3o9z:D, 3oa0:A, 3oa0:B, 3oa0:C, 3oa0:D
52 6xyw:Aj 155 57 0.0562 0.1226 0.3333 8.2
53 2r7d:A 461 35 0.0385 0.0282 0.3714 8.2 2r7d:B, 2r7d:C

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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