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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
RQWQPDVEWAEQFGGAVMYPTKETAHWKPPPWNDVDPPKDTLVSNLTLNFRLVMELSGEMVRKCDPHIGLLHRGTEKLIE
YKTYLQALPYFDRLDYVSMMCNEQAYSLAVEKLLNIQPPPRAQWIRVLFGEITRLLNHIMAVTTHALDIGAMTPFFWMFE
EREKMFEFYERVSGARMHAAYIRPGGVHQDLPLGLLDDIYEFSKNFSFRIDELEEMLTNNRIWRNRTVDIGVVTAEDALN
YGFSGVMLRGSGIQWDLRKTQPYDVYDQVEFDVPIGSRGDCYDRYLCRVEEMRQSLRIISQCLNKMPPGEIKVDDAKVSP
PKRAEMKTSMESLIHHFKLYTEGYQVPPGATYTAIEAPKGEFGVYLVSDGSSRPYRCKIKAPGFAHLAGLDKMSKGHMLA
DVVAIIGTQDIVFGEVDR

The query sequence (length=418) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7b93:D 430 429 0.9593 0.9326 0.9347 0.0 7ak5:D, 8c2s:D, 8ca3:D, 8ca5:D, 6g2j:D, 6g72:D, 5gpn:Z, 5gup:C, 8iao:D, 8iap:D, 8ib4:D, 8ib5:D, 8ib9:D, 8iba:D, 8ic2:D, 8ic3:D, 5lc5:D, 5ldw:D, 5ldx:D, 5lnk:4, 8olt:D, 8om1:D, 7psa:D, 8pw5:D1, 8pw6:D1, 8pw7:D1, 8q0a:D, 8q0f:D, 8q0m:D, 8q0o:D, 8q0q:D, 8q1y:D, 8q25:D, 8q45:D, 8q46:D, 8q47:D, 8q48:D, 8q49:D, 8q4a:D, 6qa9:S2, 6qc4:S2, 6qc7:S2, 7qsd:D, 7qsk:D, 7qsl:D, 7qsm:D, 7qso:D, 7r41:D, 7r42:D, 7r43:D, 7r44:D, 7r45:D, 7r46:D, 7r47:D, 7r48:D, 7r4c:D, 7r4d:D, 7r4f:D, 7r4g:D, 8rgp:D, 8rgq:D, 8rgr:D, 8rgt:D, 8ud1:1D, 8uep:1D, 8ueq:1D, 8uer:1D, 8ues:1D, 8uet:1D, 8ueu:1D, 8uev:1D, 8uew:1D, 8uex:1D, 8uey:1D, 8uez:1D, 8ugh:1D, 8ugi:1D, 8ugj:1D, 8ugn:1D, 8ugn:5D, 8ugr:1D, 7v2c:Q, 7v2d:Q, 7v2e:Q, 7v2f:Q, 7v2h:Q, 7v2k:Q, 7v2r:Q, 7v30:Q, 7v31:Q, 7v32:Q, 7v33:Q, 7v3m:Q, 7vb7:Q, 7vbn:Q, 7vbz:Q, 7vwj:Q, 7vxp:Q, 7vxu:Q, 7vy8:Q, 7vya:Q, 7vyf:Q, 7vyh:Q, 7vyn:Q, 7vz1:Q, 7vzv:Q, 7vzw:Q, 7w00:Q, 7w0h:Q, 7w0r:Q, 7w0y:Q, 7w1o:Q, 7w1p:Q, 7w1t:Q, 7w1u:Q, 7w1v:Q, 7w1z:Q, 7w20:Q, 7w2k:Q, 7w2l:Q, 7w2r:Q, 7w2u:Q, 7w2y:Q, 7w31:Q, 7w32:Q, 7w35:Q, 7w4c:Q, 7w4d:Q, 7w4e:Q, 7w4f:Q, 7w4g:Q, 7w4j:Q, 7w4k:Q, 7w4l:Q, 7w4m:Q, 7w4n:Q, 7w4q:Q, 5xtb:Q, 7zd6:4, 7zdh:4, 7zdj:4, 7zdm:4, 7zdp:4, 7zeb:4, 6zkc:4, 6zkd:4, 6zke:4, 6zkf:4, 6zkg:4, 6zkh:4, 6zki:4, 6zkj:4, 6zkk:4, 6zkl:4, 6zkm:4, 6zkn:4, 6zko:4, 6zkp:4, 6zkq:4, 6zkr:4, 6zks:4, 6zkt:4, 6zku:4, 6zr2:D, 6ztq:D
2 7qsn:D 404 418 0.9474 0.9802 0.9474 0.0 6q9d:S2, 6zk9:4, 6zkv:4
3 8b9z:D 430 428 0.7799 0.7581 0.7617 0.0 8esz:S2
4 7aqr:D 385 385 0.6770 0.7351 0.7351 0.0 7a23:G, 7a24:G, 7ar7:D, 7ar8:D, 7arb:D, 8bee:D, 8bpx:D, 8bq5:D, 8bq6:D, 8e73:S2, 6x89:S2
5 7zmb:C 441 396 0.6483 0.6145 0.6843 0.0 7zm7:C, 7zmg:C
6 6rfr:C 438 399 0.6364 0.6073 0.6667 0.0 7o6y:C, 7o71:C, 6rfq:C, 6rfs:C, 6y79:C, 6yj4:D
7 7arc:D 395 395 0.6268 0.6633 0.6633 0.0 7ard:D
8 8qby:D 410 390 0.5526 0.5634 0.5923 3.72e-173
9 8iuf:S2 394 387 0.4928 0.5228 0.5323 6.92e-149 8j9h:S2, 8j9i:S2, 8j9j:S2
10 8b6f:AE 441 436 0.4569 0.4331 0.4381 5.74e-128 8bqs:AE
11 6i0d:4 384 369 0.3995 0.4349 0.4526 2.29e-118 6i0d:E, 6i1p:E, 3i9v:4, 3iam:4, 3ias:4, 3ias:D, 3ias:M, 3ias:V, 3m9s:4, 3m9s:D, 6q8o:4, 6q8o:E, 6q8w:4, 6q8w:E, 6q8x:4, 6q8x:E, 2ybb:4
12 8e9h:D 407 387 0.3780 0.3882 0.4083 1.82e-106 8e9g:D
13 7p63:C 589 370 0.3493 0.2479 0.3946 1.28e-94 7nyr:D, 7nyu:D, 7nz1:D, 7p64:C, 7p69:C, 7p7c:C, 7p7j:C, 7p7l:C, 7p7m:C, 7z7r:C, 7z7s:C, 7z7t:C, 7z7v:C, 7z80:C, 7z83:C, 7z84:C, 7zc5:C, 7zci:C
14 7p7k:C 568 370 0.3349 0.2465 0.3784 8.81e-87 7p7e:C
15 8ugp:1D 221 133 0.2751 0.5204 0.8647 6.77e-72
16 8ugp:1D 221 109 0.2105 0.3982 0.8073 9.55e-50
17 6cfw:L 374 377 0.2512 0.2807 0.2785 1.23e-37
18 7z0s:E 532 371 0.2321 0.1823 0.2615 7.12e-30 7z0t:E
19 3ayx:A 595 81 0.0574 0.0403 0.2963 0.033 3ayx:C, 3ayz:A, 3ayz:C, 5y34:A, 5y34:C
20 3myr:D 561 115 0.0718 0.0535 0.2609 0.10 3myr:B, 3myr:F, 3myr:H
21 5xf9:D 455 146 0.0861 0.0791 0.2466 0.11 5xf9:H, 5xfa:D, 5xfa:H
22 2whd:B 319 60 0.0478 0.0627 0.3333 0.13 2whd:A
23 2xto:A 224 85 0.0526 0.0982 0.2588 0.57 2xtm:A, 2xtm:B, 2xtn:A, 2xto:B
24 7ebx:A 256 43 0.0407 0.0664 0.3953 2.9 7ec0:A, 7ec0:D, 7ec0:G, 7ec0:J, 7ec0:M
25 6ehq:L 551 98 0.0574 0.0436 0.2449 2.9 6ehq:M, 6ehs:L, 6ehs:M, 6en9:L, 6en9:M, 6g7m:L, 6g7m:M, 6gam:L, 6gam:M, 6gan:L, 6gan:M, 7nem:L, 7nem:M, 6syo:LLL, 6syo:MMM, 6syx:LLL, 6syx:MMM, 6szd:LLL, 6szd:MMM, 6szk:LLL, 6szk:MMM, 7vxq:A, 7vxq:C, 5xvb:L, 5xvb:M, 5xvc:L, 5xvc:M, 5xvd:L, 5xvd:M
26 7b0n:G 694 37 0.0359 0.0216 0.4054 3.1 6gcs:A, 7o6y:A, 7o71:A, 6rfq:A, 6rfr:A, 6rfs:A, 6y79:A, 6yj4:G
27 7cyi:D 378 41 0.0335 0.0370 0.3415 3.3 7cyi:A, 7cyi:B, 7cyi:C, 6ljh:A
28 8w1o:K 1290 52 0.0359 0.0116 0.2885 4.0
29 5hq4:A 662 39 0.0359 0.0227 0.3846 5.7 5hqa:A, 5hqb:A, 5hqc:A
30 7pkt:w 120 50 0.0359 0.1250 0.3000 6.9
31 5ls9:F 165 58 0.0431 0.1091 0.3103 7.2 5ls9:I, 1s3q:A, 1s3q:B, 1s3q:C, 1s3q:D, 1s3q:E, 1s3q:F, 1s3q:G, 1s3q:H, 1s3q:I, 1s3q:J, 1s3q:K, 1s3q:L, 1sq3:A, 1sq3:B, 1sq3:C, 1sq3:D, 1sq3:E, 1sq3:F, 1sq3:G, 1sq3:H, 1sq3:I, 1sq3:J, 1sq3:K, 1sq3:L
32 1vdc:A 322 55 0.0455 0.0590 0.3455 7.5

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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