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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
RPYQEKSLSKMFGNGRARSGIIVLPCGAGKTLVGITAACTIKKSVIVLCTSSVSVMQWRQQFLAAAAAAAAAAAAAAAAA
AAAAAAAAALVVSTYSMVANAAAAAAAAAAAAAAAAAAAWGFIILDEVHVVPAAMFRRVVSTIAAHAKLGLTATLVREDD
KIGDLNFLIGPKLYEANWMELSQKGHIANVQCAEVWCPMTAEFYQEYLRETARKRMLLYIMNPTKFQACQFLIQYHERRG
DKIIVFSDNVYALQEYALKMGKPFIYGSTPQQERMNILQNFQYNDQINTIFLSKVGDTSIDLPEATCLIQISSHYGSRRQ
EAQRLGRILRAKRRNDEGFNAFFYSLVSKDTQEMYYSTKRQAFLVDQGYAFKVITHLHGMENIPNLAYASPRERRELLQE
VLLKNEEA

The query sequence (length=408) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6gym:7 408 408 1.0000 1.0000 1.0000 0.0 5oqj:7, 5oqm:7
2 7k04:7 638 408 0.8922 0.5705 0.8922 0.0 5fmf:1, 7m2u:7, 7ml0:7, 7ml1:7, 7ml2:7, 5sva:Z
3 7zsa:7 616 405 0.8848 0.5860 0.8914 0.0 8cen:7, 8ceo:7, 7o4i:7, 7o4j:7, 7o4k:7, 7o4l:7, 7o72:7, 7o73:7, 7o75:7, 7zs9:7, 7zsb:7
4 7ml3:7 548 404 0.8824 0.6569 0.8911 0.0
5 7lbm:W 574 403 0.6299 0.4477 0.6377 0.0
6 7ena:6 652 403 0.6299 0.3942 0.6377 0.0 7ad8:A, 8bvw:0, 8ebs:A, 8ebv:A, 8ebw:A, 7egb:6, 7egc:6, 7enc:6, 8gxq:HH, 8gxs:HH, 5ivw:V, 5iy6:V, 5iy7:V, 5iy8:V, 5iy9:V, 7nvr:7, 7nvv:7, 7nvw:7, 7nvx:7, 7nvy:7, 7nvz:7, 7nw0:7, 6o9l:7, 6ro4:A, 8wak:6, 8wal:6, 8wan:6, 8wao:6, 8wap:6, 8waq:6, 8war:6, 8was:6
7 8ebu:A 604 402 0.6225 0.4205 0.6318 0.0 8ebt:A, 8ebx:A, 8eby:A
8 6p4f:C 436 375 0.2353 0.2202 0.2560 2.01e-22 6p4f:A, 6p4w:A
9 1z63:A 468 139 0.0956 0.0833 0.2806 0.002 1z63:B
10 7r7j:B 574 166 0.0956 0.0679 0.2349 0.089 8h5y:B, 8h5y:A, 8h5z:B, 8h5z:A, 6jde:B, 6jde:A, 7r7j:A
11 6l5n:A 377 96 0.0662 0.0716 0.2812 0.39 6l5m:A, 6l5m:B, 6l5m:C, 6l5m:D, 6l5m:E, 6l5n:B, 6l5o:A
12 7vyx:A 1211 80 0.0539 0.0182 0.2750 1.3 7vyx:B
13 6m13:b 688 73 0.0515 0.0305 0.2877 1.5 7dsy:a, 7dsy:b, 7dts:a, 7dts:b, 7elw:a, 7elw:b, 6m11:a, 6m11:b, 6m12:a, 6m12:b, 6m13:a, 4o1o:A, 4o1o:B, 4o1o:C, 4o1o:D, 4o1p:A, 4o1p:B, 4o1p:C, 4o1p:D
14 1e3a:B 560 102 0.0686 0.0500 0.2745 2.6 1ai4:B, 1ai5:B, 1ai6:B, 1ai7:B, 1ajn:B, 1ajp:B, 1ajq:B, 1fxh:B, 1fxv:B, 1gk9:B, 1gkf:B, 1gm7:B, 1gm8:B, 1gm9:B, 1h2g:B, 1jx9:B, 1k5q:B, 1k5s:B, 1k7d:B, 1kec:B, 1pnk:B, 1pnl:B, 1pnm:B
15 7xyf:K 656 141 0.0882 0.0549 0.2553 2.9 7xyg:K
16 6xeo:A 1118 115 0.0711 0.0259 0.2522 3.2
17 5lst:A 617 168 0.0956 0.0632 0.2321 3.5
18 6x2f:A 1144 67 0.0441 0.0157 0.2687 3.6 7ssg:A, 6x26:A, 6x2n:A, 6x43:A, 6x4w:A, 6x4y:A, 6x50:A
19 6gmo:A 439 70 0.0441 0.0410 0.2571 7.7 6gmo:B, 2gwc:A, 2gwc:B, 2gwc:C, 2gwc:D, 2gwc:E, 2gwc:F, 2gwc:G, 2gwc:H, 2gwd:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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