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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
RPQEFAAVDLGSNSFHMVIARVVDGAMQIIGRLKQRVHLADGLDENSVLSEEAMTRGLNCLSLFAERLQGFSPSSVCIVG
THTLRQATNAAEFLKRAEKVIPYPIEIISGNEEARLIFMGVEHTQPERGRKLVIDIGGGSTELVIGEDFEPRLVESRRMG
CVSFSQAYFPGGVINKENFQRARLAAVQKLETLAWQFRIQGWTVALGASGTIKAAQEVLVAMGEKDGFITPERLEMLVSE
LLKHKNFDALSLPGLSEDRKAVFAPGLAILCGVFDALAIKELRLSDGALREGVLYEMEGRFRHQDIRSRTAQSLANQYNI
DREQARRVLETTTQMLEQWQEQNPKLANPHLAALLKWAVMLHEVGLNINHSGMHRHSAYILQNSDLPGFNQEQQMLMATL
VRYHRKAIKLDDLPRFTLFRKKQFLPLIQLLRLGVLLNNQRQATTTPPTLRLQTEAHHWTLTFPHNWFSQNALVLLDLEK
EQQYWEGVPEWMLKIAEEEP

The query sequence (length=500) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8jgw:A 500 500 1.0000 1.0000 1.0000 0.0
2 8jgp:A 492 432 0.2380 0.2419 0.2755 4.34e-27 8jgo:A, 8jgq:A, 8jgr:A, 8jgt:A
3 1t6c:A 306 308 0.1740 0.2843 0.2825 3.32e-22 2j4r:A
4 6pc1:B 483 428 0.2080 0.2153 0.2430 9.43e-19 6pc1:A, 6pc1:C, 6pc1:D, 6pc2:A, 6pc2:B, 6pc3:A, 6pc3:B
5 7epq:A 296 315 0.1640 0.2770 0.2603 1.69e-10 7epq:B
6 3a25:A 264 30 0.0280 0.0530 0.4667 0.60 3a26:A
7 8a7l:A 346 79 0.0560 0.0809 0.3544 2.4 8a6v:A, 8a6v:B, 8a6z:A, 8a6z:B, 8a6z:C, 8a6z:D, 8a6z:E, 8a6z:F, 8a70:A, 8a73:A, 8a73:B, 8a74:A, 8a74:B, 8a78:A, 8a7a:A, 8a7b:A, 8a7c:A, 8a7c:B, 8a7j:A, 8a7j:B, 8a7k:A, 8a7k:B, 8a7r:A, 8a7u:A
8 5u7w:A 404 54 0.0300 0.0371 0.2778 4.0 5u7v:A
9 8a0x:A 103 44 0.0320 0.1553 0.3636 4.3 8a0w:A, 8a0w:B, 8a0x:B
10 7ml7:A 1216 80 0.0440 0.0181 0.2750 6.9
11 1bhg:A 611 51 0.0360 0.0295 0.3529 7.2 1bhg:B, 3hn3:A, 3hn3:B, 3hn3:D, 3hn3:E
12 6p4q:B 115 41 0.0300 0.1304 0.3659 7.3 7k7h:E, 6p4m:A, 6p4m:B, 6p4m:C, 6p4m:D, 6p4m:E, 6p4n:C, 6p4n:D, 6p4n:E, 6p4q:A, 6p4q:C, 6p4q:D, 6p4q:E, 6p4r:A, 6p4r:B, 6p4r:C, 6p4r:D, 6p4r:E, 6p4t:A, 6p4t:C, 6p4t:D, 4rhs:C, 4rhs:E, 6tyn:A, 6tyn:C, 6tyn:D, 6tyn:E, 6tyo:A, 6tyo:C, 6tyo:D, 6tyo:E, 6tyq:C, 6tyq:D, 6tyq:E, 5wht:A, 5wht:C, 5wht:B, 5wht:D
13 6lrt:A 423 125 0.0640 0.0757 0.2560 7.4 6lrt:D, 6lrt:G, 6lrt:J, 6lrt:M, 6lrt:P, 6lrt:S, 6lrt:V

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218