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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
RLGDIDFTGVSRTRGKFVRVTSSTDPAEIYQILTKQWGLAPPHLVVALMGGDEVAQLKPWLRDTLRKGLVKAAQSTGAWI
LTSGLRFGITKNLGQAVRDHSLASTSPKVRVVAIGIAPWNMIQNRDLLLSAKPDHPATYPTEDLPYGAVYSLDCNHSHFI
LVDEDPKRPGATGEMRVKMLKHISLQRTGYGGTGSIEIPVLCLLVHGEPRILQKMYKNIQNSIPWLILAGSGGVADILVT
LMDRGCWDADIVQELLINTFPDGLHSTEITSWTKLIQRILDHGHLLTVHDPEQDSELDTVILKALVKACKSQSQEAQDFL
DALKLAVAWNRVDIAKSEIFSGDVQWSAQDLEEVMMEALVNDKPDFVRLFVDNGVNIKQFLTYGRLQELYCSVSEKNLLH
TLLLKKNQERQAQLKFRFTFHEVSKVLKDFLDDTCKGFYQKLNLPDMDRRCEHPWRDLFLWAILQNRQEMANYFWAMGPE
AVAAALVGCKIMKEMAHLATEAESARSMKNAKYEQFAMDLFSECYSNSEDRAYSLLVRKTCCWSKATVLNIATLAEAKCF
FAHDGVQALLTKVWWGAMRTDTSISRLVLTFFIPPLVWTSLIKFNPESATFIRVVLRRWNRFWSAPVTVFMGNVIMYFAF
LILFSYVLLLDFRPPPPYGPSAAEIILYFWVFTLVLEEIRQSFFTDEDMSILKKMKLYVEDNWNKCDMVAISLFVVGLSC
RMAMSTYEAGRTVLALDFMVFTLRLIHIFAIHKQLGPKIIIVERMIKDVFFFLFFLSVWLIAYGVTTQALLHPNDPRIDW
VFRRALYRPYLHIFGQIPLEEIDAAKMPDDNCTTDVQEIILGTLPPCPNIYANWLVILLLVIYLLVTNVLLLNLLIAMFS
YTFQVVQENADIFWKFQRYNLIVEYHSRPALAPPFIIISHITQALLSFIKDLLERELPSGLDQKLMTWETVQKENYLAKL
EHEHRESSGERLRYTSSKVQTLLRMVGGFKDQEKRM

The query sequence (length=996) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7mbp:A 996 996 0.9990 0.9990 0.9990 0.0 7mbp:B, 7mbp:C, 7mbp:D, 7mbq:A, 7mbq:B, 7mbq:C, 7mbq:D, 7mbr:A, 7mbr:B, 7mbr:C, 7mbr:D, 7mbs:A, 7mbs:B, 7mbs:C, 7mbs:D, 7mbt:A, 7mbt:D, 7mbt:B, 7mbt:C, 7mbu:A, 7mbu:D, 7mbu:B, 7mbu:C, 7mbv:A, 7mbv:B, 7mbv:C, 7mbv:D
2 8slw:A 921 988 0.6024 0.6515 0.6073 0.0 8slp:D, 8slp:A, 8slp:B, 8slp:C, 8slw:B, 8slw:C, 8slw:D
3 8sli:A 894 987 0.5904 0.6577 0.5957 0.0 8sli:D, 8sli:C, 8sli:B
4 6bcq:B 983 1002 0.4649 0.4710 0.4621 0.0 6bco:B, 6bco:D, 6bco:A, 6bco:C, 6bcq:D, 6bcq:A, 6bcq:C
5 9b8w:A 993 1011 0.4739 0.4753 0.4669 0.0 9b8w:B, 9b8w:C, 9b8w:D, 9b8x:A, 9b8y:A, 9b8y:B, 9b8y:C, 9b8y:D, 9b8z:A, 9b90:A, 9b90:B, 9b90:C, 9b90:D, 9b91:A, 9b92:A, 9b92:B, 9b92:C, 9b92:D, 9b94:A, 9b94:B, 9b94:C, 9b94:D, 6bqr:A, 6bqr:C, 6bqr:B, 6bqr:D
6 5wp6:A 977 1018 0.4719 0.4811 0.4617 0.0 6bqv:A, 6bqv:C, 6bqv:B, 6bqv:D, 5wp6:B, 5wp6:C, 5wp6:D
7 8e6q:A 1348 1041 0.4197 0.3101 0.4015 0.0 8e6q:B, 8e6q:C, 8e6q:D, 8e6r:A, 8e6r:B, 8e6r:C, 8e6r:D, 8e6s:A, 8e6s:B, 8e6s:C, 8e6s:D, 8e6u:A, 8e6u:B, 8e6u:C, 8e6u:D, 6mj2:A, 6mj2:B, 6mj2:C, 6mj2:D
8 6puu:A 1309 1015 0.4127 0.3140 0.4049 0.0 8e6t:A, 8e6t:B, 8e6t:C, 8e6t:D, 6pur:A, 6pur:B, 6pur:C, 6pur:D, 6pus:A, 6pus:C, 6pus:D, 6pus:B, 6puu:B, 6puu:C, 6puu:D
9 6drj:A 1266 1033 0.3966 0.3120 0.3824 0.0 6d73:B, 6d73:D, 6drj:B, 6drj:C, 6drj:D
10 6d73:A 1227 1015 0.3956 0.3211 0.3882 0.0 6d73:C, 6pkx:B, 6pkx:D
11 9b6h:B 934 1005 0.3604 0.3844 0.3572 0.0 9b6d:A, 9b6d:B, 9b6d:C, 9b6d:D, 9b6e:B, 9b6e:A, 9b6e:C, 9b6e:D, 9b6f:A, 9b6f:B, 9b6f:C, 9b6f:D, 9b6g:A, 9b6g:B, 9b6g:C, 9b6g:D, 9b6h:A, 9b6h:C, 9b6h:D, 9b6k:A, 9b6k:B, 9b6k:C, 9b6k:D, 7wrb:A, 7wrb:B, 7wrb:C, 7wrb:D, 7wrc:A, 7wrc:B, 7wrc:C, 7wrc:D, 7wrd:A, 7wrd:B, 7wrd:C, 7wrd:D, 7wre:A, 7wre:B, 7wre:C, 7wre:D, 7wrf:A, 7wrf:B, 7wrf:C, 7wrf:D
12 8e4n:A 901 998 0.3554 0.3929 0.3547 0.0 9b6j:A, 9b6j:B, 9b6j:C, 9b6j:D, 8e4l:A, 8e4l:B, 8e4l:C, 8e4l:D, 8e4m:A, 8e4m:B, 8e4m:C, 8e4m:D, 8e4n:B, 8e4n:C, 8e4n:D, 8e4o:A, 8e4o:D, 8e4o:B, 8e4o:C, 8e4p:A, 8e4p:B, 8e4p:C, 8e4p:D
13 8bdc:A 963 998 0.3514 0.3634 0.3507 0.0 8bdc:B, 8bdc:C, 8bdc:D
14 6bwi:A 816 684 0.3353 0.4093 0.4883 0.0 6bwi:D, 6bwi:B, 6bwi:C
15 6o77:A 872 1006 0.3584 0.4094 0.3549 0.0 9b6i:A, 9b6i:B, 9b6i:C, 9b6i:D, 6o77:D, 6o77:B, 6o77:C
16 6o72:A 858 983 0.3454 0.4009 0.3499 0.0 6o72:B, 6o72:C, 6o72:D
17 6co7:A 1061 1052 0.3464 0.3252 0.3279 2.62e-170 6co7:B, 6co7:C, 6co7:D
18 6nr2:A 859 962 0.3293 0.3818 0.3410 2.39e-164 6nr2:B, 6nr2:C, 6nr2:D, 6nr3:A, 6nr3:B, 6nr3:C, 6nr3:D, 6o6a:A, 6o6a:B, 6o6a:C, 6o6a:D, 6o6r:A, 6o6r:B, 6o6r:C, 6o6r:D
19 8ddr:A 968 1009 0.3203 0.3295 0.3162 2.68e-161 8ddq:A, 8ddq:B, 8ddq:C, 8ddq:D, 8ddr:B, 8ddr:C, 8ddr:D, 8dds:A, 8dds:B, 8dds:C, 8dds:D, 8ddt:A, 8ddt:B, 8ddt:C, 8ddt:D, 8ddu:A, 8ddu:B, 8ddu:C, 8ddu:D, 8ddv:A, 8ddv:B, 8ddv:C, 8ddv:D, 8ddx:A, 8ddx:B, 8ddx:C, 8ed7:A, 8ed7:B, 8ed7:C, 8ed7:D, 8ed8:A, 8ed8:B, 8ed8:C, 8ed8:D, 8ed9:A, 8ed9:B, 8ed9:C, 8ed9:D
20 8ddx:D 992 1033 0.3223 0.3236 0.3107 1.15e-157
21 8si6:A 1107 1034 0.3092 0.2782 0.2979 8.97e-144 8si2:A, 8si2:B, 8si2:D, 8si2:C, 8si3:A, 8si3:B, 8si3:C, 8si3:D, 8si4:A, 8si4:B, 8si4:C, 8si4:D, 8si5:A, 8si5:B, 8si5:D, 8si5:C, 8si6:B, 8si6:C, 8si6:D, 8si7:A, 8si7:B, 8si7:D, 8si7:C, 8si8:A, 8si8:B, 8si8:D, 8si8:C, 8sia:A, 8sia:D, 8sia:B, 8sia:C, 8w2l:A, 8w2l:B, 8w2l:C, 8w2l:D
22 8sr8:A 1353 1063 0.2912 0.2143 0.2728 2.35e-94 8sr8:B, 8sr8:C, 8sr8:D, 8sr9:A, 8sr9:B, 8sr9:C, 8sr9:D, 8sra:A, 8sra:B, 8sra:C, 8sra:D, 8srb:A, 8srb:B, 8srb:C, 8srb:D
23 8sre:A 1377 1063 0.2912 0.2106 0.2728 5.12e-94 8sr7:A, 8sr7:B, 8sr7:C, 8sr7:D, 8src:A, 8src:B, 8src:C, 8src:D, 8srd:A, 8srd:B, 8srd:C, 8srd:D, 8sre:B, 8sre:D, 8sre:C, 8srf:A, 8srf:B, 8srf:C, 8srf:D, 8srg:A, 8srg:B, 8srg:C, 8srg:D, 8srh:A, 8srh:B, 8srh:C, 8srh:D, 8sri:A, 8sri:B, 8sri:C, 8sri:D, 8srj:A, 8srj:B, 8srj:D, 8srj:C, 8srk:A, 8srk:B, 8srk:C, 8srk:D
24 5zx5:B 814 715 0.2048 0.2506 0.2853 6.23e-93 5zx5:D, 5zx5:A, 5zx5:C
25 5zx5:B 814 55 0.0211 0.0258 0.3818 0.15 5zx5:D, 5zx5:A, 5zx5:C
26 8ddw:A 695 637 0.2028 0.2906 0.3171 4.54e-88 8ddw:B, 8ddw:C
27 8ddw:A 695 120 0.0361 0.0518 0.3000 4.18e-06 8ddw:B, 8ddw:C
28 8ddw:D 719 618 0.1978 0.2740 0.3188 5.74e-84
29 8ddw:D 719 119 0.0361 0.0501 0.3025 6.38e-06
30 8e6v:A 707 386 0.1546 0.2178 0.3990 4.69e-79
31 6bwd:A 771 550 0.1586 0.2049 0.2873 6.44e-72 6bwd:B, 6bwd:D, 6bwd:C
32 7aov:A 377 324 0.1165 0.3077 0.3580 9.25e-57 7aov:B
33 8gvw:A 671 516 0.1235 0.1833 0.2384 2.23e-17 6aei:A, 6aei:D, 6aei:B, 6aei:C, 7d4p:A, 7d4p:D, 7d4p:B, 7d4p:C, 7d4q:A, 7d4q:D, 7d4q:B, 7d4q:C, 7e4t:A, 7e4t:D, 7e4t:B, 7e4t:C, 8gvw:D, 8gvw:B, 8gvw:C, 7wdb:A, 7wdb:D, 7wdb:B, 7wdb:C
34 7x6i:A 687 517 0.1185 0.1718 0.2282 5.74e-16 8gvx:B, 8gvx:A, 8gvx:D, 8gvx:C, 7x6c:C, 7x6c:B, 7x6c:A, 7x6c:D, 7x6i:D, 7x6i:B, 7x6i:C, 6ysn:A, 6ysn:B, 6ysn:C, 6ysn:D
35 7b1g:A 691 294 0.0763 0.1100 0.2585 1.25e-13 7b05:A, 7b05:D, 7b05:B, 7b05:C, 7b0s:A, 7b0s:D, 7b0s:B, 7b0s:C, 7b16:A, 7b16:B, 7b16:C, 7b16:D, 7b1g:C, 7b1g:B, 7b1g:D, 6g1k:A, 6g1k:B, 6g1k:D, 6g1k:C
36 7b0j:A 682 342 0.0843 0.1232 0.2456 1.33e-13 7b0j:B, 7b0j:C, 7b0j:D
37 5z96:A 670 466 0.1124 0.1672 0.2403 8.77e-13 6jzo:A, 6jzo:D, 6jzo:B, 6jzo:C, 5z96:D, 5z96:B, 5z96:C
38 6pw5:B 782 407 0.0894 0.1138 0.2187 2.10e-11 6pw5:D
39 6pw5:A 734 407 0.0894 0.1213 0.2187 4.60e-11 6pw5:C
40 8t1b:A 644 306 0.0813 0.1258 0.2647 1.88e-07 4dx2:A, 8fc7:A, 8fc7:B, 8fc7:C, 8fc7:D, 8fc8:A, 8fc8:B, 8fc8:D, 8fc8:C, 8fcb:A, 8fcb:B, 8fcb:D, 8fcb:C, 8ju5:D, 8ju5:B, 8ju6:A, 8ju6:B, 8ju6:D, 8ju6:C, 8jvj:A, 8jvj:B, 8jvj:C, 8jvj:D, 8t1b:B, 8t1b:D, 8t1b:C, 8t1d:A, 8t1d:B, 8t1d:C, 8t1d:D, 8t1e:A, 8t1e:B, 8t1e:C, 8t1e:D, 8t1f:A, 8t1f:B, 8t1f:C, 8t1f:D
41 7dxb:A 738 191 0.0452 0.0610 0.2356 7.01e-06 6cud:A, 6cud:D, 6cud:B, 6cud:C, 7dxb:D, 7dxb:B, 7dxb:C, 7dxc:A, 7dxc:B, 7dxc:D, 7dxc:C, 7dxd:A, 7dxd:B, 7dxd:C, 7dxd:D, 7dxe:D, 7dxe:A, 7dxe:B, 7dxe:C
42 7lqy:A 659 300 0.0723 0.1093 0.2400 1.08e-05 8gf8:A, 8gf8:B, 8gf8:C, 8gf8:D, 8gf9:A, 8gf9:B, 8gf9:C, 8gf9:D, 8gfa:A, 8gfa:B, 8gfa:C, 8gfa:D, 8jqr:A, 8jqr:B, 8jqr:C, 8jqr:D, 7l2h:A, 7l2h:D, 7l2h:B, 7l2h:C, 7l2i:A, 7l2i:C, 7l2i:D, 7l2i:B, 7l2j:A, 7l2j:B, 7l2j:C, 7l2j:D, 7l2p:A, 7l2p:B, 7l2p:D, 7l2p:C, 7l2r:A, 7l2r:B, 7l2r:C, 7l2r:D, 7l2s:D, 7l2s:A, 7l2s:B, 7l2s:C, 7l2t:A, 7l2t:D, 7l2t:B, 7l2t:C, 7l2u:A, 7l2u:B, 7l2u:D, 7l2u:C, 7l2v:A, 7l2v:D, 7l2v:B, 7l2v:C, 7l2w:A, 7l2w:D, 7l2w:B, 7l2w:C, 7l2x:A, 7l2x:D, 7l2x:B, 7l2x:C, 7lp9:A, 7lp9:B, 7lp9:C, 7lp9:D, 7lqy:B, 7lqy:C, 7lqy:D, 7lqz:A, 7lqz:B, 7lqz:C, 7lqz:D, 7lr0:A, 7lr0:B, 7lr0:C, 7lr0:D, 7mz6:A, 7mz6:B, 7mz6:D, 7mz6:C, 7mz7:A, 7mz7:D, 7mz7:B, 7mz7:C, 7mz9:A, 7mz9:D, 7mz9:C, 7mz9:B, 7mza:A, 7mza:D, 7mza:B, 7mza:C, 7mzb:A, 7mzb:D, 7mzb:B, 7mzb:C, 7mzc:A, 7mzc:D, 7mzc:C, 7mzc:B, 7mzd:A, 7mzd:D, 7mzd:B, 7mzd:C, 7mze:A, 7mze:D, 7mze:B, 7mze:C, 2nyj:A, 2pnn:A, 7rqw:A, 7rqw:C, 7rqw:D, 7rqw:B, 7rqy:A, 7rqy:C, 7rqy:B, 7rqy:D, 7rqz:A, 7rqz:C, 7rqz:B, 7rqz:D, 8t0c:A, 8t0c:D, 8t0c:B, 8t0c:C, 8t0e:A, 8t0e:D, 8t0e:B, 8t0e:C, 8u30:A, 8u30:D, 8u30:B, 8u30:C, 8u3a:D, 8u3c:D, 8u43:A, 8u43:B, 8u43:C, 8u43:D, 8u4d:A, 8u4d:D, 8u4d:C, 8u4d:B, 8x94:A, 8x94:B, 8x94:C, 8x94:D
43 8jvi:B 604 290 0.0743 0.1225 0.2552 1.59e-05 8fca:A, 8fca:B, 8fca:C, 8fca:D, 8j1b:A, 8j1b:B, 8j1b:C, 8j1b:D, 8j1f:A, 8j1f:B, 8j1f:C, 8j1f:D, 8j1h:C, 8j1h:D, 8j1h:B, 8j1h:A, 8jvi:C, 8jvi:D, 8jvi:A
44 8v6l:A 653 156 0.0422 0.0643 0.2692 4.57e-05 6dvy:A, 6dvy:B, 6dvy:C, 6dvy:D, 6dvz:A, 6dvz:B, 6dvz:C, 6dvz:D, 7ugg:A, 7ugg:D, 7ugg:B, 7ugg:C, 8v6l:B, 8v6l:C, 8v6l:D, 8v6m:A, 8v6m:B, 8v6m:C, 8v6m:D, 8v6n:A, 8v6n:B, 8v6n:C, 8v6n:D, 8v6o:A, 8v6o:B, 8v6o:C, 8v6o:D, 7xj1:C, 7xj1:A
45 6ot5:A 623 157 0.0412 0.0658 0.2611 5.56e-05 6ot5:B, 6ot5:C, 6ot5:D, 7ras:A, 7ras:B, 7ras:C, 7ras:D, 7rau:A, 7rau:B, 7rau:C, 7rau:D, 6uw4:A, 6uw4:D, 6uw4:B, 6uw4:C, 6uw6:A, 6uw6:D, 6uw6:B, 6uw6:C, 7xj0:B, 7xj0:A, 7xj0:C, 7xj0:D, 7xj1:B, 7xj1:D, 7xj2:B, 7xj2:C, 7xj2:D, 7xj2:A
46 6uz8:A 734 195 0.0422 0.0572 0.2154 7.80e-05 6uz8:D, 6uz8:C, 6uz8:B, 6uza:A, 6uza:B, 6uza:C, 6uza:D
47 6pw4:A 696 69 0.0211 0.0302 0.3043 1.68e-04 6pw4:C
48 6pw4:B 675 65 0.0201 0.0296 0.3077 2.97e-04 6pw4:D
49 7rqu:A 604 299 0.0673 0.1109 0.2241 4.53e-04 5irx:A, 5irx:B, 5irx:D, 5irx:C, 5irz:D, 5irz:E, 5irz:B, 5irz:C, 5is0:C, 5is0:B, 5is0:D, 5is0:E, 7l2l:A, 7l2l:D, 7l2l:C, 7l2l:B, 7l2m:A, 7l2m:C, 7l2m:D, 7l2m:B, 7l2n:A, 7l2n:D, 7l2n:C, 7l2n:B, 7l2o:A, 7l2o:C, 7l2o:D, 7l2o:B, 7lpa:A, 7lpa:B, 7lpa:D, 7lpa:C, 7lpb:A, 7lpb:B, 7lpb:C, 7lpb:D, 7lpc:C, 7lpc:A, 7lpc:B, 7lpc:D, 7lpd:A, 7lpd:B, 7lpd:C, 7lpd:D, 7lpe:C, 7lpe:B, 7lpe:A, 7lpe:D, 7mz5:A, 7mz5:D, 7mz5:C, 7mz5:B, 7rqu:C, 7rqu:B, 7rqu:D, 7rqv:A, 7rqv:D, 7rqv:C, 7rqv:B, 7rqx:A, 7rqx:C, 7rqx:D, 7rqx:B, 8t0y:B, 8t0y:A, 8t0y:D, 8t0y:C, 8t10:B, 8t10:A, 8t10:D, 8t10:C, 8t3l:A, 8t3l:D, 8t3l:B, 8t3l:C, 8t3m:A, 8t3m:D, 8t3m:C, 8t3m:B, 8u2z:A, 8u2z:D, 8u2z:B, 8u2z:C
50 7dxg:A 698 429 0.0863 0.1232 0.2005 0.003 7dxf:A, 7dxf:D, 7dxf:B, 7dxf:C, 7dxg:D, 7dxg:C, 7dxg:B
51 8r6s:E 1091 123 0.0351 0.0321 0.2846 0.10 8rdj:E
52 8u3a:A 284 43 0.0201 0.0704 0.4651 0.15 8u3c:A
53 4py5:A 267 143 0.0341 0.1273 0.2378 0.24
54 6whg:A 523 151 0.0442 0.0841 0.2914 0.44 6whg:B, 6whg:C, 6whg:D
55 8ssn:B 386 63 0.0231 0.0596 0.3651 3.8
56 6ray:3 600 72 0.0221 0.0367 0.3056 3.9 6raw:3, 6raz:3
57 4jic:A 370 151 0.0442 0.1189 0.2914 4.3 4jic:B, 4jic:C, 4jip:A, 4jiq:A, 5n6g:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218