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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
QVIARAASIMRALGSHPHGLSLAAIAQLVGLPRSTVQRIINALEEEFLVEALGPAGGFRLGPALGQLINQAQTDILSLVK
PYLRSLAEELDESVSLASLAGDKIYVLDRIVSERELRVVFPIGINVPAAATAAGKVLLAALPDETLQAALGEQLPVLTSN
TLGRKALVKQLSEVRQSGVASDLDEHIDGVSSFATLLDTYLGYYSLAIVMPSSRASKQSDLIKKALLQSKLNIERAIGR

The query sequence (length=239) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 2xro:B 240 239 1.0000 0.9958 1.0000 8.82e-170 2xro:A, 2xro:E, 2xro:F
2 8eju:B 257 197 0.2343 0.2179 0.2843 1.30e-11 8eju:A
3 2o99:C 182 147 0.1883 0.2473 0.3061 9.52e-11 2o99:A, 2o99:B, 2o99:D, 2o9a:A, 2o9a:B, 2o9a:C, 2o9a:D
4 1mkm:A 246 208 0.2008 0.1951 0.2308 3.38e-07
5 4s13:A 472 180 0.1883 0.0953 0.2500 0.002 4s13:G
6 1hw5:A 208 43 0.0711 0.0817 0.3953 0.031 6b6h:G, 6b6h:H, 1cgp:A, 1cgp:B, 2cgp:A, 5ciz:A, 6dt4:A, 6dt4:B, 4ft8:A, 4ft8:B, 3fwe:A, 1g6n:A, 1g6n:B, 2gzw:A, 2gzw:B, 2gzw:C, 2gzw:D, 1hw5:B, 4hzf:A, 4hzf:B, 4i01:A, 4i01:B, 4i02:A, 4i02:B, 4i02:C, 4i02:D, 4i02:E, 4i02:F, 4i09:A, 4i09:B, 4i0a:A, 4i0a:B, 4i0b:A, 4i0b:B, 1i5z:A, 1i5z:B, 1i6x:A, 1i6x:B, 3iyd:G, 3iyd:H, 1j59:A, 1j59:B, 3kcc:A, 3kcc:B, 1lb2:A, 3n4m:A, 4n9i:A, 4n9i:B, 4n9i:C, 4n9i:D, 1o3q:A, 1o3r:A, 1o3s:A, 1o3t:A, 1o3t:B, 6pb4:G, 6pb4:H, 6pb5:G, 6pb5:H, 6pb6:H, 6pb6:G, 3qop:A, 3qop:B, 4r8h:A, 4r8h:B, 3rdi:A, 3rdi:B, 3rou:A, 3rou:B, 3rpq:A, 3rpq:B, 1run:A, 1run:B, 1ruo:A, 1ruo:B, 3ryp:A, 3ryp:B, 3ryr:A, 3ryr:B, 1zrc:A, 1zrc:B, 1zrd:A, 1zrd:B, 1zre:A, 1zre:B, 1zrf:A, 1zrf:B
7 5hpf:A 175 76 0.1172 0.1600 0.3684 0.040 5hpf:C, 5hpi:A, 5hpi:B, 5hpi:C, 5hpi:D
8 7ff0:A 206 45 0.0628 0.0728 0.3333 0.18 7few:A, 7few:B, 7ff0:B, 7ff8:A, 7ff8:B, 7ff9:A, 7ff9:B, 7ff9:C, 7ff9:D, 7ff9:E, 7ff9:F, 7ff9:G, 7ff9:H, 2oz6:A
9 5whm:A 263 247 0.2301 0.2091 0.2227 0.24
10 7bkd:A 664 57 0.0753 0.0271 0.3158 1.5 7bkb:A, 7bkb:a, 7bkc:A, 7bkc:a, 7bkd:a, 7bke:A, 7bke:a
11 2exu:A 192 27 0.0502 0.0625 0.4444 3.0
12 7yhq:A 393 40 0.0753 0.0458 0.4500 4.3
13 7nkx:Z 156 27 0.0502 0.0769 0.4444 5.3
14 3av8:A 97 67 0.0795 0.1959 0.2836 7.6 3av8:B, 3av8:C, 3av8:D, 1fxi:A, 1fxi:B, 1fxi:C, 1fxi:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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