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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
QVAPKWYQSEDVPAPKQTRKTARPQKLRASLVPGTVLILLAGRFRGKRVVYLKNLEDNTLLVSGPFKVNGVPLRRVNARY
VIATSTKVNVSGVDVSKFNVEYFAREKEIKAERVADQKSVDAALLSEIKKTPLLKQYLAASFSLKNGDRPHLLKF

The query sequence (length=155) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8c3a:n 157 155 1.0000 0.9873 1.0000 3.27e-111 8c3a:BA, 8cq7:n, 8cq7:BA, 8cqw:n, 8cqw:BA, 8cre:n, 8cre:BA, 8oeq:n, 8oeq:BA, 7pzy:n, 7q08:n, 7q0f:n, 7q0p:n, 7q0r:n, 8q5i:n
2 5dat:l6 157 155 0.8645 0.8535 0.8645 5.93e-96 7azy:A, 8bn3:L6, 7bt6:E, 7btb:E, 8ccs:II, 8cdl:II, 8cdr:II, 8ceh:II, 8cf5:II, 8cg8:II, 8cgn:II, 8civ:II, 8cku:II, 8cmj:II, 5dat:L6, 5dc3:L6, 5dc3:l6, 5dge:L6, 5dge:l6, 5dgf:L6, 5dgf:l6, 5dgv:L6, 5dgv:l6, 8e5t:E, 6elz:E, 6em1:E, 6em3:E, 6em4:E, 6em5:E, 8eub:AE, 8evp:AE, 8evq:AE, 8evr:AE, 8evs:AE, 8evt:AE, 8ewb:AE, 8ewc:AE, 5fci:L6, 5fci:l6, 5fcj:L6, 5fcj:l6, 6ft6:E, 5gak:I, 6gq1:E, 6gqb:E, 6gqv:E, 5h4p:E, 6hd7:I, 6hhq:n, 6hhq:CH, 5i4l:L6, 5i4l:l6, 6i7o:BM, 6i7o:YM, 3j6x:L6, 3j6y:L6, 3j77:L6, 3j78:L6, 3jct:E, 5jcs:E, 8k2d:LE, 8k82:LE, 5lyb:L6, 5lyb:l6, 5m1j:E5, 6m62:E, 5mc6:BM, 5mei:n, 5mei:CH, 7mpi:AE, 7mpj:AE, 6n8m:H, 6n8n:H, 6n8o:H, 7n8b:AE, 5ndg:L6, 5ndg:l6, 5ndv:L6, 5ndv:l6, 5ndw:L6, 5ndw:l6, 5obm:L6, 5obm:l6, 7oh3:E, 7ohp:E, 7ohq:E, 7ohr:E, 7ohs:E, 7oht:E, 7ohu:E, 7ohv:E, 7ohw:E, 7ohx:E, 7ohy:E, 6oig:E, 5on6:n, 5on6:CH, 7osa:eL6, 7osm:eL6, 8p8m:LJ, 8p8n:LJ, 8p8u:LJ, 8pfr:LJ, 6q8y:BM, 6r84:I, 6r86:I, 6r87:I, 6s47:AH, 6sv4:BM, 6sv4:YM, 6sv4:ZM, 5t62:H, 5t6r:H, 6t83:Ha, 5tbw:n, 5tbw:CH, 5tga:L6, 5tga:l6, 5tgm:L6, 5tgm:l6, 7too:AL06, 7top:AL06, 7u0h:E, 4u3m:L6, 4u3m:l6, 4u3n:L6, 4u3n:l6, 4u3u:L6, 4u3u:l6, 4u4n:L6, 4u4n:l6, 4u4o:L6, 4u4o:l6, 4u4q:L6, 4u4q:l6, 4u4r:L6, 4u4r:l6, 4u4u:L6, 4u4u:l6, 4u4y:L6, 4u4y:l6, 4u4z:L6, 4u4z:l6, 4u50:L6, 4u50:l6, 4u51:L6, 4u51:l6, 4u52:L6, 4u52:l6, 4u53:L6, 4u53:l6, 4u55:L6, 4u55:l6, 4u56:L6, 4u56:l6, 4u6f:L6, 4u6f:l6, 7ug6:E, 7uoo:E, 7uqb:E, 7uqz:E, 7v08:E, 4v88:BE, 4v88:DE, 4v8t:E, 4v8y:BE, 4v8z:BE, 8v83:E, 8v84:E, 8v87:E, 4v91:E, 6woo:E, 6xiq:E, 6xir:E, 6ylg:E, 6ylh:E, 6ylx:E, 6yly:E, 5z3g:I, 6z6j:LE, 6z6k:LE, 7zs5:BG
3 6uz7:AE 164 164 0.8387 0.7927 0.7927 2.84e-91 5it7:EE
4 4v6i:BG 176 173 0.8581 0.7557 0.7688 3.96e-90 8aaf:n, 8agt:n, 8agu:n, 8agv:n, 8agw:n, 8agx:n, 8agz:n, 5apn:E, 5apo:E, 7b7d:LH, 8bip:LE, 8bjq:LE, 8bqd:BM, 8bqx:BM, 6c0f:E, 6cb1:E, 8hfr:F8, 5juo:J, 5jup:J, 5jus:J, 5jut:J, 5juu:J, 6n8j:E, 6n8k:E, 6n8l:E, 7nac:E, 7nrc:LH, 7nrd:LH, 7of1:E, 6qik:G, 6qt0:G, 6qtz:G, 7r7a:E, 6ri5:G, 7rr5:LE, 6rzz:G, 6s05:G, 6snt:l, 6t4q:LE, 6t7i:LE, 6t7t:LE, 6t83:Ey, 6tb3:BM, 6tnu:BM, 4v7r:BF, 4v7r:DF, 8y0u:LE, 7z34:E, 7zpq:BE, 7zrs:BE, 7zuw:BE, 7zux:EE, 7zw0:LI
5 8etg:E 145 142 0.6323 0.6759 0.6901 1.88e-63
6 8eui:E 183 175 0.6581 0.5574 0.5829 2.99e-62 8esq:E, 8esr:E, 8etc:E, 8eth:E, 8eti:E, 8etj:E, 8eug:E, 8eup:E, 8euy:E, 8ev3:E
7 7r81:H1 194 170 0.6129 0.4897 0.5588 3.34e-61
8 7olc:LE 194 177 0.6194 0.4948 0.5424 4.23e-59 8i9p:LE, 8i9r:LE, 8i9t:LE, 8i9v:LE, 8i9w:LE, 8i9x:LE, 8i9y:LE, 8i9z:LE, 8ia0:LE, 7old:LE, 8oo0:LE, 8pv1:LE, 8pv2:LE, 8pv3:LE, 8pv4:LE, 8pv5:LE, 8pv6:LE, 8pv7:LE, 8pv8:LE, 8pvk:LE, 8pvl:LE, 7z3n:LE, 7z3o:LE
9 7qiw:H 201 152 0.5677 0.4378 0.5789 6.06e-57 7qiz:H
10 8jiv:CE 175 153 0.5613 0.4971 0.5686 3.13e-55
11 4v3p:LG 219 173 0.5677 0.4018 0.5087 3.23e-53 8ip8:LB, 8ipa:LB, 8ipb:LB, 4v7e:CE
12 4v8p:AE 190 175 0.5613 0.4579 0.4971 8.05e-53 4v8p:DE, 4v8p:FE, 4v8p:HE
13 8azw:b 208 151 0.5355 0.3990 0.5497 3.70e-52 8b2l:b3
14 8q87:BE 225 164 0.5355 0.3689 0.5061 5.08e-44 8q7z:BE
15 4v8m:Bv 157 142 0.4516 0.4459 0.4930 8.99e-43 8ova:Bv, 8ove:Bv
16 7oyc:E1 214 161 0.5161 0.3738 0.4969 1.60e-42
17 8qfd:E 201 160 0.4968 0.3831 0.4813 3.11e-42 8fl0:SC
18 7oya:E1 206 160 0.4774 0.3592 0.4625 9.52e-42 7oyb:E1
19 7zjw:LH 232 167 0.5032 0.3362 0.4671 4.67e-41 7a01:R2, 8a3d:H, 8b5l:E, 8b6c:E, 9bdl:AL06, 9bdn:AL06, 9bdp:AL06, 7bhp:LE, 8bhf:n3, 8bpo:E2, 6d90:E, 6d9j:E, 7f5s:LE, 8fkq:SC, 8fks:SC, 8fkx:SC, 8fky:SC, 8fkz:SC, 8fl2:SC, 8fl3:SC, 8fl4:SC, 8fl6:SC, 8fl7:SC, 8fl9:SC, 8fla:SC, 8flb:SC, 8flc:SC, 8fld:SC, 8fle:SC, 8flf:SC, 9fpz:LE, 9fq0:LE, 8g5y:LE, 8g5z:LE, 8g60:LE, 8g61:LE, 8g6j:LE, 8glp:LE, 6hcf:E3, 6hcj:E3, 6hcm:E3, 6hcq:E3, 8jdj:K, 8jdk:K, 8jdl:K, 8jdm:K, 8k2c:LE, 7ls1:H2, 7ls2:H2, 6lu8:o, 5lzs:E, 5lzt:E, 5lzu:E, 5lzv:E, 5lzw:E, 5lzx:E, 5lzy:E, 5lzz:E, 7mdz:E, 6mtb:E, 6mtc:E, 6mtd:E, 6mte:E, 7nwg:E3, 7nwh:E, 8ohd:LE, 8oj0:LE, 8oj5:LE, 8oj8:LE, 7ow7:H, 7oyd:E, 6p5i:AE, 6p5j:AE, 6p5k:AE, 6p5n:AE, 7qvp:LE, 7qvp:ME, 6r5q:E, 6r6g:E, 6r7q:E, 8rjb:E, 8rjc:E, 8rjd:E, 8scb:E, 6sgc:E2, 6t59:E3, 7toq:AL06, 7tor:AL06, 7ucj:E, 7uck:E, 6w6l:G, 7xnx:LE, 7xny:LE, 8xsy:LE, 8xsz:LE, 6y0g:LE, 8y0x:LE, 6y2l:LE, 6y57:LE, 8yoo:LE, 8yop:LE, 6zvk:R2
20 5xxb:E 124 129 0.4774 0.5968 0.5736 3.91e-39
21 4v6x:CE 262 177 0.4968 0.2939 0.4350 9.92e-39 7a01:T2, 5aj0:AE, 8btk:BE, 7cpu:LE, 7cpv:LE, 4d5y:E, 4d67:E, 9f1b:BE, 9f1c:BE, 9f1d:BE, 8fku:SC, 8fkw:SC, 6frk:E, 6ftg:E, 6fti:E, 6ftj:E, 6gz3:AE, 6gz4:AE, 6gz5:AE, 8idt:o, 8idy:o, 8ie3:o, 8ifd:1H, 8ife:1H, 8ine:o, 8inf:o, 8ink:o, 6ip5:1H, 6ip6:1H, 6ip8:1H, 8ipd:o, 8ipx:o, 8ipy:o, 8ir1:o, 8ir3:o, 3j7o:E, 3j7p:E, 3j7q:E, 3j7r:E, 3j92:E, 3jag:E, 3jah:E, 3jai:E, 3jaj:E, 3jan:E, 5lks:LE, 6lqm:v, 6lsr:v, 6lss:o, 7nfx:E, 7nwi:E, 7o7y:BE, 7o7z:BE, 7o80:BE, 7o81:BE, 7obr:E, 6ole:G, 6olf:G, 6olg:AE, 6oli:G, 6olz:AE, 6om0:G, 6om7:G, 8p2k:BE, 7qgg:G, 8qoi:LE, 7qwq:E, 7qwr:E, 7qws:E, 6qzp:LE, 6r6p:E, 6swa:E, 5t2c:H, 7tm3:E, 7tut:E, 4ug0:LE, 4ujc:BE, 4ujd:AE, 4uje:CE, 6xa1:LE, 8xsx:LE, 8y0w:LE, 6y6x:LE, 6z6l:LE, 6z6m:LE, 6z6n:LE, 7zjx:LH, 6zm7:LE, 6zme:LE, 6zmi:LE, 6zmo:LE, 6zvk:T2
22 8fkp:SC 199 172 0.4710 0.3668 0.4244 6.81e-38 8fkr:SC, 8fkt:SC, 8fkv:SC
23 5t5h:v 132 133 0.4323 0.5076 0.5038 7.35e-38
24 8rxh:LF 149 145 0.4581 0.4765 0.4897 9.65e-38 8a3w:F, 8a98:F, 6az3:F, 3jcs:F, 8ovj:F, 8rxx:LF, 5t2a:t
25 9bh5:CE 139 135 0.4581 0.5108 0.5259 1.56e-37 9cai:CE
26 6zj3:LU 194 183 0.4258 0.3402 0.3607 2.95e-30
27 4v6w:CE 228 152 0.4387 0.2982 0.4474 4.25e-30 6xu6:CE, 6xu7:CE, 6xu8:CE
28 6zu5:LE0 179 161 0.3161 0.2737 0.3043 6.31e-20
29 3j79:I 207 183 0.3484 0.2609 0.2951 1.17e-15 3jbn:AI, 3jbo:AI, 3jbp:AI, 8tpu:AI, 5umd:I
30 8p5d:LE0 165 155 0.2903 0.2727 0.2903 2.50e-14 8p60:LE0, 8p60:KE0, 7qca:LE0
31 5xy3:E 135 134 0.2710 0.3111 0.3134 7.25e-11
32 8hku:L141 86 58 0.1355 0.2442 0.3621 1.70e-06 8hku:L142, 8hkv:L141, 8hkv:L142, 8hky:L141, 8hky:L142, 8hkz:L141, 8hkz:L142, 8hl1:L141, 8hl1:L142, 8hl2:L141, 8hl2:L142, 8hl3:L141, 8hl3:L142, 8hl4:L141, 8hl4:L142, 8hl5:L141, 8hl5:L142
33 6rm3:LZ0 125 125 0.2000 0.2480 0.2480 7.70e-04
34 4d5y:Z 136 29 0.0839 0.0956 0.4483 0.003 7a01:22, 8a3d:T, 5aj0:AZ, 8b5l:Z, 8b6c:Z, 9bdl:AL27, 9bdn:AL27, 9bdp:AL27, 7bhp:LZ, 8bhf:M1, 8bpo:Y2, 8btk:BZ, 7cpu:LZ, 7cpv:LZ, 4d67:Z, 6d90:Z, 6d9j:Z, 9f1b:BZ, 9f1c:BZ, 9f1d:BZ, 7f5s:LZ, 8fky:LJ, 8fkz:LJ, 8fl2:LJ, 8fl3:LJ, 8fl4:LJ, 8fl6:LJ, 8fl7:LJ, 8fl9:LJ, 8fla:LJ, 8flb:LJ, 8flc:LJ, 8fld:LJ, 8fle:LJ, 8flf:LJ, 6frk:Z, 6ftg:Z, 6fti:Z, 6ftj:Z, 8g5y:LZ, 8g5z:LZ, 8g60:LZ, 8g61:LZ, 8g6j:LZ, 8glp:LZ, 6gz3:AZ, 6gz4:AZ, 6gz5:AZ, 6hcf:Z3, 6hcj:Z3, 6hcm:Z3, 6hcq:Z3, 8idt:i, 8idy:i, 8ie3:i, 8ifd:2T, 8ife:2T, 8ine:i, 8inf:i, 8ink:i, 6ip5:2T, 6ip6:2T, 6ip8:2T, 8ipd:i, 8ipx:i, 8ipy:i, 8ir1:i, 8ir3:i, 3j7o:Z, 3j7p:Z, 3j7q:Z, 3j7r:Z, 3j92:Z, 3jag:Z, 3jah:Z, 3jai:Z, 3jaj:Z, 3jan:Z, 8jdj:e, 8jdk:e, 8jdl:e, 8jdm:e, 8k2c:LZ, 5lks:LZ, 6lqm:i, 6lsr:i, 6lss:i, 7ls1:T2, 7ls2:T2, 6lu8:i, 5lzs:Z, 5lzt:Z, 5lzu:Z, 5lzv:Z, 5lzw:Z, 5lzx:Z, 5lzy:Z, 5lzz:Z, 7mdz:Z, 6mtb:Z, 6mtc:Z, 6mtd:Z, 6mte:Z, 7nfx:Z, 7nwg:Z3, 7nwh:Z, 7nwi:Z, 7o7y:BZ, 7o7z:BZ, 7o80:BZ, 7o81:BZ, 7obr:Z, 8ohd:LZ, 8oj0:LZ, 8oj5:LZ, 8oj8:LZ, 6ole:a, 6olf:a, 6olg:AZ, 6oli:a, 6olz:AZ, 6om0:a, 6om7:a, 7ow7:T, 7oya:Z1, 7oyb:Z1, 7oyc:Z1, 7oyd:Z, 8p2k:BZ, 6p5i:AZ, 6p5j:AZ, 6p5k:AZ, 6p5n:AZ, 8q7z:BZ, 8q87:BZ, 8qfd:Z, 7qgg:a, 8qoi:LZ, 7qvp:LZ, 7qvp:MZ, 7qwq:Z, 7qwr:Z, 7qws:Z, 6qzp:LZ, 6r5q:Z, 6r6g:Z, 6r6p:Z, 6r7q:Z, 8rjb:Z, 8rjc:Z, 8rjd:Z, 8scb:Z, 6sgc:Z2, 6swa:X, 5t2c:T, 6t59:Z3, 7tm3:Z, 7toq:AL27, 7tor:AL27, 7tut:Z, 7ucj:Z, 7uck:Z, 4ug0:LZ, 4ujc:BZ, 4ujd:AZ, 4uje:CZ, 4v6x:CZ, 6w6l:a, 6xa1:LZ, 7xnx:LZ, 7xny:LZ, 8xsx:LZ, 8xsy:LZ, 8xsz:LZ, 6y0g:LZ, 8y0w:LZ, 8y0x:LZ, 6y2l:LZ, 6y57:LZ, 6y6x:LZ, 8yoo:LZ, 8yop:LZ, 6z6l:LZ, 6z6m:LZ, 6z6n:LZ, 7zjw:Lc, 7zjx:Lc, 6zm7:LZ, 6zme:LZ, 6zmi:LZ, 6zmo:LZ, 6zvk:22
35 4v4n:A5 81 57 0.1097 0.2099 0.2982 0.023 4v4n:AK, 4v6u:B5, 4v6u:BK
36 6skf:BM 81 78 0.1484 0.2840 0.2949 0.032 6skf:BN, 6skg:BM, 6skg:BN, 6th6:BM, 6th6:BN
37 4v8p:AN 143 26 0.0968 0.1049 0.5769 0.032 4v8p:DN, 4v8p:FN, 4v8p:HN
38 8ip8:CA 136 29 0.0839 0.0956 0.4483 0.17 8ipa:CA, 8ipb:CA, 8jiv:CZ, 4v3p:La, 4v7e:CZ
39 7qep:N7 118 104 0.1419 0.1864 0.2115 0.28
40 6zu5:LZ0 127 35 0.1032 0.1260 0.4571 0.68
41 3e1t:A 437 38 0.0968 0.0343 0.3947 0.81
42 3j79:1 140 50 0.1290 0.1429 0.4000 0.86 3jbn:A1, 3jbo:A1, 3jbp:A1, 8tpu:A1, 5umd:1
43 8esq:Z 134 36 0.0968 0.1119 0.4167 0.92 8esr:Z, 8etc:Z, 8eug:Z, 8eui:Z
44 5t5h:a 105 29 0.0710 0.1048 0.3793 1.4
45 8ova:Ba 132 26 0.0710 0.0833 0.4231 1.5 8ove:Ba, 4v8m:Ba
46 4v6w:CZ 134 32 0.0645 0.0746 0.3125 1.6 6xu6:CZ, 6xu7:CZ, 6xu8:CZ
47 8cd1:U 103 28 0.0839 0.1262 0.4643 1.7 6spb:U, 6spd:U, 6spf:U, 6spg:U, 7unr:W, 7unu:W, 7unv:W, 7unw:W
48 5e7g:A 446 118 0.1613 0.0561 0.2119 2.6
49 8fru:Z 134 26 0.0774 0.0896 0.4615 3.5 8brm:La, 8bsi:La, 8bsj:La, 8btd:La, 8btr:La, 7pwg:Z, 7pwo:Z2
50 8c3a:AA 135 33 0.0903 0.1037 0.4242 3.6 8c3a:BU, 8cq7:AA, 8cq7:BU, 8cqw:AA, 8cqw:BU, 8cre:AA, 8cre:BU, 8oeq:AA, 8oeq:BU, 7pzy:AA, 7q08:AA, 7q0f:AA, 7q0p:AA, 7q0r:AA, 8q5i:AA
51 8br8:La 119 26 0.0774 0.1008 0.4615 3.8
52 7pfs:A 916 71 0.1355 0.0229 0.2958 4.6 5ab0:A, 5ab2:A, 5j6s:A, 5k1v:A, 7nsk:A, 7nup:A, 7nup:B, 7p7p:A, 7sh0:A
53 7nup:D 884 71 0.1355 0.0238 0.2958 4.9 5ab0:C, 5ab2:B, 4e36:A, 4e36:B, 6ea4:A, 6ea4:B, 5j6s:B, 4jbs:A, 4jbs:B, 7nsk:B, 7nup:C, 7p7p:B, 7pfs:B, 3se6:A, 3se6:B
54 5k1v:B 849 71 0.1355 0.0247 0.2958 5.0 7sh0:B
55 8rxh:LY 133 24 0.0710 0.0827 0.4583 5.0 8a3w:Y, 8a98:Y, 6az3:Y, 3jcs:Y, 8ovj:Y, 8rxx:LY, 5t2a:Y
56 4o98:B 307 56 0.1097 0.0554 0.3036 8.2 4o98:A
57 7bam:A 1904 85 0.1548 0.0126 0.2824 8.9 7bam:B, 7ban:A, 7ban:B, 7bao:A, 7plp:A, 7plp:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218