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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
QSVSIVGIASRCAPHKLGADELEAIARRHYSSTPSLEKMLEINRKTRIDHRYSVFSSDHEHWHRPTIPSFSECDSLFKEY
GIPLASAASARAIQDWGGVPDEITHLVAVTCTNTAHPGFDSVLCRKLGLKCNVRRVLLHGIGCGGGISAMRVAHELLLGS
TQQGVPARALIVACEVPTVFARSELDIMDKTQDVNVAMCLFGDCAAALVLSNGIGHKASEQRPIWNILNCEPTQFDGTED
IAHFNVHDKGYHAIIDKRIPQLTGKCVPAGFQSLISSTPSLALEEKNYVPSNYGWAVHPGGYAVLVAAQDALGLTADDLR
ASYDAYRDGGNTISTTIIRILEKLRDEHKHGSNQKDKLVLAAWGHGITLETAILTRP

The query sequence (length=377) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 3wy0:B 377 377 1.0000 1.0000 1.0000 0.0 3wxy:A, 3wxy:B, 3wy0:A
2 3eut:A 379 378 0.3846 0.3826 0.3836 3.21e-91 3eut:C
3 1ee0:A 376 349 0.2891 0.2899 0.3123 7.91e-36 1ee0:B
4 7f08:J 379 298 0.2467 0.2454 0.3121 3.67e-33 7f08:B, 7f08:D, 7f08:L
5 2d3m:A 405 387 0.2918 0.2716 0.2842 2.50e-32 2d3m:B, 2d52:A, 2d52:B
6 5wx6:B 376 348 0.2467 0.2473 0.2672 8.76e-30 5wx3:A, 5wx3:B, 5wx3:D, 5wx6:A, 5wx6:C, 5wx6:D, 5wx7:A, 5wx7:B, 5wx7:C, 5wx7:D
7 3wd7:A 401 298 0.2308 0.2170 0.2919 2.49e-29 7cct:A, 6l7j:A, 3wd7:B
8 6j1m:A 381 350 0.2706 0.2677 0.2914 2.53e-29 6j1m:B, 6j1n:A, 6j1n:B
9 6op5:A 383 296 0.2308 0.2272 0.2939 6.94e-29 6op5:B
10 5w8q:A 379 296 0.2149 0.2137 0.2736 1.39e-28 5w8q:B, 5wc4:A, 5wc4:B
11 3awj:A 380 296 0.2361 0.2342 0.3007 1.10e-27
12 6gw3:A 383 301 0.2175 0.2141 0.2724 2.88e-27 6gw3:B, 6gw3:C, 6gw3:D, 7w6g:C, 7w6g:D
13 7bur:B 389 348 0.2414 0.2339 0.2615 3.25e-27 7bur:A, 8jrd:A, 8jrd:B
14 5wx3:C 353 312 0.2175 0.2323 0.2628 7.41e-27
15 8v8m:A 389 347 0.2414 0.2339 0.2622 1.48e-25 8v8m:C
16 1chw:A 389 296 0.2149 0.2082 0.2736 4.04e-25 1bq6:A, 1cgk:A, 1cgz:A, 1chw:B, 1cml:A, 1d6h:A, 1u0w:A, 1u0w:B, 1u0w:C, 1u0w:D
17 1z1f:A 388 350 0.2308 0.2242 0.2486 5.33e-24
18 7d41:A 367 375 0.2546 0.2616 0.2560 2.78e-23 7d41:B
19 4b0n:A 379 273 0.1963 0.1953 0.2711 5.73e-22 4b0n:B
20 8b3c:B 383 300 0.2228 0.2193 0.2800 6.71e-22 8b32:A, 8b32:B, 8b35:A, 8b35:B, 8b3c:A
21 7vf0:B 396 295 0.2414 0.2298 0.3085 8.69e-22 7vez:A, 7vez:B, 7vez:C, 7vez:D, 7vf0:A, 7vf0:C, 7vf0:D
22 7yj6:A 390 266 0.2016 0.1949 0.2857 1.35e-21 7yj5:A, 7yj6:B, 7yj7:A, 7yj8:A, 7yj9:A, 7yja:A, 7yja:B, 7yjb:A
23 1xes:A 387 351 0.2440 0.2377 0.2621 4.82e-19 1xes:B, 1xes:C, 1xes:D, 1xet:B, 1xet:C, 1xet:D
24 4jap:C 353 377 0.2414 0.2578 0.2414 9.90e-19 4jao:C, 4jao:B, 4jap:B, 4jap:A, 4jaq:D, 4jaq:A, 4jaq:C, 4jaq:B, 4jd3:C, 4jd3:B
25 6skf:Aj 129 50 0.0371 0.1085 0.2800 0.98 6skg:Aj, 6sw9:I, 6swc:I, 6swd:I, 6th6:Aj, 6tmf:J, 7zag:I, 7zah:I, 7zai:I, 7zhg:I
26 1mzj:A 334 142 0.1088 0.1228 0.2887 2.4 1mzj:B
27 4y28:G 91 76 0.0584 0.2418 0.2895 4.4
28 8iuf:V1 504 74 0.0610 0.0456 0.3108 5.0 8j9h:V1, 8j9i:V1, 8j9j:V1
29 3kvo:B 276 72 0.0584 0.0797 0.3056 5.2 3kvo:A
30 7x2y:A 342 156 0.0981 0.1082 0.2372 6.6 7x1x:A, 7x1x:B, 7x2y:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218