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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
QPKLLNCQLKEYQLKGLNWLVNLYEQGINGILADEMGLGKTVQSISVMAYLAERYDIWGPFLVVAPASTLHNWQQEVSKF
VPDFKVLPYWGTAADRKVLRKFWDRKHTTYKKDSPFHVMITSYQLVVSDVAYFQKMKWQYMILDEAQAIKSSQSSRWKCL
LGFHCRNRLLLTGTPIQNNMQELWALLHFIMPSLFDSQLKRLHMILKPFMLRRVKKHVQKELGDKIEIDVFCELSYRQRA
MYQSLRNQISIMDTLMNLVMQFRKVCNHPDLFERAPSMARFVTDSGKLAKLDELLRELKEGGHRVLLYFQMTRMIDLMEE
YLTYRNYKYCRLDGSTKLEDRRDTVADFQTRPEIFIFLLSTRAGGLGINLTTADTVIFYDSDWNPTIDSQAMDRAHRLGQ
TKQVTVYRLITRGTIEERIRKRALQKEEVQRVVITGTGS

The query sequence (length=439) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8atf:G 442 447 0.9727 0.9661 0.9553 0.0 8oo9:G, 8oos:G
2 8oo7:G 704 297 0.6401 0.3991 0.9461 0.0 8oop:G
3 8oo7:G 704 164 0.3736 0.2330 1.0000 9.11e-109 8oop:G
4 6fml:G 731 326 0.6401 0.3844 0.8620 0.0 8av6:G
5 6fml:G 731 162 0.3690 0.2216 1.0000 3.99e-107 8av6:G
6 6pwf:K 454 458 0.4989 0.4824 0.4782 1.30e-143
7 6ne3:W 461 459 0.4806 0.4577 0.4597 3.01e-141 8v4y:W, 8v6v:W, 8v6v:X, 8v7l:W
8 7zi4:G 682 282 0.4328 0.2786 0.6738 1.21e-132
9 7zi4:G 682 164 0.2688 0.1730 0.7195 7.87e-75
10 7x3t:V 792 461 0.4715 0.2614 0.4490 2.84e-128 6iro:L, 6jyl:K, 6k1p:K, 7x3w:K, 2y9z:A
11 6uxw:A 778 471 0.4601 0.2596 0.4289 9.65e-125 7egp:A, 6iy2:O, 6iy3:O, 6uxv:A, 5x0x:O, 5x0y:O, 5z3l:O, 5z3o:O, 5z3u:O, 5z3v:O
12 7y8r:I 732 457 0.4533 0.2719 0.4354 1.07e-124
13 6vz4:K 616 465 0.4670 0.3328 0.4409 1.25e-124 6kw3:Y, 6kw4:Y, 6kw5:Q
14 6tda:S 783 461 0.4670 0.2618 0.4447 1.06e-123
15 8kcc:K 508 455 0.4442 0.3839 0.4286 1.67e-120 8j90:K, 8kcb:K, 8wh5:K, 8wh8:K, 8wh9:K, 8wha:K, 8wha:L
16 7vdv:A 809 484 0.4556 0.2472 0.4132 1.02e-119 7vdt:A
17 7ux9:P 468 478 0.4396 0.4124 0.4038 5.68e-113
18 6ftx:W 878 458 0.4260 0.2130 0.4083 1.97e-111 6g0l:W, 5j70:A, 5j70:B, 3mwy:W, 3ted:A
19 6g0l:M 855 448 0.4282 0.2199 0.4196 1.11e-110 7nkx:W, 5o9g:W
20 6ryr:W 708 489 0.4715 0.2924 0.4233 1.17e-110 2l75:A, 1mm2:A, 6q3m:D, 6ryu:W, 6ryu:V
21 9gd1:W 849 472 0.4237 0.2191 0.3941 1.52e-109
22 7tn2:W 895 480 0.4282 0.2101 0.3917 1.87e-109 9gd2:W, 9gd3:W
23 7epu:B 748 461 0.4214 0.2473 0.4013 1.26e-108 8b0a:K, 7enn:K, 7otq:K
24 5hzr:A 552 452 0.4055 0.3225 0.3938 7.80e-102
25 6gej:M 688 301 0.3280 0.2093 0.4784 3.15e-90 6gen:M
26 6gej:M 688 159 0.1913 0.1221 0.5283 1.76e-50 6gen:M
27 7xyf:K 656 522 0.4123 0.2759 0.3467 3.67e-90 7xyg:K
28 8b3f:b 534 472 0.3759 0.3090 0.3496 4.89e-88 8b3d:b, 7oo3:b, 7oob:b, 7oop:b, 7opc:b, 7opd:b
29 8x19:I 864 315 0.3235 0.1644 0.4508 7.33e-88 8x1c:I
30 8x19:I 864 174 0.2096 0.1065 0.5287 1.54e-51 8x1c:I
31 7z8s:E 1514 464 0.3622 0.1050 0.3427 3.55e-81 7zb5:E, 7zb5:H
32 7zke:E 1623 497 0.3781 0.1023 0.3340 7.25e-81
33 8he5:O 516 468 0.3736 0.3178 0.3504 1.52e-79
34 8tvy:M 558 476 0.3690 0.2903 0.3403 3.04e-79 5vvr:M
35 1z63:A 468 450 0.3212 0.3013 0.3133 6.68e-73 1z63:B
36 8x15:I 792 290 0.2825 0.1566 0.4276 3.52e-72
37 8x15:I 792 164 0.1959 0.1086 0.5244 2.75e-45
38 5jxt:M 324 229 0.2574 0.3488 0.4934 6.28e-66 5jxt:N, 5jxt:O, 5jxt:J, 5jxt:K, 5jxt:I, 5jxt:H
39 8eu9:Q 426 152 0.2323 0.2394 0.6711 2.61e-57 8ets:Q, 8etu:Q, 8euf:Q
40 8eu9:Q 426 156 0.1298 0.1338 0.3654 1.92e-14 8ets:Q, 8etu:Q, 8euf:Q
41 1z3i:X 644 500 0.3280 0.2236 0.2880 1.53e-52
42 6eg2:A 619 245 0.2141 0.1519 0.3837 1.79e-50 6eg3:A
43 7z7n:E 1306 231 0.1731 0.0582 0.3290 8.40e-36
44 9c57:G 878 280 0.1913 0.0957 0.3000 3.93e-35
45 9c57:G 878 187 0.1549 0.0774 0.3636 9.85e-28
46 6l8n:A 810 152 0.1071 0.0580 0.3092 9.42e-15
47 6l8n:A 810 314 0.1868 0.1012 0.2611 1.86e-14
48 7r78:A 1880 171 0.1116 0.0261 0.2865 4.78e-06
49 7r78:A 1880 144 0.0752 0.0176 0.2292 0.039
50 6rfl:Y 600 425 0.2005 0.1467 0.2071 7.29e-06 7aoh:Y, 8c8h:Y
51 8sp4:A 859 186 0.1048 0.0536 0.2473 1.54e-05 8spg:A
52 8sp4:A 859 50 0.0319 0.0163 0.2800 1.1 8spg:A
53 7r76:A 1834 138 0.0934 0.0224 0.2971 2.49e-05 7r77:A
54 7r76:A 1834 144 0.0752 0.0180 0.2292 0.037 7r77:A
55 7t02:A 1752 138 0.0866 0.0217 0.2754 0.013
56 8ebu:A 604 201 0.1002 0.0728 0.2189 0.028 8ebt:A, 8ebx:A, 8eby:A
57 7lbm:W 574 202 0.1002 0.0767 0.2178 0.030
58 7ena:6 652 201 0.1002 0.0675 0.2189 0.035 7ad8:A, 8bvw:0, 8ebs:A, 8ebv:A, 8ebw:A, 7egb:6, 7egc:6, 7enc:6, 8gxq:HH, 8gxs:HH, 5ivw:V, 5iy6:V, 5iy7:V, 5iy8:V, 5iy9:V, 7nvr:7, 7nvv:7, 7nvw:7, 7nvx:7, 7nvy:7, 7nvz:7, 7nw0:7, 6o9l:7, 6ro4:A, 8wak:6, 8wal:6, 8wan:6, 8wao:6, 8wap:6, 8waq:6, 8war:6, 8was:6
59 8y6o:I 597 97 0.0501 0.0369 0.2268 0.17 8qp8:G, 6qw6:5X, 6qx9:5X, 8r08:G
60 6vtv:B 252 160 0.1002 0.1746 0.2750 0.36 6vtv:A
61 3meb:A 426 53 0.0456 0.0469 0.3774 0.61 3meb:B
62 7uhy:A 771 69 0.0456 0.0259 0.2899 3.2 7uhy:B
63 2wjy:A 773 73 0.0501 0.0285 0.3014 3.8 2gjk:A, 2gk6:A, 2gk6:B, 2gk7:A, 8rxb:E, 8rxb:A, 8rxb:D, 8rxb:I, 8rxb:L, 8rxb:P, 2wjv:A, 2wjv:B, 2xzo:A
64 2yy7:A 312 75 0.0433 0.0609 0.2533 4.3 2yy7:B
65 3rc8:A 610 43 0.0387 0.0279 0.3953 4.6 3rc3:A
66 2a3z:B 260 59 0.0364 0.0615 0.2712 4.7 2a40:B, 2a40:E, 2a41:B, 2a42:B, 1atn:D, 2d1k:B, 1dnk:A, 2dnj:A, 3dni:A, 9fju:E, 9fjy:E, 9fjy:F, 7nxv:B, 7nxv:F, 3w3d:B
67 4rk9:A 384 103 0.0592 0.0677 0.2524 5.1 4rk9:B
68 5ffj:A 1044 190 0.0934 0.0393 0.2158 7.8
69 4xqk:A 1517 195 0.0934 0.0270 0.2103 7.9 4xqk:B
70 5koh:B 510 56 0.0478 0.0412 0.3750 8.8 5koh:D, 5koj:B, 5koj:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218