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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
QPKLLNCQLKEYQLKGLNWLVNLYEQGINGILADEMGLGKTVQSISVMAYLAERYDIWGPFLVVAPASTLHNWQQEVSKF
VPDFKVLPYWGTAADRKVLRKFWDRKHTTYKKDSPFHVMITSYQLVVSDVAYFQKMKWQYMILDEAQAIKSSQSSRWKCL
LGFHCRNRLLLTGTPIQNNMQELWALLHFIMPSLFDSQLKRLHMILKPFMLRRVKKHVQKELGDKIEIDVFCELSYRQRA
MYQSLRNQISIMDTLMNLVMQFRKVCNHPDLFERADTSSPFFCGHFAETGSFLREGTNVALGYSTRSLVEYRLPRLIWCD
GGRLDKPGPGNLVAGFRSKYLNHMMNIWTPENIRSSLEGIENFTWLRFVDTSLQEAYRASHTDVFARAVDLASKQNRLGH
MQIVYDEPEDKKWTPVHALFQICERENPKAVAEITTEGVLRDLMNIARVKYRELGLCRLEKAARPRASAPPIEVVCDSRS
AVIERENIMFHPAMRKALFGPTPSEIKEASFGPRPVTLYPPRALLPAPDHDKQRFTNITVPSMARFVTDSGKLAKLDELL
RELKEGGHRVLLYFQMTRMIDLMEEYLTYRNYKYCRLDGSTKLEDRRDTVADFQTRPEIFIFLLSTRAGGLGINLTTADT
VIFYDSDWNPTIDSQAMDRAHRLGQTKQVTVYRLITRGTIEERIRKRALQKEEVQRVVITGTGS

The query sequence (length=704) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8oo7:G 704 704 1.0000 1.0000 1.0000 0.0 8oop:G
2 6fml:G 731 731 0.9972 0.9603 0.9603 0.0 8av6:G
3 7zi4:G 682 735 0.5170 0.5337 0.4952 0.0
4 8atf:G 442 328 0.3963 0.6312 0.8506 0.0 8oo9:G, 8oos:G
5 8atf:G 442 162 0.2301 0.3665 1.0000 1.41e-106 8oo9:G, 8oos:G
6 8eu9:Q 426 484 0.2898 0.4789 0.4215 4.16e-101 8ets:Q, 8etu:Q, 8euf:Q
7 8x19:I 864 332 0.2088 0.1701 0.4428 1.34e-85 8x1c:I
8 8x19:I 864 161 0.1236 0.1007 0.5404 1.02e-48 8x1c:I
9 6gej:M 688 304 0.2031 0.2078 0.4704 5.84e-85 6gen:M
10 6gej:M 688 172 0.1250 0.1279 0.5116 4.89e-50 6gen:M
11 6pwf:K 454 297 0.1832 0.2841 0.4343 2.95e-73
12 6pwf:K 454 156 0.1264 0.1960 0.5705 1.62e-51
13 6ne3:W 461 309 0.1776 0.2711 0.4045 1.10e-71 8v4y:W, 8v6v:W, 8v6v:X, 8v7l:W
14 6ne3:W 461 155 0.1264 0.1931 0.5742 8.05e-52 8v4y:W, 8v6v:W, 8v6v:X, 8v7l:W
15 8x15:I 792 307 0.1832 0.1629 0.4202 2.11e-70
16 8x15:I 792 151 0.1151 0.1023 0.5364 7.96e-43
17 7y8r:I 732 300 0.1719 0.1653 0.4033 2.60e-68
18 7y8r:I 732 153 0.1151 0.1107 0.5294 9.94e-40
19 7x3t:V 792 301 0.1719 0.1528 0.4020 3.00e-67 6iro:L, 6jyl:K, 6k1p:K, 7x3w:K, 2y9z:A
20 7x3t:V 792 136 0.1094 0.0972 0.5662 6.15e-44 6iro:L, 6jyl:K, 6k1p:K, 7x3w:K, 2y9z:A
21 7vdv:A 809 348 0.1804 0.1570 0.3649 3.73e-67 7vdt:A
22 7vdv:A 809 153 0.1151 0.1001 0.5294 9.91e-40 7vdt:A
23 6uxw:A 778 302 0.1719 0.1555 0.4007 1.22e-66 7egp:A, 6iy2:O, 6iy3:O, 6uxv:A, 5x0x:O, 5x0y:O, 5z3l:O, 5z3o:O, 5z3u:O, 5z3v:O
24 6uxw:A 778 153 0.1122 0.1015 0.5163 1.26e-40 7egp:A, 6iy2:O, 6iy3:O, 6uxv:A, 5x0x:O, 5x0y:O, 5z3l:O, 5z3o:O, 5z3u:O, 5z3v:O
25 6vz4:K 616 298 0.1747 0.1997 0.4128 8.49e-64 6kw3:Y, 6kw4:Y, 6kw5:Q
26 6vz4:K 616 151 0.1136 0.1299 0.5298 1.49e-42 6kw3:Y, 6kw4:Y, 6kw5:Q
27 6tda:S 783 294 0.1747 0.1571 0.4184 2.05e-63
28 6tda:S 783 151 0.1136 0.1022 0.5298 4.18e-42
29 5hzr:A 552 301 0.1634 0.2083 0.3821 2.76e-62
30 5hzr:A 552 136 0.0866 0.1105 0.4485 6.62e-25
31 8kcc:K 508 309 0.1676 0.2323 0.3819 9.65e-62 8j90:K, 8kcb:K, 8wh5:K, 8wh8:K, 8wh9:K, 8wha:K, 8wha:L
32 8kcc:K 508 159 0.1151 0.1594 0.5094 7.86e-41 8j90:K, 8kcb:K, 8wh5:K, 8wh8:K, 8wh9:K, 8wha:K, 8wha:L
33 6ryr:W 708 323 0.1761 0.1751 0.3839 2.96e-55 2l75:A, 1mm2:A, 6q3m:D, 6ryu:W, 6ryu:V
34 6ryr:W 708 136 0.1037 0.1031 0.5368 8.30e-39 2l75:A, 1mm2:A, 6q3m:D, 6ryu:W, 6ryu:V
35 6ftx:W 878 294 0.1548 0.1241 0.3707 6.53e-55 6g0l:W, 5j70:A, 5j70:B, 3mwy:W, 3ted:A
36 6ftx:W 878 147 0.1065 0.0854 0.5102 5.12e-40 6g0l:W, 5j70:A, 5j70:B, 3mwy:W, 3ted:A
37 7epu:B 748 317 0.1577 0.1484 0.3502 3.10e-54 8b0a:K, 7enn:K, 7otq:K
38 7epu:B 748 149 0.1108 0.1043 0.5235 5.18e-38 8b0a:K, 7enn:K, 7otq:K
39 6g0l:M 855 284 0.1562 0.1287 0.3873 3.84e-54 7nkx:W, 5o9g:W
40 6g0l:M 855 147 0.1065 0.0877 0.5102 4.51e-40 7nkx:W, 5o9g:W
41 7ux9:P 468 331 0.1634 0.2457 0.3474 3.87e-54
42 7ux9:P 468 160 0.1165 0.1752 0.5125 1.01e-41
43 7tn2:W 895 303 0.1548 0.1218 0.3597 1.24e-53 9gd2:W, 9gd3:W
44 7tn2:W 895 156 0.1080 0.0849 0.4872 2.20e-40 9gd2:W, 9gd3:W
45 9gd1:W 849 296 0.1520 0.1260 0.3615 1.28e-53
46 9gd1:W 849 155 0.1080 0.0895 0.4903 3.47e-40
47 5jxt:M 324 156 0.1222 0.2654 0.5513 3.00e-52 5jxt:N, 5jxt:O, 5jxt:J, 5jxt:K, 5jxt:I, 5jxt:H
48 5jxt:M 324 68 0.0369 0.0802 0.3824 2.33e-04 5jxt:N, 5jxt:O, 5jxt:J, 5jxt:K, 5jxt:I, 5jxt:H
49 6eg2:A 619 245 0.1335 0.1519 0.3837 1.04e-48 6eg3:A
50 7xyf:K 656 316 0.1591 0.1707 0.3544 2.95e-48 7xyg:K
51 7xyf:K 656 140 0.0923 0.0991 0.4643 8.52e-33 7xyg:K
52 1z63:A 468 379 0.1477 0.2222 0.2744 7.72e-42 1z63:B
53 1z63:A 468 156 0.0739 0.1111 0.3333 6.98e-19 1z63:B
54 7zke:E 1623 324 0.1364 0.0591 0.2963 2.18e-39
55 7zke:E 1623 120 0.0881 0.0382 0.5167 3.89e-31
56 7z8s:E 1514 307 0.1293 0.0601 0.2964 5.28e-39 7zb5:E, 7zb5:H
57 7z8s:E 1514 138 0.0966 0.0449 0.4928 1.05e-31 7zb5:E, 7zb5:H
58 8b3f:b 534 143 0.0966 0.1273 0.4755 4.16e-37 8b3d:b, 7oo3:b, 7oob:b, 7oop:b, 7opc:b, 7opd:b
59 8b3f:b 534 317 0.1378 0.1816 0.3060 1.72e-35 8b3d:b, 7oo3:b, 7oob:b, 7oop:b, 7opc:b, 7opd:b
60 8tvy:M 558 303 0.1378 0.1738 0.3201 4.86e-37 5vvr:M
61 8tvy:M 558 157 0.0881 0.1111 0.3949 2.99e-29 5vvr:M
62 9c57:G 878 351 0.1392 0.1116 0.2792 6.62e-35
63 9c57:G 878 206 0.0994 0.0797 0.3398 2.15e-27
64 7z7n:E 1306 231 0.1080 0.0582 0.3290 4.32e-34
65 8he5:O 516 295 0.1349 0.1841 0.3220 2.26e-33
66 8he5:O 516 156 0.0966 0.1318 0.4359 8.05e-33
67 1z3i:X 644 153 0.0881 0.0963 0.4052 1.54e-25
68 1z3i:X 644 329 0.1179 0.1289 0.2523 3.02e-20
69 6l8n:A 810 152 0.0668 0.0580 0.3092 1.88e-14
70 6l8n:A 810 307 0.1136 0.0988 0.2606 2.32e-13
71 7r78:A 1880 234 0.0838 0.0314 0.2521 4.56e-06
72 7r78:A 1880 144 0.0469 0.0176 0.2292 0.049
73 7r76:A 1834 140 0.0597 0.0229 0.3000 3.68e-05 7r77:A
74 7r76:A 1834 144 0.0469 0.0180 0.2292 0.053 7r77:A
75 8sp4:A 859 186 0.0653 0.0536 0.2473 4.40e-05 8spg:A
76 8sp4:A 859 50 0.0199 0.0163 0.2800 1.7 8spg:A
77 6rfl:Y 600 178 0.0497 0.0583 0.1966 0.002 7aoh:Y, 8c8h:Y
78 6rfl:Y 600 84 0.0298 0.0350 0.2500 7.7 7aoh:Y, 8c8h:Y
79 7t02:A 1752 204 0.0682 0.0274 0.2353 0.008
80 7ena:6 652 207 0.0639 0.0690 0.2174 0.059 7ad8:A, 8bvw:0, 8ebs:A, 8ebv:A, 8ebw:A, 7egb:6, 7egc:6, 7enc:6, 8gxq:HH, 8gxs:HH, 5ivw:V, 5iy6:V, 5iy7:V, 5iy8:V, 5iy9:V, 7nvr:7, 7nvv:7, 7nvw:7, 7nvx:7, 7nvy:7, 7nvz:7, 7nw0:7, 6o9l:7, 6ro4:A, 8wak:6, 8wal:6, 8wan:6, 8wao:6, 8wap:6, 8waq:6, 8war:6, 8was:6
81 7lbm:W 574 202 0.0625 0.0767 0.2178 0.071
82 8ebu:A 604 207 0.0639 0.0745 0.2174 0.072 8ebt:A, 8ebx:A, 8eby:A
83 8y6o:I 597 97 0.0312 0.0369 0.2268 0.19 8qp8:G, 6qw6:5X, 6qx9:5X, 8r08:G
84 6vtv:B 252 139 0.0568 0.1587 0.2878 1.3 6vtv:A
85 6yw5:WW 353 79 0.0284 0.0567 0.2532 4.2 6ywe:WW, 6ywx:WW, 6ywy:WW
86 2v4j:A 436 54 0.0256 0.0413 0.3333 5.8 2v4j:D
87 3rc8:A 610 44 0.0241 0.0279 0.3864 7.0 3rc3:A
88 4rk9:A 384 103 0.0369 0.0677 0.2524 7.5 4rk9:B
89 2yy7:A 312 75 0.0270 0.0609 0.2533 8.3 2yy7:B
90 2wjy:A 773 73 0.0312 0.0285 0.3014 9.7 2gjk:A, 2gk6:A, 2gk6:B, 2gk7:A, 8rxb:E, 8rxb:A, 8rxb:D, 8rxb:I, 8rxb:L, 8rxb:P, 2wjv:A, 2wjv:B, 2xzo:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218