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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
PQSVSRAAITAAYRRPETEAVSMLLEQARLPQPVAEQAHKLAYQLADKLRNQKNASGRAGMGVALMCLAEALLRIPDKAT
RDALIRDSGEPLIRKGVDMAMRLMGEQFVTGETIAEALANARKLEEKGFRYSYDMLGEAALTAADAQAYMVSYQQAIHAI
GKASNGRGIYEGPGISIKLSALHPRYSRAQYDRVMEELYPRLKSLTLLARQYDIGINIDAEESDRLEISLDLLEKLCFEP
ELAGWNGIGFVIQAYQKRCPLVIDYLIDLATRSRRRLMIRLVKGAYWDSEIKRAQMDGLEGYPVYTRKVYTDVSYLACAK
KLLAVPNLIYPQFATHNAHTLAAIYQLAGQNYYPGQYEFQCLHGMGEPLYEQVTGKVADGKLNRPCRIYAPVGTHETLLA
YLVRRLLENGANTSFVNRIADTSLPLDELVADPVTAVEKLAQQEGQTGLPHPKIPLPRD

The query sequence (length=459) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 1tj0:A 469 472 0.9913 0.9701 0.9640 0.0 3e2q:A, 3e2r:A, 3e2s:A, 2fzm:A, 4o8a:A, 1tiw:A, 1tj1:A, 1tj2:A
2 2fzn:A 449 458 0.9782 1.0000 0.9803 0.0
3 7sqn:A 503 503 0.9978 0.9105 0.9105 0.0 3itg:B, 4jny:A, 4jnz:A, 7mwt:A, 7mwu:A, 7mwv:A
4 3itg:A 399 459 0.8475 0.9749 0.8475 0.0
5 6x9d:A 1218 516 0.6863 0.2586 0.6105 0.0 8dkq:A, 5kf6:A, 5kf6:B, 5kf7:A, 7my9:A, 7my9:B, 7mya:A, 7mya:B, 7myb:A, 7myb:B, 7myc:A, 7myc:B, 6ufp:A, 6ufp:B, 6vz9:A, 6vz9:B, 8w0k:A, 6x99:A, 6x99:B, 6x9a:A, 6x9a:B, 6x9b:A, 6x9b:B, 6x9c:A, 6x9c:B, 6x9d:B
6 8dko:B 393 444 0.5926 0.6921 0.6126 0.0 8dko:A, 8dkp:A, 8dkp:B, 8dkq:B, 8w0k:B
7 3haz:A 983 506 0.4880 0.2279 0.4427 7.66e-125 6bsn:A, 6bsn:B, 3haz:B, 4q71:A, 4q71:B, 4q72:A, 4q72:B, 4q73:A, 4q73:B
8 5ur2:B 959 372 0.2593 0.1241 0.3199 1.32e-47 5ur2:A, 5ur2:C, 5ur2:D
9 7na0:A 981 381 0.2571 0.1203 0.3097 6.07e-38 7na0:B, 4nm9:A, 4nm9:B, 4nma:A, 4nma:B, 4nmb:A, 4nmb:B, 4nmc:B, 4nmd:A, 4nmd:B, 4nme:A, 4nme:B, 4nmf:A, 4nmf:B
10 4nmc:A 941 360 0.2375 0.1158 0.3028 1.99e-31
11 2g37:B 300 294 0.1786 0.2733 0.2789 1.98e-13 2ekg:A, 2ekg:B, 2g37:A, 5m42:A
12 4h6q:A 281 322 0.1852 0.3025 0.2640 3.41e-12 4h6q:C, 4h6r:A, 4h6r:C
13 5ux5:A 963 309 0.2004 0.0955 0.2977 4.67e-09 5ux5:B, 5ux5:C, 5ux5:D
14 1wy7:D 204 73 0.0566 0.1275 0.3562 3.1 1wy7:A, 1wy7:B, 1wy7:C
15 8k17:B 362 46 0.0370 0.0470 0.3696 3.8
16 1oao:C 729 55 0.0370 0.0233 0.3091 5.0 3git:A, 3git:B, 3git:C, 3git:D, 3git:E, 3git:F, 3i01:M, 3i01:N, 3i01:O, 3i01:P, 3i04:M, 3i04:N, 3i04:O, 3i04:P, 1mjg:M, 1mjg:N, 1mjg:O, 1mjg:P, 1oao:D, 6x5k:M, 6x5k:N, 6x5k:O, 6x5k:P, 2z8y:M, 2z8y:N, 2z8y:O, 2z8y:P
17 2bzf:A 88 57 0.0414 0.2159 0.3333 8.8
18 5me6:A 175 58 0.0349 0.0914 0.2759 8.9 5me6:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218