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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
PPRKVLIISAGASHSVALLSGDIVCSWGRGEDGQLGHGDAEDRPSPTQLSALDGHQIVSVTCGADHTVAYSQSGMEVYSW
GWGDFGRLGHGNSSDLFTPLPIKALHGIRIKQIACGDSHCLAVTMEGEVQSWGRNQNGQLGLGDTEDSLVPQKIQAFEGI
RIKMVAAGAEHTAAVTEDGDLYGWGWGRYGNLGLGDRTDRLVPERVTSTGGEKMSMVACGWRHTISVSYSGALYTYGWSK
YGQLGHGDLEDHLIPHKLEALSNSFISQISGGFRHTMALTSDGKLYGWGWNKFGQVGVGNNLDQCSPVQVRFPDDQKVVQ
VSCGWRHTLAVTERNNVFAWGRGTNGQLGIGESVDRNFPKIIEALSVDG

The query sequence (length=369) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4nbm:C 369 369 0.9973 0.9973 0.9973 0.0 4nbm:D, 4nc4:A, 4nc4:C
2 4o2w:A 365 327 0.3144 0.3178 0.3547 7.55e-62 4o2w:B, 4o2w:D
3 4o2w:A 365 343 0.3252 0.3288 0.3499 7.28e-60 4o2w:B, 4o2w:D
4 4o2w:A 365 278 0.2764 0.2795 0.3669 6.41e-49 4o2w:B, 4o2w:D
5 4o2w:A 365 295 0.2304 0.2329 0.2881 3.42e-41 4o2w:B, 4o2w:D
6 4o2w:A 365 224 0.2222 0.2247 0.3661 1.05e-40 4o2w:B, 4o2w:D
7 7q41:A 369 348 0.3225 0.3225 0.3420 2.21e-53 7q41:C, 7q41:E, 7q42:C, 7q42:A, 7q42:E, 7q43:A, 7q43:C, 7q43:E, 7q44:C, 7q44:A, 7q44:E, 7q45:A, 7q45:C, 7q45:E, 7q46:C, 7q46:E, 7q46:A
8 7q41:A 369 333 0.3008 0.3008 0.3333 8.31e-53 7q41:C, 7q41:E, 7q42:C, 7q42:A, 7q42:E, 7q43:A, 7q43:C, 7q43:E, 7q44:C, 7q44:A, 7q44:E, 7q45:A, 7q45:C, 7q45:E, 7q46:C, 7q46:E, 7q46:A
9 7q41:A 369 280 0.2710 0.2710 0.3571 3.20e-50 7q41:C, 7q41:E, 7q42:C, 7q42:A, 7q42:E, 7q43:A, 7q43:C, 7q43:E, 7q44:C, 7q44:A, 7q44:E, 7q45:A, 7q45:C, 7q45:E, 7q46:C, 7q46:E, 7q46:A
10 7q41:A 369 295 0.2683 0.2683 0.3356 4.79e-48 7q41:C, 7q41:E, 7q42:C, 7q42:A, 7q42:E, 7q43:A, 7q43:C, 7q43:E, 7q44:C, 7q44:A, 7q44:E, 7q45:A, 7q45:C, 7q45:E, 7q46:C, 7q46:E, 7q46:A
11 7q41:A 369 226 0.2358 0.2358 0.3850 2.93e-41 7q41:C, 7q41:E, 7q42:C, 7q42:A, 7q42:E, 7q43:A, 7q43:C, 7q43:E, 7q44:C, 7q44:A, 7q44:E, 7q45:A, 7q45:C, 7q45:E, 7q46:C, 7q46:E, 7q46:A
12 7q41:A 369 247 0.2331 0.2331 0.3482 6.21e-35 7q41:C, 7q41:E, 7q42:C, 7q42:A, 7q42:E, 7q43:A, 7q43:C, 7q43:E, 7q44:C, 7q44:A, 7q44:E, 7q45:A, 7q45:C, 7q45:E, 7q46:C, 7q46:E, 7q46:A
13 7q41:A 369 69 0.0623 0.0623 0.3333 1.28e-06 7q41:C, 7q41:E, 7q42:C, 7q42:A, 7q42:E, 7q43:A, 7q43:C, 7q43:E, 7q44:C, 7q44:A, 7q44:E, 7q45:A, 7q45:C, 7q45:E, 7q46:C, 7q46:E, 7q46:A
14 3mvd:L 394 376 0.3035 0.2843 0.2979 1.31e-30 3mvd:K
15 3mvd:L 394 270 0.2249 0.2107 0.3074 9.51e-19 3mvd:K
16 4d4o:A 414 183 0.1355 0.1208 0.2732 1.42e-08 4d4o:C, 4d4p:A, 4d4p:C, 4d4p:G, 4d4p:H, 4x33:A, 4x33:B, 1yop:A, 1yws:A
17 4d4o:A 414 291 0.1789 0.1594 0.2268 1.18e-04 4d4o:C, 4d4p:A, 4d4p:C, 4d4p:G, 4d4p:H, 4x33:A, 4x33:B, 1yop:A, 1yws:A
18 4d4o:A 414 190 0.1301 0.1159 0.2526 0.065 4d4o:C, 4d4p:A, 4d4p:C, 4d4p:G, 4d4p:H, 4x33:A, 4x33:B, 1yop:A, 1yws:A
19 4d4o:A 414 336 0.2141 0.1908 0.2351 0.070 4d4o:C, 4d4p:A, 4d4p:C, 4d4p:G, 4d4p:H, 4x33:A, 4x33:B, 1yop:A, 1yws:A
20 1jtd:B 273 250 0.1734 0.2344 0.2560 7.24e-06
21 1jtd:B 273 242 0.1762 0.2381 0.2686 5.02e-04
22 1jtd:B 273 182 0.1436 0.1941 0.2912 0.002
23 6gaw:Ae 388 43 0.0434 0.0412 0.3721 0.40 6gaz:Ae, 7nqh:Ae, 7nql:Ae, 7nsi:Ae, 7nsj:Ae, 8oin:AV, 8oip:AV, 6ydp:Ae, 6ydw:Ae
24 2z8g:A 549 69 0.0596 0.0401 0.3188 0.89 3wwg:B, 3wwg:C, 2z8g:B
25 8bja:A 1563 191 0.1138 0.0269 0.2199 1.2
26 8bja:A 1563 97 0.0732 0.0173 0.2784 7.3
27 8ewi:A 1775 103 0.0650 0.0135 0.2330 3.7 8ewi:B, 8ewi:C, 8ewi:D
28 8d4x:B 1669 103 0.0650 0.0144 0.2330 3.7 8c06:A, 8c06:D
29 8e0q:A 1689 103 0.0650 0.0142 0.2330 3.8 8d4x:A, 8e0q:B
30 3pqd:B 312 88 0.0650 0.0769 0.2727 3.9 3pqd:A, 3pqd:C, 3pqd:D, 3pqd:F, 3pqd:H, 3pqd:E, 3pqd:G, 3pqf:C, 3pqf:D
31 4efp:A 235 57 0.0461 0.0723 0.2982 5.1 4efp:B, 4efq:A, 4efq:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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