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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
PKVRVVVDNDPVPTSFEKWAKPGHFDRTLARGPQTTTWIWNLHALAHDFDTHTSDLEDISRKIFSAHFGHLAVVFIWLSG
MYFHGAKFSNYEAWLADPTGIKPSAQVVWPIVGQGILNGDVGGGFHGIQITSGLFQLWRASGITNEFQLYCTAIGGLVMA
GLMLFAGWFHYHKRAPKLEWFQNVESMLNHHLAGLLGLGSLAWAGHQIHVSLPINKLLDAGVAAKDIPLPHEFILNPSLM
AELYPKVDWGFFSGVIPFFTFNWAAYSDFLTFNGGLNPVTGGLWLSDTAHHHLAIAVLFIIAGHMYRTNWGIGHSLKEIL
EAHKGPFTGAGHKGLYEVLTTSWHAQLAINLAMMGSLSIIVAQHMYAMPPYPYLATDYPTQLSLFTHHMWIGGFLVVGGA
AHGAIFMVRDYDPAMNQNNVLDRVLRHRDAIISHLNWVCIFLGFHSFGLYVHNDTMRAFGRPQDMFSDTGIQLQPVFAQW
VQNLHTLAPGGTAPNAAATASVAFGGDVVAVGGKVAMMPIVLGTADFMVHHIHAFTIHVTVLILLKGVLFARSSRLIPDK
ANLGFRFPCDGPGRGGTCQVSGWDHVFLGLFWMYNCISVVIFHFSWKMQSDVWGTVAPDGTVSHITGGNFAQSAITINGW
LRDFLWAQASQVIGSYGSALSAYGLLFLGAHFIWAFSLMFLFSGRGYWQELIESIVWAHNKLKVAPAIQPRALSIIQGRA
VGVAHYLLGGIATTWAFFLARIISVG

The query sequence (length=746) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6tra:A 746 746 1.0000 1.0000 1.0000 0.0 4fe1:A, 7fix:A1, 7fix:A2, 7fix:A3, 1jb0:A, 6k33:aA, 6k33:bA, 6k33:cA, 6lu1:A, 7m75:A, 7m76:A, 7m78:A, 3pcq:A, 6pfy:A, 6pfy:G, 6pfy:Y, 6pgk:A, 6pgk:G, 6pgk:Y, 6trc:A, 6trc:a, 6trc:1, 6trd:A, 6trd:a, 6trd:1, 5zf0:A1, 5zf0:A2, 5zf0:A3, 5zf0:A4, 5zf0:A6, 5zf0:A5
2 6k61:A 742 745 0.8686 0.8733 0.8698 0.0 6jeo:aA, 6jeo:bA, 6jeo:cA, 6jeo:dA, 6k61:a, 6tcl:A1, 6tcl:A2, 6tcl:A, 6tcl:AA, 7y3f:A
3 5oy0:A 751 745 0.8727 0.8668 0.8738 0.0 8am5:a, 8asl:a, 8asp:a, 6hqb:A, 4kt0:A, 4l6v:A, 4l6v:a, 4l6v:1, 6nwa:A, 6nwa:a, 6nwa:H, 7o1v:A, 5oy0:a, 5oy0:1, 7umh:A, 7umh:H, 7umh:a, 6uzv:A, 6uzv:a, 6uzv:1, 6vpv:A, 6vpv:a, 6vpv:1
4 7y5e:AN 745 745 0.8566 0.8577 0.8577 0.0 7y5e:A2, 7y7a:A7, 7y7a:Ao
5 8wm6:A 742 745 0.8418 0.8464 0.8430 0.0 8wmj:A, 8wmv:A, 8wmw:A, 7y7b:A, 7y8a:A
6 6kif:A 751 756 0.8552 0.8495 0.8439 0.0 6kif:G, 6kif:e, 6kig:A, 6kig:G, 6kig:e
7 7yca:A 742 744 0.8472 0.8518 0.8495 0.0 7a4p:A, 7bgi:A, 7blx:A, 8cmo:A, 7d0j:A, 7dz7:A, 7dz8:A, 8h2u:A, 6ijj:A, 6ijo:A, 6jo5:A, 6jo6:A, 7r3k:A, 7wyi:A, 7wzn:A, 7zq9:A, 7zqc:A, 7zqd:A, 7zqd:A2, 6zzx:A, 6zzy:A
8 7blz:A 743 734 0.8378 0.8412 0.8515 0.0 6fos:A, 8wey:A, 5zgb:A, 5zgh:A
9 7dr0:A 739 743 0.8298 0.8376 0.8331 0.0 7dr1:A, 7dr2:aA, 7dr2:bA, 7dr2:cA, 7dr2:dA
10 5l8r:A 743 747 0.8284 0.8318 0.8273 0.0 8bcv:A, 8bcw:A, 7dkz:A, 7ew6:A, 7ewk:A, 7f9o:A, 7f9o:e, 8htu:A, 8j6z:A, 8j7a:A, 8j7b:A, 7ksq:A, 7kux:A, 6l35:A, 3lw5:A, 2o01:A, 4rku:A, 7wfd:AA, 7wfe:BA, 7wg5:AA, 7wg5:BA, 8wgh:A, 2wsc:A, 2wse:A, 2wsf:A, 4xk8:A, 4xk8:a, 7xqp:A, 4y28:A, 6yac:A, 6yez:A, 5zji:A, 6zoo:A, 6zxs:A
11 7qco:A 728 732 0.8378 0.8585 0.8538 0.0 7qco:E, 7qco:e, 7qco:a
12 6igz:A 740 745 0.8231 0.8297 0.8242 0.0 6qph:A, 6rhz:A, 6sl5:A, 6yxr:A
13 6ly5:a 742 744 0.8083 0.8127 0.8105 0.0 6l4u:A
14 6kmw:aA 721 725 0.8244 0.8530 0.8483 0.0 6kmw:bA, 6kmw:cA
15 7lx0:G 751 753 0.8338 0.8282 0.8260 0.0 7lx0:a, 7lx0:A, 6pnj:A, 6pnj:G, 6pnj:a
16 7s3d:A 749 749 0.8097 0.8064 0.8064 0.0 7s3d:G, 7s3d:a
17 7dwq:A 726 727 0.7453 0.7658 0.7648 0.0
18 7coy:aA 685 717 0.7198 0.7839 0.7490 0.0 7coy:bA, 7coy:cA
19 6kmx:aA 717 721 0.7399 0.7699 0.7656 0.0 6kmx:bA, 6kmx:cA
20 7f4v:aA 772 775 0.7520 0.7267 0.7239 0.0 7f4v:bA, 7f4v:cA
21 8jjr:a 665 728 0.4692 0.5263 0.4808 0.0
22 8jze:a 670 729 0.4517 0.5030 0.4623 0.0 8jzf:a
23 8jw0:a 645 718 0.4759 0.5504 0.4944 0.0
24 7f4v:aB 725 758 0.4745 0.4883 0.4670 0.0 7f4v:bB, 7f4v:cB
25 7blz:B 731 755 0.4584 0.4679 0.4530 0.0 6fos:B, 8wey:B, 5zgb:B, 5zgh:B
26 6ly5:b 732 756 0.4504 0.4590 0.4444 0.0 6l4u:B
27 6kmw:aB 740 769 0.4638 0.4676 0.4499 0.0 6kmw:cB, 6kmw:bB
28 7y5e:BN 732 757 0.4544 0.4631 0.4478 0.0 7y5e:B2, 7y7a:B7, 7y7a:Bo, 7y7b:B, 7y8a:B
29 6kif:B 733 759 0.4651 0.4734 0.4572 0.0 6kif:H, 6kif:f, 6kig:B, 6kig:H, 6kig:f
30 6vpv:B 737 761 0.4558 0.4613 0.4468 0.0 8am5:b, 8asl:b, 8asp:b, 6hqb:B, 4kt0:B, 4l6v:B, 4l6v:b, 4l6v:2, 6nwa:B, 6nwa:b, 6nwa:G, 7o1v:B, 5oy0:B, 5oy0:b, 5oy0:2, 7umh:B, 7umh:G, 7umh:b, 6uzv:B, 6uzv:b, 6uzv:2, 6vpv:b, 6vpv:2
31 8wm6:B 732 757 0.4544 0.4631 0.4478 0.0 8wmj:B, 8wmv:B, 8wmw:B
32 6igz:B 733 757 0.4544 0.4625 0.4478 0.0
33 7fix:B1 740 765 0.4558 0.4595 0.4444 0.0 7bw2:B, 4fe1:B, 7fix:B2, 7fix:B3, 1jb0:B, 6k33:aB, 6k33:bB, 6k33:cB, 7m75:B, 7m76:B, 7m78:B, 3pcq:B, 6pfy:H, 6pfy:B, 6pfy:Z, 6pgk:H, 6pgk:B, 6pgk:Z, 6tra:B, 6trc:B, 6trc:b, 6trc:2, 6trd:B, 6trd:b, 6trd:2, 5zf0:B1, 5zf0:B2, 5zf0:B3, 5zf0:B4, 5zf0:B6, 5zf0:B5
34 7d0j:B 734 757 0.4491 0.4564 0.4425 0.0 7a4p:B, 7bgi:B, 7blx:B, 8cmo:B, 7dz7:B, 7dz8:B, 8h2u:B, 6ijj:B, 6ijo:B, 6jo5:B, 6jo6:B, 6qph:B, 7r3k:B, 6rhz:B, 6sl5:B, 7wyi:B, 7wzn:B, 6yxr:B, 7zq9:B, 7zqc:B, 7zqd:B, 7zqd:B2, 6zzx:B, 6zzy:B
35 7yca:B 732 756 0.4517 0.4604 0.4458 0.0
36 7s3d:B 742 766 0.4477 0.4501 0.4360 0.0 7s3d:H, 7s3d:b
37 6kmx:aB 727 761 0.4397 0.4512 0.4310 0.0 6kmx:bB, 6kmx:cB
38 7qco:B 734 761 0.4397 0.4469 0.4310 0.0 7qco:G, 7qco:g, 7qco:b
39 7wfd:AB 734 741 0.4370 0.4441 0.4399 0.0 8bcv:B, 8bcw:B, 7dkz:B, 7ew6:B, 7ewk:B, 7f9o:B, 7f9o:f, 8htu:B, 8j6z:B, 8j7a:B, 8j7b:B, 7ksq:B, 7kux:B, 6l35:B, 5l8r:B, 3lw5:B, 2o01:B, 4rku:B, 7wfe:BB, 7wg5:AB, 7wg5:BB, 8wgh:B, 2wsc:B, 2wse:B, 2wsf:B, 4xk8:B, 4xk8:b, 7xqp:B, 4y28:B, 6yac:B, 6yez:B, 5zji:B, 6zoo:B, 6zxs:B
40 7lx0:H 739 768 0.4397 0.4438 0.4271 0.0 7lx0:b, 7lx0:B, 6pnj:H, 6pnj:B, 6pnj:b
41 6lu1:B 713 758 0.4397 0.4600 0.4327 0.0
42 6k61:B 740 765 0.4410 0.4446 0.4301 0.0 6jeo:aB, 6jeo:bB, 6jeo:cB, 6jeo:dB, 6k61:b, 6tcl:B1, 6tcl:B2, 6tcl:B, 6tcl:BB, 7y3f:B
43 7dr0:B 706 761 0.4316 0.4561 0.4231 0.0 7dr1:B, 7dr2:aB, 7dr2:bB, 7dr2:cB, 7dr2:dB
44 7dwq:B 659 756 0.4048 0.4583 0.3995 6.24e-174 7coy:aB, 7coy:bB, 7coy:cB
45 8jw0:b 617 711 0.3003 0.3630 0.3150 6.17e-99
46 8jjr:b 659 743 0.3204 0.3627 0.3217 9.61e-98
47 8jze:b 663 715 0.3110 0.3499 0.3245 2.10e-97 8jzf:b
48 5v8k:A 600 225 0.0858 0.1067 0.2844 4.20e-15
49 7zq9:B2 180 192 0.0764 0.3167 0.2969 1.11e-13
50 6m32:A 628 174 0.0630 0.0748 0.2701 0.001 6m32:a
51 8gwa:A 667 174 0.0630 0.0705 0.2701 0.002 8gwa:a, 7uea:A, 7uea:a, 7ueb:A, 7ueb:a, 7z6q:A, 7z6q:a
52 8abs:A 394 63 0.0282 0.0533 0.3333 0.18 8abr:A, 5ofq:A, 5ofq:B, 5ofq:C, 5ofq:D
53 7vzg:a 858 120 0.0416 0.0361 0.2583 0.19 7vzg:A, 7vzr:A, 7vzr:a
54 7xg0:D 331 95 0.0349 0.0785 0.2737 1.0 7xfz:C, 7xg0:C, 7xg0:E, 7xg0:F, 7xg1:C, 7xg1:D, 7xg1:E, 7xg2:C, 7xg2:D, 7xg2:E, 7xg2:F, 7xg3:C, 7xg3:D, 7xg3:E, 7xg3:F, 7xg4:C, 7xg4:D, 7xg4:E, 7xg4:F
55 6ped:B 126 42 0.0201 0.1190 0.3571 7.3
56 4b3g:A 614 98 0.0349 0.0423 0.2653 8.2 4b3g:B
57 6jv0:A 273 78 0.0255 0.0696 0.2436 8.7 6juz:A, 6jv1:A
58 3bvi:F 173 76 0.0308 0.1329 0.3026 8.8 3bvf:A, 3bvf:B, 3bvf:C, 3bvf:D, 3bvf:E, 3bvf:F, 3bvi:A, 3bvi:B, 3bvi:C, 3bvi:D, 3bvi:E, 3bvk:A, 3bvk:B, 3bvk:C, 3bvk:D, 3bvk:E, 3bvk:F, 3bvl:A, 3bvl:B, 3bvl:C, 3bvl:D, 3bvl:E, 3bvl:F, 5c6f:A, 5c6f:B, 5c6f:J, 5c6f:K, 3egm:A, 3egm:B, 3egm:C, 3egm:D, 3egm:E, 3egm:F

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218