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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
NVCSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRGSYKEFAVHLKRGPGQAEAPAGVESILLTIKDDTIYLTRHLAVLNG
AVVSTPHYSPGLLIEKSDAYTKVYSRAGLTLMWNREDALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSPLEFG
NMQKINQPDVVCEDPEEEVAPASCSEHRAECERLLTAEAFADCQDLVPLEPYLRACQQDRCRCPGGDTCVCSTVAEFSRQ
CSHAGGRPGNWRTATLCPKTCPGNLVYLESGSPCMDTCSHLEVSSLCEEHRMDGCFCPEGTVYDDIGDSGCVPVSQCHCR
LHGHLYTPGQEITNDCEQCVCNAGRWVCKDLPCPGTCALEGGSHITTFDGKTYTFHGDCYYVLAKGDHNDSYALLGELAP
CGSTDKQTCLKTVVLLADKKKNAVVFKSDGSVLLNQLQVNLPHVTASFSVFRPSSYHIMVSMAIGVRLQVQLAPVMQLFV
TLDQASQGQVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTWKAQSTCHDKLDWLDDPCSLNIESANYAEHWCSLLKKT
ETPFGRCHSAVDPAEYYKRCKYDTCNCQNNEDCLCAALSSYARACTAKGVMLWGWREHVCNKDVGSCPNSQVFLYNLTTC
QQTCRSLSEADSHCLEGFAPVDGCGCPDHTFLDEKGRCVPLAKCSCYGLYLEAGDVVRCVCRDGRLHCRALSCQTLAAGY
YHVCPDGLMDDGRGGCVVEKECPCVHNNDLYSSGAKIKVDCNTCTCKRGRWVCTQAVCHGTCSIYGSGHYITFDGKYYDF
DGHCSYVAVQDYCGLGSFSIITENVPCGTTGVTCSKAIKIFMGRTELKLEDKHRVVIQRDEGHHVAYTTREVGQYLVVES
STGIIVIWDKRTTVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWKEAPTCPDVSTNPEPCSLNPH
RRSWAEKQCSILKSSVFSICHSKVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQECTKEGACVFWRTPDLCPIFCD
YYNPPHECEWHYEPCGNRSFETCRTINGIHSNISVSYLEGCYPRCPKDRPIYEEDLKKCVTADKCGCYVEDTHYP

The query sequence (length=1115) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7a5o:A 1205 1115 1.0000 0.9253 1.0000 0.0 7a5o:B, 7a5o:C, 7a5o:D, 7a5o:E, 7a5o:F, 7a5o:G, 7a5o:H, 7a5o:I, 7a5o:J, 8ck2:A, 7pov:A, 7pov:B, 7pov:C, 7pov:D, 7pp6:A, 7pp6:B, 7pp6:C, 7pp6:D, 7pp6:E, 7pp6:G, 7prl:A, 6rbf:A, 6rbf:B, 6rbf:C, 6rbf:D, 6tm2:A, 6tm2:B, 6tm2:C, 6tm2:D, 6tm2:E, 6tm2:F, 6tm6:A
2 8oes:A 1168 1155 0.5184 0.4949 0.5004 0.0 8oer:A, 8oer:B, 8oer:C, 8oer:D, 8oes:B, 8oes:C, 8oes:D, 8oes:E, 8oes:F, 8oes:G, 8oes:H
3 8d3d:A 1314 1130 0.3480 0.2953 0.3434 0.0 8d3c:A, 8d3c:B, 8d3c:C, 8d3c:D, 8d3c:E, 8d3c:F, 8d3c:G, 8d3c:H, 8d3c:I, 8d3c:J, 8d3c:K, 8d3c:L, 8d3c:M, 8d3c:N, 8d3c:O, 8d3c:P, 8d3d:B, 8d3d:C, 8d3d:D, 8d3d:E, 8d3d:F, 8d3d:G, 8d3d:H, 8d3d:I, 8d3d:J, 8d3d:K, 8d3d:L, 8d3d:M, 8d3d:N, 8d3d:O, 8d3d:P, 7f49:A, 3hxo:A, 3hxq:A, 7wn3:A, 7wn3:B, 7wn3:E, 7wn3:G, 7wn4:E, 7wn4:G, 7wn6:A, 7wn6:B, 7wn6:E, 7wn6:G, 7wpp:E, 7wpp:G, 7wpq:A, 7wpq:B, 7wpq:E, 7wpq:G, 7wpr:A, 7wpr:B, 7wpr:E, 7wpr:F, 7wpr:G, 7wpr:H, 7wpr:I, 7wpr:J, 7wpr:K, 7wpr:L, 7wpr:M, 7wpr:N, 7wpr:O, 7wpr:P, 7wpr:Q, 7wpr:R, 7wps:A, 7wps:B, 7wps:E, 7wps:G, 7wps:I, 7wps:K, 7wps:M, 7wps:O, 7wps:Q, 7wps:S, 7wps:U, 7wps:W, 7wps:Y, 7wps:a, 7wqt:A, 7wqt:B, 7wqt:E, 7wqt:F, 7wqt:G, 7wqt:H, 7wqt:I, 7wqt:J, 7wqt:K, 7wqt:L, 7wqt:M, 7wqt:N, 7wqt:O, 7wqt:P, 7wqt:Q, 7wqt:R
4 8d3d:A 1314 771 0.2027 0.1720 0.2931 3.44e-78 8d3c:A, 8d3c:B, 8d3c:C, 8d3c:D, 8d3c:E, 8d3c:F, 8d3c:G, 8d3c:H, 8d3c:I, 8d3c:J, 8d3c:K, 8d3c:L, 8d3c:M, 8d3c:N, 8d3c:O, 8d3c:P, 8d3d:B, 8d3d:C, 8d3d:D, 8d3d:E, 8d3d:F, 8d3d:G, 8d3d:H, 8d3d:I, 8d3d:J, 8d3d:K, 8d3d:L, 8d3d:M, 8d3d:N, 8d3d:O, 8d3d:P, 7f49:A, 3hxo:A, 3hxq:A, 7wn3:A, 7wn3:B, 7wn3:E, 7wn3:G, 7wn4:E, 7wn4:G, 7wn6:A, 7wn6:B, 7wn6:E, 7wn6:G, 7wpp:E, 7wpp:G, 7wpq:A, 7wpq:B, 7wpq:E, 7wpq:G, 7wpr:A, 7wpr:B, 7wpr:E, 7wpr:F, 7wpr:G, 7wpr:H, 7wpr:I, 7wpr:J, 7wpr:K, 7wpr:L, 7wpr:M, 7wpr:N, 7wpr:O, 7wpr:P, 7wpr:Q, 7wpr:R, 7wps:A, 7wps:B, 7wps:E, 7wps:G, 7wps:I, 7wps:K, 7wps:M, 7wps:O, 7wps:Q, 7wps:S, 7wps:U, 7wps:W, 7wps:Y, 7wps:a, 7wqt:A, 7wqt:B, 7wqt:E, 7wqt:F, 7wqt:G, 7wqt:H, 7wqt:I, 7wqt:J, 7wqt:K, 7wqt:L, 7wqt:M, 7wqt:N, 7wqt:O, 7wqt:P, 7wqt:Q, 7wqt:R
5 8d3d:A 1314 346 0.0933 0.0791 0.3006 1.99e-26 8d3c:A, 8d3c:B, 8d3c:C, 8d3c:D, 8d3c:E, 8d3c:F, 8d3c:G, 8d3c:H, 8d3c:I, 8d3c:J, 8d3c:K, 8d3c:L, 8d3c:M, 8d3c:N, 8d3c:O, 8d3c:P, 8d3d:B, 8d3d:C, 8d3d:D, 8d3d:E, 8d3d:F, 8d3d:G, 8d3d:H, 8d3d:I, 8d3d:J, 8d3d:K, 8d3d:L, 8d3d:M, 8d3d:N, 8d3d:O, 8d3d:P, 7f49:A, 3hxo:A, 3hxq:A, 7wn3:A, 7wn3:B, 7wn3:E, 7wn3:G, 7wn4:E, 7wn4:G, 7wn6:A, 7wn6:B, 7wn6:E, 7wn6:G, 7wpp:E, 7wpp:G, 7wpq:A, 7wpq:B, 7wpq:E, 7wpq:G, 7wpr:A, 7wpr:B, 7wpr:E, 7wpr:F, 7wpr:G, 7wpr:H, 7wpr:I, 7wpr:J, 7wpr:K, 7wpr:L, 7wpr:M, 7wpr:N, 7wpr:O, 7wpr:P, 7wpr:Q, 7wpr:R, 7wps:A, 7wps:B, 7wps:E, 7wps:G, 7wps:I, 7wps:K, 7wps:M, 7wps:O, 7wps:Q, 7wps:S, 7wps:U, 7wps:W, 7wps:Y, 7wps:a, 7wqt:A, 7wqt:B, 7wqt:E, 7wqt:F, 7wqt:G, 7wqt:H, 7wqt:I, 7wqt:J, 7wqt:K, 7wqt:L, 7wqt:M, 7wqt:N, 7wqt:O, 7wqt:P, 7wqt:Q, 7wqt:R
6 7pmv:B 1141 1154 0.3525 0.3444 0.3406 0.0 7kwo:V, 6n29:A, 6n29:B, 7pmv:A, 7pmv:D, 7pmv:E, 7pnf:B, 7pnf:D, 7wn3:F, 7wn3:H, 7wn3:C, 7wn3:D, 7wn4:F, 7wn4:H, 7wn6:F, 7wn6:H, 7wn6:C, 7wn6:D, 7wpp:F, 7wpp:H, 7wpq:C, 7wpq:D, 7wpq:F, 7wpq:H, 7wpr:a, 7wpr:b, 7wpr:C, 7wpr:c, 7wpr:D, 7wpr:d, 7wpr:e, 7wpr:f, 7wpr:S, 7wpr:T, 7wpr:U, 7wpr:V, 7wpr:W, 7wpr:X, 7wpr:Y, 7wpr:Z, 7wps:Z, 7wps:b, 7wps:C, 7wps:D, 7wps:F, 7wps:H, 7wps:J, 7wps:L, 7wps:N, 7wps:P, 7wps:R, 7wps:T, 7wps:V, 7wps:X, 7wqt:a, 7wqt:b, 7wqt:C, 7wqt:c, 7wqt:D, 7wqt:d, 7wqt:e, 7wqt:f, 7wqt:S, 7wqt:T, 7wqt:U, 7wqt:V, 7wqt:W, 7wqt:X, 7wqt:Y, 7wqt:Z, 7zwh:D, 7zwh:E
7 7pmv:B 1141 771 0.2009 0.1963 0.2905 5.35e-78 7kwo:V, 6n29:A, 6n29:B, 7pmv:A, 7pmv:D, 7pmv:E, 7pnf:B, 7pnf:D, 7wn3:F, 7wn3:H, 7wn3:C, 7wn3:D, 7wn4:F, 7wn4:H, 7wn6:F, 7wn6:H, 7wn6:C, 7wn6:D, 7wpp:F, 7wpp:H, 7wpq:C, 7wpq:D, 7wpq:F, 7wpq:H, 7wpr:a, 7wpr:b, 7wpr:C, 7wpr:c, 7wpr:D, 7wpr:d, 7wpr:e, 7wpr:f, 7wpr:S, 7wpr:T, 7wpr:U, 7wpr:V, 7wpr:W, 7wpr:X, 7wpr:Y, 7wpr:Z, 7wps:Z, 7wps:b, 7wps:C, 7wps:D, 7wps:F, 7wps:H, 7wps:J, 7wps:L, 7wps:N, 7wps:P, 7wps:R, 7wps:T, 7wps:V, 7wps:X, 7wqt:a, 7wqt:b, 7wqt:C, 7wqt:c, 7wqt:D, 7wqt:d, 7wqt:e, 7wqt:f, 7wqt:S, 7wqt:T, 7wqt:U, 7wqt:V, 7wqt:W, 7wqt:X, 7wqt:Y, 7wqt:Z, 7zwh:D, 7zwh:E
8 7pmv:B 1141 343 0.0924 0.0903 0.3003 1.02e-26 7kwo:V, 6n29:A, 6n29:B, 7pmv:A, 7pmv:D, 7pmv:E, 7pnf:B, 7pnf:D, 7wn3:F, 7wn3:H, 7wn3:C, 7wn3:D, 7wn4:F, 7wn4:H, 7wn6:F, 7wn6:H, 7wn6:C, 7wn6:D, 7wpp:F, 7wpp:H, 7wpq:C, 7wpq:D, 7wpq:F, 7wpq:H, 7wpr:a, 7wpr:b, 7wpr:C, 7wpr:c, 7wpr:D, 7wpr:d, 7wpr:e, 7wpr:f, 7wpr:S, 7wpr:T, 7wpr:U, 7wpr:V, 7wpr:W, 7wpr:X, 7wpr:Y, 7wpr:Z, 7wps:Z, 7wps:b, 7wps:C, 7wps:D, 7wps:F, 7wps:H, 7wps:J, 7wps:L, 7wps:N, 7wps:P, 7wps:R, 7wps:T, 7wps:V, 7wps:X, 7wqt:a, 7wqt:b, 7wqt:C, 7wqt:c, 7wqt:D, 7wqt:d, 7wqt:e, 7wqt:f, 7wqt:S, 7wqt:T, 7wqt:U, 7wqt:V, 7wqt:W, 7wqt:X, 7wqt:Y, 7wqt:Z, 7zwh:D, 7zwh:E
9 8qci:B 269 265 0.0700 0.2900 0.2943 9.94e-22
10 8qci:B 269 272 0.0709 0.2937 0.2904 6.15e-17
11 8qci:B 269 270 0.0592 0.2454 0.2444 5.62e-10
12 7qcl:A 546 350 0.0807 0.1648 0.2571 1.37e-21 7qcl:B, 7qcn:A, 7qcn:B, 7qcu:A, 7qcu:B
13 7qcl:A 546 359 0.0771 0.1575 0.2396 1.69e-17 7qcl:B, 7qcn:A, 7qcn:B, 7qcu:A, 7qcu:B
14 7qcl:A 546 383 0.0879 0.1795 0.2559 1.38e-14 7qcl:B, 7qcn:A, 7qcn:B, 7qcu:A, 7qcu:B
15 7rt0:A 385 72 0.0197 0.0571 0.3056 0.14
16 2e1q:A 1307 106 0.0260 0.0222 0.2736 0.67 6a7x:A, 6a7x:B, 6abu:A, 6abu:B, 6ac1:A, 6ac1:B, 6ac4:A, 6ac4:B, 6ad4:A, 6ad4:B, 6adj:A, 6adj:B, 6aju:A, 6aju:F, 3an1:A, 3an1:B, 3b9j:A, 3b9j:I, 2ckj:B, 2ckj:C, 2ckj:D, 2e1q:B, 2e1q:C, 2e1q:D, 2e3t:A, 2e3t:B, 3etr:A, 3etr:L, 3eub:A, 3eub:J, 3eub:S, 3eub:2, 1fiq:A, 3nrz:A, 3nrz:J, 3ns1:A, 3ns1:J, 3nvv:A, 3nvv:J, 3nvw:A, 3nvw:J, 3nvy:A, 3nvy:J, 3nvz:A, 3nvz:J, 3sr6:A, 3sr6:J, 1wyg:A, 4yrw:A, 4yrw:B, 4ysw:A, 4ysw:B, 4yty:A, 4yty:B, 4ytz:A, 4ytz:B
17 5zmp:A 305 21 0.0108 0.0393 0.5714 2.4
18 8sok:D 630 139 0.0368 0.0651 0.2950 7.8 5h65:A, 3kjo:A, 3kjp:A, 7s1o:A, 7s1o:B, 7s1t:A, 7s1t:D, 7s1t:G, 7s1t:J, 7s1u:A, 7s1u:B, 8sh0:A, 8sh1:A, 8soj:D, 5un7:A, 1xjv:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218