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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
NQPYRTGFHFQPPKNWMNDPNGPMIYKGIYHLFYQWNPKGAVWGNIVWAHSTSTDLINWDPHPPAIFPSAPFDINGCWSG
SATILPNGKPVILYTGIDPKNQQVQNIAEPKNLSDPYLREWKKSPLNPLMAPDAVNGINASSFRDPTTAWLGQDKKWRVI
IGSKIHRRGLAITYTSKDFLKWEKSPEPLHYDDGSGMWECPDFFPVTRFGSNGVETSSFGEPNEILKHVLKISLADTKHD
YYTIGTYDRVKDKFVPDNGFKMDGTAPRYDYGKYYASKTFFDSAKNRRILWGWTNESSSVEDDVEKGWSGIQTIPRKIWL
DRSGKQLIQWPVREVERLRTKQVKNLRNKVLKSGSRLEVYGVTAAQADVEVLFKVRDLEKADVIEPSWTDPQLICSKMNV
SVKSGLGPFGLMVLASKNLEEYTSVYFRIFKARQNSNKYVVLMCSDQSRSSLKEDNDKTTYGAFVDINPHQPLSLRALID
HSVVESFGGKGRACITSRVYPKLAIGKSSHLFAFNYGYQSVDVLNLNAWSMNSAQ

The query sequence (length=535) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 2ac1:A 537 535 0.9981 0.9944 0.9981 0.0 2oxb:A, 2qqu:A, 2qqv:A, 2qqw:A, 2xqr:A, 2xqr:C, 2xqr:G, 2xqr:K, 2xqr:E, 2xqr:I
2 2add:A 537 538 0.5252 0.5233 0.5223 0.0 2ade:A, 2aey:A, 2aez:A
3 3ugg:A 524 532 0.4243 0.4332 0.4267 2.44e-142 3ugg:B, 3ugh:B
4 7vcp:A 490 552 0.2804 0.3061 0.2717 1.73e-37
5 7bwc:A 464 405 0.2299 0.2651 0.3037 4.40e-37
6 6nun:A 516 516 0.2710 0.2810 0.2810 2.61e-36
7 1w2t:A 432 344 0.1907 0.2361 0.2965 3.21e-36 1w2t:B, 1w2t:C, 1w2t:D, 1w2t:E, 1w2t:F
8 1y9g:A 517 534 0.2579 0.2669 0.2584 8.36e-35
9 3pij:B 526 392 0.2093 0.2129 0.2857 3.25e-33 3pij:A
10 3rwk:X 493 554 0.2654 0.2880 0.2563 2.96e-24 3sc7:X
11 6nu8:A 488 410 0.2037 0.2234 0.2659 7.15e-20
12 6s1t:A 512 435 0.2243 0.2344 0.2759 1.79e-19 3kf3:A, 3kf3:B, 6s1t:B, 6s2b:A, 6s2b:B, 3u14:A, 3u14:B, 3u75:A, 3u75:B, 3u75:C, 3u75:D
13 8beq:A 534 216 0.1271 0.1273 0.3148 5.82e-18 8beq:B, 8bes:A, 8bes:B, 8bes:C, 8bes:D, 8bet:A, 8bet:B, 8bet:C, 8bet:D, 8beu:A, 8beu:B, 8beu:C, 8beu:D
14 4ffg:A 480 339 0.1589 0.1771 0.2507 2.05e-10 4ffg:B, 4ffg:C, 4ffg:D, 4ffh:A, 4ffh:B, 4ffh:C, 4ffh:D, 4ffi:A, 4ffi:B, 4ffi:C, 4ffi:D
15 5fix:A 624 586 0.2523 0.2163 0.2304 5.86e-10 5fix:B, 6fje:B, 6fje:A, 6fjg:A, 6fjg:B, 5fk7:A, 5fk7:B, 5fk8:A, 5fk8:B, 5fkb:A, 5fkb:B, 5fkc:A, 5fkc:B, 5fmb:A, 5fmb:B, 5fmc:A, 5fmc:B, 5fmd:A, 5fmd:B, 5nsl:A, 5nsl:B, 5o47:B, 5o47:A, 6s2g:A, 6s2g:B, 6s2h:A, 6s2h:B, 6s3z:A, 6s3z:B, 6s82:A, 6s82:B
16 8aa2:E 497 235 0.1065 0.1147 0.2426 3.54e-04 8aa2:M, 6r3r:A, 6r3u:A, 7znr:A, 7znr:B, 7zns:A, 7zns:B
17 6skz:A 2638 153 0.0785 0.0159 0.2745 0.003 6sl0:A, 6sl0:B
18 6sl1:A 2652 153 0.0785 0.0158 0.2745 0.075 6sky:A, 6sky:B
19 4ied:C 247 86 0.0467 0.1012 0.2907 1.3 4ied:B
20 8tao:B 771 135 0.0654 0.0454 0.2593 3.0 7fd8:A, 7fd8:B, 7fd9:A, 7fd9:B, 3lmk:A, 3lmk:B, 8t8m:A
21 6pwy:B 513 63 0.0318 0.0331 0.2698 3.5 6pwy:A, 6pwy:D, 6pwy:C
22 6ie0:B 347 130 0.0636 0.0980 0.2615 4.2 6ie0:C, 6ie0:D
23 6dzi:7 85 32 0.0206 0.1294 0.3438 5.7 6dzk:T, 8fr8:t, 5o5j:T, 5o61:BT, 8v9j:t, 8v9k:t, 8v9l:t, 8whx:u, 8wi7:u, 8wi9:u, 8wib:u, 8wid:u, 8wif:u, 5xyu:T, 5zeb:t, 5zep:t, 5zeu:t

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218