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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
NKKADENKVKGEAFLTENKNKPGVVVLPSGLQYKVINSGNGVKPGKSDTVTVEYTGRLIDGTVFDSTEKTGKPATFQVSQ
VIPGWTEALQLMPAGSTWEIYVPSGLAYGPRSVGGPIGPNETLIFKIHLISVKK

The query sequence (length=134) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8bjd:A 208 134 1.0000 0.6442 1.0000 1.17e-95 8bje:A, 8bk5:A, 2vcd:A
2 8bk4:A 163 124 0.4478 0.3681 0.4839 1.42e-35 8p3d:A, 8p42:A, 8p42:D
3 1q6i:A 210 132 0.4104 0.2619 0.4167 6.97e-27 1q6i:B
4 8p3c:B 126 111 0.3358 0.3571 0.4054 1.49e-21
5 4giv:A 192 111 0.3284 0.2292 0.3964 4.38e-20 4dz2:A, 4dz2:B, 4dz3:A, 4dz3:B, 4fn2:A, 4fn2:B, 4g50:A, 4g50:B, 4ggq:C, 4ggq:A, 4ggq:B, 4ggq:D, 4giv:B, 5klx:A, 5klx:B, 5klx:D, 5klx:C, 2ko7:A, 2l2s:A, 6o49:A, 6o49:B, 6o4a:A, 6o4a:B, 6o4a:C, 6o4a:D, 3uf8:A, 3uqa:A, 3uqb:A, 5v8t:A, 5v8t:B, 3vaw:A
6 5hw8:B 122 117 0.3507 0.3852 0.4017 1.06e-18 5hw8:A, 5hw8:C, 5hw8:D, 5hw8:E, 5hw8:F, 5hw8:G, 5hw8:H, 6tz6:C, 6tz6:F
7 6tz8:C 111 106 0.3060 0.3694 0.3868 4.20e-16 6tz8:F
8 5hua:A 113 106 0.2985 0.3540 0.3774 1.16e-15 1yat:A
9 7u0s:A 124 107 0.3060 0.3306 0.3832 1.96e-15 5hwc:A, 6tz7:C, 7u0s:B, 7u0u:B, 6vcv:A, 6vcv:B
10 4nnr:A 102 95 0.2537 0.3333 0.3579 3.17e-14 4nnr:B
11 6vrx:A 108 106 0.2910 0.3611 0.3679 1.14e-13 6vct:A, 6vrx:B, 6vrx:C, 6vrx:D
12 8xi9:A 201 107 0.2761 0.1841 0.3458 3.16e-13 1a7x:A, 1a7x:B, 1bkf:A, 1bl4:A, 1bl4:B, 8chi:A, 8chi:B, 8chj:A, 8chj:B, 8chj:C, 8chj:D, 8chk:A, 8chk:B, 8chk:C, 8chl:A, 8chl:B, 8chm:A, 1d7i:A, 1d7i:B, 1d7j:A, 1d7j:B, 2dg3:A, 2dg4:A, 2dg9:A, 4dh0:A, 8er6:A, 8er6:C, 8er6:E, 8er7:A, 8er7:C, 8er7:E, 8era:B, 1f40:A, 1fap:A, 2fap:A, 3fap:A, 4fap:A, 1fkb:A, 1fkd:A, 1fkf:A, 1fkg:A, 1fkh:A, 1fki:A, 1fki:B, 1fkj:A, 1fkl:A, 2fke:A, 1j4h:A, 1j4i:A, 1j4r:A, 1j4r:B, 1j4r:D, 6m4u:A, 6m4u:E, 6m4v:B, 6m4v:D, 6m4w:D, 6m4w:E, 6m4w:F, 1nsg:A, 6oqa:A, 6oqa:B, 6oqa:E, 6oqa:F, 8pdf:A, 8ppz:A, 1qpf:A, 1qpf:D, 1qpl:A, 1qpl:C, 1tco:C, 7u0t:B, 7u8d:A, 7u8d:B, 6vcu:A, 6vcu:C, 6vcu:D, 6vcu:B, 6yf0:A, 6yf1:A, 6yf2:A, 6yf3:A
13 5b8i:C 119 111 0.3060 0.3445 0.3694 3.44e-13
14 1c9h:A 107 107 0.2761 0.3458 0.3458 3.87e-13 5hkg:A
15 6mke:A 117 106 0.2910 0.3333 0.3679 5.55e-13 6mke:B, 6mke:C, 6mke:D
16 5d75:A 120 99 0.2761 0.3083 0.3737 4.41e-12 5gpg:A, 3kz7:A, 1pbk:A
17 3pa7:A 124 94 0.2537 0.2742 0.3617 2.97e-11 3ihz:A, 3ihz:B, 4itz:A, 4itz:B, 4j4o:A, 4mgv:A
18 7f2j:A 117 116 0.2985 0.3419 0.3448 1.31e-10 7f2j:B, 6j2m:A
19 4lax:A 237 106 0.3060 0.1730 0.3868 7.18e-10 4drj:A, 4lay:A, 6rcy:A, 4tw8:A, 4tw8:B
20 4qt3:A 125 94 0.2388 0.2560 0.3404 7.65e-10 4j4n:A, 4j4n:B, 4j4n:C, 4qt2:A, 2vn1:A, 2vn1:B
21 8z38:B 113 98 0.2612 0.3097 0.3571 2.91e-09 8z38:A
22 4msp:A 189 91 0.2388 0.1693 0.3516 6.91e-09 4msp:B
23 5njx:A 413 98 0.2463 0.0799 0.3367 2.49e-07 7a6w:AAA, 7a6w:BBB, 7a6x:AAA, 7aot:A, 7aou:A, 7apq:A, 7aps:A, 7aps:B, 7apt:A, 7apw:A, 7awf:A, 7awx:A, 7awx:B, 7b9y:A, 7b9z:A, 7ba0:A, 8ba6:A, 8baj:A, 5bxj:A, 8cca:A, 8ccb:A, 8ccc:A, 8ccd:A, 8cce:A, 8ccf:A, 8ccg:A, 8cch:A, 8chn:A, 8chp:A, 8chq:A, 8chr:A, 5dit:A, 5diu:A, 5div:A, 4drh:A, 4drh:D, 4dri:A, 4drk:A, 4drk:B, 4drm:A, 4drn:A, 4dro:A, 4drp:A, 4drq:A, 7ett:A, 7etu:A, 7etv:A, 9eu6:A, 9eu7:A, 9eu7:B, 9eu8:A, 9eu8:B, 9eu9:A, 9eu9:B, 9eua:A, 9eua:B, 9eub:A, 9eub:B, 9euc:A, 9euc:B, 9eud:A, 9eud:B, 9eue:A, 9eue:B, 9ey3:A, 9ey4:A, 4jfi:A, 4jfj:A, 4jfk:A, 4jfl:A, 4jfm:A, 3o5f:A, 3o5r:A, 5obk:A, 8pc2:G, 8pc2:H, 8pj8:A, 8pja:A, 7r0l:A, 8r5k:A, 6saf:A, 4tw6:A, 4tw7:A, 4tx0:A, 6tx4:A, 6tx5:A, 6tx6:A, 6tx7:A, 6tx9:A, 6txx:A, 4w9o:A, 4w9o:E, 4w9p:A, 4w9p:E, 4w9q:A
24 4odq:A 106 93 0.2164 0.2736 0.3118 3.13e-06 4odp:A, 4odr:A, 4odr:B, 7oxg:A, 7oxg:B
25 7oxj:A 156 74 0.1791 0.1538 0.3243 7.89e-04 3luo:A, 4odk:A, 4odl:B, 4odl:A, 4odm:A, 4odm:B, 4odm:C, 4odm:D, 4odn:A, 4odo:A, 4odo:C, 4odo:B, 7oxh:A, 7oxi:A, 7oxk:A
26 7ae4:a 67 25 0.0746 0.1493 0.4000 0.34 7ae4:b, 7ae4:c, 7ae4:d, 7ae4:e, 7ae4:f, 7ae5:b, 7ae5:c, 7ae5:d, 7ae5:e, 7ae5:f, 7ae5:a, 7ae7:a, 7ae7:c, 7ae7:d, 7ae7:e, 7ae7:f
27 7ev9:A 382 92 0.1791 0.0628 0.2609 0.41 7ev9:E, 7ev9:I, 8oyi:A, 8oyi:E, 8oyi:I, 3rgb:A, 3rgb:E, 3rgb:I, 7s4h:A, 7s4h:E, 7s4h:I, 7s4i:A, 7s4i:E, 7s4i:I, 7s4j:A, 7s4j:E, 7s4j:I, 7s4k:A, 7s4k:E, 7s4k:I, 8sqw:A, 8sqw:E, 8sqw:I, 8sr1:A, 8sr1:E, 8sr1:I, 8sr2:A, 8sr2:E, 8sr2:I, 8sr4:A, 8sr4:E, 8sr4:I, 8sr5:A, 8sr5:E, 8sr5:I, 7t4o:A, 7t4o:E, 7t4o:I, 7t4p:A, 7t4p:E, 7t4p:I, 1yew:A, 1yew:E, 1yew:I
28 1a65:A 504 60 0.1418 0.0377 0.3167 0.63 1hfu:A
29 5mgx:G 266 87 0.1791 0.0902 0.2759 2.0 5mgx:F, 5mgx:E, 5mgx:H
30 9b00:1D 275 79 0.1716 0.0836 0.2911 4.1 5a9z:AD, 5aa0:AD, 7azo:L2A, 7azo:L2B, 7azs:L2A, 7azs:L2B, 9b00:2D, 6b4v:E, 6b4v:IB, 6boh:E, 6boh:JB, 6bok:E, 6bok:HB, 6buw:RD, 6buw:YD, 6bz6:RD, 6bz6:YD, 6bz7:RD, 6bz7:YD, 6bz8:RD, 6bz8:YD, 6c5l:BD, 6c5l:DD, 6cae:1D, 6cae:2D, 6cfj:1D, 6cfj:2D, 6cfk:1D, 6cfk:2D, 6cfl:1D, 6cfl:2D, 8cvj:1D, 8cvj:2D, 8cvk:1D, 8cvk:2D, 8cvl:1D, 8cvl:2D, 5czp:YD, 5czp:RD, 6czr:1D, 6czr:2D, 5d8b:A, 5d8b:WA, 5dfe:YD, 5dfe:RD, 5dox:1D, 5dox:2D, 5doy:1D, 5doy:2D, 5e7k:11, 5e7k:19, 5e81:11, 5e81:19, 8ekb:1D, 8ekb:2D, 5el4:11, 5el4:19, 5el5:11, 5el5:19, 5el6:11, 5el6:19, 5el7:11, 5el7:19, 8ev6:1D, 8ev6:2D, 8ev7:1D, 8ev7:2D, 5f8k:1D, 5f8k:2D, 8fc1:1D, 8fc1:2D, 8fc2:1D, 8fc2:2D, 8fc3:1D, 8fc3:2D, 8fc4:1D, 8fc4:2D, 8fc5:1D, 8fc5:2D, 8fc6:1D, 8fc6:2D, 5fdu:1D, 5fdu:2D, 5fdv:1D, 5fdv:2D, 6fkr:1D, 6fkr:2D, 8fom:RD, 8fom:YD, 8fon:RD, 8fon:YD, 8g29:1D, 8g29:2D, 8g2a:1D, 8g2a:2D, 8g2b:1D, 8g2b:2D, 8g2c:1D, 8g2c:2D, 8g2d:1D, 8g2d:2D, 6gsj:11, 6gsj:19, 6gsk:11, 6gsk:19, 6gsl:11, 6gsl:19, 6gzq:C1, 6gzx:C1, 6gzx:C2, 6gzz:C1, 6gzz:C2, 5hau:1D, 5hau:2D, 5hcp:1D, 5hcp:2D, 5hcq:1D, 5hcq:2D, 5hcr:1D, 5hcr:2D, 5hd1:1D, 5hd1:2D, 5ib7:11, 5ib7:19, 5ib8:11, 5ib8:19, 5ibb:11, 5ibb:19, 5imq:a, 5imr:a, 5j30:RD, 5j30:YD, 5j3c:RD, 5j3c:YD, 5j4b:1D, 5j4b:2D, 5j4c:1D, 5j4c:2D, 5j4d:E, 5j4d:JB, 5j8b:D, 7jql:1D, 7jql:2D, 7jqm:1D, 7jqm:2D, 4l47:RD, 4l47:YD, 4l71:RD, 4l71:YD, 4lel:RD, 4lel:YD, 4lfz:RD, 4lfz:YD, 7lh5:BD, 7lh5:DD, 4lnt:RD, 4lnt:YD, 4lsk:RD, 4lsk:YD, 4lt8:RD, 4lt8:YD, 7md7:1D, 7md7:2D, 6n1d:AL02, 6n1d:BL02, 6n9e:1D, 6n9e:2D, 6n9f:1D, 6n9f:2D, 5ndj:11, 5ndj:19, 5ndk:11, 5ndk:19, 6nd5:1D, 6nd5:2D, 6nd6:1D, 6nd6:2D, 6ndk:RD, 6ndk:YD, 6nsh:RD, 6nsh:YD, 6nta:RD, 6nta:YD, 6nuo:RD, 6nuo:YD, 6nwy:RD, 6nwy:YD, 6o3m:RD, 6o3m:YD, 6o97:1D, 6o97:2D, 6of1:1D, 6of1:2D, 6of6:RD, 6of6:YD, 6oj2:RD, 6oj2:YD, 6ope:RD, 6ope:YD, 6ord:RD, 6ord:YD, 6osi:RD, 6osi:YD, 5ot7:g, 6otr:RD, 6otr:YD, 6oxa:RD, 6oxa:YD, 6oxi:RD, 6oxi:YD, 4p6f:RD, 4p6f:YD, 4p70:RD, 4p70:YD, 6q95:B, 6qnq:11, 6qnq:19, 6qnr:11, 6qnr:19, 7rq8:1D, 7rq8:2D, 7rq9:1D, 7rq9:2D, 7rqa:1D, 7rqa:2D, 7rqb:1D, 7rqb:2D, 7rqc:1D, 7rqc:2D, 7rqd:1D, 7rqd:2D, 7rqe:1D, 7rqe:2D, 8t8b:1D, 8t8b:2D, 8t8c:1D, 8t8c:2D, 4tua:RD, 4tua:YD, 4tub:RD, 4tub:YD, 4tuc:RD, 4tuc:YD, 4tud:RD, 4tud:YD, 4tue:RD, 4tue:YD, 7u2h:1D, 7u2h:2D, 7u2i:1D, 7u2i:2D, 7u2j:1D, 7u2j:2D, 6ucq:1D, 6ucq:2D, 8ud6:1D, 8ud6:2D, 8ud7:1D, 8ud7:2D, 8ud8:1D, 8ud8:2D, 6uo1:1D, 6uo1:2D, 5uq7:D, 5uq8:D, 8uvr:1D, 8uvr:2D, 8uvs:1D, 8uvs:2D, 4v4i:B, 4v4j:B, 4v4x:BD, 4v4y:BD, 4v4z:BD, 4v51:BD, 4v51:DD, 4v5a:BD, 4v5a:DD, 4v5c:BD, 4v5c:DD, 4v5d:BD, 4v5d:DD, 4v5e:BD, 4v5e:DD, 4v5f:BD, 4v5f:DD, 4v5g:BD, 4v5g:DD, 4v5j:BD, 4v5j:DD, 4v5k:BD, 4v5k:DD, 4v5l:BD, 4v5m:BD, 4v5n:BD, 4v5p:BD, 4v5p:DD, 4v5q:BD, 4v5q:DD, 4v5r:BD, 4v5r:DD, 4v5s:BD, 4v5s:DD, 4v63:BD, 4v63:DD, 4v67:BD, 4v67:DD, 4v68:BD, 4v6a:BD, 4v6a:DD, 4v6f:AD, 4v6f:DD, 4v6g:BD, 4v6g:DD, 4v7j:AD, 4v7j:BD, 4v7k:AD, 4v7k:BD, 4v7l:BD, 4v7l:DD, 4v7m:BD, 4v7m:DD, 4v7p:BC, 4v7p:CC, 4v7w:BD, 4v7w:DD, 4v7x:BD, 4v7x:DD, 4v7y:BD, 4v7y:DD, 4v7z:BD, 4v7z:DD, 4v83:BC, 4v83:DC, 4v84:BC, 4v84:DC, 4v87:AD, 4v87:DD, 4v8a:AD, 4v8a:BD, 4v8b:BD, 4v8b:DD, 4v8c:AD, 4v8c:BD, 4v8d:BD, 4v8d:DD, 4v8e:AD, 4v8e:CD, 4v8f:AD, 4v8f:DD, 4v8g:BD, 4v8g:DD, 4v8h:BD, 4v8h:DD, 4v8i:BD, 4v8i:DD, 4v8j:BD, 4v8j:DD, 4v8n:BD, 4v8n:DD, 4v8o:BD, 4v8q:AD, 4v8u:BD, 4v8u:DD, 4v8x:BD, 4v8x:DD, 5v8i:1D, 5v8i:2D, 4v90:BD, 4v95:BD, 4v95:DD, 4v97:BD, 4v97:DD, 4v9a:BD, 4v9a:DD, 4v9b:BD, 4v9b:DD, 4v9h:BD, 4v9i:BD, 4v9i:DD, 4v9j:BD, 4v9j:DD, 4v9k:BD, 4v9k:DD, 4v9l:BD, 4v9l:DD, 4v9m:BD, 4v9m:DD, 4v9n:BD, 4v9n:DD, 4v9q:AD, 4v9q:CD, 4v9r:BD, 4v9r:DD, 4v9s:BD, 4v9s:DD, 5vp2:1D, 5vp2:2D, 5vpo:RD, 5vpo:YD, 5vpp:RD, 5vpp:YD, 8vtu:1D, 8vtu:2D, 8vtv:1D, 8vtv:2D, 8vtw:1D, 8vtw:2D, 8vtx:1D, 8vtx:2D, 8vty:1D, 8vty:2D, 1vvj:RD, 1vvj:YD, 1vy4:BD, 1vy4:DD, 1vy5:BD, 1vy5:DD, 1vy6:BD, 1vy6:DD, 1vy7:BD, 1vy7:DD, 4w29:BD, 4w29:DD, 4w2e:D, 4w2f:BD, 4w2f:DD, 4w2g:BD, 4w2g:DD, 4w2h:BD, 4w2h:DD, 4w2i:BD, 4w2i:DD, 4w4g:RD, 4w4g:YD, 5w4k:1D, 5w4k:2D, 5wis:1D, 5wis:2D, 5wit:1D, 5wit:2D, 4wpo:AD, 4wpo:CD, 4wq1:11, 4wq1:19, 4wqf:AD, 4wqf:CD, 4wqr:11, 4wqr:19, 4wqu:AD, 4wqu:CD, 4wqy:AD, 4wqy:CD, 4wr6:11, 4wr6:19, 4wra:11, 4wra:19, 4wro:11, 4wsd:11, 4wsd:19, 4wsm:11, 4wsm:19, 4wt1:11, 4wt1:19, 4wt8:CB, 4wt8:DB, 4wu1:11, 4wu1:19, 4wzd:11, 4wzd:19, 4wzo:11, 4wzo:19, 4xej:AL02, 4xej:BL02, 6xhv:1D, 6xhv:2D, 6xhw:1D, 6xhw:2D, 6xhx:1D, 6xhx:2D, 6xhy:1D, 6xhy:2D, 6xqd:1D, 6xqd:2D, 6xqe:1D, 6xqe:2D, 4y4o:1D, 4y4o:2D, 4y4p:1D, 4y4p:2D, 4ypb:RD, 4ypb:YD, 4yzv:RD, 4yzv:YD, 4z3s:1D, 4z3s:2D, 4z8c:1D, 4z8c:2D, 4zer:1D, 4zer:2D, 5zlu:Z, 4zsn:RD, 4zsn:YD
31 4pqg:A 506 39 0.0896 0.0237 0.3077 4.6 4pqg:B
32 6cxh:A 382 92 0.1493 0.0524 0.2174 4.8 7s4l:A, 7s4l:D, 7s4l:E
33 2vh9:A 266 86 0.1791 0.0902 0.2791 4.9 2vh9:B
34 6w3z:C 352 43 0.1119 0.0426 0.3488 6.4 6w3z:A, 6w3z:D, 6w3z:B
35 2vvf:A 269 34 0.1119 0.0558 0.4412 6.7 2vvf:B, 2vvf:C, 2vvf:D, 2vvf:E, 2vvf:F, 2w0c:A, 2w0c:B, 2w0c:C, 2w0c:D, 2w0c:E, 2w0c:F, 2w0c:G, 2w0c:H, 2w0c:I, 2w0c:J
36 7ntl:A 220 32 0.0896 0.0545 0.3750 7.0
37 7s3d:A 749 85 0.1642 0.0294 0.2588 7.5 7s3d:G, 7s3d:a
38 8an2:AAA 1040 57 0.1194 0.0154 0.2807 8.6 8an3:AAA, 7zcx:AAA

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218