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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
NAMSVVILAAGKGTRMYSDLPKVLHTLAGKAMVQHVIDAANELGAAHVHLVYGHGGDLLKQALKDDNLNWVLQAEQLGTG
HAMQQAAPFFADDEDILMLYGDVPLISVETLQRLRDAKPQGGIGLLTVKLDDPTGYGRITRENGKVTGIVEHKDATDEQR
QIQEINTGILIANGADMKRWLAKLTNNNAQGEYYITDIIALAYQEGREIVAVHPQRLSEVEGVNNRLQLSRLERVYQSEQ
AEKLLLAGVMLRDPARFDLRGTLTHGRDVEIDTNVIIEGNVTLGHRVKIGTGCVIKNSVIGDDCEISPYTVVEDANLAAA
CTIGPFARLRPGAELLEGAHVGNFVEMKKARLGKGSKAGHLTYLGDAEIGDNVNIGAGTITCNYDGANKFKTIIGDDVFV
GSDTQLVAPVTVGKGATIAAGTTVTRNVGENALAISRVPQTQKEGWRRP

The query sequence (length=449) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 2oi6:B 452 449 1.0000 0.9934 1.0000 0.0 4aa7:A, 4aa7:B, 1fwy:A, 1fwy:B, 1hv9:A, 1hv9:B, 2oi5:A, 2oi5:B, 2oi6:A, 2oi7:A, 2oi7:B, 3twd:A, 3twd:B
2 4fce:A 441 446 0.8129 0.8277 0.8184 0.0
3 4e1k:A 450 448 0.6860 0.6844 0.6875 0.0 4knr:A, 4knx:A, 4kpx:A, 4kpz:A, 4kql:A, 2v0i:A, 2v0j:A, 2v0k:A, 2v0l:A, 2vd4:A, 2w0v:A, 2w0w:A
4 1hm8:A 458 445 0.4053 0.3974 0.4090 2.21e-111 4aaw:A, 4ac3:A, 1g97:A, 1hm8:B, 1hm9:A, 1hm9:B, 7kr9:A
5 3d8v:A 478 460 0.3942 0.3703 0.3848 2.23e-93 3dj4:A, 4g3p:A, 4g3q:A, 4g3s:A, 4g87:A, 6ge9:A, 4hcq:A, 4k6r:A, 2qkx:A, 3spt:A, 3st8:A
6 3foq:A 439 460 0.3519 0.3599 0.3435 4.85e-68
7 2ggq:A 401 450 0.2494 0.2793 0.2489 5.86e-20 5z09:A, 5z09:B, 5z09:C, 5z09:D
8 7x8k:B 367 401 0.2027 0.2480 0.2269 4.94e-09 7x8k:A, 7x8k:D
9 7d72:K 360 406 0.2049 0.2556 0.2266 1.14e-07 7d72:I, 7d72:E, 7d72:F, 7d72:G, 7d72:H, 7d72:J, 7d72:L, 7d73:E, 7d73:F, 7d73:G, 7d73:I, 7d73:J, 7d73:K, 7d73:L, 7d73:H, 7d74:E, 7d74:F, 7d74:G, 7d74:H, 7d74:I, 7d74:J, 7d74:K, 7d74:L
10 4mzu:F 294 154 0.0846 0.1293 0.2468 1.76e-06 4mzu:A, 4mzu:C, 4mzu:E, 4mzu:B, 4mzu:D, 4mzu:G, 4mzu:I, 4mzu:K, 4mzu:H, 4mzu:J, 4mzu:L, 4zu4:A, 4zu4:B, 4zu4:C
11 4mzu:F 294 87 0.0601 0.0918 0.3103 2.4 4mzu:A, 4mzu:C, 4mzu:E, 4mzu:B, 4mzu:D, 4mzu:G, 4mzu:I, 4mzu:K, 4mzu:H, 4mzu:J, 4mzu:L, 4zu4:A, 4zu4:B, 4zu4:C
12 6jq8:A 225 93 0.0601 0.1200 0.2903 4.11e-06
13 7d72:A 407 352 0.1871 0.2064 0.2386 6.50e-06 7d72:B, 7d72:C, 7d72:D, 7d73:A, 7d73:B, 7d73:C, 7d73:D, 7d74:A, 7d74:D, 7d74:B, 7d74:C
14 7whs:A 366 410 0.1915 0.2350 0.2098 3.33e-05 7whs:B, 7whs:C, 7whs:D, 7whs:E, 7whs:F, 7wht:A, 7wht:B, 7wht:C, 7wht:D, 7wht:E, 7wht:F
15 4ihh:E 340 159 0.1069 0.1412 0.3019 8.50e-05 4ihf:D, 4ihf:E, 4ihf:F, 4ihf:A, 4ihf:B, 4ihf:C, 4ihg:E, 4ihg:C, 4ihg:B, 4ihg:D, 4ihh:A, 4ihh:C, 4ihh:B, 4ihh:D, 4ihh:F, 6p83:A, 6p83:C, 6p83:B, 6p84:A, 6p84:C, 6p84:B, 6p85:A, 6p85:C, 6p85:B, 6p86:A, 6p86:C, 6p86:B, 6p87:A, 6p87:C, 6p87:B, 6p88:A, 6p88:C, 6p88:B, 6p89:A, 6p89:C, 6p89:B, 6p8a:A, 6p8a:C, 6p8a:B, 6p8b:A, 6p8b:C, 6p8b:B
16 7s3u:A 145 154 0.0802 0.2483 0.2338 2.50e-04 7s3w:A, 7s41:A, 7s42:A, 7s43:A, 7s44:A, 7s45:A
17 2ux8:A 255 197 0.1114 0.1961 0.2538 5.65e-04 2ux8:H
18 1khr:A 206 138 0.0824 0.1796 0.2681 0.001 3dho:A, 3dho:C, 3dho:B, 3dho:D, 3dho:F, 3dho:E, 1khr:B, 1khr:C, 1khr:D, 1khr:E, 1khr:F, 1kk4:A, 1kk4:B, 1kk4:C, 1kk4:D, 1kk4:E, 1kk4:F, 1mr9:A, 1mr9:C, 1mr9:B, 1mr9:X, 1mr9:Z, 1mr9:Y, 1mrl:A, 1mrl:B, 1mrl:C
19 6pxa:E 221 37 0.0356 0.0724 0.4324 0.004 6pxa:A, 6pxa:B, 6pxa:C, 6pxa:D, 6pxa:F, 6pxa:G, 6pxa:H, 6pxa:I, 6pxa:J, 6pxa:K, 6pxa:L, 5ux9:A, 5ux9:B, 5ux9:C, 5ux9:D
20 2ux8:G 288 182 0.1069 0.1667 0.2637 0.005 2ux8:B, 2ux8:C, 2ux8:D, 2ux8:E, 2ux8:F
21 4hus:A 212 41 0.0379 0.0802 0.4146 0.006 4hur:A, 4hur:B, 4hur:C, 4hus:C, 6x3c:A, 6x3c:F, 6x3c:B, 6x3c:C, 6x3c:D, 6x3c:E, 6x3j:A, 6x3j:B, 6x3j:D, 6x3j:C, 6x3j:E, 6x3j:F
22 5u2k:A 190 99 0.0690 0.1632 0.3131 0.006 5v0z:A, 5v0z:C, 5v0z:B, 3v4e:A, 3v4e:C, 3v4e:B
23 4y7u:A 224 144 0.0935 0.1875 0.2917 0.007 4y7v:A
24 8j40:A 209 42 0.0334 0.0718 0.3571 0.010
25 8b6d:A 291 251 0.1292 0.1993 0.2311 0.011 8b68:A, 8b6d:B
26 6pub:A 210 37 0.0356 0.0762 0.4324 0.011 6u9c:A, 6u9c:B, 6u9c:C
27 1kru:A 201 128 0.0780 0.1741 0.2734 0.021 1kqa:A, 1kqa:B, 1kqa:C, 1krr:A, 1krr:B, 1krr:C, 1kru:B, 1kru:C, 1krv:A, 1krv:C, 1krv:B
28 2pa4:B 299 252 0.1403 0.2107 0.2500 0.021 2pa4:A, 2pa4:C, 2pa4:D
29 1wvc:A 254 260 0.1247 0.2205 0.2154 0.023 1tzf:A
30 3mqg:C 192 152 0.0869 0.2031 0.2566 0.034 3mqg:A, 3mqg:B, 3mqg:D, 3mqg:E, 3mqg:F, 3mqh:A, 3mqh:C, 3mqh:B, 3mqh:D, 3mqh:F, 3mqh:E
31 4zdq:A 230 136 0.0824 0.1609 0.2721 0.037 4zdq:D
32 4r37:A 255 128 0.0757 0.1333 0.2656 0.048
33 4r37:A 255 82 0.0535 0.0941 0.2927 0.18
34 8f73:E 281 126 0.0624 0.0996 0.2222 0.063 8f73:A, 8f73:B, 8f73:C, 8f73:D, 8f73:F, 8f73:G, 8f73:H
35 4isx:A 186 42 0.0312 0.0753 0.3333 0.070 4isx:B
36 6jlz:I 430 385 0.1759 0.1837 0.2052 0.10
37 6jlz:I 430 95 0.0668 0.0698 0.3158 0.26
38 3k8d:A 246 133 0.0780 0.1423 0.2632 0.13 3k8d:B, 3k8d:C, 3k8d:D
39 1h5s:B 291 219 0.1180 0.1821 0.2420 0.16 1h5r:A, 1h5r:B, 1h5r:C, 1h5r:D, 1h5s:A, 1h5s:D, 1h5s:C, 1h5t:A, 1h5t:D, 1h5t:B, 1h5t:C, 1iim:A, 1iim:B, 1iin:A, 1iin:B, 1iin:C, 1iin:D, 1mp3:A, 1mp3:B, 1mp4:A, 1mp4:B, 1mp5:A, 1mp5:B, 1mp5:C, 1mp5:D, 3pkp:A, 3pkp:B, 3pkp:C, 3pkp:D, 3pkp:I, 3pkp:J, 3pkp:K, 3pkp:L, 3pkq:A, 3pkq:B, 3pkq:C, 3pkq:D
40 3pmo:A 357 176 0.1091 0.1373 0.2784 0.23 6uec:A
41 4n69:A 243 96 0.0668 0.1235 0.3125 0.27 4n69:B, 4n6b:A, 4n6b:E, 4n6b:B, 4n6b:C, 4n6b:D, 4n6b:F
42 7bw9:A 280 116 0.0668 0.1071 0.2586 0.31 7bw9:B, 7bw9:C
43 4eaa:A 210 125 0.0757 0.1619 0.2720 0.33 4ea7:A, 4ea8:A, 4ea9:A, 4eab:A
44 4eaa:A 210 74 0.0579 0.1238 0.3514 0.37 4ea7:A, 4ea8:A, 4ea9:A, 4eab:A
45 6wye:A 261 84 0.0557 0.0958 0.2976 0.37 7ra4:A, 7ra4:C, 7ra4:B, 6wye:C, 6wye:B, 6wye:D, 6wye:F, 6wye:E
46 3hl3:A 246 211 0.1091 0.1992 0.2322 0.40 4ecm:A
47 4ho9:A 294 215 0.1091 0.1667 0.2279 0.43 4ho3:A, 4ho4:A, 4ho5:A, 4ho5:B, 4ho6:A, 4ho8:A, 4ho8:B, 4ho8:C, 4ho8:D, 4ho9:B, 4hoc:A, 4hoc:B
48 2iu8:A 346 153 0.0802 0.1040 0.2353 0.61 2iu8:B, 2iu8:C, 2iu9:A, 2iu9:B, 2iu9:C, 2iua:A, 2iua:C
49 3nz2:J 185 76 0.0512 0.1243 0.3026 0.68 3ect:A, 3nz2:A, 3nz2:C, 3nz2:B, 3nz2:D, 3nz2:E, 3nz2:F, 3nz2:G, 3nz2:H, 3nz2:I, 3nz2:K, 3nz2:L
50 3vcy:A 419 157 0.0980 0.1050 0.2803 0.84 3vcy:B, 3vcy:C, 3vcy:D
51 3r3r:A 184 138 0.0869 0.2120 0.2826 0.87
52 2fko:A 173 116 0.0668 0.1734 0.2586 0.87 1v3w:A, 1v67:A
53 3r8y:A 203 111 0.0824 0.1823 0.3333 0.92 3r8y:C, 3r8y:D, 3r8y:F
54 7aqq:y 268 59 0.0468 0.0784 0.3559 0.95 7ar7:y, 7ar8:y, 7arb:y, 8bef:y, 8bpx:y, 8bq5:y, 8bq6:y
55 4eqy:G 260 45 0.0401 0.0692 0.4000 1.1
56 4hzd:A 250 94 0.0646 0.1160 0.3085 1.2 4hzc:F, 4hzc:J
57 3tio:F 177 122 0.0757 0.1921 0.2787 1.3 3tio:A, 3tio:B, 3tio:C, 3tio:D, 3tio:E, 3tis:A, 3tis:B, 3tis:C
58 3tio:F 177 100 0.0579 0.1469 0.2600 3.5 3tio:A, 3tio:B, 3tio:C, 3tio:D, 3tio:E, 3tis:A, 3tis:B, 3tis:C
59 4e7b:A 419 73 0.0490 0.0525 0.3014 1.7 1a2n:A, 4e7b:B, 4e7b:C, 4e7b:D, 4e7c:A, 4e7c:B, 4e7d:A, 4e7e:A, 4e7e:D, 4e7f:A, 1eyn:A, 3iss:A, 3iss:B, 3iss:C, 3iss:D, 3iss:E, 3iss:F, 3iss:G, 3iss:H, 3iss:I, 3iss:J, 3iss:K, 3iss:L, 3kqa:A, 3kqa:B, 3kqa:C, 3kqa:D, 3kqj:A, 3kr6:A, 3lth:A, 1q3g:A, 1q3g:B, 1q3g:C, 1q3g:D, 1q3g:E, 1q3g:F, 1q3g:G, 1q3g:H, 1q3g:I, 1q3g:J, 1q3g:K, 1q3g:L, 1q3g:W, 1q3g:X, 1q3g:Y, 1q3g:Z, 1ryw:A, 1ryw:B, 1ryw:C, 1ryw:D, 1ryw:E, 1ryw:F, 1ryw:G, 1ryw:H, 3su9:A, 3swa:A, 3swa:B, 3swd:A, 3swd:B, 3swd:C, 3swd:D, 3swd:E, 3swd:F, 3swd:G, 3swd:H, 3swd:I, 3swd:J, 3swd:K, 3swd:L, 3swi:A, 3swq:A, 1uae:A, 3upk:A, 3v4t:A, 3v4t:B, 3v4t:C, 3v4t:D, 3v4t:E, 3v4t:F, 3v4t:G, 3v4t:H, 1ybg:A, 1ybg:B, 1ybg:C, 1ybg:D, 2z2c:A, 2z2c:B, 2z2c:C, 2z2c:D
60 3igj:C 188 40 0.0334 0.0798 0.3750 1.7 3igj:A, 3igj:B
61 2xat:A 208 42 0.0334 0.0721 0.3571 1.7
62 1vpa:A 221 30 0.0245 0.0498 0.3667 2.0 1vpa:B
63 4r7u:C 419 188 0.1002 0.1074 0.2394 2.8 4r7u:A, 4r7u:B, 4r7u:D
64 3vnp:A 171 63 0.0468 0.1228 0.3333 2.9 3vnp:B, 3vnp:C
65 1vh3:B 246 156 0.0913 0.1667 0.2628 2.9 1vh3:A
66 5n1q:F 260 36 0.0312 0.0538 0.3889 3.2 5n1q:C
67 7ad3:F 318 74 0.0445 0.0629 0.2703 3.5
68 5i1f:A 290 191 0.0980 0.1517 0.2304 3.5
69 1jyl:A 228 62 0.0423 0.0833 0.3065 3.5 1jyl:B, 1jyl:C, 1jyl:D
70 4c20:B 605 37 0.0356 0.0264 0.4324 4.1 4c20:A, 4c21:A, 4c21:B, 4c22:A, 4c22:B
71 8bpa:C 213 88 0.0468 0.0986 0.2386 4.1 8c60:C
72 1p8l:A 276 59 0.0445 0.0725 0.3390 4.2 1fvi:A
73 8e73:G2 258 61 0.0468 0.0814 0.3443 4.8 6x89:G2
74 4iok:A 557 52 0.0445 0.0359 0.3846 4.9 1fp7:A, 1fpm:A, 1fpm:B, 4iok:B, 4iol:A, 4iol:B, 4jjz:A, 4jjz:B, 4jki:A, 3qus:A, 3qus:B
75 2q2t:A 293 59 0.0445 0.0683 0.3390 5.0 2q2u:A, 2q2u:B, 2q2u:C, 2q2u:D
76 8ban:C 251 71 0.0557 0.0996 0.3521 5.0 8ban:D, 8bbj:C, 8bbj:D
77 3p47:A 270 69 0.0490 0.0815 0.3188 5.9 3q1x:A
78 7l7y:AAA 217 105 0.0668 0.1382 0.2857 5.9 7l7z:AAA, 7l81:AAA, 7l82:AAA
79 2xwl:B 222 36 0.0290 0.0586 0.3611 7.2 2xwl:A, 2xwm:A, 2xwm:B
80 3rsb:B 185 35 0.0312 0.0757 0.4000 8.9 3rsb:A, 3rsb:C, 3rsb:D
81 2xwn:B 227 33 0.0223 0.0441 0.3030 9.7 3okr:D, 3q7u:A, 3q7u:B, 3q80:A, 3q80:B, 2xwn:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218