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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MYGLVNKAIQDMISKHHGEDTWEAIKQKAGLEDIDFFVGMEAYSDDVTYHLVGAASEVLGKPAEEWWIAFGEYWVTYTSE
EGYGELLASAGDSLPEFMENLDNLHARVGLSFPQLRPPAFECQHTSSKSMELHYQSTRCGLAPMVLGLLHGLGKRFQTKV
EVTQTAFRETGEDHDIFSIKYED

The query sequence (length=183) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6dxi:A 189 182 0.9836 0.9524 0.9890 2.27e-134 4iae:A, 4iae:B, 4iah:A, 4iah:B, 4iam:A, 4iam:B, 5ixr:A, 5ixr:B, 5ixv:A, 5ixv:B, 5ixw:A, 5ixw:B, 5ixx:A, 5ixx:B, 5ixz:A, 5ixz:B, 4jqh:A, 4jqh:B, 3l6j:A, 3l6j:B, 7lgk:A, 7lgk:B, 6mx5:A, 2o09:A, 2o09:B, 2o0c:A, 2o0c:B, 2o0g:A, 2o0g:B, 3tf8:A, 3tf8:B, 3tf9:A, 3tf9:B, 3tfa:A, 3tfa:B, 3tfd:A, 3tfd:B, 3tfe:A, 3tfe:B, 3tff:A, 3tff:B, 3tfg:A, 3tfg:B
2 6pas:B 576 169 0.3224 0.1024 0.3491 6.61e-30 6pat:B
3 8hbh:B 577 182 0.3388 0.1075 0.3407 3.76e-29 7d9r:B, 7d9s:B, 7d9t:B, 7d9u:B, 8hbe:B, 8hbf:B, 6jt0:B, 6jt1:B, 6jt2:B, 5mnw:A
4 6ocv:A 190 180 0.2568 0.2474 0.2611 4.23e-12 6wqe:A
5 4u99:A 187 183 0.2077 0.2032 0.2077 1.23e-08 2kii:A, 2kil:A, 4u99:B, 4u9b:A, 4u9g:A, 4u9g:B, 4u9j:A, 4u9j:B, 4u9k:A, 4u9k:B
6 1xbn:A 195 171 0.2404 0.2256 0.2573 8.43e-06 6cww:A, 6cww:B, 3eee:A, 3eee:B, 3eee:C, 3eee:D, 4fdk:A, 4fdk:B, 3iqb:A, 4it2:A, 4it2:B, 5jru:A, 5jru:B, 5jru:C, 5jru:D, 5jru:E, 5jru:F, 5jrv:A, 5jrv:B, 5jrx:A, 5jrx:B, 3lah:A, 3lah:B, 3lai:A, 3lai:B, 3lai:C, 3m0b:A, 3nvr:A, 3nvr:B, 3nvu:A, 3nvu:B, 3sj5:A, 3sj5:B, 3tf0:A, 3tf0:B, 3tf1:A, 3tf1:B, 1u4h:A, 1u4h:B, 1u55:A, 1u55:B, 1u56:A, 1u56:B
7 6bdd:A 185 172 0.1913 0.1892 0.2035 1.48e-05 6bde:A
8 4g38:A 449 74 0.1202 0.0490 0.2973 1.8 4htr:A
9 2gep:A 472 44 0.0765 0.0297 0.3182 2.2 1aop:A, 2aop:A, 3aop:A, 4aop:A, 5aop:A, 6c3m:A, 6c3x:A, 6c3y:A, 6c3z:A, 4g39:A, 3geo:A, 4gep:A, 5gep:A, 6gep:A, 7gep:A, 8gep:A
10 5ik2:E 462 72 0.1202 0.0476 0.3056 3.0 5hkk:D, 5hkk:E, 5hkk:F, 5hkk:L, 5hkk:M, 5hkk:N, 5ik2:D, 5ik2:F, 5ik2:L, 5ik2:M, 5ik2:N
11 3g5i:A 305 63 0.0984 0.0590 0.2857 3.9 3g5i:B, 3g5i:C, 3g5i:D, 1yoe:A
12 6d0j:B 396 38 0.0710 0.0328 0.3421 4.4 6d0j:A, 6d0k:A, 6d0k:B, 6d0n:A, 6d0n:B
13 6wku:A 677 31 0.0710 0.0192 0.4194 7.4
14 6wku:A 677 40 0.0874 0.0236 0.4000 7.6
15 5yna:A 1055 37 0.0765 0.0133 0.3784 7.8 2fgz:A, 2fh6:A, 2fh8:A, 2fhb:A, 2fhc:A, 2fhf:A, 6j33:A, 6j33:B, 6j34:A, 6j35:A, 6j35:B, 6j4h:A, 5yn2:A, 5yn7:A, 5ync:A, 5ynd:A, 5yne:A, 5ynh:A, 2yoc:A, 2yoc:B
16 3sm4:C 229 42 0.0765 0.0611 0.3333 8.2 3slp:A, 3slp:B, 3slp:C, 3sm4:A, 3sm4:B, 4wuz:A, 4wuz:B, 4wuz:C
17 1e4e:A 341 25 0.0601 0.0323 0.4400 8.4 1e4e:B
18 6mpx:A 673 31 0.0710 0.0193 0.4194 8.9 1t61:C, 1t61:F
19 6mpx:A 673 31 0.0710 0.0193 0.4194 8.9 1t61:C, 1t61:F

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218