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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MVPPINCIFNFLQQQTPVTIWLFEQIGIRIKGKIVGFDEFMNVVIDEAVEIPVEKGTPLGKILLKGDNITLITS

The query sequence (length=74) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7b9v:p 77 77 1.0000 0.9610 0.9610 2.64e-46 7b9v:e, 6bk8:c, 7dco:i, 6exn:p, 6exn:e, 6g90:e, 6g90:w, 5gan:p, 5gao:p, 5gm6:i, 5gmk:i, 5gmk:u, 6j6g:i, 6j6g:u, 6j6h:i, 6j6h:u, 6j6n:i, 6j6n:u, 6j6q:i, 6j6q:u, 5mps:e, 5mq0:e, 6n7p:O, 6n7r:O, 6n7x:O, 5nrl:w, 5nrl:p, 5nrl:e, 7oqb:w, 7oqc:e, 7oqe:w, 8w2o:O, 5wsg:i, 5wsg:G, 5y88:b, 5y88:i, 5ylz:b, 5ylz:i, 5zwm:T, 5zwm:i, 5zwn:e, 5zwo:T, 5zwo:i
2 3jb9:H 76 75 0.6351 0.6184 0.6267 8.67e-30 3jb9:m
3 7abg:j 81 76 0.5405 0.4938 0.5263 5.11e-26 7a5p:j, 7a5p:e, 7abi:j, 6ah0:c, 6ahd:e, 7b0y:g, 8c6j:p, 8c6j:e, 8ch6:i, 8ch6:1, 7dvq:e, 7dvq:l, 9fmd:l, 9fmd:e, 8h6e:5e, 8h6e:4e, 8h6j:5e, 8h6j:4e, 8h6k:5e, 8h6l:5e, 8i0p:e, 8i0p:j, 8i0r:e, 8i0r:j, 8i0s:e, 8i0s:j, 8i0t:e, 8i0t:j, 8i0u:e, 8i0u:j, 8i0v:e, 8i0v:j, 8i0w:e, 8i0w:l, 6icz:e, 6id0:e, 6id1:e, 5mqf:j, 5mqf:c, 5o9z:j, 4pjo:E, 4pjo:e, 4pjo:S, 4pjo:s, 8q7q:e, 8q7v:e, 8q7w:e, 8q7x:e, 6qdv:p, 6qdv:e, 8qo9:2e, 8qo9:5e, 8qo9:4e, 7qtt:i, 6qw6:4e, 6qw6:5e, 6qx9:1e, 6qx9:5e, 6qx9:2e, 6qx9:4e, 8qxd:2e, 8qxd:4e, 8qzs:5e, 8qzs:2e, 8qzs:4e, 8r08:1e, 8r08:2e, 8r08:4e, 8r09:2e, 8r09:5e, 8r09:4e, 8r0a:5e, 8r0a:2e, 8r0a:4e, 8r0b:4e, 8r0b:5e, 8rm5:2e, 8rm5:5e, 8rm5:4e, 8ro2:e, 6v4x:E, 7vpx:l, 7w59:e, 7w59:l, 7w5a:e, 7w5a:l, 7w5b:e, 7w5b:l, 4wzj:E, 4wzj:L, 4wzj:S, 4wzj:EE, 4wzj:LL, 4wzj:SS, 4wzj:EEE, 4wzj:LLL, 4wzj:SSS, 4wzj:EEEE, 4wzj:LLLL, 4wzj:SSSS, 5xjc:e, 5xjc:l, 8y6o:e, 8y6o:l, 8y6o:s, 8y7e:l, 5yzg:e, 5yzg:l, 5z56:e, 5z56:l, 5z57:e, 5z57:l, 5z58:e, 5z58:l
4 8ro0:e 80 75 0.5811 0.5375 0.5733 6.83e-25 8ro1:e
5 8ro0:n 77 45 0.2568 0.2468 0.4222 1.31e-05 8ro0:g, 8ro1:g
6 6v4x:G 77 49 0.2297 0.2208 0.3469 6.09e-05 7a5p:k, 7a5p:g, 7abg:k, 7abi:k, 6ah0:n, 6ahd:S, 6ahd:f, 6ahd:n, 7b0y:h, 8c6j:r, 8c6j:g, 8ch6:m, 8ch6:9, 7dvq:g, 7dvq:n, 7evo:d, 9fmd:n, 9fmd:g, 8h6e:5f, 8h6e:4f, 8h6e:2f, 8h6j:5f, 8h6j:4f, 8h6j:2f, 8h6k:5f, 8h6k:4f, 8h6k:2f, 8h6l:5f, 8h6l:4f, 8h6l:2f, 8hk1:d, 8i0p:k, 8i0r:k, 8i0s:f, 8i0s:k, 8i0t:k, 8i0u:f, 8i0u:k, 8i0v:k, 8i0w:n, 6icz:g, 6id0:g, 6id1:g, 5mqf:k, 5mqf:d, 5o9z:k, 4pjo:G, 4pjo:g, 4pjo:U, 4pjo:u, 8q7q:g, 8q7v:g, 8q7w:g, 8q7x:g, 8q91:n, 6qdv:r, 6qdv:g, 8qo9:2g, 8qo9:4g, 7qtt:m, 6qw6:4g, 6qw6:5g, 6qx9:1g, 6qx9:5g, 6qx9:2g, 6qx9:4g, 8qxd:2g, 8qxd:4g, 8qxd:5g, 8qzs:5g, 8qzs:2g, 8qzs:4g, 8r08:1g, 8r08:2g, 8r08:4g, 8r08:5g, 8r09:2g, 8r09:5g, 8r09:4g, 8r0a:5g, 8r0a:2g, 8r0a:4g, 8r0b:2g, 8r0b:4g, 8r0b:5g, 8rc0:n, 8rm5:2g, 8rm5:5g, 8rm5:4g, 8ro2:g, 7vpx:d, 7vpx:n, 7w59:g, 7w59:n, 7w5a:g, 7w5a:n, 7w5b:g, 7w5b:n, 4wzj:G, 4wzj:N, 4wzj:U, 4wzj:GG, 4wzj:NN, 4wzj:UU, 4wzj:GGG, 4wzj:NNN, 4wzj:UUU, 4wzj:GGGG, 4wzj:NNNN, 4wzj:UUUU, 5xjc:g, 5xjc:n, 6y53:k, 6y5q:k, 8y6o:g, 8y6o:n, 8y6o:u, 8y7e:n, 5yzg:g, 5yzg:n, 5z56:g, 5z56:n, 5z57:g, 5z57:n, 5z58:g, 5z58:n
7 1m8v:A 72 71 0.2838 0.2917 0.2958 0.001 1m8v:M, 1m8v:C, 1m8v:K, 1m8v:F, 1m8v:H, 1m8v:E, 1m8v:I, 1m8v:D, 1m8v:J, 1m8v:B, 1m8v:L, 1m8v:G, 1m8v:N
8 1loj:C 77 72 0.3514 0.3377 0.3611 0.001 1loj:A, 1loj:B, 1loj:D, 1loj:E, 1loj:F, 1loj:G, 1loj:H, 1loj:I, 1loj:J, 1loj:K, 1loj:L, 1loj:M, 1loj:N
9 5mkn:d 72 60 0.2568 0.2639 0.3167 0.001 5mki:C, 5mki:D, 5mki:E, 5mki:F, 5mki:G, 5mki:I, 5mki:J, 5mki:K, 5mki:L, 5mkn:A, 5mkn:G, 5mkn:B, 5mkn:C, 5mkn:D, 5mkn:E, 5mkn:F, 5mkn:H, 5mkn:I, 5mkn:J, 5mkn:K, 5mkn:L, 5mkn:M, 5mkn:N, 5mkn:O, 5mkn:P, 5mkn:Q, 5mkn:R, 5mkn:T, 5mkn:U, 5mkn:V, 5mkn:W, 5mkn:X, 5mkn:Y, 5mkn:Z, 5mkn:a, 5mkn:b
10 3jb9:E 98 42 0.1892 0.1429 0.3333 0.018 3jb9:b
11 6bk8:f 80 43 0.2297 0.2125 0.3953 0.019 6bk8:k, 7dco:a, 7dco:h, 6exn:k, 6exn:b, 6g90:s, 5gam:b, 5gan:k, 5gan:b, 5gao:k, 5gm6:k, 5gmk:k, 5gmk:s, 3jcm:S, 5lj3:b, 5lj5:b, 5mps:b, 5mq0:k, 5mq0:b, 5nrl:s, 5nrl:k, 5nrl:b, 7oqb:s, 7oqe:s, 5wsg:k, 5wsg:F, 5y88:a, 5y88:h, 5ylz:a, 5ylz:h, 5zwm:P, 5zwm:a, 5zwm:h, 5zwo:a, 5zwo:P
12 6qw6:68 95 59 0.2432 0.1895 0.3051 0.030 6ahd:z, 8h6e:6g, 8h6j:6g, 8h6k:6g, 8h6l:6g, 6qx9:68, 8qxd:68, 8r08:68, 8r09:68, 8r0a:68, 8r0b:68, 8rm5:68
13 8y6o:q 104 47 0.1757 0.1250 0.2766 0.052 7a5p:h, 7abg:a, 7abi:a, 6ah0:k, 6ah0:P, 6ahd:P, 6ahd:k, 8ch6:l, 8ch6:4, 7dvq:k, 8h6e:2c, 8h6j:2c, 8h6k:4c, 8h6k:2c, 8h6l:4c, 8h6l:2c, 8i0w:k, 6id0:k, 6id1:k, 5o9z:h, 5o9z:a, 4pjo:R, 7qtt:l, 8qzs:42, 7w59:k, 7w5a:k, 7w5b:k, 5xjc:k, 8y7e:k, 5yzg:k, 5z56:k, 5z57:k, 5z58:k
14 6exn:r 75 26 0.1622 0.1600 0.4615 0.068 7b9v:r, 7b9v:g, 6bk8:d, 7dco:k, 6exn:g, 6g90:g, 6g90:y, 5gam:g, 5gan:r, 5gan:g, 5gao:r, 5gm6:j, 5gmk:j, 5gmk:x, 6j6g:j, 6j6g:x, 6j6h:j, 6j6h:x, 6j6n:j, 6j6n:x, 6j6q:j, 6j6q:x, 5lj3:g, 5lj5:g, 5mps:g, 5mq0:g, 6n7p:Q, 6n7r:Q, 6n7x:Q, 5nrl:y, 5nrl:r, 5nrl:g, 7oqb:y, 7oqc:g, 7oqe:y, 8w2o:Q, 5wsg:j, 5wsg:K, 5y88:d, 5y88:k, 5ylz:d, 5ylz:k, 5zwm:V, 5zwm:k, 5zwn:g, 5zwo:k
15 6ppn:H 94 71 0.2432 0.1915 0.2535 0.079 6ppn:P, 6ppp:H, 6ppp:P
16 3jb9:J 73 47 0.1486 0.1507 0.2340 0.099 3jb9:o
17 6n7p:M 107 77 0.2568 0.1776 0.2468 0.15 7b9v:m, 7b9v:j, 6bk8:a, 7dco:n, 6exn:m, 6exn:j, 6g90:i, 6g90:u, 5gam:j, 5gan:m, 5gan:j, 5gao:m, 5gm6:g, 5gmk:g, 5gmk:e, 6j6g:g, 6j6g:e, 6j6h:g, 6j6h:e, 6j6n:g, 6j6n:e, 6j6q:g, 6j6q:e, 3jcm:Q, 3jcm:U, 5lj3:j, 5lj3:m, 5lj5:j, 5lj5:m, 5mps:j, 5mq0:j, 6n7r:M, 6n7x:M, 5nrl:u, 5nrl:m, 5nrl:i, 7oqb:u, 7oqc:i, 7oqe:i, 7oqe:u, 8w2o:M, 5wsg:g, 5wsg:W, 5y88:g, 5y88:n, 5ylz:g, 5ylz:n, 5zwm:R, 5zwm:c, 5zwm:n, 5zwn:c, 5zwo:c, 5zwo:R, 5zwo:n
18 8ro0:d 94 44 0.1757 0.1383 0.2955 0.17 8ro1:d
19 3swn:A 76 55 0.1757 0.1711 0.2364 0.18 6ppq:E, 6ppv:E, 3swn:D, 3swn:P, 3swn:S
20 4m7a:F 66 36 0.1892 0.2121 0.3889 0.19
21 4v2s:A 71 29 0.1486 0.1549 0.3793 0.23 7ogm:D, 4v2s:B, 4v2s:C, 4v2s:D, 4v2s:E, 4v2s:F, 2ylc:A
22 6n7r:K 124 35 0.1892 0.1129 0.4000 0.25 7b9v:k, 7b9v:b, 6g90:b, 6j6g:k, 6j6g:s, 6j6h:k, 6j6h:s, 6j6n:k, 6j6n:s, 6j6q:k, 6j6q:s, 6n7p:K, 6n7x:K, 7oqc:b, 7oqe:b, 8w2o:K, 5zwn:a
23 3m4g:F 71 29 0.1486 0.1549 0.3793 0.27 8bvh:w, 8bvh:x, 8bvh:D, 8bvh:E, 8bvh:F, 8bvh:R, 8bvh:T, 8bvh:J, 8bvh:L, 8bvh:N, 8bvh:P, 8bvh:S, 8bvh:U, 8bvh:K, 8bvh:M, 8bvh:O, 8bvh:Q, 8bvj:R, 8bvj:L, 8bvj:N, 8bvj:P, 8bvj:X, 8bvj:Y, 8bvj:S, 8bvj:U, 8bvj:W, 8bvj:K, 8bvj:M, 8bvj:D, 8bvj:F, 8bvj:I, 8bvm:B, 8bvm:C, 8bvm:D, 8bvm:E, 8bvm:F, 8bvm:G, 8bvm:I, 8bvm:J, 8bvm:K, 8bvm:L, 8bvm:O, 3gib:A, 3gib:B, 3gib:C, 4ht8:A, 4ht8:B, 4ht8:E, 4ht8:F, 4ht8:C, 4ht8:D, 4ht9:A, 4ht9:B, 4ht9:C, 4j5y:A, 4j5y:F, 4j5y:B, 4j5y:C, 4j5y:D, 4j5y:E, 4j6w:A, 4j6w:E, 4j6w:B, 4j6w:C, 4j6w:F, 4j6w:D, 4j6x:A, 4j6x:B, 4j6x:C, 4j6x:D, 4j6x:E, 4j6x:F, 3m4g:A, 3m4g:C, 3m4g:E, 3m4g:G, 3m4g:I, 3m4g:K, 3m4g:L, 4mmk:A, 4mmk:E, 4mmk:K, 4mml:A, 5new:A, 5new:B, 6o1k:I, 6o1k:J, 6o1k:K, 6o1k:L, 6o1k:M, 6o1k:N, 6o1k:C, 6o1k:D, 6o1k:E, 6o1k:F, 6o1k:G, 6o1k:H, 6o1l:I, 6o1l:J, 6o1l:K, 6o1l:L, 6o1l:M, 6o1l:N, 6o1l:C, 6o1l:D, 6o1l:E, 6o1l:F, 6o1l:G, 6o1l:H, 6o1m:I, 6o1m:J, 6o1m:K, 6o1m:L, 6o1m:M, 6o1m:N, 6o1m:C, 6o1m:D, 6o1m:E, 6o1m:F, 6o1m:G, 6o1m:H, 7ogm:K, 7ogm:J, 7ogm:I, 7ogm:E, 7ogm:F, 4pno:A, 3qo3:A, 3qo3:B, 3qo3:C, 3qo3:D, 3qo3:E, 3qui:A, 3qui:F, 3qui:B, 3qui:C, 3qui:D, 3qui:E, 4qvc:D, 4qvd:D, 4qvd:E, 3rer:A, 3rer:B, 3rer:C, 3rer:D, 3rer:E, 3rer:F, 3res:B, 3res:C, 3res:E, 3res:F, 3res:H, 3res:I, 3res:J, 3res:K, 3res:L, 3res:G, 5uk7:C
24 1i5l:C 74 62 0.2297 0.2297 0.2742 0.33 1i5l:E, 1i5l:F, 1i5l:G, 1i5l:J, 1i5l:K, 1i5l:L, 1i5l:A, 1i5l:B, 1i5l:H
25 1lnx:A 74 44 0.1622 0.1622 0.2727 0.34 1lnx:B, 1lnx:C, 1lnx:D, 1lnx:E, 1lnx:F, 1lnx:G
26 6v4x:B 76 43 0.1892 0.1842 0.3256 0.37
27 5vsu:C 81 77 0.2838 0.2593 0.2727 0.43 6aso:C, 4c8q:C, 5gan:3, 4m7a:J, 4m7a:C, 4m7d:J, 4m7d:C, 5nrl:3
28 8ro0:c 80 67 0.2568 0.2375 0.2836 0.45 8ro1:c
29 7pkt:v 120 45 0.1622 0.1000 0.2667 0.54
30 7xde:A 562 41 0.1622 0.0214 0.2927 1.6 7bsj:A, 7bsj:B, 7bsk:A, 7bsk:B, 7bsl:A, 7bsl:B, 1do8:A, 1do8:D, 1do8:B, 1do8:C, 1efk:A, 1efk:D, 1efk:B, 1efk:C, 1efl:A, 1efl:B, 1efl:C, 1efl:D, 1gz3:A, 1gz3:B, 1gz3:C, 1gz3:D, 1gz4:A, 1gz4:B, 1gz4:C, 1gz4:D, 1pj2:A, 1pj2:D, 1pj2:B, 1pj2:C, 1pj3:A, 1pj3:B, 1pj3:C, 1pj3:D, 1pj4:A, 1pj4:B, 1pj4:C, 1pj4:D, 1pjl:A, 1pjl:B, 1pjl:C, 1pjl:D, 1pjl:E, 1pjl:F, 1pjl:G, 1pjl:H, 1qr6:A, 1qr6:B, 7xde:B, 7xde:C, 7xde:D, 7xdf:A, 7xdf:B, 7xdf:C, 7xdf:D, 7xdg:A, 7xdg:B, 7xdg:C, 7xdg:D
31 6tfl:A 62 38 0.1486 0.1774 0.2895 2.0 6tfl:B, 6tfl:C, 6tfl:D, 6tfl:E, 6tfl:F, 6tfl:G, 6tfl:H, 6tfl:I, 6tfl:J, 6tfl:K, 6tfl:L, 6tfl:M, 6tfl:N
32 9fmd:b 87 42 0.2027 0.1724 0.3571 2.1 7a5p:m, 7a5p:b, 7abg:f, 7abi:f, 6ah0:U, 8ch6:n, 5o9z:f, 6qdv:b, 7qtt:n, 4wzj:I, 4wzj:P, 4wzj:BB, 4wzj:II, 4wzj:PP, 4wzj:BBB, 4wzj:III, 4wzj:PPP, 4wzj:BBBB, 4wzj:IIII, 4wzj:PPPP
33 6r7x:A 629 40 0.1757 0.0207 0.3250 2.8 5oc9:A, 5oc9:B, 6r65:A, 6r65:B, 6r7x:B, 6r7y:A, 6r7y:B
34 5vit:A 548 24 0.1081 0.0146 0.3333 2.8 5vit:P, 5vit:I, 5vit:V
35 8aw3:2 177 37 0.1757 0.0734 0.3514 3.9
36 3b2d:A 601 26 0.1622 0.0200 0.4615 3.9 3b2d:B
37 1amp:A 291 41 0.1892 0.0481 0.3415 5.1 2anp:A, 3b35:A, 3b3c:A, 3b3s:A, 3b3t:A, 3b3v:A, 3b3w:A, 3b7i:A, 1cp6:A, 2dea:A, 3fh4:A, 1ft7:A, 1igb:A, 2iq6:A, 1lok:A, 2nyq:A, 2prq:A, 1rtq:A, 1txr:A, 3vh9:A, 1xry:A
38 3two:B 348 21 0.1351 0.0287 0.4762 5.2 3two:A
39 8pvr:B 509 17 0.1351 0.0196 0.5882 5.4 8pvr:A
40 5ys0:B 164 33 0.2027 0.0915 0.4545 5.7 5ys0:A
41 5u04:A 478 31 0.1351 0.0209 0.3226 5.9
42 6ppn:C 75 52 0.1757 0.1733 0.2500 6.2 6ppn:K, 6ppp:C, 6ppp:K, 6ppq:C, 6ppv:C
43 5w5i:C 436 36 0.1351 0.0229 0.2778 7.6 5w5i:A
44 5udk:A 461 26 0.1216 0.0195 0.3462 8.1 6c6k:A, 6c6k:B, 5udi:A, 5udj:A, 5udl:A, 5w5h:A, 5w5h:C
45 1us2:A 507 37 0.2162 0.0316 0.4324 8.9 1gny:A
46 4z9d:C 175 52 0.2297 0.0971 0.3269 9.0 4z9d:A, 4z9d:B, 4z9d:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218