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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MTPTIELICGHRSIRHFTDEPISEAQREAIINSARATSSSSFLQCSSIIRITDKALREELVTLTGGQKHVAQAAEFWVFC
ADFNRHLQICPDAQLGLAEQLLLGVVDTAMMAQNALIAAESLGLGGVYIGGLRNNIEAVTKLLKLPQHVLPLFGLCLGWP
ADNPDLKPRLPASILVHENSYQPLDKGALAQYDEQLAEYYLTRNRRDTWSDHIRRTIIKESRPFILDYLHKQGWATR

The query sequence (length=237) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8ajx:A 240 240 1.0000 0.9875 0.9875 1.23e-177 1f5v:A, 1f5v:B, 7nb9:A, 7niy:A, 7nmp:A, 7nnx:A, 7q0o:A, 7z0w:A, 7z0w:B, 7z0w:C, 7z0w:D, 7z0w:E, 7z0w:F, 7z0w:G, 7z0w:H
2 5uu6:C 236 237 0.5148 0.5169 0.5148 6.63e-86 5uu6:A, 5uu6:B, 5uu6:D
3 1bkj:A 230 234 0.5063 0.5217 0.5128 1.48e-81 1bkj:B, 2bkj:A, 2bkj:B
4 5hdj:B 248 246 0.4599 0.4395 0.4431 3.40e-72 5hdj:A
5 3n2s:A 248 243 0.4135 0.3952 0.4033 5.78e-62 3n2s:B, 3n2s:C, 3n2s:D
6 1zch:A 249 245 0.3966 0.3775 0.3837 8.58e-48
7 5hei:A 246 243 0.4051 0.3902 0.3951 1.31e-44 5hei:B, 5hei:C, 5hei:D, 5hei:E, 5hei:F, 5hei:G, 5hei:H
8 3eof:A 248 247 0.2827 0.2702 0.2713 6.39e-21 3eof:B
9 4dn2:A 191 194 0.2194 0.2723 0.2680 5.59e-15 4dn2:B
10 3m5k:A 168 159 0.1941 0.2738 0.2893 3.47e-13 3m5k:B
11 3kwk:A 168 180 0.1688 0.2381 0.2222 3.65e-10
12 4g8s:A 182 179 0.1899 0.2473 0.2514 1.08e-09 4g8s:B
13 3ge5:A 176 158 0.1519 0.2045 0.2278 1.19e-05 3ge5:B
14 3of4:A 208 68 0.1055 0.1202 0.3676 4.55e-04 3of4:B, 3of4:C
15 3koq:A 173 180 0.1561 0.2139 0.2056 7.09e-04 3h4o:A, 3koq:B, 3koq:C, 3koq:D
16 1nox:A 200 74 0.0970 0.1150 0.3108 0.001
17 8cqt:B 164 178 0.1688 0.2439 0.2247 0.002 8cqt:A
18 3gfa:A 197 191 0.1857 0.2234 0.2304 0.009 3gfa:B
19 3gr3:A 226 214 0.2236 0.2345 0.2477 0.069 3gr3:B
20 3e39:A 175 184 0.1899 0.2571 0.2446 0.071 3e39:B
21 2isj:A 219 201 0.1941 0.2100 0.2289 0.097 2isj:B, 2isj:C, 2isj:D, 2isj:E, 2isj:F, 2isj:G, 2isj:H, 2isk:A, 2isk:B, 2isk:C, 2isk:D, 2isk:E, 2isk:F, 2isk:G, 2isk:H, 2isl:A, 2isl:B, 2isl:C, 2isl:D, 2isl:E, 2isl:F, 2isl:G, 2isl:H
22 8ep6:A 245 54 0.0675 0.0653 0.2963 0.15
23 6a7w:A 324 129 0.1266 0.0926 0.2326 0.52 6a7w:B, 5mx9:A, 6sut:A
24 4xoq:A 204 87 0.1224 0.1422 0.3333 0.93 4xoo:A, 4xoo:B, 4xoo:C, 4xoo:D, 4xoq:B, 4xoq:C, 4xoq:D
25 7jh4:A 223 90 0.1097 0.1166 0.2889 1.2 7jh4:B, 7jh4:C, 7jh4:D, 7jh4:E
26 2wtk:B 311 145 0.1392 0.1061 0.2276 1.9 3gni:B, 8vsu:B, 2wtk:E
27 7ry3:C 1048 171 0.1688 0.0382 0.2339 4.6 7m4p:B
28 4g9b:A 227 60 0.0886 0.0925 0.3500 5.9
29 7blz:B 731 43 0.0759 0.0246 0.4186 6.4 6fos:B, 8wey:B, 5zgb:B, 5zgh:B
30 7ckf:A 256 128 0.1392 0.1289 0.2578 7.7 7ckf:B
31 8c4t:A 1268 70 0.0717 0.0134 0.2429 9.7
32 7dp0:A 223 39 0.0591 0.0628 0.3590 9.7 7dp0:B, 7dp1:A, 7dp1:B, 7dp2:A, 7dp2:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218