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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MTIATIDIGGTGIKFASLTPDGKILDKTSISTPENLEDLLAWLDQRLSEQDYSGIAMSVPGAVNQETGVIDGFSAVPYIH
GFSWYEALSSYQLPVHLENDANCVGLSELLAHPELENAACVVIGTGIGGAMIINGRLHRGRHGLGGEFGYMTTLAPAEKL
NNWSQLASTGNMVRYVIEKSGHTDWDGRKIYQEAAAGNILCQEAIERMNRNLAQGLLNIQYLIDPGVISLGGSISQNPDF
IQGVKKAVEDFVDAYEEYTVAPVIQACTYHADANLYGALVNWLQEEKQW

The query sequence (length=289) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 2gup:A 289 289 1.0000 1.0000 1.0000 0.0
2 7p7w:BBB 306 257 0.2491 0.2353 0.2802 1.47e-17 7p7i:AAA, 7p7i:BBB, 7p7w:AAA, 7p9l:AAA, 7p9l:BBB, 7p9p:AAA, 7p9p:BBB, 7p9y:AAA, 7p9y:BBB, 7pa1:AAA, 7pa1:BBB
3 4db3:A 311 278 0.2595 0.2412 0.2698 9.00e-15
4 2qm1:B 325 320 0.2872 0.2554 0.2594 1.89e-13 2qm1:A, 2qm1:C, 2qm1:D
5 3vgk:B 312 263 0.2318 0.2147 0.2548 1.63e-11 3vgk:A, 3vgk:C, 3vgk:D, 3vgk:E, 3vgk:F, 3vgk:G, 3vgk:H, 3vgl:A, 3vgm:A
6 6jdc:A 269 297 0.2561 0.2751 0.2492 6.41e-10
7 1z05:A 396 244 0.2249 0.1641 0.2664 1.91e-09
8 5f7q:E 396 268 0.2076 0.1515 0.2239 3.40e-09 5f7p:E, 5f7p:A, 5f7q:C, 5f7q:J, 5f7q:L, 5f7r:E, 5f7r:A
9 6jdb:A 290 301 0.2284 0.2276 0.2193 4.29e-09
10 3vov:B 298 305 0.2976 0.2886 0.2820 4.97e-07 3vov:A, 3vov:C, 3vov:D
11 6jdh:A 293 161 0.1557 0.1536 0.2795 1.64e-05 6jda:A, 6jdh:B, 6jdo:A, 6jdo:B
12 1xc3:A 295 144 0.1453 0.1424 0.2917 1.22e-04 3lm9:A, 3ohr:A
13 1z6r:A 382 238 0.1799 0.1361 0.2185 4.93e-04 3bp8:A, 3bp8:B, 1z6r:B, 1z6r:C, 1z6r:D
14 2aa4:A 289 253 0.2353 0.2353 0.2688 0.001 2aa4:B
15 2yhw:A 309 278 0.2111 0.1974 0.2194 0.008 2yhy:A, 2yi1:A
16 2ap1:A 305 257 0.2215 0.2098 0.2490 0.066
17 1woq:A 253 57 0.0761 0.0870 0.3860 0.89 1woq:B
18 8vbu:A 505 67 0.0623 0.0356 0.2687 1.8 7o4a:BBB, 7o4b:A, 7o4b:C, 8vbu:B, 8vbv:A, 8vbv:B, 8vbw:A, 8vbw:B
19 7ok9:B 525 67 0.0623 0.0343 0.2687 2.0 7o4a:AAA, 7ok9:A, 7ok9:E, 7ok9:C, 7ok9:G, 7ok9:H, 7ok9:I, 7ok9:D, 7ok9:F, 7ok9:J
20 3eo3:A 288 270 0.2111 0.2118 0.2259 2.6 3eo3:B, 3eo3:C
21 7t8s:B 78 38 0.0484 0.1795 0.3684 2.8 7t8s:F, 7t8s:J, 7t8s:N
22 6s1m:A 1010 42 0.0623 0.0178 0.4286 3.5 6s1n:A, 6s1o:A, 6tny:A, 6tnz:A
23 5dpd:A 511 52 0.0554 0.0313 0.3077 3.7 5dnk:A, 5dnk:B, 5dpd:B
24 6vdc:A 497 60 0.0554 0.0322 0.2667 4.1
25 2wc1:A 182 62 0.0554 0.0879 0.2581 6.4
26 8gxf:B 187 93 0.0761 0.1176 0.2366 6.7 8gxf:A, 8gxf:C, 8gxf:D
27 8rbx:b 1051 41 0.0450 0.0124 0.3171 7.1 7pks:b, 8rbz:b
28 6vdd:A 567 39 0.0415 0.0212 0.3077 8.7 6vdd:D
29 4yed:D 255 34 0.0346 0.0392 0.2941 8.8 4d79:A, 4d79:B, 4d79:C, 4d79:D, 4d7a:A, 4d7a:B, 4d7a:D, 4rdh:A, 4rdh:B, 4rdh:C, 4rdh:D, 4rdi:A, 4rdi:B, 4rdi:C, 4rdi:D, 4yed:A, 4yed:B, 4yed:C
30 6vde:A 860 39 0.0415 0.0140 0.3077 9.6 6vde:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218