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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MSLVNRKQLEKMANVRFRVQEDEYVAILDALEEYHNMSENTVVEKYLKLKDINSLTDTYIDTYKKSGRNKALKKFKEYLV
IEILELKNSNLTPVEKNLHFIWIGGQINDTAINYINQWKDVNSDYNVNVFYDSNAFLINTLKKTIIESASNDTLESFREN
LNDPEFNHTAFFRKRMQIIYDKQQNFINYYKAQKEENPDLIIDDIVKTYLSNEYSKDIDELNAYIEESLNKVTENSGNDV
RNFEEFKTGEVFNLYEQELVERWNLAGASDILRVAILKNIGGVYLDVDMLPGIHPDLFKDINKPDSVKTAVDWEEMQLEA
IMKHKEYIPEYTSKHFDTLDEEVQSSFESVLASKSDKSEIFLPLGDIEVSPLEVKIAFAKGSIINQALISAKDSYCSDLL
IKQIQNRYKILNDTLGPIISQGNDFNTTMNNFGESLGAIANEENISFIAKIGSYLRVGFYPEANTTITLSGPTIYAGAYK
DLLTFKEMSIDTSILSSELRNFEFPKVNISQATEQEKNSLWQFNEERAKIQFEEYKKNYFE

The query sequence (length=541) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8y9c:B 1609 541 0.9945 0.3344 0.9945 0.0
2 6oq5:A 2346 540 0.9982 0.2302 1.0000 0.0 6oq7:A, 7s0z:B, 7s0z:A
3 8y9b:B 1607 540 0.7893 0.2657 0.7907 0.0
4 8qeo:A 2146 540 0.7893 0.1990 0.7907 0.0
5 8qen:A 2363 540 0.7893 0.1807 0.7907 0.0 9bja:A, 9bja:B, 2bvl:A, 2bvm:A, 6c0b:A, 7lou:A, 7lou:B, 7lov:A, 7lov:B, 3pa8:A, 3pa8:B, 3pee:B, 3pee:A, 7s0y:A, 5uqm:A, 5uqn:A, 5uqt:A, 5uqt:B
6 7ml7:A 1216 541 0.7856 0.3495 0.7856 0.0
7 8x2i:A 2303 541 0.7394 0.1737 0.7394 0.0
8 8x2h:A 2363 541 0.7394 0.1693 0.7394 0.0 8jb5:A, 2vkd:A, 2vkd:B, 2vkd:C, 2vkh:A, 2vkh:B, 2vkh:C, 2vl8:A, 2vl8:B, 2vl8:C
9 8jhz:A 2615 539 0.5046 0.1044 0.5065 9.08e-174
10 7pog:A 2382 539 0.4898 0.1113 0.4917 6.89e-168 4dmw:A, 3ho6:A, 3ho6:B, 4r04:A, 3srz:A, 3ss1:A, 7u2p:A, 7uby:B, 7uby:A, 5uqk:A, 5uql:A
11 6rtg:A 503 411 0.1941 0.2087 0.2555 7.93e-17
12 4mix:B 277 135 0.0739 0.1444 0.2963 0.002 4mix:A
13 4mix:B 277 46 0.0388 0.0758 0.4565 0.006 4mix:A
14 8ovs:AAA 276 53 0.0407 0.0797 0.4151 0.003 8ovs:BBB
15 8ovs:AAA 276 43 0.0314 0.0616 0.3953 0.083 8ovs:BBB
16 5w6q:A 515 49 0.0314 0.0330 0.3469 0.86
17 4n56:A 494 49 0.0314 0.0344 0.3469 1.0
18 1taq:A 807 49 0.0314 0.0211 0.3469 1.6 4bwj:A, 4bwm:A, 4c8k:A, 4c8l:A, 4c8m:A, 4c8n:A, 4c8o:A, 4cch:A, 4df4:A, 4df8:A, 4dfj:A, 4dfk:A, 4dfm:A, 4dfp:A, 4dle:A, 4dlg:A, 5e41:A, 4elt:A, 4elu:A, 4elv:A, 6fbc:A, 6fbd:A, 6fbe:A, 6fbf:A, 6fbg:A, 6fbh:A, 6fbi:A, 2ktq:A, 3ktq:A, 4ktq:A, 5ktq:A, 3lwl:A, 3lwm:A, 3m8r:A, 3m8s:A, 4n5s:A, 5nkl:A, 5o7t:A, 3ojs:A, 3oju:A, 7owf:A, 5oxj:A, 3po4:A, 3po5:A, 3py8:A, 6q4u:A, 6q4v:A, 1qss:A, 1qsy:A, 1qtm:A, 3rr7:A, 3rr8:A, 3rrg:A, 3rrh:A, 3rtv:A, 3sv3:A, 3sv4:A, 3syz:A, 3sz2:A, 5szt:A, 3t3f:A, 1tau:A, 5w6k:A, 5w6q:C, 5w6q:G, 4xiu:A, 5ytc:A, 5ytd:A, 5yte:A, 5ytf:A, 5ytg:A, 5yth:A, 5z3n:A
19 1fa2:A 498 134 0.0573 0.0622 0.2313 2.6 5wqu:A
20 1ffy:A 917 76 0.0425 0.0251 0.3026 7.4 1qu2:A, 1qu3:A
21 8sft:B 428 36 0.0314 0.0397 0.4722 7.4 8gkn:A, 8gkn:B, 8sft:A, 8sft:C, 8sft:D, 8sfu:A, 8sfu:B, 8sfw:A, 8sfy:A
22 7pnt:L 176 43 0.0296 0.0909 0.3721 9.9 7pnu:L, 7pnv:L, 7pnw:L

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218