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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MSLADFMEQRVQVITNDGRVVLGSLKGFDHTTNLILSDSFERIISMDQDMETIPLGVYLLRGENVAMVGLVNEELDSEIE
WTKIRGEAIPDVVH

The query sequence (length=94) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6ppn:H 94 94 1.0000 1.0000 1.0000 4.86e-65 6ppn:P, 6ppp:H, 6ppp:P
2 6qw6:68 95 93 0.4574 0.4526 0.4624 3.40e-27 6ahd:z, 8h6e:6g, 8h6j:6g, 8h6k:6g, 8h6l:6g, 6qx9:68, 8qxd:68, 8r08:68, 8r09:68, 8r0a:68, 8r0b:68, 8rm5:68
3 6ppq:A 69 68 0.2979 0.4058 0.4118 1.24e-11 6ppv:A
4 5vsu:H 100 71 0.2660 0.2500 0.3521 5.67e-10 5gan:8, 4m7a:H, 4m7a:A, 4m7d:H, 4m7d:A, 5nrl:8, 5zwo:z
5 6aso:H 83 84 0.2766 0.3133 0.3095 3.68e-09
6 6bk8:f 80 63 0.2447 0.2875 0.3651 6.37e-08 6bk8:k, 7dco:a, 7dco:h, 6exn:k, 6exn:b, 6g90:s, 5gam:b, 5gan:k, 5gan:b, 5gao:k, 5gm6:k, 5gmk:k, 5gmk:s, 3jcm:S, 5lj3:b, 5lj5:b, 5mps:b, 5mq0:k, 5mq0:b, 5nrl:s, 5nrl:k, 5nrl:b, 7oqb:s, 7oqe:s, 5wsg:k, 5wsg:F, 5y88:a, 5y88:h, 5ylz:a, 5ylz:h, 5zwm:P, 5zwm:a, 5zwm:h, 5zwo:a, 5zwo:P
7 9fmd:b 87 59 0.2447 0.2644 0.3898 1.83e-07 7a5p:m, 7a5p:b, 7abg:f, 7abi:f, 6ah0:U, 8ch6:n, 5o9z:f, 6qdv:b, 7qtt:n, 4wzj:I, 4wzj:P, 4wzj:BB, 4wzj:II, 4wzj:PP, 4wzj:BBB, 4wzj:III, 4wzj:PPP, 4wzj:BBBB, 4wzj:IIII, 4wzj:PPPP
8 6v4x:B 76 59 0.2553 0.3158 0.4068 2.04e-07
9 7w59:b 102 65 0.2660 0.2451 0.3846 3.83e-07 7abg:m, 7abi:m, 6ahd:a, 7b0y:j, 8c6j:b, 8ch6:8, 7dvq:i, 9fmd:i, 8h6e:5a, 8h6e:4a, 8h6j:5a, 8h6j:4a, 8h6k:5a, 8h6l:5a, 8i0p:a, 8i0p:m, 8i0r:a, 8i0r:m, 8i0s:m, 8i0t:a, 8i0t:m, 8i0u:m, 8i0v:a, 8i0v:m, 8i0w:a, 8i0w:i, 6icz:i, 4pjo:B, 4pjo:b, 4pjo:P, 4pjo:p, 8q7q:b, 8q7v:b, 8q7w:b, 8q7x:b, 8q91:h, 6qdv:k, 8qo9:5b, 8qo9:4b, 6qw6:4b, 6qw6:5b, 6qx9:1b, 6qx9:5b, 6qx9:2b, 6qx9:4b, 8qxd:4b, 8qxd:5b, 8qzs:5b, 8qzs:2b, 8r08:1b, 8r08:4b, 8r08:5b, 8r09:5b, 8r0a:5b, 8r0b:5b, 8rc0:h, 8rm5:2b, 8rm5:5b, 8ro2:b, 7vpx:k, 7w59:i, 7w5a:b, 7w5a:i, 7w5b:b, 7w5b:i, 4wzj:B, 5xjc:b, 5xjc:i, 8y6o:a, 8y6o:h, 8y6o:o, 8y7e:i, 5yzg:b, 5yzg:i, 5z56:b, 5z56:i, 5z57:b, 5z57:i, 5z58:b, 5z58:i
10 6n7r:K 124 76 0.2553 0.1935 0.3158 1.02e-06 7b9v:k, 7b9v:b, 6g90:b, 6j6g:k, 6j6g:s, 6j6h:k, 6j6h:s, 6j6n:k, 6j6n:s, 6j6q:k, 6j6q:s, 6n7p:K, 6n7x:K, 7oqc:b, 7oqe:b, 8w2o:K, 5zwn:a
11 3jb9:J 73 66 0.2340 0.3014 0.3333 1.20e-05 3jb9:o
12 6v4x:G 77 66 0.2234 0.2727 0.3182 1.81e-05 7a5p:k, 7a5p:g, 7abg:k, 7abi:k, 6ah0:n, 6ahd:S, 6ahd:f, 6ahd:n, 7b0y:h, 8c6j:r, 8c6j:g, 8ch6:m, 8ch6:9, 7dvq:g, 7dvq:n, 7evo:d, 9fmd:n, 9fmd:g, 8h6e:5f, 8h6e:4f, 8h6e:2f, 8h6j:5f, 8h6j:4f, 8h6j:2f, 8h6k:5f, 8h6k:4f, 8h6k:2f, 8h6l:5f, 8h6l:4f, 8h6l:2f, 8hk1:d, 8i0p:k, 8i0r:k, 8i0s:f, 8i0s:k, 8i0t:k, 8i0u:f, 8i0u:k, 8i0v:k, 8i0w:n, 6icz:g, 6id0:g, 6id1:g, 5mqf:k, 5mqf:d, 5o9z:k, 4pjo:G, 4pjo:g, 4pjo:U, 4pjo:u, 8q7q:g, 8q7v:g, 8q7w:g, 8q7x:g, 8q91:n, 6qdv:r, 6qdv:g, 8qo9:2g, 8qo9:4g, 7qtt:m, 6qw6:4g, 6qw6:5g, 6qx9:1g, 6qx9:5g, 6qx9:2g, 6qx9:4g, 8qxd:2g, 8qxd:4g, 8qxd:5g, 8qzs:5g, 8qzs:2g, 8qzs:4g, 8r08:1g, 8r08:2g, 8r08:4g, 8r08:5g, 8r09:2g, 8r09:5g, 8r09:4g, 8r0a:5g, 8r0a:2g, 8r0a:4g, 8r0b:2g, 8r0b:4g, 8r0b:5g, 8rc0:n, 8rm5:2g, 8rm5:5g, 8rm5:4g, 8ro2:g, 7vpx:d, 7vpx:n, 7w59:g, 7w59:n, 7w5a:g, 7w5a:n, 7w5b:g, 7w5b:n, 4wzj:G, 4wzj:N, 4wzj:U, 4wzj:GG, 4wzj:NN, 4wzj:UU, 4wzj:GGG, 4wzj:NNN, 4wzj:UUU, 4wzj:GGGG, 4wzj:NNNN, 4wzj:UUUU, 5xjc:g, 5xjc:n, 6y53:k, 6y5q:k, 8y6o:g, 8y6o:n, 8y6o:u, 8y7e:n, 5yzg:g, 5yzg:n, 5z56:g, 5z56:n, 5z57:g, 5z57:n, 5z58:g, 5z58:n
13 4m7a:F 66 62 0.2128 0.3030 0.3226 2.27e-05
14 8ro0:b 98 56 0.2128 0.2041 0.3571 4.50e-04 8ro1:b
15 3jb9:E 98 61 0.2340 0.2245 0.3607 0.001 3jb9:b
16 5vsu:C 81 43 0.1383 0.1605 0.3023 0.002 6aso:C, 4c8q:C, 5gan:3, 4m7a:J, 4m7a:C, 4m7d:J, 4m7d:C, 5nrl:3
17 8ro0:n 77 66 0.1915 0.2338 0.2727 0.002 8ro0:g, 8ro1:g
18 1lnx:A 74 70 0.2447 0.3108 0.3286 0.009 1lnx:B, 1lnx:C, 1lnx:D, 1lnx:E, 1lnx:F, 1lnx:G
19 7b9v:p 77 71 0.1915 0.2338 0.2535 0.020 7b9v:e, 6bk8:c, 7dco:i, 6exn:p, 6exn:e, 6g90:e, 6g90:w, 5gan:p, 5gao:p, 5gm6:i, 5gmk:i, 5gmk:u, 6j6g:i, 6j6g:u, 6j6h:i, 6j6h:u, 6j6n:i, 6j6n:u, 6j6q:i, 6j6q:u, 5mps:e, 5mq0:e, 6n7p:O, 6n7r:O, 6n7x:O, 5nrl:w, 5nrl:p, 5nrl:e, 7oqb:w, 7oqc:e, 7oqe:w, 8w2o:O, 5wsg:i, 5wsg:G, 5y88:b, 5y88:i, 5ylz:b, 5ylz:i, 5zwm:T, 5zwm:i, 5zwn:e, 5zwo:T, 5zwo:i
20 3jb9:H 76 46 0.1489 0.1842 0.3043 0.044 3jb9:m
21 8e4f:A 181 73 0.2340 0.1215 0.3014 0.11
22 1loj:C 77 46 0.1809 0.2208 0.3696 0.23 1loj:A, 1loj:B, 1loj:D, 1loj:E, 1loj:F, 1loj:G, 1loj:H, 1loj:I, 1loj:J, 1loj:K, 1loj:L, 1loj:M, 1loj:N
23 7v00:F 695 80 0.2447 0.0331 0.2875 0.37 7v01:F
24 1m8v:A 72 63 0.2128 0.2778 0.3175 0.47 1m8v:M, 1m8v:C, 1m8v:K, 1m8v:F, 1m8v:H, 1m8v:E, 1m8v:I, 1m8v:D, 1m8v:J, 1m8v:B, 1m8v:L, 1m8v:G, 1m8v:N
25 7abg:j 81 46 0.1702 0.1975 0.3478 0.88 7a5p:j, 7a5p:e, 7abi:j, 6ah0:c, 6ahd:e, 7b0y:g, 8c6j:p, 8c6j:e, 8ch6:i, 8ch6:1, 7dvq:e, 7dvq:l, 9fmd:l, 9fmd:e, 8h6e:5e, 8h6e:4e, 8h6j:5e, 8h6j:4e, 8h6k:5e, 8h6l:5e, 8i0p:e, 8i0p:j, 8i0r:e, 8i0r:j, 8i0s:e, 8i0s:j, 8i0t:e, 8i0t:j, 8i0u:e, 8i0u:j, 8i0v:e, 8i0v:j, 8i0w:e, 8i0w:l, 6icz:e, 6id0:e, 6id1:e, 5mqf:j, 5mqf:c, 5o9z:j, 4pjo:E, 4pjo:e, 4pjo:S, 4pjo:s, 8q7q:e, 8q7v:e, 8q7w:e, 8q7x:e, 6qdv:p, 6qdv:e, 8qo9:2e, 8qo9:5e, 8qo9:4e, 7qtt:i, 6qw6:4e, 6qw6:5e, 6qx9:1e, 6qx9:5e, 6qx9:2e, 6qx9:4e, 8qxd:2e, 8qxd:4e, 8qzs:5e, 8qzs:2e, 8qzs:4e, 8r08:1e, 8r08:2e, 8r08:4e, 8r09:2e, 8r09:5e, 8r09:4e, 8r0a:5e, 8r0a:2e, 8r0a:4e, 8r0b:4e, 8r0b:5e, 8rm5:2e, 8rm5:5e, 8rm5:4e, 8ro2:e, 6v4x:E, 7vpx:l, 7w59:e, 7w59:l, 7w5a:e, 7w5a:l, 7w5b:e, 7w5b:l, 4wzj:E, 4wzj:L, 4wzj:S, 4wzj:EE, 4wzj:LL, 4wzj:SS, 4wzj:EEE, 4wzj:LLL, 4wzj:SSS, 4wzj:EEEE, 4wzj:LLLL, 4wzj:SSSS, 5xjc:e, 5xjc:l, 8y6o:e, 8y6o:l, 8y6o:s, 8y7e:l, 5yzg:e, 5yzg:l, 5z56:e, 5z56:l, 5z57:e, 5z57:l, 5z58:e, 5z58:l
26 4ilo:A 236 58 0.1383 0.0551 0.2241 1.5 4ilo:B
27 6p24:B 793 42 0.1383 0.0164 0.3095 2.8
28 5f75:C 475 23 0.1064 0.0211 0.4348 4.9 8bpn:A, 8bpn:B, 8bpn:C, 8bpn:D, 5f75:A, 5f75:B, 5f75:D, 6g50:A, 6g50:B, 6g50:C, 6g50:D, 6g5m:A, 6g5m:B, 6g5m:C, 6g5m:D, 6i3q:A, 6i3q:B, 6i3q:C, 6i3q:D, 5oex:A, 5oex:B, 5oex:C, 5oex:D, 8p3l:A, 8p3l:D, 8p3l:G, 8p3l:J, 8p3m:A, 8p3m:D, 8p3m:G, 8p3m:J, 8p3m:M, 8p3m:P, 8p3m:S, 8p3m:V, 8p3m:Y, 8p3m:2, 8p3m:5, 8p3m:8, 8p3m:x, 8p3m:e, 8p3m:h, 8p3m:k, 6sji:A, 6sji:B, 6sji:J, 6sji:K, 6uwe:A, 6uwe:B, 6uwe:C, 6uwe:D
29 3rgq:A 156 64 0.2128 0.1282 0.3125 5.3
30 6c9x:A 666 37 0.1064 0.0150 0.2703 7.4 6c9x:B, 6c9z:A, 6c9z:B, 6ca1:A, 6ca1:B, 6ca3:A, 6ca3:B, 3mkk:B, 3mkk:A, 3pha:A, 3pha:B, 3pha:C, 3pha:D, 3poc:B, 3poc:A
31 8y6o:q 104 38 0.1170 0.1058 0.2895 9.5 7a5p:h, 7abg:a, 7abi:a, 6ah0:k, 6ah0:P, 6ahd:P, 6ahd:k, 8ch6:l, 8ch6:4, 7dvq:k, 8h6e:2c, 8h6j:2c, 8h6k:4c, 8h6k:2c, 8h6l:4c, 8h6l:2c, 8i0w:k, 6id0:k, 6id1:k, 5o9z:h, 5o9z:a, 4pjo:R, 7qtt:l, 8qzs:42, 7w59:k, 7w5a:k, 7w5b:k, 5xjc:k, 8y7e:k, 5yzg:k, 5z56:k, 5z57:k, 5z58:k
32 1i5l:C 74 63 0.2128 0.2703 0.3175 9.9 1i5l:E, 1i5l:F, 1i5l:G, 1i5l:J, 1i5l:K, 1i5l:L, 1i5l:A, 1i5l:B, 1i5l:H

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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