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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MSKVKSITRESWILSTFPEWGSWLNEEIEQEQVAPGTFAMWWLGCTGIWLKSEGGTNVCVDFWCGTGKQSHGLQPNLRTT
PFVLDPFAIRQIDAVLATHDHNDHIDVNVAAAVMQNCADDVPFIGPKTCVDLWIGWGVPKERCIVVKPGDVVKVKDIEIH
ALDAFDGMDDRAVNYLFKTPGGSLYHSGDSHYSNYYAKHGNEHQIDVALGSYGENPRGITDKMTSADMLRMGEALNAKVV
IPFHHDIWSNFQADPQEIRVLWEMKKDRLKYGFKPFIWQVGGKFTWPLDKDNFEYHYPRG

The query sequence (length=300) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 2wym:A 303 301 0.9967 0.9868 0.9934 0.0 2wym:B, 2wym:C, 2wym:D, 2wym:E, 2wym:F
2 3bv6:B 354 337 0.7267 0.6158 0.6469 1.55e-164 3bv6:A, 3bv6:C, 3bv6:D, 3bv6:E, 3bv6:F
3 7e3w:B 239 85 0.0733 0.0921 0.2588 0.001 7e3v:A, 7e3v:B, 7e3v:C, 7e3v:D, 7e3v:E, 7e3v:F, 7e3w:A, 7e3w:C, 7e3w:D, 7e3w:E, 7e3w:F
4 8p90:B 334 104 0.0767 0.0689 0.2212 0.039 8p90:A, 8p96:A, 8p96:B, 8pc4:A, 8pc4:B, 4qn9:A, 4qn9:B
5 6hrg:A 233 232 0.1667 0.2146 0.2155 0.44
6 7khs:C 427 75 0.0667 0.0468 0.2667 0.57
7 7khs:A 449 75 0.0667 0.0445 0.2667 0.60 7khs:B, 7khs:D, 2xsb:A
8 2xr1:B 611 65 0.0700 0.0344 0.3231 0.61 2xr1:A
9 7y7u:A 288 59 0.0700 0.0729 0.3559 1.3 7y7u:B
10 1fsj:B 134 69 0.0700 0.1567 0.3043 4.1 1fr2:B, 1fsj:C, 1fsj:D, 1fsj:E, 2gyk:B, 2gyk:F, 2gze:B, 2gzf:B, 2gzg:B, 2gzi:B, 2gzj:B, 2gzj:F, 1v13:A, 1v13:B, 1v14:A, 1v14:B, 1v14:C, 1v14:D, 1v15:B, 1v15:D, 1v15:C
11 7u2r:A 244 29 0.0433 0.0533 0.4483 4.5
12 1o7a:A 483 66 0.0600 0.0373 0.2727 4.6 2gk1:N, 2gk1:O, 2gk1:P, 2gk1:R, 2gk1:T, 3lmy:A, 3lmy:B, 1now:A, 1now:B, 1np0:D, 1np0:E, 1np0:F, 1o7a:B, 1o7a:C, 1o7a:D, 1o7a:E, 1o7a:F
13 5jft:A 238 45 0.0533 0.0672 0.3556 5.2 5jft:B, 7jl7:A, 7jl7:C
14 3a4y:A 431 52 0.0600 0.0418 0.3462 5.8 3a4y:B, 3a4y:C, 3a4y:D, 2dkf:A, 2dkf:B, 2dkf:C, 2dkf:D, 3idz:A, 3idz:B, 3idz:C, 3idz:D, 3ie0:A, 3ie0:B, 3ie0:C, 3ie0:D, 3ie1:A, 3ie1:B, 3ie1:C, 3ie1:D, 3ie2:A, 3ie2:B, 3ie2:C, 3ie2:D, 3iek:A, 3iek:B, 3iek:C, 3iek:D, 3iel:A, 3iel:B, 3iel:C, 3iel:D, 3iem:A, 3iem:B, 3iem:D, 3iem:C
15 5a0t:A 454 102 0.0867 0.0573 0.2549 6.7 5a0t:B, 5a0v:A, 5a0v:B
16 2ze3:A 275 51 0.0567 0.0618 0.3333 7.7
17 4xhc:A 513 28 0.0433 0.0253 0.4643 7.9 4xhc:B
18 8jjm:A 484 70 0.0633 0.0393 0.2714 8.6 8jjm:B
19 2bib:A 540 22 0.0300 0.0167 0.4091 9.0 1wra:A, 1wra:B
20 4bwr:A 467 41 0.0367 0.0236 0.2683 10.0

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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