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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MRKENCLFSGLPVHPGHGKRFVPTLVQSTRPVLTFVTAKTRKLYLRKKNPRVIRWTVTYRKLNKKT

The query sequence (length=66) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6zj3:Lm 66 66 1.0000 1.0000 1.0000 2.05e-43
2 4v8m:BY 100 66 0.5606 0.3700 0.5606 3.47e-22 8ova:BY, 8ove:BY, 5t5h:Y
3 8rxh:LX 85 65 0.5455 0.4235 0.5538 1.04e-20 8a3w:X, 8a98:X, 6az3:X, 3jcs:X, 8ovj:X, 8rxx:LX, 5t2a:W
4 9bh5:CW 88 65 0.4697 0.3523 0.4769 4.17e-14 9cai:CW
5 7ls2:Q2 110 65 0.4394 0.2636 0.4462 1.10e-13 8bhf:J1, 6d90:W, 6d9j:W, 6hcf:W3, 6hcm:W3, 5lzs:W, 5lzt:W, 5lzu:W, 5lzv:W, 5lzw:W, 5lzx:W, 5lzy:W, 5lzz:W, 6mtb:W, 6mtc:W, 6mtd:W, 6mte:W, 7nwh:W, 6r5q:W, 6r6g:W, 6r7q:W, 6sgc:W2, 7ucj:W, 7uck:W, 7zjw:LZ, 7zjx:LZ
6 8ifd:2Q 124 65 0.4394 0.2339 0.4462 1.40e-13 7a01:l2, 8a3d:Q, 5aj0:AW, 8b5l:W, 8b6c:W, 9bdl:AL24, 9bdn:AL24, 9bdp:AL24, 8bpo:V2, 8btk:BW, 7cpu:LW, 7cpv:LW, 4d5y:W, 4d67:W, 9f1b:BW, 9f1c:BW, 9f1d:BW, 7f5s:LW, 6frk:W, 6ftg:W, 6fti:W, 6ftj:W, 8g5y:LW, 8g5z:LW, 8g60:LW, 8g61:LW, 8g6j:LW, 8glp:LW, 6gz3:AW, 6gz4:AW, 6gz5:AW, 8ife:2Q, 6ip5:2Q, 6ip6:2Q, 6ip8:2Q, 3j7o:W, 3j7p:W, 3j7q:W, 3j7r:W, 3j92:W, 3jag:W, 3jah:W, 3jai:W, 3jaj:W, 3jan:W, 8jdj:b, 8jdk:b, 8jdl:b, 8jdm:b, 8k2c:LW, 5lks:LW, 6lqm:f, 6lsr:f, 7ls1:Q2, 7mdz:W, 7nfx:W, 7nwg:W, 7nwi:W, 7o7y:BW, 7o7z:BW, 7o80:BW, 7o81:BW, 7obr:W, 8ohd:LW, 8oj0:LW, 8oj5:LW, 8oj8:LW, 6ole:X, 6olf:X, 6olg:AW, 6oli:X, 6olz:AW, 6om0:X, 6om7:X, 7ow7:u, 7oya:W1, 7oyb:W1, 7oyc:W1, 7oyd:W, 8p2k:BW, 6p5i:AW, 6p5j:AW, 6p5k:AW, 6p5n:AW, 8q7z:BW, 8q87:BW, 8qfd:W, 7qgg:X, 8qoi:LW, 7qvp:LW, 7qvp:MW, 7qwq:W, 7qwr:W, 7qws:W, 6qzp:LW, 6r6p:W, 8rjb:W, 8rjc:W, 8rjd:W, 8scb:W, 6swa:U, 5t2c:Q, 6t59:W3, 7tm3:W, 7toq:AL24, 7tor:AL24, 7tut:W, 4ug0:LW, 4ujc:BW, 4ujd:AW, 4uje:CW, 4v6x:CW, 6w6l:X, 6xa1:LW, 7xnx:LW, 7xny:LW, 8xsx:LW, 8xsy:LW, 8xsz:LW, 6y0g:LW, 8y0w:LW, 8y0x:LW, 6y2l:LW, 6y57:LW, 6y6x:LW, 8yoo:LW, 8yop:LW, 6z6l:LW, 6z6m:LW, 6z6n:LW, 6zm7:LW, 6zme:LW, 6zmi:LW, 6zmo:LW, 6zvk:l2
7 4v6w:CW 130 60 0.3939 0.2000 0.4333 1.86e-11 6xu6:CW, 6xu7:CW, 6xu8:CW
8 8fl2:SV 139 61 0.3788 0.1799 0.4098 2.90e-10 8fkp:SV, 8fkq:SV, 8fkr:SV, 8fks:SV, 8fkt:SV, 8fku:SV, 8fkv:SV, 8fkw:SV, 8fkx:SV, 8fky:SV, 8fkz:SV, 8fl0:SV, 8fl3:SV, 8fl4:SV, 8fl6:SV, 8fl7:SV, 8fl9:SV, 8fla:SV, 8flb:SV, 8flc:SV, 8fld:SV, 8fle:SV, 8flf:SV, 8idt:7, 8idy:7, 8ie3:7, 8ine:7, 8inf:7, 8ink:7, 8ipd:7, 8ipx:7, 8ipy:7, 8ir1:7, 8ir3:7, 6lss:7, 6lu8:7
9 5an9:G 69 66 0.3485 0.3333 0.3485 6.42e-10 5anb:G, 5anc:G, 6qkl:G
10 5xy3:W 59 62 0.3485 0.3898 0.3710 1.40e-09
11 8br8:LX 63 65 0.4091 0.4286 0.4154 1.45e-09 8brm:LX, 8bsi:LX, 8bsj:LX, 8btd:LX, 8btr:LX
12 7olc:LW 133 65 0.3788 0.1880 0.3846 2.06e-09 7old:LW, 8oo0:LW, 7r81:Y1, 7z3n:LW, 7z3o:LW
13 8esr:u 101 65 0.3939 0.2574 0.4000 4.68e-09
14 8esq:u 114 65 0.3939 0.2281 0.4000 4.77e-09 8etc:u, 8eth:u, 8eti:u, 8etj:u, 8eug:u, 8eui:u
15 8c3a:7 118 65 0.3788 0.2119 0.3846 8.60e-09 8c3a:BR, 8cq7:7, 8cq7:BR, 8cqw:7, 8cqw:BR, 8cre:7, 8cre:BR, 8oeq:7, 8oeq:BR, 7pzy:7, 7q08:7, 7q0f:7, 7q0p:7, 7q0r:7, 8q5i:7
16 7qiw:Y 62 65 0.3636 0.3871 0.3692 1.06e-08 7qiz:Y
17 5ndg:n4 118 65 0.3788 0.2119 0.3846 4.03e-08
18 5dat:n4 135 65 0.3788 0.1852 0.3846 5.55e-08 8aaf:J, 8agt:J, 8agu:J, 8agv:J, 8agw:J, 8agx:J, 8agz:J, 5apn:W, 5apo:W, 7azy:f, 7b7d:LS, 8bip:LW, 8bjq:LW, 8bn3:N4, 8bqd:AE, 8bqx:AE, 8ccs:I, 8cdl:I, 8cdr:I, 8ceh:I, 8cf5:I, 8cg8:I, 8cgn:I, 8civ:I, 8cku:I, 8cmj:I, 5dat:N4, 5dc3:N4, 5dc3:n4, 5dge:N4, 5dge:n4, 5dgf:N4, 5dgf:n4, 5dgv:N4, 5dgv:n4, 8eub:AW, 8evp:AW, 8evq:AW, 8evr:AW, 8evs:AW, 8evt:AW, 8ewb:AW, 8ewc:AW, 5fci:N4, 5fci:n4, 5fcj:N4, 5fcj:n4, 5gak:Y, 6gq1:W, 6gqb:W, 6gqv:W, 5h4p:W, 6hd7:Y, 6hhq:7, 6hhq:CY, 5i4l:N4, 5i4l:n4, 6i7o:AE, 6i7o:XE, 5it7:WW, 3j6x:64, 3j6y:64, 3j77:74, 3j78:74, 5juo:BA, 5jup:BA, 5jus:BA, 5jut:BA, 5juu:BA, 8k2d:LW, 8k82:LW, 5lyb:N4, 5lyb:n4, 5m1j:W5, 5mc6:AE, 5mei:7, 5mei:CY, 7mpi:AW, 7mpj:AW, 6n8m:j, 6n8n:j, 6n8o:j, 7n8b:AW, 5ndg:N4, 5ndv:N4, 5ndv:n4, 5ndw:N4, 5ndw:n4, 7nrc:LY, 7nrd:LY, 5obm:N4, 5obm:n4, 6oig:W, 5on6:7, 5on6:CY, 7osa:eL24, 7osm:eL24, 8p8m:QW, 8p8n:QW, 8p8u:QW, 8pfr:QW, 6q8y:AE, 6qik:v, 6qt0:v, 6qtz:v, 6r84:Y, 6r86:Y, 6r87:Y, 6ri5:v, 7rr5:LW, 6rzz:v, 6s05:v, 6s47:AY, 6snt:at, 6sv4:AE, 6sv4:XE, 6sv4:zE, 6t4q:LW, 5t62:j, 5t6r:j, 6t7i:LW, 6t7t:LW, 6t83:Wy, 6t83:H, 5tbw:7, 5tbw:CY, 6tb3:AE, 5tga:N4, 5tga:n4, 5tgm:N4, 5tgm:n4, 6tnu:AE, 7too:AL24, 7top:AL24, 4u3m:N4, 4u3m:n4, 4u3n:N4, 4u3n:n4, 4u3u:N4, 4u3u:n4, 4u4n:N4, 4u4n:n4, 4u4o:N4, 4u4o:n4, 4u4q:N4, 4u4q:n4, 4u4r:N4, 4u4r:n4, 4u4u:N4, 4u4u:n4, 4u4y:N4, 4u4y:n4, 4u4z:N4, 4u4z:n4, 4u50:N4, 4u50:n4, 4u51:N4, 4u51:n4, 4u52:N4, 4u52:n4, 4u53:N4, 4u53:n4, 4u55:N4, 4u55:n4, 4u56:N4, 4u56:n4, 4u6f:N4, 4u6f:n4, 6uz7:AW, 4v4b:BS, 4v6i:BZ, 4v7h:BS, 4v7r:BV, 4v7r:DV, 4v88:BW, 4v88:DW, 4v8t:W, 4v8y:BW, 4v8z:BW, 4v91:W, 6woo:W, 6xiq:W, 6xir:W, 8y0u:LW, 6z6j:LW, 6z6k:LW, 7zpq:BV, 7zrs:BV, 7zs5:BX, 7zuw:BV, 7zux:EV, 7zw0:LZ
19 7ohx:u 100 61 0.3333 0.2200 0.3607 1.02e-07 7oht:u
20 3j79:0 62 66 0.3333 0.3548 0.3333 1.13e-07 3jbn:A0, 3jbo:A0, 3jbp:A0, 8tpu:A0, 5umd:0
21 8pv1:CQ 183 61 0.3485 0.1257 0.3770 1.74e-07 8i9r:CQ, 8i9t:CQ, 8i9v:CQ, 8i9w:CQ, 8i9x:CQ, 8i9y:CQ, 8i9z:CQ, 8ia0:CQ, 8pv2:CQ, 8pv3:CQ, 8pv4:CQ, 8pv5:CQ, 8pv6:CQ, 8pv7:CQ, 8pv8:CQ, 8pvk:CQ, 8pvl:CQ
22 4v3p:LZ 75 66 0.3333 0.2933 0.3333 2.45e-07 8azw:L, 8b2l:L3, 8ip8:OA, 8ipa:OA, 8ipb:OA, 8jiv:CW, 4v7e:CW
23 8hfr:tB 154 61 0.3333 0.1429 0.3607 2.68e-07 7bt6:u, 7btb:u, 6c0f:u, 6elz:u, 6em1:u, 6ft6:u, 3jct:u, 6m62:u, 6n8j:u, 6n8k:u, 6n8l:u, 7nac:u, 7naf:u, 7of1:u, 7oh3:u, 7ohq:u, 7ohr:u, 7ohs:u, 7ohu:u, 7ohv:u, 7ohy:u, 7r7a:u, 7u0h:u, 7ug6:u, 7uoo:u, 7uqb:u, 7uqz:u, 7v08:u, 8v83:u, 8v84:u, 8v87:u, 6ylg:u, 6ylh:u, 6ylx:u, 6yly:u, 7z34:u
24 5xxb:V 63 65 0.3333 0.3492 0.3385 3.34e-07
25 7pwg:W 65 62 0.3485 0.3538 0.3710 5.45e-07 8fru:W, 7pwo:W2
26 7bhp:LW 42 60 0.3333 0.5238 0.3667 1.38e-06
27 4v4n:AV 66 56 0.2879 0.2879 0.3393 1.69e-06 6skf:BY, 6skg:BY, 6th6:BY, 4v6u:BV
28 7qep:N4 89 57 0.3333 0.2472 0.3860 2.05e-05
29 4v8p:BT 61 64 0.3333 0.3607 0.3438 5.13e-05 4v8p:CT, 4v8p:ET, 4v8p:GT
30 6zu5:LW0 93 60 0.3333 0.2366 0.3667 3.23e-04
31 6rm3:LW0 90 61 0.2727 0.2000 0.2951 0.17
32 1ibj:A 380 37 0.1818 0.0316 0.3243 0.96 1ibj:C
33 5g5s:A 692 32 0.1667 0.0159 0.3438 3.0 5g5t:A
34 3qhx:A 377 12 0.1212 0.0212 0.6667 3.2 3qhx:B
35 1lba:A 146 41 0.1970 0.0890 0.3171 3.6
36 4kvm:E 153 41 0.2273 0.0980 0.3659 4.4 4kvm:F, 4kvm:G, 4kvm:H, 4kvo:E, 4kvo:F, 4kvo:G, 4kvo:H, 4kvx:A, 4kvx:B
37 2i3g:A 347 21 0.1364 0.0259 0.4286 4.4 2i3g:B, 7nnq:A, 7nnq:B, 7nnq:C, 7nnq:D, 7nnr:A, 7nnr:B, 7not:A, 7not:B, 7not:C, 7not:D, 7nph:C, 7npj:B
38 8p5d:LW0 102 57 0.2121 0.1373 0.2456 5.6 8p60:LW0, 8p60:KW0, 7qca:LW0
39 8i9v:Cb 642 18 0.1515 0.0156 0.5556 6.7 8i9t:Cb, 8i9w:Cb, 8i9x:Cb
40 7pvn:B 990 21 0.1364 0.0091 0.4286 7.4 7sol:C
41 2hs3:A 602 32 0.2121 0.0233 0.4375 7.5 3d54:A, 3d54:E, 3d54:I, 2hs4:A
42 7sol:A 1011 21 0.1364 0.0089 0.4286 7.6 7pvn:A
43 3ihb:A 450 33 0.1818 0.0267 0.3636 8.1 3age:A, 3age:B, 3iha:A, 3iha:B, 3ihb:B
44 7pkt:z 53 29 0.1818 0.2264 0.4138 8.1
45 2hru:A 581 32 0.2121 0.0241 0.4375 8.3 2hry:A, 2hs0:A
46 3bga:A 1003 41 0.1818 0.0120 0.2927 8.9 3bga:B
47 8j6n:A 390 16 0.1212 0.0205 0.5000 9.3 8j6n:D, 8j6n:B, 8j6n:C, 8j6n:E, 8j6n:H, 8j6n:J, 8j6n:K, 8j6n:F, 8j6n:G, 8j6n:I, 8j6n:L

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023)(download the PDF file).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • zhanglabzhanggroup.org | +65-6601-1241 | Computing 1, 13 Computing Drive, Singapore 117417