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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MLTTLIYRSQVHPDRPPVDLDALVHRASSKNLPLGITGILLFNGLQFFQVLEGTEEALESLFSEIQSDPRHRDVVELMRD
YSAYRRFHGTGMRILDLRLFETDGALEEILRFSTPVNDRMFRLLSAFIADGGRYCLPEPLQPSRWMMMPATAAPQHLPGQ
PCQFALQAIVEPAKKRVSSFEALIRSPTGGSPVEMFAAIAAEDRYRFDLESKAYAFALAGQLPLGKHQLAINLLPGSLYH
HPDAVGWLMDSLLAAGLRPDQVLIEVTETEVITCFDQFRKVLKALRVAGMKLAIDDFGAGYSGLSLLTRFQPDKIKVDAE
LVRDIHISGTKQAIVASVVRCCEDLGITVVAEGVETLEEWCWLQSVGIRLFQGFLFSRPCLNGIGEICWPVA

The query sequence (length=392) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 3gfx:B 394 397 0.9898 0.9848 0.9773 0.0 3gfx:A, 3gfz:A, 3gfz:B, 3gg0:A, 3gg0:B, 3gg1:A, 3gg1:B, 2kb2:A
2 3gfy:B 374 397 0.9388 0.9840 0.9270 0.0 3gfy:A
3 6ifq:B 237 215 0.1837 0.3038 0.3349 1.42e-40 6ifq:A, 6ih1:A, 6ih1:B, 6ih1:C, 6ih1:D, 6ih7:B, 6ih7:A, 6ij2:A, 6ij2:B, 6ij2:C, 6ij2:D, 6k6t:A, 6k6t:B, 6k6t:C, 6k6t:D
4 3n3t:B 261 222 0.1913 0.2874 0.3378 4.63e-24 3n3t:A, 2r6o:A, 2r6o:B
5 4hjf:A 263 159 0.1531 0.2281 0.3774 8.77e-22 3u2e:A, 3u2e:B
6 8arv:A 255 153 0.1454 0.2235 0.3725 1.77e-21 8arv:B
7 5m3c:B 426 151 0.1327 0.1221 0.3444 1.16e-19 5m3c:A
8 5m1t:A 247 152 0.1276 0.2024 0.3289 2.26e-19 5m1t:B
9 5mf5:A 256 118 0.1148 0.1758 0.3814 3.59e-19 5mfu:A, 5mkg:A, 5mkg:B, 4y8e:A, 4y8e:B, 4y9p:A, 4y9p:B
10 3sy8:D 371 123 0.1250 0.1321 0.3984 1.70e-18
11 3sy8:B 392 123 0.1250 0.1250 0.3984 2.03e-18 3sy8:A, 3sy8:C
12 6hq7:A 377 243 0.1913 0.1989 0.3086 3.12e-17 6hq3:B, 6hq3:C, 6hq3:A, 6hq3:D, 6hq4:A, 6hq4:B, 6hq5:A, 6hq5:B, 6hq7:B
13 5yrp:A 224 127 0.1224 0.2143 0.3780 5.08e-16 5yrp:B
14 2byc:A 137 94 0.0969 0.2774 0.4043 9.93e-16 2byc:B
15 4rnh:A 423 128 0.1020 0.0946 0.3125 1.02e-14
16 4lj3:A 256 119 0.0969 0.1484 0.3193 2.53e-14 4lj3:B, 4lyk:A, 4lyk:B, 4lyk:C, 4lyk:D
17 6pwj:A 408 153 0.1020 0.0980 0.2614 4.95e-10 6pwj:B, 6pwk:A, 6pwk:B
18 2bun:A 121 93 0.0867 0.2810 0.3656 1.84e-09
19 5xgd:A 548 121 0.0893 0.0639 0.2893 3.46e-09 8pps:A, 8pps:B, 5xge:A
20 4fok:A 264 148 0.0867 0.1288 0.2297 7.41e-08 4f3h:A, 4f48:A, 4foj:A, 4fou:A, 4fou:B, 7lkq:A
21 2hfo:A 150 114 0.0893 0.2333 0.3070 1.50e-07 2hfn:A, 2hfn:B, 2hfn:C, 2hfn:D, 2hfn:E, 2hfn:F, 2hfn:G, 2hfn:H, 2hfn:I, 2hfn:J, 2hfo:B, 2hfo:C, 2hfo:D, 2hfo:E, 2hfo:F, 2hfo:G, 2hfo:H, 2hfo:I, 2hfo:J, 3mzi:A, 3mzi:B, 3mzi:C, 3mzi:D, 3mzi:E, 3mzi:F
22 4hh0:A 383 187 0.1276 0.1305 0.2674 2.03e-07 4hh0:B, 4hh1:A, 4hh1:B, 2iyg:A, 2iyg:B, 2iyi:A, 2iyi:B, 1yrx:A, 1yrx:B, 1yrx:C
23 3pju:A 249 161 0.1020 0.1606 0.2484 2.94e-07 3pjt:A, 3pjt:B
24 2w27:A 401 224 0.1301 0.1272 0.2277 3.76e-07 2w27:B
25 6w6z:A 151 76 0.0714 0.1854 0.3684 7.08e-07 6w72:A, 6w72:B
26 3kzp:B 232 233 0.1454 0.2457 0.2446 8.14e-07 3kzp:A
27 4afy:B 250 153 0.0867 0.1360 0.2222 8.00e-06 4afy:A, 4ag0:A, 4ag0:B, 3hv8:A
28 5m2a:A 346 99 0.0714 0.0809 0.2828 1.08e-05 5m27:A, 5m27:B, 5m2a:B, 5mbb:A, 5mbb:B, 5mbc:A, 5mbc:B, 5mbd:A, 5mbd:B, 5mbe:A, 5mbe:B, 5mbh:A, 5mbj:A, 5mbk:A, 5nby:A
29 8i98:F 143 95 0.0689 0.1888 0.2842 1.54e-05 8i98:A, 8i98:B, 8i98:C, 8i98:D, 8i98:E, 8i98:G, 8i98:H, 8i98:I, 8i98:J, 8i98:K, 8i98:L, 8i98:M, 8i98:N, 8i98:O, 8i98:P, 8i98:Q, 8i98:R, 8i98:S, 8i98:T, 1x0p:A, 1x0p:B, 1x0p:C, 1x0p:D, 1x0p:E, 1x0p:F, 1x0p:G, 1x0p:H, 1x0p:I, 1x0p:J
30 4yut:A 351 81 0.0663 0.0741 0.3210 4.83e-05 8qfe:A, 8qff:A, 8qfg:A, 8qfh:A, 8qfi:A, 8qfj:A, 5x4t:A, 5x4u:A, 5x4v:A, 4yus:A, 4yut:B
31 5hj9:A 311 95 0.0740 0.0932 0.3053 0.23 5hja:A, 4ity:A, 4iu0:A, 4iu1:A, 4iu4:A, 4iu5:A
32 5d00:A 361 83 0.0536 0.0582 0.2530 0.75 5d00:B, 5d01:A, 5d01:B
33 7xf0:C 598 69 0.0485 0.0318 0.2754 1.1 7xf0:A, 7xf0:B, 7xf1:A, 7xg3:L, 7xg4:L
34 2x8u:A 399 141 0.0867 0.0852 0.2411 1.7 2x8u:B
35 3zyv:B 1262 71 0.0638 0.0198 0.3521 2.2 3zyv:A, 3zyv:C, 3zyv:D
36 8axs:A 573 119 0.0663 0.0454 0.2185 2.3 8axi:A, 8axi:B, 8axs:B, 8axt:A, 8axt:B, 8hls:A, 8hls:B
37 5dqr:C 421 69 0.0485 0.0451 0.2754 3.8 5dqr:A, 5dqr:B, 5dqr:D, 5dqr:E, 5dqr:F
38 5cwe:A 393 30 0.0332 0.0331 0.4333 4.3 5cje:A, 5cwe:B
39 9c4g:o 114 43 0.0357 0.1228 0.3256 6.5 8crx:o, 8cvm:o
40 4w6q:B 332 73 0.0536 0.0633 0.2877 9.3 4w6q:A, 4w6q:C, 4w6q:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218