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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MLPLYLLTNAKGQQMQIELKNGEIIQGILTNVDNWMNLTLSNVTEYSVKLNEIYIRGTFIKFIKLQDNIIDKVK

The query sequence (length=74) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5gan:4 74 74 1.0000 1.0000 1.0000 2.35e-48 4m7a:N, 4m7a:G, 4m7d:N, 5nrl:j, 5vsu:D
2 6aso:D 59 67 0.7973 1.0000 0.8806 1.86e-34
3 6ppn:D 88 79 0.4730 0.3977 0.4430 9.99e-17 6ppn:L, 6ppp:D, 6ppp:L, 6ppq:D, 6ppv:D
4 6qw6:64 73 72 0.4189 0.4247 0.4306 3.45e-14 6qx9:64
5 8c6j:d 84 71 0.3108 0.2738 0.3239 7.37e-08 7a5p:l, 7a5p:a, 7abg:e, 7abg:l, 7abi:l, 6ah0:h, 6ah0:T, 6ahd:g, 6ahd:h, 7b0y:i, 8c6j:n, 8ch6:j, 8ch6:3, 7dvq:h, 7evo:e, 9fmd:h, 9fmd:a, 8h6e:5g, 8h6e:4g, 8h6e:2g, 8h6j:5g, 8h6j:4g, 8h6j:2g, 8h6k:5g, 8h6k:2g, 8h6l:5g, 8h6l:2g, 8hk1:e, 8i0p:g, 8i0p:l, 8i0r:g, 8i0r:l, 8i0s:g, 8i0s:l, 8i0t:g, 8i0t:l, 8i0u:g, 8i0u:l, 8i0v:g, 8i0v:l, 8i0w:g, 8i0w:h, 6id1:a, 5mqf:l, 5o9z:W, 5o9z:e, 4pjo:A, 4pjo:a, 4pjo:O, 4pjo:o, 8q7q:d, 8q7v:d, 8q7w:d, 8q7x:d, 6qdv:n, 6qdv:d, 8qo9:23, 8qo9:53, 8qo9:43, 7qtt:j, 6qw6:43, 6qw6:53, 6qx9:13, 6qx9:53, 6qx9:23, 6qx9:43, 8qxd:23, 8qxd:43, 8qzs:53, 8qzs:23, 8qzs:43, 8r08:13, 8r08:23, 8r08:43, 8r09:23, 8r09:53, 8r09:43, 8r0a:53, 8r0a:23, 8r0a:43, 8r0b:23, 8r0b:43, 8r0b:53, 8rm5:23, 8rm5:43, 8ro2:a, 6v4x:A, 7vpx:e, 7vpx:j, 7w59:a, 7w59:h, 7w5a:a, 7w5a:h, 7w5b:a, 7w5b:h, 4wzj:A, 4wzj:H, 4wzj:O, 4wzj:AA, 4wzj:HH, 4wzj:OO, 4wzj:AAA, 4wzj:HHH, 4wzj:OOO, 4wzj:AAAA, 4wzj:HHHH, 4wzj:OOOO, 5xjc:a, 5xjc:h, 6y53:l, 6y5q:l, 8y6o:d, 8y6o:k, 8y6o:r, 8y7e:h, 5yzg:a, 5yzg:h, 5z56:a, 5z56:h, 5z57:a, 5z57:h, 5z58:a, 5z58:h
6 6g90:d 93 71 0.3243 0.2581 0.3380 1.35e-06 7b9v:n, 7b9v:d, 6bk8:o, 6bk8:g, 7dco:l, 6exn:n, 6exn:d, 6g90:v, 5gam:d, 5gan:n, 5gan:d, 5gao:n, 5gm6:l, 5gmk:l, 5gmk:y, 6j6g:l, 6j6g:y, 6j6h:l, 6j6h:y, 6j6n:l, 6j6n:y, 6j6q:l, 6j6q:y, 3jcm:J, 3jcm:R, 5lj3:d, 5lj3:n, 5lj5:d, 5lj5:n, 5mps:d, 5mq0:n, 5mq0:d, 6n7p:N, 6n7r:N, 6n7x:N, 5nrl:v, 5nrl:n, 5nrl:d, 7oqb:v, 7oqc:d, 7oqe:d, 7oqe:v, 8w2o:N, 5wsg:l, 5wsg:U, 5y88:e, 5y88:l, 5ylz:e, 5ylz:l, 5zwm:S, 5zwm:d, 5zwm:l, 5zwn:d, 5zwo:d, 5zwo:S
7 6ppn:B 94 67 0.2297 0.1809 0.2537 1.42e-06 6ppn:J, 6ppp:B, 6ppp:J, 6ppq:B, 6ppv:B
8 6v4x:C 114 69 0.2432 0.1579 0.2609 2.04e-06
9 5vsu:B 98 78 0.3243 0.2449 0.3077 2.67e-06 6aso:B, 5gan:2, 4m7a:I, 4m7a:B, 4m7d:I, 4m7d:B, 5nrl:a
10 8ro0:a 81 71 0.2838 0.2593 0.2958 5.74e-06 8ro1:a
11 3jb9:D 96 71 0.2703 0.2083 0.2817 2.13e-05 3jb9:Z
12 6qw6:62 95 67 0.2297 0.1789 0.2537 2.89e-05 6ahd:q, 8h6e:6a, 8h6j:6a, 8h6k:6a, 8h6l:6a, 6qx9:62
13 8ro0:c 80 60 0.3108 0.2875 0.3833 5.37e-05 8ro1:c
14 3jb9:F 82 62 0.2973 0.2683 0.3548 5.64e-05 3jb9:f
15 4wzj:MM 80 67 0.2973 0.2750 0.3284 1.09e-04 7abg:b, 7abi:b, 6ahd:Q, 6ahd:d, 7b0y:f, 8c6j:q, 8c6j:f, 8ch6:h, 8ch6:2, 7dvq:f, 7dvq:m, 9fmd:m, 9fmd:f, 8h6e:5d, 8h6e:4d, 8h6j:5d, 8h6j:4d, 8h6k:5d, 8h6k:4d, 8h6l:5d, 8h6l:4d, 8i0p:d, 8i0r:d, 8i0s:d, 8i0s:i, 8i0t:d, 8i0t:i, 8i0u:d, 8i0u:i, 8i0v:d, 8i0v:i, 8i0w:d, 8i0w:m, 6id1:f, 5mqf:i, 5mqf:b, 5o9z:i, 4pjo:F, 4pjo:f, 4pjo:T, 4pjo:t, 8q7q:f, 8q7v:f, 8q7w:f, 8q7x:f, 8q91:m, 6qdv:q, 6qdv:f, 8qo9:2f, 8qo9:5f, 8qo9:4f, 7qtt:h, 6qw6:4f, 6qw6:5f, 6qx9:1f, 6qx9:5f, 6qx9:2f, 6qx9:4f, 8qxd:2f, 8qxd:4f, 8qxd:5f, 8qzs:5f, 8qzs:2f, 8qzs:4f, 8r08:1f, 8r08:2f, 8r08:4f, 8r08:5f, 8r09:2f, 8r09:5f, 8r09:4f, 8r0a:5f, 8r0a:2f, 8r0a:4f, 8r0b:2f, 8r0b:4f, 8r0b:5f, 8rc0:m, 8rm5:2f, 8rm5:5f, 8rm5:4f, 8ro2:f, 6v4x:F, 7vpx:m, 7w59:f, 7w59:m, 7w5a:f, 7w5a:m, 7w5b:f, 7w5b:m, 4wzj:F, 4wzj:M, 4wzj:T, 4wzj:FF, 4wzj:TT, 4wzj:FFF, 4wzj:MMM, 4wzj:TTT, 4wzj:FFFF, 4wzj:MMMM, 4wzj:TTTT, 5xjc:f, 5xjc:m, 8y6o:f, 8y6o:m, 8y6o:t, 8y7e:m, 5yzg:f, 5yzg:m, 5z56:m, 5z57:m, 5z58:m
16 4m7a:F 66 56 0.2568 0.2879 0.3393 1.22e-04
17 5vsu:F 77 70 0.2432 0.2338 0.2571 1.30e-04 6aso:F
18 5nrl:l 99 66 0.3378 0.2525 0.3788 0.003 6bk8:h, 7dco:m, 6exn:h, 6g90:t, 5gam:h, 5gan:l, 5gan:h, 5gao:l, 5gm6:m, 5gmk:m, 5gmk:z, 5lj3:h, 5lj3:l, 5lj5:h, 5lj5:l, 5mps:h, 5mq0:h, 5nrl:t, 5nrl:h, 7oqb:t, 7oqe:t, 5wsg:m, 5wsg:V, 5y88:f, 5y88:m, 5ylz:f, 5ylz:m, 5zwm:Q, 5zwm:m, 5zwo:Q, 5zwo:m
19 7abg:g 93 63 0.2838 0.2258 0.3333 0.004 7a5p:n, 7abg:n, 7abi:n, 7abi:g, 6ah0:V, 6ahd:b, 7b0y:k, 8c6j:l, 8c6j:c, 8ch6:k, 8ch6:5, 7dvq:c, 7dvq:j, 9fmd:c, 9fmd:j, 8h6e:5b, 8h6e:4b, 8h6j:5b, 8h6j:4b, 8h6k:5b, 8h6l:5b, 8i0p:b, 8i0p:n, 8i0r:b, 8i0r:n, 8i0s:b, 8i0s:n, 8i0t:b, 8i0t:n, 8i0u:b, 8i0u:n, 8i0v:b, 8i0v:n, 8i0w:b, 8i0w:j, 6icz:j, 6id0:j, 6id1:j, 5mqf:g, 5o9z:n, 5o9z:g, 4pjo:C, 4pjo:c, 4pjo:Q, 4pjo:q, 8q7q:a, 8q7v:a, 8q7w:a, 8q7x:a, 8q91:i, 6qdv:l, 6qdv:h, 8qo9:21, 8qo9:51, 8qo9:41, 7qtt:k, 6qw6:41, 6qw6:51, 6qx9:11, 6qx9:51, 6qx9:21, 6qx9:41, 8qxd:21, 8qxd:41, 8qxd:51, 8qzs:51, 8qzs:21, 8r08:11, 8r08:41, 8r08:21, 8r08:51, 8r09:21, 8r09:51, 8r09:41, 8r0a:51, 8r0a:21, 8r0a:41, 8r0b:21, 8r0b:41, 8r0b:51, 8rc0:i, 8rm5:21, 8rm5:51, 8rm5:41, 8ro2:c, 7vpx:h, 7w59:c, 7w59:j, 7w5a:c, 7w5a:j, 7w5b:c, 7w5b:j, 4wzj:C, 4wzj:J, 4wzj:Q, 4wzj:CC, 4wzj:JJ, 4wzj:QQ, 4wzj:CCC, 4wzj:JJJ, 4wzj:QQQ, 4wzj:CCCC, 4wzj:JJJJ, 4wzj:QQQQ, 5xjc:c, 5xjc:j, 8y6o:b, 8y6o:i, 8y6o:p, 8y7e:j, 5yzg:c, 5yzg:j, 5z56:c, 5z56:j, 5z57:c, 5z57:j, 5z58:c, 5z58:j
20 6kjj:A 361 57 0.2568 0.0526 0.3333 0.005 6kjp:A, 6kjq:A, 6kjr:A
21 6qw6:66 72 69 0.2568 0.2639 0.2754 0.005 6qx9:66
22 6ppq:F 71 66 0.2838 0.2958 0.3182 0.005 6ppn:F, 6ppn:N, 6ppp:F, 6ppp:N, 6ppv:F
23 3jb9:E 98 58 0.2432 0.1837 0.3103 0.008 3jb9:b
24 1lnx:A 74 54 0.2297 0.2297 0.3148 0.009 1lnx:B, 1lnx:C, 1lnx:D, 1lnx:E, 1lnx:F, 1lnx:G
25 8ro0:f 72 59 0.2838 0.2917 0.3559 0.009 8ro1:f
26 8ro0:n 77 62 0.2297 0.2208 0.2742 0.024 8ro0:g, 8ro1:g
27 1loj:C 77 66 0.2838 0.2727 0.3182 0.024 1loj:A, 1loj:B, 1loj:D, 1loj:E, 1loj:F, 1loj:G, 1loj:H, 1loj:I, 1loj:J, 1loj:K, 1loj:L, 1loj:M, 1loj:N
28 3jb9:I 73 59 0.2838 0.2877 0.3559 0.044 3jb9:n
29 6v4x:G 77 64 0.2027 0.1948 0.2344 0.056 7a5p:k, 7a5p:g, 7abg:k, 7abi:k, 6ah0:n, 6ahd:S, 6ahd:f, 6ahd:n, 7b0y:h, 8c6j:r, 8c6j:g, 8ch6:m, 8ch6:9, 7dvq:g, 7dvq:n, 7evo:d, 9fmd:n, 9fmd:g, 8h6e:5f, 8h6e:4f, 8h6e:2f, 8h6j:5f, 8h6j:4f, 8h6j:2f, 8h6k:5f, 8h6k:4f, 8h6k:2f, 8h6l:5f, 8h6l:4f, 8h6l:2f, 8hk1:d, 8i0p:k, 8i0r:k, 8i0s:f, 8i0s:k, 8i0t:k, 8i0u:f, 8i0u:k, 8i0v:k, 8i0w:n, 6icz:g, 6id0:g, 6id1:g, 5mqf:k, 5mqf:d, 5o9z:k, 4pjo:G, 4pjo:g, 4pjo:U, 4pjo:u, 8q7q:g, 8q7v:g, 8q7w:g, 8q7x:g, 8q91:n, 6qdv:r, 6qdv:g, 8qo9:2g, 8qo9:4g, 7qtt:m, 6qw6:4g, 6qw6:5g, 6qx9:1g, 6qx9:5g, 6qx9:2g, 6qx9:4g, 8qxd:2g, 8qxd:4g, 8qxd:5g, 8qzs:5g, 8qzs:2g, 8qzs:4g, 8r08:1g, 8r08:2g, 8r08:4g, 8r08:5g, 8r09:2g, 8r09:5g, 8r09:4g, 8r0a:5g, 8r0a:2g, 8r0a:4g, 8r0b:2g, 8r0b:4g, 8r0b:5g, 8rc0:n, 8rm5:2g, 8rm5:5g, 8rm5:4g, 8ro2:g, 7vpx:d, 7vpx:n, 7w59:g, 7w59:n, 7w5a:g, 7w5a:n, 7w5b:g, 7w5b:n, 4wzj:G, 4wzj:N, 4wzj:U, 4wzj:GG, 4wzj:NN, 4wzj:UU, 4wzj:GGG, 4wzj:NNN, 4wzj:UUU, 4wzj:GGGG, 4wzj:NNNN, 4wzj:UUUU, 5xjc:g, 5xjc:n, 6y53:k, 6y5q:k, 8y6o:g, 8y6o:n, 8y6o:u, 8y7e:n, 5yzg:g, 5yzg:n, 5z56:g, 5z56:n, 5z57:g, 5z57:n, 5z58:g, 5z58:n
30 6am0:D 65 35 0.2162 0.2462 0.4571 0.061
31 6g90:h 107 73 0.2568 0.1776 0.2603 0.095 6exn:l, 7oqc:h, 7oqe:h
32 1i5l:C 74 66 0.2568 0.2568 0.2879 0.14 1i5l:E, 1i5l:F, 1i5l:G, 1i5l:J, 1i5l:K, 1i5l:L, 1i5l:A, 1i5l:B, 1i5l:H
33 6j6g:m 119 49 0.2432 0.1513 0.3673 0.17 7b9v:l, 7b9v:h, 6j6g:z, 6j6h:m, 6j6h:z, 6j6n:m, 6j6n:z, 6j6q:m, 6j6q:z, 6n7p:L, 6n7r:L, 6n7x:L, 8w2o:L, 5zwn:b
34 6tfl:A 62 40 0.1622 0.1935 0.3000 0.18 6tfl:B, 6tfl:C, 6tfl:D, 6tfl:E, 6tfl:F, 6tfl:G, 6tfl:H, 6tfl:I, 6tfl:J, 6tfl:K, 6tfl:L, 6tfl:M, 6tfl:N
35 5mkn:d 72 66 0.2432 0.2500 0.2727 0.58 5mki:C, 5mki:D, 5mki:E, 5mki:F, 5mki:G, 5mki:I, 5mki:J, 5mki:K, 5mki:L, 5mkn:A, 5mkn:G, 5mkn:B, 5mkn:C, 5mkn:D, 5mkn:E, 5mkn:F, 5mkn:H, 5mkn:I, 5mkn:J, 5mkn:K, 5mkn:L, 5mkn:M, 5mkn:N, 5mkn:O, 5mkn:P, 5mkn:Q, 5mkn:R, 5mkn:T, 5mkn:U, 5mkn:V, 5mkn:W, 5mkn:X, 5mkn:Y, 5mkn:Z, 5mkn:a, 5mkn:b
36 7b9v:q 75 58 0.2297 0.2267 0.2931 0.66 7b9v:f, 6bk8:b, 7dco:j, 6exn:q, 6exn:f, 6g90:f, 6g90:x, 5gam:f, 5gan:q, 5gan:f, 5gao:q, 5gm6:h, 5gmk:h, 5gmk:w, 6j6g:h, 6j6g:w, 6j6h:h, 6j6h:w, 6j6n:h, 6j6n:w, 6j6q:h, 6j6q:w, 5lj3:f, 5lj5:f, 5mps:f, 5mq0:f, 6n7p:P, 6n7r:P, 6n7x:P, 5nrl:x, 5nrl:q, 5nrl:f, 7oqc:f, 8w2o:P, 5wsg:h, 5wsg:H, 5y88:c, 5y88:j, 5ylz:c, 5ylz:j, 5zwm:U, 5zwm:j, 5zwn:f, 5zwo:U, 5zwo:j
37 5dy9:E 60 24 0.1216 0.1500 0.3750 1.3 5dy9:A, 5dy9:F, 5dy9:D, 5dy9:G, 5dy9:L, 4x9d:A, 4x9d:F, 4x9d:B, 4x9d:C, 4x9d:D, 4x9d:E
38 7eap:A 755 67 0.3243 0.0318 0.3582 1.7 5yot:A, 5yot:B, 5yqs:A, 5yqs:B
39 3vuv:A 276 51 0.2027 0.0543 0.2941 2.7
40 1cm5:A 759 42 0.1486 0.0145 0.2619 6.8 1cm5:B, 1h16:A, 1h17:A, 1h18:A, 1h18:B, 1mzo:A, 1mzo:B
41 1bxr:A 1073 36 0.1351 0.0093 0.2778 8.3 1a9x:A, 1a9x:C, 1a9x:E, 1a9x:G, 1bxr:C, 1bxr:E, 1bxr:G, 1c30:A, 1c30:C, 1c30:E, 1c30:G, 1c3o:A, 1c3o:C, 1c3o:E, 1c3o:G, 1ce8:A, 1ce8:C, 1ce8:E, 1ce8:G, 1cs0:A, 1cs0:C, 1cs0:E, 1cs0:G, 1jdb:B, 1jdb:E, 1jdb:H, 1jdb:K, 1kee:A, 1kee:C, 1kee:E, 1kee:G, 1m6v:A, 1m6v:C, 1m6v:E, 1m6v:G, 1t36:A, 1t36:C, 1t36:E, 1t36:G

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218