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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MLFYSFFKTLIDTEVTVELKNDMSIRGILKSVDQFLNVKLENISVVDASKYPHMAAVKDLFIRGSVVRYVHMSSAYVDTI
LLADACRRDLANNK

The query sequence (length=94) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6ppn:B 94 94 1.0000 1.0000 1.0000 2.18e-65 6ppn:J, 6ppp:B, 6ppp:J, 6ppq:B, 6ppv:B
2 5vsu:B 98 94 0.6064 0.5816 0.6064 8.20e-40 6aso:B, 5gan:2, 4m7a:I, 4m7a:B, 4m7d:I, 4m7d:B, 5nrl:a
3 6qw6:62 95 94 0.6170 0.6105 0.6170 1.30e-37 6ahd:q, 8h6e:6a, 8h6j:6a, 8h6k:6a, 8h6l:6a, 6qx9:62
4 5nrl:l 99 82 0.2660 0.2525 0.3049 1.31e-07 6bk8:h, 7dco:m, 6exn:h, 6g90:t, 5gam:h, 5gan:l, 5gan:h, 5gao:l, 5gm6:m, 5gmk:m, 5gmk:z, 5lj3:h, 5lj3:l, 5lj5:h, 5lj5:l, 5mps:h, 5mq0:h, 5nrl:t, 5nrl:h, 7oqb:t, 7oqe:t, 5wsg:m, 5wsg:V, 5y88:f, 5y88:m, 5ylz:f, 5ylz:m, 5zwm:Q, 5zwm:m, 5zwo:Q, 5zwo:m
5 6v4x:C 114 57 0.2128 0.1754 0.3509 3.25e-07
6 5gan:4 74 67 0.1809 0.2297 0.2537 1.80e-06 4m7a:N, 4m7a:G, 4m7d:N, 5nrl:j, 5vsu:D
7 3jb9:F 82 83 0.2766 0.3171 0.3133 5.36e-06 3jb9:f
8 6qw6:64 73 74 0.2447 0.3151 0.3108 9.35e-06 6qx9:64
9 6g90:h 107 94 0.2553 0.2243 0.2553 4.64e-05 6exn:l, 7oqc:h, 7oqe:h
10 6aso:D 59 60 0.1702 0.2712 0.2667 1.15e-04
11 6qw6:66 72 65 0.2128 0.2778 0.3077 3.39e-04 6qx9:66
12 6ppn:D 88 91 0.2128 0.2273 0.2198 3.61e-04 6ppn:L, 6ppp:D, 6ppp:L, 6ppq:D, 6ppv:D
13 4wzj:MM 80 66 0.2340 0.2750 0.3333 7.64e-04 7abg:b, 7abi:b, 6ahd:Q, 6ahd:d, 7b0y:f, 8c6j:q, 8c6j:f, 8ch6:h, 8ch6:2, 7dvq:f, 7dvq:m, 9fmd:m, 9fmd:f, 8h6e:5d, 8h6e:4d, 8h6j:5d, 8h6j:4d, 8h6k:5d, 8h6k:4d, 8h6l:5d, 8h6l:4d, 8i0p:d, 8i0r:d, 8i0s:d, 8i0s:i, 8i0t:d, 8i0t:i, 8i0u:d, 8i0u:i, 8i0v:d, 8i0v:i, 8i0w:d, 8i0w:m, 6id1:f, 5mqf:i, 5mqf:b, 5o9z:i, 4pjo:F, 4pjo:f, 4pjo:T, 4pjo:t, 8q7q:f, 8q7v:f, 8q7w:f, 8q7x:f, 8q91:m, 6qdv:q, 6qdv:f, 8qo9:2f, 8qo9:5f, 8qo9:4f, 7qtt:h, 6qw6:4f, 6qw6:5f, 6qx9:1f, 6qx9:5f, 6qx9:2f, 6qx9:4f, 8qxd:2f, 8qxd:4f, 8qxd:5f, 8qzs:5f, 8qzs:2f, 8qzs:4f, 8r08:1f, 8r08:2f, 8r08:4f, 8r08:5f, 8r09:2f, 8r09:5f, 8r09:4f, 8r0a:5f, 8r0a:2f, 8r0a:4f, 8r0b:2f, 8r0b:4f, 8r0b:5f, 8rc0:m, 8rm5:2f, 8rm5:5f, 8rm5:4f, 8ro2:f, 6v4x:F, 7vpx:m, 7w59:f, 7w59:m, 7w5a:f, 7w5a:m, 7w5b:f, 7w5b:m, 4wzj:F, 4wzj:M, 4wzj:T, 4wzj:FF, 4wzj:TT, 4wzj:FFF, 4wzj:MMM, 4wzj:TTT, 4wzj:FFFF, 4wzj:MMMM, 4wzj:TTTT, 5xjc:f, 5xjc:m, 8y6o:f, 8y6o:m, 8y6o:t, 8y7e:m, 5yzg:f, 5yzg:m, 5z56:m, 5z57:m, 5z58:m
14 6j6g:m 119 106 0.2660 0.2101 0.2358 0.001 7b9v:l, 7b9v:h, 6j6g:z, 6j6h:m, 6j6h:z, 6j6n:m, 6j6n:z, 6j6q:m, 6j6q:z, 6n7p:L, 6n7r:L, 6n7x:L, 8w2o:L, 5zwn:b
15 5mkn:d 72 64 0.2553 0.3333 0.3750 0.002 5mki:C, 5mki:D, 5mki:E, 5mki:F, 5mki:G, 5mki:I, 5mki:J, 5mki:K, 5mki:L, 5mkn:A, 5mkn:G, 5mkn:B, 5mkn:C, 5mkn:D, 5mkn:E, 5mkn:F, 5mkn:H, 5mkn:I, 5mkn:J, 5mkn:K, 5mkn:L, 5mkn:M, 5mkn:N, 5mkn:O, 5mkn:P, 5mkn:Q, 5mkn:R, 5mkn:T, 5mkn:U, 5mkn:V, 5mkn:W, 5mkn:X, 5mkn:Y, 5mkn:Z, 5mkn:a, 5mkn:b
16 3jb9:I 73 67 0.2340 0.3014 0.3284 0.002 3jb9:n
17 6ppq:F 71 65 0.2128 0.2817 0.3077 0.003 6ppn:F, 6ppn:N, 6ppp:F, 6ppp:N, 6ppv:F
18 3jb9:D 96 56 0.1809 0.1771 0.3036 0.009 3jb9:Z
19 7abg:g 93 78 0.2553 0.2581 0.3077 0.013 7a5p:n, 7abg:n, 7abi:n, 7abi:g, 6ah0:V, 6ahd:b, 7b0y:k, 8c6j:l, 8c6j:c, 8ch6:k, 8ch6:5, 7dvq:c, 7dvq:j, 9fmd:c, 9fmd:j, 8h6e:5b, 8h6e:4b, 8h6j:5b, 8h6j:4b, 8h6k:5b, 8h6l:5b, 8i0p:b, 8i0p:n, 8i0r:b, 8i0r:n, 8i0s:b, 8i0s:n, 8i0t:b, 8i0t:n, 8i0u:b, 8i0u:n, 8i0v:b, 8i0v:n, 8i0w:b, 8i0w:j, 6icz:j, 6id0:j, 6id1:j, 5mqf:g, 5o9z:n, 5o9z:g, 4pjo:C, 4pjo:c, 4pjo:Q, 4pjo:q, 8q7q:a, 8q7v:a, 8q7w:a, 8q7x:a, 8q91:i, 6qdv:l, 6qdv:h, 8qo9:21, 8qo9:51, 8qo9:41, 7qtt:k, 6qw6:41, 6qw6:51, 6qx9:11, 6qx9:51, 6qx9:21, 6qx9:41, 8qxd:21, 8qxd:41, 8qxd:51, 8qzs:51, 8qzs:21, 8r08:11, 8r08:41, 8r08:21, 8r08:51, 8r09:21, 8r09:51, 8r09:41, 8r0a:51, 8r0a:21, 8r0a:41, 8r0b:21, 8r0b:41, 8r0b:51, 8rc0:i, 8rm5:21, 8rm5:51, 8rm5:41, 8ro2:c, 7vpx:h, 7w59:c, 7w59:j, 7w5a:c, 7w5a:j, 7w5b:c, 7w5b:j, 4wzj:C, 4wzj:J, 4wzj:Q, 4wzj:CC, 4wzj:JJ, 4wzj:QQ, 4wzj:CCC, 4wzj:JJJ, 4wzj:QQQ, 4wzj:CCCC, 4wzj:JJJJ, 4wzj:QQQQ, 5xjc:c, 5xjc:j, 8y6o:b, 8y6o:i, 8y6o:p, 8y7e:j, 5yzg:c, 5yzg:j, 5z56:c, 5z56:j, 5z57:c, 5z57:j, 5z58:c, 5z58:j
20 5vsu:F 77 67 0.2021 0.2468 0.2836 0.032 6aso:F
21 8ro0:f 72 67 0.1915 0.2500 0.2687 0.10 8ro1:f
22 6qw6:63 85 68 0.2021 0.2235 0.2794 0.13 6ah0:r, 6qx9:63, 8qxd:63, 8r08:63, 8r09:63, 8r0a:63, 8r0b:63, 8rm5:63
23 1loj:C 77 60 0.1702 0.2078 0.2667 0.14 1loj:A, 1loj:B, 1loj:D, 1loj:E, 1loj:F, 1loj:G, 1loj:H, 1loj:I, 1loj:J, 1loj:K, 1loj:L, 1loj:M, 1loj:N
24 4m7a:F 66 64 0.2021 0.2879 0.2969 0.22
25 3jb9:J 73 36 0.1383 0.1781 0.3611 0.23 3jb9:o
26 6ppq:A 69 31 0.1383 0.1884 0.4194 0.33 6ppv:A
27 8pe1:B 451 32 0.1170 0.0244 0.3438 0.88 8pe1:A, 8pe2:A
28 6v4x:G 77 32 0.0957 0.1169 0.2812 1.1 7a5p:k, 7a5p:g, 7abg:k, 7abi:k, 6ah0:n, 6ahd:S, 6ahd:f, 6ahd:n, 7b0y:h, 8c6j:r, 8c6j:g, 8ch6:m, 8ch6:9, 7dvq:g, 7dvq:n, 7evo:d, 9fmd:n, 9fmd:g, 8h6e:5f, 8h6e:4f, 8h6e:2f, 8h6j:5f, 8h6j:4f, 8h6j:2f, 8h6k:5f, 8h6k:4f, 8h6k:2f, 8h6l:5f, 8h6l:4f, 8h6l:2f, 8hk1:d, 8i0p:k, 8i0r:k, 8i0s:f, 8i0s:k, 8i0t:k, 8i0u:f, 8i0u:k, 8i0v:k, 8i0w:n, 6icz:g, 6id0:g, 6id1:g, 5mqf:k, 5mqf:d, 5o9z:k, 4pjo:G, 4pjo:g, 4pjo:U, 4pjo:u, 8q7q:g, 8q7v:g, 8q7w:g, 8q7x:g, 8q91:n, 6qdv:r, 6qdv:g, 8qo9:2g, 8qo9:4g, 7qtt:m, 6qw6:4g, 6qw6:5g, 6qx9:1g, 6qx9:5g, 6qx9:2g, 6qx9:4g, 8qxd:2g, 8qxd:4g, 8qxd:5g, 8qzs:5g, 8qzs:2g, 8qzs:4g, 8r08:1g, 8r08:2g, 8r08:4g, 8r08:5g, 8r09:2g, 8r09:5g, 8r09:4g, 8r0a:5g, 8r0a:2g, 8r0a:4g, 8r0b:2g, 8r0b:4g, 8r0b:5g, 8rc0:n, 8rm5:2g, 8rm5:5g, 8rm5:4g, 8ro2:g, 7vpx:d, 7vpx:n, 7w59:g, 7w59:n, 7w5a:g, 7w5a:n, 7w5b:g, 7w5b:n, 4wzj:G, 4wzj:N, 4wzj:U, 4wzj:GG, 4wzj:NN, 4wzj:UU, 4wzj:GGG, 4wzj:NNN, 4wzj:UUU, 4wzj:GGGG, 4wzj:NNNN, 4wzj:UUUU, 5xjc:g, 5xjc:n, 6y53:k, 6y5q:k, 8y6o:g, 8y6o:n, 8y6o:u, 8y7e:n, 5yzg:g, 5yzg:n, 5z56:g, 5z56:n, 5z57:g, 5z57:n, 5z58:g, 5z58:n
29 8p4q:E 390 49 0.1702 0.0410 0.3265 1.5 8p37:A, 8p4q:A, 8p4q:B, 8p4q:C, 8p4q:D, 8p4q:F, 8p4q:G, 8p4q:H
30 1vtm:P 158 28 0.1170 0.0696 0.3929 1.5
31 8ro0:n 77 32 0.1064 0.1299 0.3125 1.8 8ro0:g, 8ro1:g
32 3vkg:B 2853 35 0.1277 0.0042 0.3429 2.4
33 3vkh:B 2908 35 0.1277 0.0041 0.3429 2.4
34 3vkg:A 2954 35 0.1277 0.0041 0.3429 2.4
35 3vkh:A 3042 35 0.1277 0.0039 0.3429 2.4
36 3jb9:H 76 39 0.1277 0.1579 0.3077 3.1 3jb9:m
37 6tfl:A 62 28 0.1277 0.1935 0.4286 3.1 6tfl:B, 6tfl:C, 6tfl:D, 6tfl:E, 6tfl:F, 6tfl:G, 6tfl:H, 6tfl:I, 6tfl:J, 6tfl:K, 6tfl:L, 6tfl:M, 6tfl:N
38 8y6o:q 104 64 0.1702 0.1538 0.2500 3.3 7a5p:h, 7abg:a, 7abi:a, 6ah0:k, 6ah0:P, 6ahd:P, 6ahd:k, 8ch6:l, 8ch6:4, 7dvq:k, 8h6e:2c, 8h6j:2c, 8h6k:4c, 8h6k:2c, 8h6l:4c, 8h6l:2c, 8i0w:k, 6id0:k, 6id1:k, 5o9z:h, 5o9z:a, 4pjo:R, 7qtt:l, 8qzs:42, 7w59:k, 7w5a:k, 7w5b:k, 5xjc:k, 8y7e:k, 5yzg:k, 5z56:k, 5z57:k, 5z58:k
39 8bif:A 318 52 0.1489 0.0440 0.2692 3.8 8bif:B, 8bif:C, 8bif:D
40 3bg6:A 577 22 0.1064 0.0173 0.4545 4.4 3bg6:B, 3bg6:C, 3bg6:D, 3bg6:E, 3bg6:F, 3bg6:G, 3bg6:H, 3bg7:A, 3bg7:B, 3bg7:C, 3bg7:D, 3bg7:E, 3bg7:F, 3bg7:G, 3bg7:H, 3bly:A, 2f5v:A, 2f6c:A, 3fdy:A, 2igk:A, 2igk:B, 2igk:C, 2igk:D, 2igk:E, 2igk:F, 2igk:G, 2igk:H, 2igm:A, 2igm:B, 2igm:D, 2igm:C, 2igm:E, 2igm:F, 2igm:G, 2igm:H, 2ign:A, 2ign:B, 2ign:D, 2ign:C, 2ign:E, 2ign:F, 2ign:H, 2ign:G, 2igo:A, 2igo:B, 2igo:D, 2igo:C, 2igo:E, 2igo:F, 2igo:H, 2igo:G, 3k4b:A, 3k4c:A, 3k4c:B, 3k4c:C, 3k4c:D, 3k4j:A, 3k4k:A, 3k4l:A, 3k4l:B, 3k4m:A, 3k4m:B, 3k4m:C, 3k4m:D, 3k4m:E, 3k4m:F, 3k4m:G, 3k4m:H, 3k4n:A, 3k4n:B, 3lsh:A, 3lsh:B, 3lsh:C, 3lsh:D, 3lsi:A, 3lsi:B, 3lsk:A, 3lsk:B, 3lsk:C, 3lsk:D, 3lsm:A, 3lsm:B, 4moe:A, 4moe:B, 4moe:C, 4moe:D, 4mof:A, 4mog:A, 4moh:A, 4moi:A, 4moi:B, 4moj:A, 4moj:B, 4moj:C, 4moj:D, 4mok:A, 4mok:B, 4mok:C, 4mok:D, 4mol:A, 4mol:B, 4mol:C, 4mol:D, 4mom:A, 4mom:B, 4mom:C, 4mom:D, 4moo:A, 4mop:A, 4mop:B, 4mop:C, 4mop:D, 4moq:A, 4moq:B, 4mor:A, 4mor:B, 4mor:C, 4mor:D, 4mos:A, 3pl8:A, 1tt0:A, 1tt0:B, 1tt0:C, 1tt0:D, 1tzl:A, 1tzl:B, 1tzl:C, 1tzl:D, 1tzl:E, 1tzl:F, 1tzl:G, 1tzl:H
41 8ro0:d 94 54 0.1383 0.1383 0.2407 5.3 8ro1:d
42 4wzj:KK 104 32 0.1064 0.0962 0.3125 5.7 7abg:h, 7abi:h, 6ahd:c, 7b0y:e, 8c6j:m, 8c6j:a, 7evo:a, 9fmd:k, 9fmd:d, 8h6e:5c, 8h6e:4c, 8h6j:5c, 8h6j:4c, 8h6k:5c, 8h6l:5c, 8hk1:a, 8i0p:c, 8i0p:h, 8i0r:c, 8i0r:h, 8i0s:c, 8i0s:h, 8i0t:h, 8i0u:c, 8i0u:h, 8i0v:c, 8i0v:h, 8i0w:c, 6icz:d, 6id0:d, 6id1:d, 5mqf:h, 5mqf:a, 4pjo:D, 4pjo:d, 4pjo:r, 8q7q:c, 8q7v:c, 8q7w:c, 8q7x:c, 8q91:j, 6qdv:m, 6qdv:j, 8qo9:22, 8qo9:52, 8qo9:42, 6qw6:42, 6qw6:52, 6qx9:12, 6qx9:52, 6qx9:22, 6qx9:42, 8qxd:22, 8qxd:42, 8qxd:52, 8qzs:52, 8qzs:22, 8r08:12, 8r08:42, 8r08:22, 8r08:52, 8r09:22, 8r09:52, 8r09:42, 8r0a:52, 8r0a:42, 8r0a:22, 8r0b:22, 8r0b:42, 8r0b:52, 8rc0:j, 8rm5:22, 8rm5:52, 8rm5:42, 8ro2:d, 7vpx:a, 7vpx:i, 7w59:d, 7w5a:d, 7w5b:d, 4wzj:D, 4wzj:K, 4wzj:R, 4wzj:DD, 4wzj:RR, 4wzj:DDD, 4wzj:KKK, 4wzj:RRR, 4wzj:DDDD, 4wzj:KKKK, 4wzj:RRRR, 5xjc:d, 6y53:h, 6y5q:h, 8y6o:c, 8y6o:j, 5yzg:d, 5z56:d, 5z57:d, 5z58:d
43 6vv5:A 1097 86 0.2766 0.0237 0.3023 8.8 6vv5:B, 6vv5:C
44 6n7p:M 107 65 0.1809 0.1589 0.2615 9.3 7b9v:m, 7b9v:j, 6bk8:a, 7dco:n, 6exn:m, 6exn:j, 6g90:i, 6g90:u, 5gam:j, 5gan:m, 5gan:j, 5gao:m, 5gm6:g, 5gmk:g, 5gmk:e, 6j6g:g, 6j6g:e, 6j6h:g, 6j6h:e, 6j6n:g, 6j6n:e, 6j6q:g, 6j6q:e, 3jcm:Q, 3jcm:U, 5lj3:j, 5lj3:m, 5lj5:j, 5lj5:m, 5mps:j, 5mq0:j, 6n7r:M, 6n7x:M, 5nrl:u, 5nrl:m, 5nrl:i, 7oqb:u, 7oqc:i, 7oqe:i, 7oqe:u, 8w2o:M, 5wsg:g, 5wsg:W, 5y88:g, 5y88:n, 5ylz:g, 5ylz:n, 5zwm:R, 5zwm:c, 5zwm:n, 5zwn:c, 5zwo:c, 5zwo:R, 5zwo:n

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218