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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MLETLKAFFDFGKDIKDDNYSNKLLDILSYLRNNQLYPGESFAHSIKTWFESWKGQFTTVRKSGQCSGCGKTIESIQLSP
EEYECLKGKIMRLKRFENFIKSRPPFDVVIDGLNVAKMFPKVRESQLLLNVVSQLAKRNLRLLVLGRKHMLRRSWSRDEM
EEVQKQASCFFADDISEDDPFLLYATLHSGNHCRFITDAKTQRLFFKWQQGHQLAIFQRILSYDTVVQTTGDSWHIPYDV
PTKWLCLHQ

The query sequence (length=249) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8cbk:E 470 304 0.9960 0.5277 0.8158 2.37e-168 7onu:E
2 4xgl:A 342 282 0.9518 0.6930 0.8404 1.99e-159 4rou:B, 4rou:A, 4xgm:A
3 4g23:A 476 237 0.2088 0.1092 0.2194 3.17e-08 6bv5:A, 6bv6:A, 6bv8:A, 6bv9:A, 4g24:A, 4g25:A, 4g26:A, 6lvr:C, 6lvr:A
4 5diz:A 474 239 0.1687 0.0886 0.1757 0.13 5diz:B, 5ft9:A, 5ft9:B
5 8r42:B 362 56 0.0683 0.0470 0.3036 0.14 8r41:A, 8r41:B, 8r42:A, 8r4x:A, 8r4x:B, 8r4x:C, 8r4x:D
6 2aos:A 361 86 0.0964 0.0665 0.2791 0.22 2fdm:A, 4mav:A, 4ml4:A, 4nsb:A, 2olh:A, 4q7n:A, 5z05:A, 5z3s:A, 5z4w:A, 1zbc:A, 1zbk:A, 1zbv:A, 1zbw:A, 1zl1:A
7 3bh4:A 483 83 0.0803 0.0414 0.2410 0.53 3bh4:B, 1e3x:A, 1e3z:A, 1e40:A, 1e43:A
8 1bli:A 481 44 0.0522 0.0270 0.2955 3.3 1ob0:A, 6toy:A, 6toz:A, 6tp0:A, 6tp1:A, 6tp2:A
9 8xud:D 651 125 0.1165 0.0445 0.2320 7.0 6iqq:C, 6iqq:D, 5wql:D, 5wql:C, 8xud:C
10 8cw4:1B 70 15 0.0361 0.1286 0.6000 7.1 8cw4:2A, 8cw4:2B, 8cw4:1C, 8cw4:2C, 8cw4:1D, 8cw4:1E, 8cw4:2D, 8cw4:1F, 8cw4:2E, 8cw4:2F, 8cw4:1G, 8cw4:2G, 8cw4:1H, 8cw4:2H, 8cw4:1I, 8cw4:2I, 8cw4:1J, 8cw4:2J, 8cw4:1K, 8cw4:2K, 8cw4:1L, 8cw4:2L, 8cw4:1M, 8cw4:1N, 8cw4:2M, 8cw4:2N, 8cw4:3A, 8cw4:3B, 8cw4:3C, 8cw4:3D, 8cw4:3E, 8cw4:3F, 8cw4:3G, 8cw4:3H, 8cw4:3I, 8cw4:3J, 8cw4:3K, 8cw4:3L, 8cw4:3M, 8cw4:3N, 8cw4:4A, 8cw4:4B, 8cw4:4C, 8cw4:4D, 8cw4:4E, 8cw4:4F, 8cw4:4G, 8cw4:4H, 8cw4:4I, 8cw4:4J, 8cw4:4K, 8cw4:4L, 8cw4:4M, 8cw4:4N, 8cw4:5A, 8cw4:5B, 8cw4:5C, 8cw4:5D, 8cw4:5E, 8cw4:5F, 8cw4:5G, 8cw4:5H, 8cw4:5I, 8cw4:5J, 8cw4:5K, 8cw4:5L, 8cw4:5M, 8cw4:5N, 8cw4:1A
11 7jfs:A 958 46 0.0643 0.0167 0.3478 7.7 7jnb:A, 7jnd:A, 7jnf:A, 5kdj:B, 5kdj:A, 5kdn:A, 5kds:A, 5kdu:A
12 4wio:A 525 59 0.0723 0.0343 0.3051 8.0 3uow:A
13 1cxx:A 59 20 0.0361 0.1525 0.4500 8.4 1ibi:A, 1qli:A
14 4yj1:A 600 54 0.0763 0.0317 0.3519 8.8 4yix:A, 4yiy:B, 4yiy:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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