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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MKYILVTGGVISGIGKGIIASSVGTILKSCGLHVTSIKIDPYINIDAGTFSPYEHGEVFVLDDGGEVDLDLGNYERFLDI
RLTKDNNLTTGKIYQYVINKERKGDYLGKTVQVVPHITDAIQEWVMRQALIPVDEDGLEPQVCVIELGGTVGDIESMPFI
EAFRQFQFKVKRENFCNIHVSLVPQPSSTGEQKTKPTQNSVRELRGLGLSPDLVVCRCSNPLDTSVKEKISMFCHVEPEQ
VICVHDVSSIYRVPLLLEEQGVVDYFLRRLDLPKMLMKWKEMADRYDRLLETCSIALVGKYTKFSDSYASVIKALEHSAL
AINHKLEIKYIDSADLEPITSQEEPVRYHEAWQKLCSAHGVLVPGGFGVRGTEGKIQAIAWARNQKKPFLGVCLGMQLAV
VEFSRNVLGWQDANSTEFDPTTSHPVVVDMPEHNMRLGKRRTLFQTKNSVMRKLYGDADYLEERHRHRFEVNPVWKKCLE
EQGLKFVGQDVEGERMEIVELEDHPFFVGVQYHPEFLSRPIKPSPPYFGLLLASVGRLSHYL

The query sequence (length=542) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5u03:A 559 555 1.0000 0.9696 0.9766 0.0 7mgz:F, 7mgz:P, 7mgz:O, 7mgz:Q, 7mh0:A, 7mh0:B, 7mh0:C, 7mh0:D, 7mif:C, 7mif:G, 7mif:H, 7mif:I, 7mig:C, 7mig:A, 7mig:B, 7mig:E, 7mip:C, 7mip:D, 7mip:G, 7mip:I, 5u03:B, 5u03:C, 5u03:D
2 6pk4:A 559 555 0.7731 0.7496 0.7550 0.0 7mh1:H, 7mh1:J, 7mh1:K, 7mh1:L, 7miu:D, 7miu:C, 7miu:H, 7miu:G, 7miv:D, 7miv:C, 7miv:H, 7miv:G, 6pk4:B, 6pk4:C, 6pk4:D, 6pk7:A, 6pk7:D, 6pk7:E, 6pk7:F
3 7mii:A 497 542 0.7232 0.7887 0.7232 0.0 7mih:A, 7mih:B, 7mih:C, 7mih:E, 7mii:B, 7mii:C, 7mii:E
4 7dpt:A 556 556 0.6790 0.6619 0.6619 0.0 7dpt:B, 7dpt:C, 7dpt:D, 7dpw:A, 7dpw:B, 7dpw:C, 7dpw:D, 8i0h:A, 8i0i:A, 8i0i:C, 8i0i:D, 8i0i:E, 7wiz:A, 7wiz:B, 7wiz:C, 7wiz:D, 7wj4:D, 7wj4:A, 7wj4:B, 7wj4:C
5 7rmc:V 561 555 0.6015 0.5811 0.5874 0.0 7rmc:D, 7rmc:F, 7rmc:E, 7rmc:g, 7rmc:Q, 7rmc:U, 7rmc:S, 7rmc:h, 7rmc:R, 7rmc:W, 7rmc:T, 7rmk:R, 7rmk:K, 7rmk:L, 7rmk:M, 7rmk:Y, 7rmk:I, 7rmk:P, 7rmk:U, 7rmk:D, 7rmk:A, 7rmk:B, 7rmk:C, 7rmk:Z, 7rmk:J, 7rmk:Q, 7rmk:V, 7rmk:H, 7rmk:E, 7rmk:F, 7rmk:G, 7rmk:a, 7rmk:N, 7rmk:S, 7rmk:W, 7rmk:b, 7rmk:O, 7rmk:T, 7rmk:X, 7rmo:D, 7rmo:A, 7rmo:B, 7rmo:C, 7rmo:U, 7rmo:I, 7rmo:M, 7rmo:Q, 7rmo:V, 7rmo:J, 7rmo:N, 7rmo:R, 7rmo:H, 7rmo:E, 7rmo:F, 7rmo:G, 7rmo:W, 7rmo:K, 7rmo:O, 7rmo:S, 7rmo:b, 7rmo:Y, 7rmo:Z, 7rmo:a, 7rmo:X, 7rmo:L, 7rmo:P, 7rmo:T, 7rmv:B, 7rmv:A, 7rmv:D, 7rmv:C, 7rmv:F, 7rmv:E, 7rmv:H, 7rmv:G
6 7rkh:D 559 554 0.5793 0.5617 0.5668 0.0 7rkh:C, 7rkh:A, 7rkh:B, 7rl0:A, 7rl0:D, 7rl0:B, 7rl0:C, 7rl0:E, 7rl0:H, 7rl0:F, 7rl0:G, 7rl0:W, 7rl0:Z, 7rl0:X, 7rl0:Y, 7rl5:A, 7rl5:B, 7rl5:D, 7rl5:C, 7rl5:E, 7rl5:M, 7rl5:R, 7rl5:P, 7rl5:L, 7rl5:O, 7rl5:S, 7rl5:Q, 7rnl:B, 7rnl:C, 7rnl:D, 7rnl:A, 7rnl:H, 7rnl:K, 7rnl:N, 7rnl:E, 7rnl:I, 7rnl:L, 7rnl:O, 7rnl:F, 7rnl:J, 7rnl:M, 7rnl:P, 7rnl:G, 7rnr:A, 7rnr:B, 7rnr:F, 7rnr:E, 7rnr:Q, 7rnr:S, 7rnr:a, 7rnr:Y, 7rnr:I, 7rnr:J, 7rnr:N, 7rnr:M, 7rnr:R, 7rnr:T, 7rnr:b, 7rnr:Z, 7rnr:g, 7rnr:h, 7rnr:l, 7rnr:k
7 1vco:A 531 552 0.4815 0.4915 0.4728 4.90e-166 1vcn:A
8 4zdj:A 535 539 0.4557 0.4617 0.4583 2.75e-160 4zdk:A, 4zdk:B
9 2vo1:A 235 273 0.4299 0.9915 0.8535 1.19e-159
10 8fve:B 538 547 0.4446 0.4480 0.4406 7.28e-155 2ad5:A, 2ad5:B, 8fv6:AAA, 8fv6:BBB, 8fv7:AAA, 8fv7:BBB, 8fv8:AAA, 8fv8:BBB, 8fv9:AAA, 8fv9:BBB, 8fva:AAA, 8fva:BBB, 8fvb:AAA, 8fvb:BBB, 8fvc:AAA, 8fvc:BBB, 8fvd:A, 8fvd:B, 8fve:A, 8i9o:A, 8i9o:B, 8i9o:D, 8i9o:C, 1s1m:A, 1s1m:B, 8sbr:A, 8sbr:B, 5tkv:A, 5tkv:B, 5u3c:A, 5u3c:B, 5u3c:C, 5u3c:D, 5u6r:A, 5u6r:B, 5u6r:C, 5u6r:D
11 3ihl:A 233 273 0.3579 0.8326 0.7106 1.54e-135 3ihl:B
12 5n29:A 265 257 0.1919 0.3925 0.4047 3.51e-55
13 6vtv:B 252 55 0.0369 0.0794 0.3636 0.12 6vtv:A
14 6pij:A 351 124 0.0590 0.0912 0.2581 1.5 8fuk:A, 8fuk:B, 8fuk:C, 8fuk:D, 8fuk:E, 6lnb:G, 6lnb:F, 6lnb:E, 6lnb:D, 6lnb:C, 6lnc:G, 6lnc:F, 6lnc:E, 6lnc:D, 6lnc:C, 6pif:A, 6pif:B, 6pif:C, 6pif:D, 6pif:E, 6pig:A, 6pig:B, 6pig:C, 6pig:D, 6pig:E, 6pij:B, 6pij:C, 6pij:D, 6pij:E, 6uvn:G, 6uvn:F, 6uvn:E, 6uvn:H, 6uvn:D, 6v9q:B, 6v9q:C, 6v9q:D, 6v9q:E, 6v9q:F, 6vbw:B, 6vbw:C, 6vbw:D, 6vbw:F, 6vbw:E
15 7yc6:A 183 81 0.0424 0.1257 0.2840 1.6
16 3s27:H 797 140 0.0609 0.0414 0.2357 4.0 3s27:A, 3s27:B, 3s27:C, 3s27:D, 3s27:E, 3s27:F, 3s27:G, 3s28:A, 3s28:B, 3s28:C, 3s28:D, 3s28:E, 3s28:F, 3s28:G, 3s28:H, 3s29:A, 3s29:B, 3s29:C, 3s29:D, 3s29:E, 3s29:F, 3s29:G, 3s29:H
17 6ox1:B 484 62 0.0332 0.0372 0.2903 4.9 6ict:A, 6ict:B, 6ict:C, 6ict:D, 6icv:A, 6icv:B, 6jat:A, 6jat:C, 7lms:A, 6mbj:A, 6mbj:B, 6mbk:A, 6mbk:B, 6mbl:A, 6ox0:A, 6ox0:B, 6ox1:A, 6ox2:A, 6ox2:B, 6ox3:A, 6ox3:B, 6ox4:A, 6ox4:B, 6ox5:A, 3smt:A, 6v62:A, 6v63:A, 6v63:B, 7w28:A, 7w29:A, 6wk1:A, 6wk1:B, 6wk2:A, 6wk2:D, 8x77:B
18 3fij:A 224 146 0.0627 0.1518 0.2329 5.4 3fij:B, 3fij:C, 3fij:D, 3fij:E, 3fij:F, 3fij:G, 3fij:H
19 4evi:A 360 79 0.0369 0.0556 0.2532 5.5 4e70:A, 4e70:B, 4evi:B
20 4fgm:A 587 186 0.0812 0.0750 0.2366 6.3
21 6c0d:A 404 123 0.0480 0.0644 0.2114 6.4
22 1xoc:A 504 117 0.0480 0.0516 0.2222 6.8
23 6rop:B 831 31 0.0203 0.0132 0.3548 7.2
24 5my0:A 852 31 0.0203 0.0129 0.3548 7.6 5my0:C, 5my0:D, 5my2:D, 6rop:A, 6rop:C, 6rop:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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