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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MKIKTRFAPSPTGYLHVGGARTALYSWLFARNHGGEFVLRIEDTDLERSTPEAIEAIMDGMNWLSLEWDEGPYYQTKRFD
RYNAVIDQMLEEGTAYKCYCSKERLEALREEQMAKGEKPRYDGRCRHSHEHHADDEPCVVRFANPQEGSVVFDDQIRGPI
EFSNQELDDLIIRRTDGSPTYNFCVVVDDWDMEITHVIRGEDHINNTPRQINILKALKAPVPVYAHVSMINGDDGEKLSK
RHGAVSVMQYRDDGYLPEALLNYLVRLGWSHGDQEIFTREEMIKYFTLNAVSKSASAFNTDKLLWLNHHYINALPPEYVA
THLQWHIAQENIDTRNGPQLADLVKLLGERCKTLKEMAQSCRYFYEDFAEFDADAAKKHLRPVARQPLEVVRDKLAAITD
WTAENVHHAIQATADELEVGMGKVGMPLRVAVTGAGQSPALDVTVHAIGKTRSIERINKALDFIAERE

The query sequence (length=468) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8i9i:A 468 468 1.0000 1.0000 1.0000 0.0 8i9i:B
2 4g6z:A 380 370 0.4103 0.5053 0.5189 5.51e-135
3 2cfo:A 484 455 0.4167 0.4029 0.4286 4.76e-113
4 4gri:B 485 488 0.3675 0.3546 0.3525 7.78e-102 4gri:A
5 3al0:C 564 473 0.3632 0.3014 0.3594 1.12e-97 3afh:A, 3akz:B, 3akz:D, 3akz:C, 3akz:A
6 8vc5:A 488 480 0.3868 0.3709 0.3771 1.59e-96 8vc5:B
7 6brl:A 502 500 0.3654 0.3406 0.3420 8.07e-96
8 2cuz:A 468 478 0.3611 0.3611 0.3536 4.90e-91 2cv0:A, 2cv0:B, 2cv1:A, 2cv1:B, 2cv2:A, 2cv2:B, 2dxi:A, 2dxi:B, 1g59:A, 1g59:C, 1j09:A, 1n75:A, 1n77:A, 1n77:B, 1n78:A, 1n78:B
9 4a91:A 290 301 0.2201 0.3552 0.3422 1.07e-39 1nzj:A
10 3aii:A 455 289 0.1709 0.1758 0.2768 4.27e-22
11 4h3s:A 585 127 0.0897 0.0718 0.3307 6.50e-16
12 4jyz:A 542 122 0.0748 0.0646 0.2869 5.47e-13 1euq:A, 1euy:A, 1exd:A, 1gtr:A, 1gts:A, 4jxx:A, 4jxz:A, 1o0b:A, 1o0c:A, 1qrs:A, 1qrt:A, 1qru:A, 1qtq:A, 2rd2:A, 2re8:A, 1zjw:A
13 5zdk:A 543 124 0.0855 0.0737 0.3226 2.34e-10 5zdl:A
14 8uk6:A 573 109 0.0662 0.0541 0.2844 5.30e-10
15 7wao:A 502 338 0.1560 0.1454 0.2160 1.75e-08 7waj:A, 7wak:A, 7wal:A
16 6euf:A 472 85 0.0556 0.0551 0.3059 0.51 6euf:B, 6euf:C, 6euf:D
17 5dul:C 367 105 0.0598 0.0763 0.2667 1.6
18 3t3o:A 553 88 0.0449 0.0380 0.2386 4.9 3bk1:A, 3bk2:A, 3t3n:A
19 7e38:A 313 42 0.0342 0.0511 0.3810 7.1 8ci9:C, 7e37:A, 7e37:B, 7e38:B
20 3j0a:B 632 22 0.0256 0.0190 0.5455 7.3
21 5dul:B 390 107 0.0577 0.0692 0.2523 9.8 5dul:A, 5dul:D, 3iie:A, 3iie:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218