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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MKAAAKRISDGVYWTGVLDWDLRNYHGYTLQGTTYNAYLVCGDEGVALIDNSYPGTFDELMARVEDALQQVGMERVDYII
QNHVEKDHSGVLVELHRRFPEAPIYCTEVAVKGLLKHYPSLREAEFMTVKTGDVLDLGGKTLTFLETPLLHWPDSMFTLL
DEDGILFSNDAFGQHLCCPQRLDREIPEYILMDAARKFYANLITPLSKLVLKKFDEVKELGLLERIQMIAPSHGQIWTDP
MKIIEAYTGWATGMVDERVTVIYDTMHGSTRKMAHAIAEGAMSEGVDVRVYCLHEDDRSEIVKDILESGAIALGAPTIYD
EPYPSVGDLLMYLRGLKFNRTLTRKALVFGSMGGNGGATGTMKELLAEAGFDVACEEEVYYVPTGDELDACFEAGRKLAA
EIR

The query sequence (length=403) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 2ohh:A 403 403 1.0000 1.0000 1.0000 0.0 2ohh:B, 2ohh:D, 2ohh:E, 2ohi:A, 2ohi:B, 2ohi:D, 2ohi:E, 2ohi:G, 2ohi:H, 2ohi:I, 2ohi:J, 2ohj:A, 2ohj:B, 2ohj:D, 2ohj:E
2 6zk8:A 410 405 0.7072 0.6951 0.7037 0.0 6frm:A, 6frm:B, 6frm:C, 6frm:D, 6frm:E, 6frm:H, 6frm:F, 6frm:G, 6frn:A, 6frn:B, 6frn:C, 6frn:D, 6zk8:O, 6zlf:A, 6zlf:F, 6zlf:G, 6zlf:H, 6zlf:I, 6zlf:J, 6zlf:K, 6zlf:L
3 1ycf:A 398 401 0.4144 0.4196 0.4165 8.82e-107 1ycf:B, 1ycf:C, 1ycf:D, 1ycg:A, 1ycg:B, 1ycg:C, 1ycg:D, 1ych:A, 1ych:B, 1ych:C, 1ych:D
4 7r0f:A 401 403 0.3821 0.3840 0.3821 4.96e-96 4d02:A, 6etb:A, 6etb:B, 5lld:A, 5lmc:A, 7r0f:B, 7r1h:A, 7r1h:B, 7r1j:A, 7r1j:B, 7r2o:A, 7r2o:B, 7r2p:A, 7r2p:B, 7r2r:A, 7r2r:B, 7r2s:A, 7r2s:B
5 1e5d:A 401 386 0.3226 0.3242 0.3368 6.87e-66 1e5d:B
6 2q9u:A 409 375 0.3077 0.3032 0.3307 1.26e-58 2q9u:B
7 4dik:A 402 361 0.2705 0.2711 0.3019 3.91e-32 4dik:B, 4dil:A, 4dil:B, 5v8s:A, 5v8s:B, 1vme:A, 1vme:B
8 4ad9:A 288 150 0.1166 0.1632 0.3133 3.84e-07 4ad9:B, 4ad9:C, 4ad9:D, 4ad9:E, 4ad9:F
9 5wid:A 144 154 0.1092 0.3056 0.2857 9.22e-06 5wid:B, 5wid:C
10 2fax:A 138 144 0.0993 0.2899 0.2778 6.25e-04 2fdx:A, 1fla:A, 1fld:A, 1fln:A, 2flv:A, 2fox:A, 1fvx:A, 2fvx:A, 3nll:A, 4nll:A, 5nll:A, 4nul:A, 5nul:A, 6nul:A, 5ull:A
11 4awy:B 270 127 0.0819 0.1222 0.2598 0.002 4awz:A, 4awz:B, 4awz:C, 4ax0:B, 4ax1:B, 4p62:A
12 6qwo:B 253 213 0.1489 0.2372 0.2817 0.005 6qwo:A
13 6c2c:A 299 73 0.0571 0.0769 0.3151 0.009 6c2c:B, 5hif:A, 5hif:B
14 3adr:A 259 171 0.0968 0.1506 0.2281 0.043 3adr:B
15 4xuk:A 291 92 0.0670 0.0928 0.2935 0.044 4xuk:B
16 2a5l:B 175 64 0.0471 0.1086 0.2969 0.049 2a5l:A, 1zwl:A
17 1p9e:A 294 73 0.0571 0.0782 0.3151 0.065 1p9e:B
18 4le6:A 257 64 0.0496 0.0778 0.3125 0.14 4le6:B, 4le6:C, 4le6:D, 4le6:E
19 7q6n:D 204 117 0.0819 0.1618 0.2821 0.14 3b6i:A, 3b6i:B, 3b6j:A, 3b6j:B, 3b6k:A, 3b6k:B, 3b6m:A, 3b6m:B, 4dy4:A, 4dy4:C, 5f12:A, 5f12:B, 7q6n:A, 7q6n:B, 7q6n:C, 2r96:A, 2r96:C, 2r97:A, 2r97:C, 4yqe:A, 4yqe:B, 3zho:A, 3zho:B
20 2fz5:A 137 146 0.0968 0.2847 0.2671 0.15
21 4o98:B 307 64 0.0496 0.0651 0.3125 0.16 4o98:A
22 7y7u:A 288 78 0.0620 0.0868 0.3205 0.16 7y7u:B
23 5t79:A 315 199 0.1216 0.1556 0.2462 0.28 3erp:A, 3erp:B
24 5ngg:A 274 124 0.0819 0.1204 0.2661 0.44 2gmn:A, 2gmn:B, 3lvz:A, 3lvz:B, 5ngg:B, 5njw:A, 5njw:B, 5wcm:A, 5wcm:B
25 2xr1:B 611 72 0.0496 0.0327 0.2778 0.57 2xr1:A
26 6r9n:A 233 204 0.1166 0.2017 0.2304 0.70 6r9n:B
27 2bib:A 540 51 0.0347 0.0259 0.2745 0.81 1wra:A, 1wra:B
28 3b9o:A 433 43 0.0447 0.0416 0.4186 1.7 3b9o:B
29 3wqy:A 905 50 0.0347 0.0155 0.2800 2.8 3wqy:B, 3wqz:A, 3wqz:B, 2ztg:A
30 3dev:A 316 57 0.0521 0.0665 0.3684 3.3 3dev:B
31 5t99:A 757 60 0.0447 0.0238 0.3000 3.7 5t99:B
32 2ycb:B 635 35 0.0323 0.0205 0.3714 4.8 2ycb:A
33 3dha:A 254 75 0.0596 0.0945 0.3200 5.7 2a7m:A, 2br6:A, 2btn:A, 3dhb:A, 3dhc:A, 5eh9:A, 5eht:A, 4j5f:A, 4j5h:A, 7l5f:A
34 6uxu:A 300 173 0.0943 0.1267 0.2197 5.9 6uxu:B
35 6evj:B 752 117 0.0819 0.0439 0.2821 6.9 6evj:E, 6evk:B, 9f2r:B, 9f37:B, 6fhh:B, 6fhi:B, 5m3h:B, 6szu:B, 6szv:B, 6t0n:B, 6t0r:B, 6t0s:B, 6t0u:B, 6t0v:B, 6t2c:B, 6tw1:B, 4wsb:B
36 3gqt:C 385 79 0.0571 0.0597 0.2911 8.5 3d6b:C, 3eon:C, 3gnc:A, 3gnc:B, 3gnc:C, 3gnc:D, 3gqt:A, 3gqt:B
37 1uef:A 105 59 0.0521 0.2000 0.3559 8.5 1uef:B
38 3ab8:A 261 34 0.0347 0.0536 0.4118 8.9 3ab8:B
39 7w9y:A 389 116 0.0769 0.0797 0.2672 9.3 7w9y:B, 7w9y:C, 7w9y:D, 7w9z:A, 7w9z:B
40 3e4d:A 278 92 0.0645 0.0935 0.2826 9.6 3e4d:B, 3e4d:C, 3e4d:E, 3e4d:D, 3e4d:F
41 8i9w:CL 397 67 0.0496 0.0504 0.2985 9.7 8i9t:CL, 8i9v:CL, 8i9x:CL, 8i9y:CL, 8i9z:CL, 8ia0:CL, 8pv1:CL, 8pv2:CL, 8pv3:CL, 8pv4:CL, 8pv5:CL, 8pv6:CL, 8pv7:CL, 8pv8:CL, 8pvk:CL, 8pvl:CL

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218