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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MFTEEEEEEFLQLSRNPKLYEILTNSIAPSIFGNEDIKKAIVCLLMGGSKKILPDGMRLRGDINVLLLAKSQLLKFVEKV
SPIAVYTSGKGAAGLTASVQRFYLEGGAMVLADGGVVCIDEFDKMRDEDRVAIHEAMEQQTISIAKAGITTVLNSRTSVL
AAANTTILSRFDMIFIVNEERDISIANHVINIHTSEISIEKMKRYITYCRLKCAPRLSPQAAEKLSSNFVTIRKQLLINP
ITIRQLEAIIRITESLAKLELSPIAQERHVDEAIRLFQAS

The query sequence (length=280) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8b9a:5 533 288 0.9964 0.5235 0.9688 0.0 8b9b:5, 8b9c:5, 6sko:5
2 8w7m:5 529 285 0.9357 0.4953 0.9193 1.23e-179
3 5bk4:D 661 340 1.0000 0.4236 0.8235 1.46e-176 5bk4:5
4 8p5e:5 695 340 1.0000 0.4029 0.8235 9.50e-176 6eyc:5, 6f0l:D, 6f0l:5, 3ja8:5, 8kg6:5, 8kg8:5, 8kg9:5, 7p30:5, 7p30:D, 7p5z:5, 7p5z:D, 8p62:5, 8p63:5, 7pmk:5, 6ptn:l, 6ptn:5, 6pto:k, 6pto:5, 7pt6:5, 7pt6:E, 7pt7:5, 7pt7:E, 7qhs:5, 6rqc:5, 6skl:5, 6u0m:5, 5u8s:5, 5u8t:5, 7v3u:5, 7v3u:E, 7v3v:5, 7v3v:E, 7w8g:5, 7w8g:E, 8xgc:5, 7z13:5, 7z13:d
5 7pmn:5 660 339 0.9964 0.4227 0.8230 2.18e-175
6 6hv9:5 628 323 0.9643 0.4299 0.8359 2.17e-173
7 8q6p:5 321 311 0.6929 0.6044 0.6238 3.47e-131
8 6xtx:5 577 305 0.6857 0.3328 0.6295 8.87e-123 6xty:5
9 7pfo:5 605 333 0.7000 0.3240 0.5886 1.53e-122 8b9d:5
10 7w1y:5 710 328 0.7000 0.2761 0.5976 4.87e-122 7plo:5, 7w1y:D
11 6raw:5 576 328 0.6893 0.3351 0.5884 4.77e-115
12 6rax:5 620 333 0.6964 0.3145 0.5856 8.48e-115 6ray:5, 6raz:5
13 8ouw:5 541 301 0.6000 0.3105 0.5581 7.05e-102
14 4fdg:B 592 325 0.5107 0.2416 0.4400 4.64e-79 8eaf:A, 8eaf:B, 8eaf:C, 8eaf:D, 8eaf:E, 8eaf:F, 8eag:B, 8eag:C, 8eag:D, 8eag:E, 8eag:F, 8eag:A, 8eah:A, 8eah:B, 8eah:C, 8eah:D, 8eah:E, 8eah:F, 8eai:B, 8eai:C, 8eai:D, 8eai:E, 8eai:F, 8eai:A, 8eaj:A, 8eaj:B, 8eaj:C, 8eaj:D, 8eaj:E, 8eaj:F, 8eak:B, 8eak:C, 8eak:D, 8eak:E, 8eak:A, 8eak:F, 8eal:A, 8eal:B, 8eal:C, 8eal:D, 8eal:E, 8eal:F, 8eam:B, 8eam:C, 8eam:D, 8eam:E, 8eam:A, 8eam:F, 4fdg:A, 4fdg:C, 4fdg:D, 4fdg:E, 6mii:A, 6mii:B, 6mii:C, 6mii:D, 6mii:E, 6mii:F, 2vl6:A, 2vl6:B, 2vl6:C, 6wnz:B, 6wnz:A
15 4r7y:A 591 321 0.5000 0.2369 0.4361 5.34e-76 4r7y:B, 4r7z:A, 4r7z:B, 4r7z:C, 4r7z:D, 4r7z:E, 4r7z:F, 4r7z:G, 4r7z:H, 4r7z:I, 4r7z:P, 4r7z:J, 4r7z:K, 4r7z:L, 4r7z:M, 4r7z:N, 4r7z:O
16 5u8t:2 583 316 0.5036 0.2419 0.4462 1.73e-75
17 8q6p:6 395 318 0.4786 0.3392 0.4214 2.80e-74
18 7pt6:2 629 321 0.5036 0.2242 0.4393 4.28e-74 5bk4:2, 5bk4:A, 6eyc:2, 6f0l:A, 6f0l:2, 3ja8:2, 7p30:2, 7p30:A, 7p5z:2, 7p5z:A, 7pt6:B, 7pt7:2, 7pt7:B, 6rqc:2, 6sko:2, 5u8s:2, 7v3u:2, 7v3u:B, 7v3v:2, 7v3v:B, 5v8f:2, 8w7m:2, 7w8g:2, 7w8g:B
19 8x7u:D 654 328 0.4964 0.2125 0.4238 1.02e-72 8x7u:E, 8x7u:C, 8x7u:B, 8x7u:F, 8x7u:A
20 6raw:6 601 321 0.5036 0.2346 0.4393 1.74e-72 6raz:6
21 6hv9:3 558 285 0.4679 0.2348 0.4596 4.24e-72
22 5v8f:3 654 300 0.4750 0.2034 0.4433 3.78e-71 5bk4:B, 5bk4:3, 6eyc:3, 6f0l:3, 6f0l:B, 3ja8:3, 7p30:3, 7p30:B, 7p5z:3, 7p5z:B, 6ptn:j, 6ptn:3, 6pto:i, 6pto:3, 6rqc:3, 6sko:3, 6u0m:3, 5u8s:3, 5u8t:3
23 6rax:6 628 327 0.5000 0.2229 0.4281 7.85e-71 6ray:6
24 8xgc:2 778 338 0.5036 0.1812 0.4172 3.17e-70 8kg6:2, 8kg8:2, 8kg9:2, 8p5e:2, 8p62:2, 8p63:2, 7pmk:2, 7pmn:2, 6ptn:i, 6ptn:2, 6pto:h, 6pto:2, 7qhs:2, 6skl:2, 6u0m:2, 7z13:2, 7z13:a
25 6wgi:3 637 299 0.4714 0.2072 0.4415 6.08e-70
26 6hv9:2 549 294 0.4679 0.2386 0.4456 6.18e-70
27 8w7m:3 619 310 0.4750 0.2149 0.4290 1.03e-69 8b9a:3, 8b9b:3, 8b9c:3, 7pmk:3, 6skl:3, 8xgc:3
28 6xtx:6 679 327 0.4750 0.1959 0.4067 6.17e-69 8b9d:6, 7pfo:6, 7plo:6, 6xty:6
29 7w1y:6 716 327 0.4750 0.1858 0.4067 1.05e-68 7w1y:E
30 8ouw:3 619 330 0.4893 0.2213 0.4152 2.50e-68
31 8b9d:7 576 306 0.4679 0.2274 0.4281 1.17e-66
32 7pt7:C 633 331 0.4750 0.2101 0.4018 2.04e-66
33 6skl:4 679 293 0.4536 0.1870 0.4334 2.11e-66 8kg9:4, 8xgc:4
34 8q6p:3 370 339 0.4750 0.3595 0.3923 2.20e-66
35 8ouw:4 619 319 0.4571 0.2068 0.4013 4.35e-66
36 8ouw:7 632 316 0.4607 0.2041 0.4082 8.76e-65
37 8kg8:4 697 318 0.4607 0.1851 0.4057 1.38e-64 8b9a:4, 8b9b:4, 8b9c:4, 8kg6:4, 8p5e:4, 8p62:4, 8p63:4, 7pmk:4, 7pmn:4, 7qhs:4, 6sko:4, 8w7m:4, 7z13:4, 7z13:c
38 8p5e:3 649 343 0.4821 0.2080 0.3936 1.69e-64 8kg6:3, 8kg8:3, 8kg9:3, 8p62:3, 8p63:3, 7pt6:3, 7pt6:C, 7pt7:3, 7qhs:3, 7v3u:3, 7v3u:C, 7v3v:3, 7v3v:C, 7w8g:3, 7w8g:C, 7z13:3, 7z13:b
39 5v8f:4 741 315 0.4643 0.1754 0.4127 2.14e-64 5bk4:C, 5bk4:4, 6eyc:4, 6f0l:C, 3ja8:4, 7p30:4, 7p30:C, 7p5z:C, 7p5z:4, 7pt6:4, 7pt6:D, 7pt7:4, 7pt7:D, 6rqc:4, 7v3u:4, 7v3u:D, 7v3v:4, 7v3v:D, 7w8g:4, 7w8g:D
40 5u8t:6 661 303 0.4464 0.1891 0.4125 2.65e-64 6wgi:6
41 5v8f:6 692 306 0.4464 0.1806 0.4085 3.43e-64 8b9a:6, 8b9b:6, 8b9c:6, 6eyc:6, 3ja8:6, 8kg6:6, 8kg8:6, 8kg9:6, 7p30:6, 7p30:E, 7p5z:6, 7p5z:E, 8p5e:6, 8p62:6, 8p63:6, 7pmk:6, 7pmn:6, 6ptn:m, 6ptn:6, 6pto:l, 6pto:6, 7pt6:6, 7pt6:F, 7pt7:6, 7pt7:F, 6rqc:6, 6skl:6, 6sko:6, 6u0m:6, 5u8s:6, 8w7m:6, 8xgc:6
42 7v3u:6 646 306 0.4464 0.1935 0.4085 3.71e-64 7qhs:6, 7v3u:F, 7v3v:6, 7v3v:F, 7w8g:6, 7w8g:F, 7z13:6, 7z13:e
43 6rax:2 605 314 0.4357 0.2017 0.3885 2.20e-63 6raw:2, 6ray:2
44 8b9d:2 576 322 0.4571 0.2222 0.3975 2.27e-63
45 6xtx:7 598 322 0.4607 0.2157 0.4006 4.89e-63 6xty:7
46 6raz:2 559 300 0.4250 0.2129 0.3967 5.73e-63
47 7plo:7 607 324 0.4643 0.2142 0.4012 6.19e-63 7pfo:7
48 7w1y:F 643 322 0.4607 0.2006 0.4006 1.44e-62 7w1y:7
49 6xtx:3 608 308 0.4500 0.2072 0.4091 2.49e-62
50 7w1y:2 706 324 0.4607 0.1827 0.3981 3.14e-62 7pfo:2, 7plo:2, 8q6o:A, 8q6o:2, 8q6p:2, 7w1y:A, 6xtx:2, 6xty:2
51 7w1y:4 653 321 0.4714 0.2021 0.4112 4.90e-62 7w1y:C, 6xtx:4, 6xty:4
52 6ray:3 600 332 0.4786 0.2233 0.4036 5.26e-62 6raw:3, 6raz:3
53 8b9d:3 569 322 0.4500 0.2214 0.3913 9.29e-61
54 8b9d:4 677 321 0.4786 0.1979 0.4174 4.08e-60 7pfo:4, 7plo:4
55 7v3u:7 699 332 0.4893 0.1960 0.4127 5.04e-60 5bk4:F, 5bk4:7, 6eyc:7, 3ja8:7, 7p30:7, 7p30:F, 7p5z:7, 7p5z:F, 7v3u:G, 7v3v:7, 7v3v:G, 7w8g:7, 7w8g:G
56 6rax:3 625 350 0.4857 0.2176 0.3886 8.35e-60
57 5v8f:7 725 332 0.4893 0.1890 0.4127 8.84e-60 8b9a:7, 8b9b:7, 8b9c:7, 3jc6:7, 3jc7:7, 8kg6:7, 8kg8:7, 8p5e:7, 8p62:7, 8p63:7, 7pt6:7, 7pt6:G, 7pt7:7, 7pt7:G, 7qhs:7, 6rqc:7, 6sko:7, 8w7m:7, 7z13:7, 7z13:f
58 6rax:4 626 324 0.4821 0.2157 0.4167 3.69e-59 6raw:4, 6ray:4, 6raz:4
59 7plo:3 628 344 0.4571 0.2038 0.3721 1.33e-57 7pfo:3
60 8b9a:2 568 322 0.4464 0.2201 0.3882 2.08e-57 8b9b:2, 8b9c:2
61 8ouw:6 707 329 0.4750 0.1881 0.4043 3.87e-57
62 6raz:7 601 322 0.4536 0.2113 0.3944 2.79e-56 6ray:7
63 8ouw:2 701 321 0.4393 0.1755 0.3832 4.22e-56
64 6rax:7 632 311 0.4429 0.1962 0.3987 1.10e-55 6raw:7
65 7w1y:B 651 355 0.4500 0.1935 0.3549 2.02e-55 7w1y:3
66 8q6p:7 298 315 0.4214 0.3960 0.3746 8.75e-55
67 8kg9:7 636 319 0.4714 0.2075 0.4138 2.05e-53 7pmk:7, 7pmn:7, 6skl:7, 8xgc:7
68 8s91:A 602 311 0.4036 0.1877 0.3633 5.40e-47 7dp3:A, 8s91:B, 8s91:C, 8s94:A, 8s94:C, 8s94:B
69 7wi7:A 565 291 0.3750 0.1858 0.3608 3.92e-44
70 7wi7:B 566 280 0.3607 0.1784 0.3607 1.26e-43
71 8s91:D 621 295 0.3750 0.1691 0.3559 1.27e-42 7dpd:A, 7dpd:B, 8s91:E, 8s91:F, 8s94:D, 8s94:F, 8s94:E
72 7sgr:E 700 48 0.0536 0.0214 0.3125 0.64 3b5j:A, 8dck:A, 8dck:B, 8dck:I, 8dck:J, 8dck:E, 8dck:F, 2ff7:A, 2ffa:A, 2ffb:A, 2fgj:A, 2fgj:B, 2fgj:C, 2fgj:D, 2fgk:A, 2fgk:B, 2fgk:C, 2fgk:D, 2pmk:A, 7sgr:J, 7sgr:A, 7sgr:F, 1xef:A, 1xef:B, 1xef:C, 1xef:D
73 4xru:D 287 90 0.0857 0.0836 0.2667 1.1
74 3was:A 389 89 0.0821 0.0591 0.2584 1.9 4kmi:A, 4kmi:B, 3was:B, 3wat:A, 3wat:B, 3wau:A, 3wau:B
75 5cq9:B 270 56 0.0571 0.0593 0.2857 5.1
76 5xla:A 490 142 0.1107 0.0633 0.2183 7.6 3eyk:B, 5xl3:B, 5xl3:A, 5xl4:A, 5xl4:B, 5xl6:A, 5xl7:A, 5xl7:B, 5xl9:A, 5xla:B, 5xlc:A, 5xlc:B, 5xld:A, 5xld:B
77 7krw:A 608 73 0.0679 0.0312 0.2603 9.6 4b9q:A, 4b9q:B, 4b9q:C, 4b9q:D, 1dkx:A, 1dky:A, 1dky:B, 1dkz:A, 3dpo:B, 3dpo:A, 3dpp:A, 3dpp:B, 3dpq:B, 3dpq:A, 3dpq:F, 3dpq:E, 4e81:A, 4e81:B, 4ezn:A, 4ezn:B, 4ezo:A, 4ezo:B, 4ezp:A, 4ezp:B, 4ezq:A, 4ezr:A, 4ezs:A, 4ezt:A, 4ezu:A, 4ezv:A, 4ezv:B, 4ezw:A, 4ezw:B, 4ezw:C, 4ezw:D, 4ezx:A, 4ezx:B, 4ezy:A, 4ezz:A, 4f00:A, 4hy9:A, 4hy9:B, 4hyb:A, 4hyb:B, 7jmm:A, 4jn4:A, 4jn4:B, 4jne:A, 4jne:B, 7jn8:A, 7jn9:A, 7jne:A, 4jwc:A, 4jwc:B, 4jwd:B, 4jwd:A, 4jwe:A, 4jwe:B, 4jwi:A, 4jwi:B, 7ko2:A, 7ko2:B, 7ko2:C, 7ko2:D, 7krt:A, 7krt:B, 7krt:C, 7krt:D, 7kru:B, 7kru:A, 7krv:B, 7krv:A, 7krw:C, 7krw:B, 7krw:D, 7kzi:A, 7kzi:B, 7kzu:A, 7n46:A, 7n6j:A, 7n6k:A, 7n6l:A, 7n6m:A, 5nro:A, 5oow:A, 5oow:B, 1q5l:A, 3qnj:A, 3qnj:B, 4r5g:B, 4r5i:A, 4r5j:A, 4r5j:C, 4r5j:B, 4r5j:D, 4r5k:A, 4r5k:B, 7rax:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218