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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MDVNPTLLFLKVPVQNAISTTFPYTGDPPYSHGTGTGYTMDTVNRTHKYSEKGKWTTNTETGAPQLNPIDGPLPEDNEPS
GYAQTDCVLEAMAFLEESHPGIFENSCLETMEIVQQTRVDKLTQGRQTYDWTLNRNQPAATALANTIEVFRSNGLTANES
GRLIDFLKDVMDSMDKEEMEITTHFQRKRRVRDNMTKKMVTQRTIGKKKQRLNKRSYLIRALTLNTMTKDAERGKLKRRA
IATPGMQIRGFVYFVEALARSICEKLEQSGLPVGGNEKKAKLANVVRKMMTNSQDTELSFTITGDNTKWNENQNPRMFLA
MITYITRNQPEWFRNVLSIAPIMFSNKMARLGKGYMFESKSMKLRTQVPAEMLANIDLKYFNKSTREKIEKIRPLLIDGT
ASLSPGMMMGMFNMLSTVLGVSILNLGQKKYTKTTYWWDGLQSSDDFALIVNAPNHEGIQAGVDRFYRTCKLVGINMSKK
KSYINRTGTFEFTSFFYRYGFVANFSMELPSFGVSGINESADMSVGVTVIKNNMINNDLGPATAQMALQLFIKDYRYTYR
CHRGDTQIQTRRAFELGKLWEQTRSKAGLLVSDGGPNLYNIRNLHIPEVCLKWELMDEDYQGRLCNPMNPFVSHKEIDSV
SMEYDAVATTHSWIPKRNRSILNTSQRGILEDEQMYQKCCNLFEKFFPSSSYRRPVGISSMVEAMVSRARIDARIDFESG
RIKKEEFAEIMKICSTIEELRRQK

The query sequence (length=744) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8h69:B 754 754 0.9731 0.9602 0.9602 0.0 7ni0:B, 8pnq:B, 8r3k:B, 8r3l:B, 6rr7:B
2 7nha:B 735 756 0.9449 0.9565 0.9299 0.0 8bek:B, 7nhx:B, 7nik:B, 7nil:B, 7nir:B, 7nis:B, 7nj3:B, 7nj4:B, 7nj5:B, 7nj7:B, 7nk1:B, 7nk2:B, 7nk4:B, 7nk6:B, 7nk8:B, 7nka:B, 7nkc:B, 7nki:B, 7nkr:B, 8pm0:B, 8pnp:B, 8poh:F, 7qtl:B, 6qx3:B, 6qx8:B, 6qx8:F, 6qxe:B, 6qxe:F, 7r0e:B, 8r60:B, 8r65:B, 7z4o:EEE, 7z4o:BBB, 7zpl:B, 7zpl:E
3 7nhc:B 717 743 0.9409 0.9763 0.9421 0.0 8rmr:B, 8rms:B
4 8rmq:B 694 743 0.9328 1.0000 0.9341 0.0 6tu5:BBB, 6tu5:EEE
5 6evj:B 752 756 0.7796 0.7713 0.7672 0.0 6evj:E, 6evk:B, 9f2r:B, 9f37:B, 6fhh:B, 6fhi:B, 5m3h:B, 6szu:B, 6szv:B, 6t0n:B, 6t0r:B, 6t0s:B, 6t0u:B, 6t0v:B, 6t2c:B, 6tw1:B, 4wsb:B
6 5epi:B 756 738 0.6048 0.5952 0.6098 0.0 8bdr:B, 8be0:B, 8bf5:B, 5epi:F, 5epi:J, 5epi:N, 5epi:R, 5epi:V, 6f5o:B, 5fmz:E, 5m3j:B, 5msg:B, 6qcs:B, 6qct:B, 6qcv:B, 6qcw:B, 6qcx:B, 7r1f:B, 8rn1:B, 8rn4:B, 8rn5:B, 8rn7:B, 8rn8:E, 8rn9:B, 8rnc:B, 6t0w:B, 4wrt:B, 4wsa:B, 7z42:E, 7z42:B, 7z43:BBB
7 5fmz:B 708 732 0.5927 0.6229 0.6025 0.0 8rn8:B
8 6qwl:K 539 654 0.4422 0.6104 0.5031 0.0
9 6xzd:BP1 712 739 0.3817 0.3989 0.3843 5.13e-171 6xzp:BP1, 6xzq:B, 6xzr:BP1, 6y0c:B
10 6kuj:B 705 754 0.3965 0.4184 0.3912 4.59e-169 6kuk:B, 6kup:B, 6kur:B, 6kut:B, 6kuu:B, 6kuv:B
11 8z8x:B 710 733 0.2755 0.2887 0.2797 8.92e-71 8z90:B
12 8z9h:B 676 724 0.2728 0.3003 0.2804 1.60e-66 8p0b:B, 8p0g:B, 8p0u:B, 8z85:B, 8z8j:B, 8z8n:B, 8z97:B, 8z9h:I, 8z9r:B, 8z9r:I
13 8z98:B 647 714 0.2621 0.3014 0.2731 1.71e-61 8z9q:B
14 8psn:B 515 291 0.0927 0.1340 0.2371 0.023 8pso:B, 8psq:B, 8pss:B, 8psu:B, 8psx:B, 8psz:B, 8pt2:B, 8pt6:B, 8pt7:B, 8pth:B, 8ptj:B, 8qz8:B
15 6l8h:A 466 117 0.0349 0.0558 0.2222 0.63 6l8h:B, 6l8h:C, 6l8h:D
16 7elb:A 1937 121 0.0349 0.0134 0.2149 0.69 7ckm:A, 7elb:C, 6kld:A, 6kle:A, 6klh:A, 6klh:C
17 6azy:A 810 91 0.0349 0.0321 0.2857 0.91 6d00:1, 6d00:2, 6d00:3, 6d00:4, 6d00:5, 6d00:6
18 7el9:A 1731 120 0.0349 0.0150 0.2167 0.96 7el9:D, 7elc:A
19 7eju:A 1648 120 0.0363 0.0164 0.2250 1.3
20 9c4g:2 67 66 0.0269 0.2985 0.3030 1.5 8crx:2, 8cvm:2
21 1mqq:A 675 48 0.0242 0.0267 0.3750 6.3 1k9e:A, 1k9f:A, 1l8n:A
22 4ews:A 472 29 0.0175 0.0275 0.4483 6.3 4f2a:A, 2obd:A
23 1iq3:A 110 31 0.0175 0.1182 0.4194 6.7
24 1ece:A 358 30 0.0148 0.0307 0.3667 9.8 1ece:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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