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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
LIPKADRKAIHEYLFREGVMVAAKDYESMHEIGVRNLYVIKALQSLQSRGYVKTQFSWQYYYYTLTPAGLDYLREWLHLP
AEIVPATHI

The query sequence (length=89) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7r81:L2 90 89 0.9101 0.9000 0.9101 1.18e-57 7olc:SK, 7old:SK, 8oo0:SK, 7z3n:SK, 7z3o:SK
2 8bn3:C0 96 91 0.6966 0.6458 0.6813 4.59e-41 7a1g:C, 7b7d:C, 8bqd:C, 8bqx:C, 8cah:C, 8cas:D, 8ccs:n, 8cdl:n, 8cdr:n, 8cf5:n, 8cku:n, 5dat:C0, 5dat:c0, 5dc3:C0, 5dc3:c0, 5dge:C0, 5dge:c0, 5dgf:C0, 5dgf:c0, 5dgv:C0, 5dgv:c0, 8eub:BK, 8evp:BK, 8evq:BK, 8evr:BK, 8evs:BK, 8evt:BK, 8ewb:BK, 8ewc:BK, 5fci:C0, 6gq1:AA, 6gqb:AA, 6gqv:AA, 6hhq:L, 6hhq:c0, 5i4l:C0, 5i4l:c0, 6i7o:C, 6i7o:Cb, 3j6x:10, 3j6y:10, 3j77:10, 3j78:10, 5juo:HB, 5jup:HB, 5jus:HB, 5jut:HB, 5juu:HB, 8k2d:SK, 8k82:SK, 5m1j:K2, 5mc6:C, 5mei:c0, 5mei:L, 7mpi:BK, 7mpj:BK, 7n8b:BK, 5ndg:C0, 5ndg:c0, 5ndv:C0, 5ndv:c0, 5ndw:C0, 5ndw:c0, 7nrc:SC, 7nrd:SC, 5obm:C0, 5obm:c0, 5on6:c0, 5on6:L, 7osa:eS10, 6q8y:C, 6rbe:K, 7rr5:SK, 6s47:BL, 6snt:K, 6sv4:C, 6sv4:Cb, 6sv4:Cc, 6t4q:SK, 6t7i:SK, 6t7t:SK, 6t83:Kb, 6t83:l, 5tbw:L, 5tbw:c0, 6tb3:C, 5tga:C0, 5tgm:C0, 5tgm:c0, 6tnu:C, 4u3m:C0, 4u3m:c0, 4u3n:C0, 4u3n:c0, 4u3u:C0, 4u3u:c0, 4u4n:C0, 4u4n:c0, 4u4o:C0, 4u4o:c0, 4u4q:C0, 4u4q:c0, 4u4r:C0, 4u4r:c0, 4u4u:C0, 4u4u:c0, 4u4y:C0, 4u4y:c0, 4u4z:C0, 4u4z:c0, 4u50:C0, 4u50:c0, 4u51:C0, 4u51:c0, 4u52:C0, 4u52:c0, 4u53:C0, 4u53:c0, 4u55:C0, 4u55:c0, 4u56:C0, 4u56:c0, 4u6f:C0, 4u6f:c0, 4uer:7, 4v88:AK, 4v88:CK, 4v8y:AK, 4v8z:AK, 4v92:BK, 6wdr:K, 6woo:KK, 6xiq:AA, 6xir:AA, 6z6j:SK, 6z6k:SK, 6zce:L, 7zpq:AK, 7zrs:AK, 6zu9:D, 7zuw:AK, 7zux:DK, 6zvi:s, 7zw0:sC
3 6fyx:K 96 91 0.6517 0.6042 0.6374 1.55e-37 6fyy:K, 6gsm:K, 6gsn:K, 8i7j:K, 5it7:K, 5it9:K, 3j80:K, 3j81:K, 3jam:K, 3jap:K, 8rw1:K, 8s8d:K, 8s8e:K, 8s8f:K, 8s8g:K, 8s8h:K, 8s8i:K, 8s8j:K, 6uz7:K
4 8c3a:M 98 91 0.6517 0.5918 0.6374 1.63e-37 8c3a:CX, 8cgn:n, 8cq7:M, 8cq7:CX, 8cqw:M, 8cqw:CX, 8cre:M, 8cre:CX, 8oeq:M, 8oeq:CX, 7pzy:L, 7q08:L, 7q0f:L, 7q0p:L, 7q0r:L, 8q5i:L
5 5fci:c0 96 82 0.6292 0.5833 0.6829 1.22e-36 5fcj:C0, 5fcj:c0, 5lyb:C0, 5lyb:c0, 5tga:c0
6 9bkd:a 99 92 0.5843 0.5253 0.5652 9.11e-32 7a01:E3, 7a09:u, 5a2q:K, 5aj0:BK, 9bdl:AS10, 9bdn:AS10, 9bdp:AS10, 8bhf:L3, 9bln:a, 8btk:Aj, 7cpu:SK, 7cpv:SK, 4d5l:K, 4d61:K, 6d90:LL, 6d9j:LL, 9f1b:Aj, 9f1c:Aj, 9f1d:Aj, 6fec:t, 5flx:K, 6g51:K, 6g53:K, 6g5h:K, 6g5i:K, 8g5y:SK, 8g5z:SK, 8g60:SK, 8g61:SK, 8g6j:SK, 8glp:SK, 6gz3:BK, 6gz4:BK, 6gz5:BK, 6hcf:L1, 6hcj:L2, 6hcm:L1, 6hcq:L2, 8ifd:2u, 8ife:2u, 6ip5:2u, 6ip6:2u, 6ip8:2u, 3j7p:SK, 3j7r:SK, 3jag:KK, 3jah:KK, 3jai:KK, 3jaj:SK, 3jan:SK, 8jdj:7, 8jdk:7, 8jdl:7, 8jdm:7, 7jqb:L, 7jqc:L, 5k0y:t, 8k2c:SK, 7k5i:K, 4kzx:K, 4kzy:K, 4kzz:K, 5lks:SK, 7ls1:v2, 7ls2:v2, 5lzs:KK, 5lzt:KK, 5lzu:KK, 5lzv:KK, 5lzw:KK, 5lzx:KK, 5lzy:KK, 5lzz:KK, 7mdz:KK, 6mtb:KK, 6mtc:KK, 6mtd:KK, 6mte:KK, 7nwg:L2, 7nwh:KK, 7nwi:KK, 7o7y:Aj, 7o7z:Aj, 7o80:Aj, 7o81:Aj, 5oa3:K, 6ole:SK, 6olf:SK, 6olg:BK, 6oli:SK, 6olz:BK, 6om0:SK, 6om7:SK, 7oya:K2, 7oyb:K2, 7oyc:K2, 7oyd:KK, 8oz0:i, 8p03:M, 8p09:M, 8p2k:Aj, 6p4g:L, 6p4h:L, 6p5i:L, 6p5j:L, 6p5k:L, 6p5n:L, 8pj1:a, 8pj2:a, 8pj3:a, 8pj4:a, 8pj5:a, 8pj6:a, 8ppk:K, 8ppl:AK, 8q7z:Aj, 8q87:Aj, 7qgg:SK, 8qoi:SK, 7qp6:a, 7qp7:a, 7qvp:SK, 7qvp:RK, 6qzp:SK, 7r4x:K, 6r5q:SS, 6r6g:SS, 6r6p:SS, 6r7q:SS, 8scb:KK, 6sgc:L1, 7syg:L, 7syh:L, 7syi:L, 7syj:L, 7syk:L, 7syl:L, 7sym:L, 7syn:L, 7syo:L, 7syp:L, 7syq:L, 7syr:L, 7sys:L, 7syt:L, 7syu:L, 7syv:L, 7syw:L, 7syx:L, 5t2c:Av, 8t4s:K, 7toq:AS10, 7tor:AS10, 7tql:M, 7ucj:KK, 7uck:KK, 4ug0:SK, 4ujc:CK, 4ujd:CK, 4uje:BK, 4v6x:AK, 5vyc:K1, 5vyc:K2, 5vyc:K3, 5vyc:K4, 5vyc:K5, 5vyc:K6, 6w2s:L, 6w2t:L, 6xa1:SK, 7xnx:SK, 7xny:SK, 8xsx:SK, 8xsy:SK, 8xsz:SK, 8xxl:SK, 8xxm:SK, 8xxn:SK, 6y0g:SK, 8y0w:SK, 8y0x:SK, 6y2l:SK, 6y57:SK, 6yal:M, 6yam:M, 6yan:M, 6ybs:a, 8yoo:SK, 8yop:SK, 6z6l:SK, 6z6m:SK, 6z6n:SK, 7zjw:SV, 7zjx:SV, 6zlw:M, 6zm7:SK, 6zme:SK, 6zmi:SK, 6zmo:SK, 6zmt:M, 6zmw:a, 6zn5:M, 6zoj:K, 6zol:K, 6zon:u, 6zp4:u, 6zuo:K, 6zv6:K, 6zvh:K, 6zvj:u, 6zvk:E3, 6zxd:K, 6zxe:K, 6zxf:K, 6zxg:K, 6zxh:K
7 4v6w:AK 95 90 0.5618 0.5263 0.5556 2.53e-29
8 6xu6:AK 90 89 0.5506 0.5444 0.5506 4.57e-29 6xu7:AK, 6xu8:AK
9 9bh5:AK 93 90 0.5955 0.5699 0.5889 1.05e-28 9cai:AK
10 4v7e:BK 96 89 0.5506 0.5104 0.5506 2.35e-28 8ip8:da, 8ip9:da, 8ipa:da, 8ipb:da, 8jiw:BK, 8r57:K
11 6zj3:SN 92 88 0.4944 0.4783 0.5000 3.11e-28
12 5xxu:K 94 89 0.5056 0.4787 0.5056 8.08e-28
13 7qiy:F 92 89 0.5056 0.4891 0.5056 8.84e-26 8auv:l, 8b2l:l1, 7qiz:PA
14 4v8m:AD 103 94 0.3708 0.3204 0.3511 2.74e-18 8ova:AD, 8ove:AD
15 3j7a:O 79 76 0.3708 0.4177 0.4342 3.49e-18 3jbn:O, 3jbo:O, 3jbp:O, 6okk:O, 8tpu:SO
16 7qca:SK0 91 89 0.4045 0.3956 0.4045 3.73e-16 8p5d:SK0, 8p60:SK0, 8p60:RK0
17 7ase:N 93 92 0.3483 0.3333 0.3370 1.69e-15 5opt:n
18 8a98:SN 101 94 0.3371 0.2970 0.3191 1.83e-15 8a3w:SN, 6az1:N, 8ovj:SN, 8rxh:SN, 8rxx:SN, 5t2a:AD
19 4v5o:A7 104 88 0.3596 0.3077 0.3636 3.78e-14 4bts:A7, 4bts:B7, 4bts:C7, 4bts:D7, 4v5o:B7
20 5xyi:K 90 87 0.3258 0.3222 0.3333 3.47e-12
21 7pwf:K 83 80 0.3596 0.3855 0.4000 3.86e-10
22 8bsj:SL 109 98 0.3708 0.3028 0.3367 7.85e-10 8br8:SL, 8brm:SL, 8bsi:SL, 8btd:SL, 8btr:SL, 8fvy:K, 8g4s:K
23 8ceh:n 33 62 0.2921 0.7879 0.4194 1.84e-07 8cg8:n, 8civ:n, 8cmj:n, 7osm:eS10
24 6zu5:SK0 74 74 0.2472 0.2973 0.2973 6.25e-07
25 6rm3:SK0 85 83 0.2135 0.2235 0.2289 1.31e-04
26 7qep:C0 81 47 0.1798 0.1975 0.3404 0.004
27 7ou2:B 650 17 0.1011 0.0138 0.5294 2.9
28 1ng9:A 794 17 0.1011 0.0113 0.5294 3.0 7ai5:B, 7ai5:A, 7ai6:A, 7ai6:B, 7ai7:A, 7ai7:B, 7aib:B, 7aib:A, 7aic:A, 7aic:B, 5akb:A, 5akb:B, 5akc:A, 5akc:B, 5akc:E, 5akc:F, 5akc:I, 5akc:J, 5akd:A, 5akd:B, 5akd:E, 5akd:F, 5akd:I, 5akd:J, 1e3m:A, 1e3m:B, 6i5f:A, 6i5f:B, 3k0s:A, 3k0s:B, 1ng9:B, 1oh5:A, 1oh5:B, 1oh6:A, 1oh6:B, 1oh7:A, 1oh7:B, 1oh8:A, 1oh8:B, 1w7a:A, 1w7a:B, 1wb9:A, 1wb9:B, 1wbb:A, 1wbb:B, 1wbd:A, 1wbd:B, 2wtu:A, 2wtu:B, 3zlj:A, 3zlj:B
29 7ou2:A 721 17 0.1011 0.0125 0.5294 3.1 5akb:E, 7oto:B, 7oto:A, 7ou0:B, 7ou0:A, 7ou4:A, 7ou4:B
30 6kqs:A 620 54 0.1798 0.0258 0.2963 3.2 6kqt:A
31 8dgf:A 1541 47 0.1461 0.0084 0.2766 4.8 8dgf:B, 8dgf:C, 8dgf:D
32 4q5h:A 169 38 0.1573 0.0828 0.3684 5.2
33 2d73:A 717 78 0.2360 0.0293 0.2692 6.0 2d73:B, 2jka:A, 2jka:B, 2jke:A, 2jke:B, 2jkp:A, 2jkp:B, 3wfa:A, 3wfa:B, 2zq0:A, 2zq0:B
34 7sfz:A 100 26 0.1124 0.1000 0.3846 6.1 7sfz:B, 7sfz:C, 7sfz:D, 7sfz:E, 7sfz:F, 7sfz:G
35 3l4g:C 508 48 0.1685 0.0295 0.3125 9.0 3l4g:A, 3l4g:E, 3l4g:G, 3l4g:I, 3l4g:K, 3l4g:M, 3l4g:O
36 1uz4:A 410 52 0.1910 0.0415 0.3269 9.5 7odj:AAA

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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