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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
LIKKKNKDIRIIPLGGVGEIAKNMYIVEVDDEMFMLDAGLMFPEDEMLGVDIVIPDIQYVIENKERLKGIFLTHGHEHAI
GAVSYVLEQIDAPVYGSKLTIALVKEAMKARNIKKKVRYYTVNHDSIMRFKNVNVSFFNTTHSIPDSLGVCIHTSYGSIV
YTGEFKFDQSLHGHYAPDLKRMAEIGDEGVFALISDSTEAEKPGYNTPENIIEHHMYDAFAKVKGRLIVSCYASNFVRIQ
QVLNIASQLNRKVSFLGRSLESSFNIARKMGYFDIPKDLLIPINEVENYPKNEVIIIATGMQGEPVEALSQMARKKHKIM
NIEEGDSIFLAITASANMEVIIADTLNELVRAGAHIIPNNKKIHASSHGCMEELKMMLNIMKPEYFVPVQGEFKMQIAHA
KLAAETGVAPEKIFLVEKGDVISYNGKDMILNEKVQSGNILID

The query sequence (length=443) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6k6w:C 444 443 1.0000 0.9977 1.0000 0.0 6k6w:A, 6k6w:B, 6k6w:D
2 3zq4:A 550 440 0.4266 0.3436 0.4295 1.28e-134 3zq4:C, 3zq4:D, 3zq4:E
3 6k6s:A 443 439 0.3634 0.3634 0.3667 3.57e-112 6k6s:B
4 5a0t:A 454 440 0.3770 0.3678 0.3795 2.09e-103 5a0t:B, 5a0v:A, 5a0v:B
5 7wnu:B 554 437 0.3454 0.2762 0.3501 1.21e-93 7wnt:A, 7wnu:A
6 3t3o:A 553 426 0.3612 0.2893 0.3756 2.05e-93 3bk1:A, 3bk2:A, 3t3n:A
7 4xww:A 545 440 0.3318 0.2697 0.3341 2.04e-89 4xwt:A, 4xwt:B, 4xww:B
8 5hab:B 463 453 0.2867 0.2743 0.2804 1.24e-49 5haa:A, 5haa:B, 5hab:A, 6llb:A, 6llb:B, 5ws2:A, 5ws2:B
9 3af5:A 638 188 0.1016 0.0705 0.2394 1.58e-05 3af6:A
10 8rbx:k 552 102 0.0609 0.0489 0.2647 7.22e-05 7pks:k, 8rbz:k
11 7ycx:K 590 102 0.0609 0.0458 0.2647 8.52e-05 7cun:K, 8r22:C, 8r23:C, 8r2d:C, 8rc4:k, 8uib:K
12 9bct:M 648 277 0.1332 0.0910 0.2130 1.89e-04 9bct:J, 9bcu:J, 9bcu:M
13 7sn8:K 588 185 0.0880 0.0663 0.2108 5.64e-04 8uic:K
14 6jka:C 228 147 0.0767 0.1491 0.2313 6.55e-04 4c1f:A, 4c1f:B, 4c1g:A, 4c1g:B, 1dd6:A, 1dd6:B, 1ddk:A, 2doo:A, 2doo:B, 7dtm:A, 7dtm:B, 7dtm:C, 7dtm:D, 7dtn:A, 7dtn:B, 7dtn:C, 7dtn:D, 5ev6:A, 5ev6:B, 5ev6:C, 5ev6:D, 5ev8:A, 5ev8:C, 5ev8:B, 5ev8:D, 5ewa:A, 5ewa:B, 5ewa:C, 5ewa:D, 4f6h:A, 4f6z:A, 5hh4:A, 5hh4:B, 5hh4:C, 5hh4:D, 8hyb:A, 8hyb:B, 8hyb:C, 8hyb:D, 8jao:A, 8jao:B, 6jed:A, 1jje:A, 1jje:B, 1jjt:A, 1jjt:B, 6jka:A, 6jka:B, 6jka:D, 6lbl:A, 4uam:A, 4uam:B, 4uam:C, 4uam:D, 1vgn:A, 1vgn:B, 1wuo:A, 1wuo:B, 1wuo:C, 1wuo:D, 1wup:A, 1wup:B, 1wup:C, 1wup:D, 3wxc:A, 3wxc:B, 7wzu:A, 7wzu:B, 7wzu:C, 7wzu:D, 7xhw:A, 7xhw:B, 7xhw:C, 7xhw:D, 7xhx:A, 7xhx:B, 7xhx:C, 7xhx:D, 8y0s:A, 8y0s:B, 8y0s:C, 8y0s:D, 5y5b:A, 7yh9:A, 7yh9:B, 7yh9:C, 7yh9:F, 7yh9:D, 7yh9:E, 7yha:A, 7yha:B, 7yha:C, 7yha:D, 8z5l:A, 8z5l:B, 8z5l:C, 8z5l:D, 6zyr:A, 6zyr:B, 6zyr:C, 6zyr:D, 6zys:A, 6zys:B, 6zys:C, 6zys:D
15 6r79:A 220 109 0.0609 0.1227 0.2477 0.001 6r73:A, 6r73:B, 6r78:A, 6r78:B, 6r79:D, 6r79:B, 6r79:C, 6rzr:A, 6rzr:B, 6rzs:A, 6rzs:B, 6s0h:A, 6s0h:B, 4ubq:A, 6yi4:AAA, 6yi4:BBB, 6yi4:CCC
16 2xr1:B 611 190 0.0745 0.0540 0.1737 0.003 2xr1:A
17 6l3s:A 218 107 0.0564 0.1147 0.2336 0.004 6l3s:B
18 2zwr:B 207 184 0.0948 0.2029 0.2283 0.004 2zwr:A, 2zzi:A, 2zzi:B
19 7l0b:A 202 93 0.0587 0.1287 0.2796 0.004 7l0b:B, 7l0b:C, 7l0b:D
20 5b3r:B 219 96 0.0542 0.1096 0.2500 0.022 5b3r:A
21 2ycb:B 635 191 0.0903 0.0630 0.2094 0.031 2ycb:A
22 6v4x:I 510 82 0.0497 0.0431 0.2683 0.046
23 7a1f:L 335 107 0.0564 0.0746 0.2336 0.089 7a1f:A, 5aho:A
24 3a4y:A 431 171 0.0722 0.0742 0.1871 0.32 3a4y:B, 3a4y:C, 3a4y:D, 2dkf:A, 2dkf:B, 2dkf:C, 2dkf:D, 3idz:A, 3idz:B, 3idz:C, 3idz:D, 3ie0:A, 3ie0:B, 3ie0:C, 3ie0:D, 3ie1:A, 3ie1:B, 3ie1:C, 3ie1:D, 3ie2:A, 3ie2:B, 3ie2:C, 3ie2:D, 3iek:A, 3iek:B, 3iek:C, 3iek:D, 3iel:A, 3iel:B, 3iel:C, 3iel:D, 3iem:A, 3iem:B, 3iem:D, 3iem:C
25 5mmd:E 221 168 0.0993 0.1991 0.2619 0.49 5mmd:F
26 7ev5:A 209 177 0.0993 0.2105 0.2486 0.59
27 4wd6:A 219 166 0.0903 0.1826 0.2410 0.66 4wd6:B, 4zej:A, 4zej:B
28 1c3o:B 379 62 0.0497 0.0580 0.3548 0.84 1c3o:D, 1c3o:F, 1c3o:H, 1ce8:B, 1ce8:D, 1ce8:F
29 4zo2:B 294 65 0.0384 0.0578 0.2615 1.2 4zo2:A, 4zo3:A, 4zo3:B
30 8z99:H 582 502 0.2460 0.1873 0.2171 1.7 8yhd:I, 8yhd:L, 8yhe:I, 8yhe:L, 8z4j:H, 8z4j:I, 8z4j:L, 8z4l:H, 8z4l:I, 8z4l:L, 8z99:I, 8z99:L, 8z9c:H, 8z9c:I, 8z9c:L, 8z9e:I, 8z9e:L
31 3s4a:A 822 88 0.0609 0.0328 0.3068 1.8 3s4a:B, 3s4b:A, 3s4b:B, 3s4d:A
32 3e7f:B 263 35 0.0293 0.0494 0.3714 2.3 3e7f:A, 3eb9:A, 3eb9:B, 2j0e:A, 2j0e:B
33 6v4x:H 499 186 0.0903 0.0802 0.2151 4.5 6m8q:A, 6m8q:B
34 2i7v:A 433 187 0.0813 0.0831 0.1925 5.0 8t1q:A, 8t1r:A
35 8z9e:H 553 317 0.1535 0.1230 0.2145 5.5
36 5tc1:M 330 36 0.0361 0.0485 0.4444 6.0
37 5mrc:d 206 49 0.0384 0.0825 0.3469 7.3 3j6b:d, 5mre:d, 5mrf:d
38 6i1d:A 458 86 0.0429 0.0415 0.2209 8.4
39 3jxe:B 363 70 0.0406 0.0496 0.2571 9.3 3jxe:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218