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TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
LDQWRSRQKIGMGKGARCCVICSNQKALIRKYELNVCRQCFRENAEHIGFTKLR

The query sequence (length=54) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8rxh:SS 56 54 1.0000 0.9643 1.0000 3.01e-35 8a3w:SS, 8a98:SS, 6az1:S, 8ove:A8, 8ovj:SS, 8rxx:SS, 5t2a:8
2 7ase:Q 57 54 0.8704 0.8246 0.8704 5.59e-30 5opt:q, 8ova:A8, 4v8m:A8
3 7r81:e2 55 51 0.5556 0.5455 0.5882 9.74e-16 7olc:Sd, 7old:Sd, 8oo0:Sd, 7z3n:Sd, 7z3o:Sd
4 4v6w:Ad 52 42 0.5185 0.5385 0.6667 7.90e-15 6xu6:Ad, 6xu7:Ad, 6xu8:Ad
5 7a1g:M 53 43 0.5000 0.5094 0.6279 3.48e-14 7b7d:M, 8bn3:D9, 8bqd:M, 8bqx:M, 8cah:M, 8cas:N, 8cbj:d, 8ccs:5, 8cdl:5, 8cdr:5, 8ceh:5, 8cf5:5, 8cg8:5, 8cgn:5, 8civ:5, 8cku:5, 8cmj:5, 5dat:D9, 5dat:d9, 5dc3:D9, 5dc3:d9, 5dge:D9, 5dge:d9, 5dgf:D9, 5dgf:d9, 5dgv:D9, 5dgv:d9, 8eub:Bd, 8evp:Bd, 8evq:Bd, 8evr:Bd, 8evs:Bd, 8evt:Bd, 8ewb:Bd, 8ewc:Bd, 6fai:d, 5fci:D9, 5fci:d9, 5fcj:D9, 5fcj:d9, 6gq1:AT, 6gqb:AT, 6gqv:AT, 6hhq:e, 6hhq:d9, 5i4l:D9, 5i4l:d9, 6i7o:M, 6i7o:Mb, 3j6x:29, 3j6y:29, 3j77:29, 3j78:29, 5juo:AC, 5jup:AC, 5jus:AC, 5jut:AC, 5juu:AC, 8k2d:Sd, 8k82:Sd, 5lyb:D9, 5lyb:d9, 5m1j:d2, 5mc6:M, 5mei:d9, 5mei:e, 7mpi:Bd, 7mpj:Bd, 7n8b:Bd, 5ndg:D9, 5ndg:d9, 5ndv:D9, 5ndv:d9, 5ndw:D9, 5ndw:d9, 7nrc:SM, 7nrd:SM, 5obm:D9, 5obm:d9, 5on6:d9, 5on6:e, 7osa:uS14, 7osm:uS14, 6q8y:M, 6rbd:d, 6rbe:d, 7rr5:Sd, 6s47:Be, 6snt:d, 6sv4:M, 6sv4:Mb, 6sv4:Mc, 6t4q:Sd, 6t7i:Sd, 6t7t:Sd, 6t83:db, 6t83:4, 5tbw:e, 5tbw:d9, 6tb3:M, 5tga:D9, 5tga:d9, 5tgm:D9, 5tgm:d9, 6tnu:M, 4u3m:D9, 4u3m:d9, 4u3n:D9, 4u3n:d9, 4u3u:D9, 4u3u:d9, 4u4n:D9, 4u4n:d9, 4u4o:D9, 4u4o:d9, 4u4q:D9, 4u4q:d9, 4u4r:D9, 4u4r:d9, 4u4u:D9, 4u4u:d9, 4u4y:D9, 4u4y:d9, 4u4z:D9, 4u4z:d9, 4u50:D9, 4u50:d9, 4u51:D9, 4u51:d9, 4u52:D9, 4u52:d9, 4u53:D9, 4u53:d9, 4u55:D9, 4u55:d9, 4u56:D9, 4u56:d9, 4u6f:D9, 4u6f:d9, 4uer:N, 4v6i:AN, 4v7h:AN, 4v7r:AS, 4v7r:CS, 4v88:Ad, 4v88:Cd, 4v8y:A3, 4v8z:A3, 4v92:Bd, 6wdr:d, 6woo:dd, 6xiq:AT, 6xir:AT, 8y0u:Sd, 6z6j:Sd, 6z6k:Sd, 6zce:e, 7zpq:Ad, 7zrs:Ad, 6zu9:N, 7zuw:Ad, 7zux:Dd, 6zvi:O, 7zw0:sM
6 3j7a:T 48 43 0.4815 0.5417 0.6047 4.19e-14 3jbn:T, 3jbo:T, 3jbp:T, 6okk:T, 8tpu:ST
7 5a2q:d 55 42 0.4815 0.4727 0.6190 6.89e-14 7a01:H3, 7a09:l, 5aj0:Bd, 9bdl:AS29, 9bdn:AS29, 9bdp:AS29, 8bhf:e3, 9bkd:i, 9bln:i, 8btk:AG, 7cpu:Sd, 7cpv:Sd, 4d5l:d, 4d61:d, 6d90:ee, 6d9j:ee, 9f1b:AG, 9f1c:AG, 9f1d:AG, 6fec:J, 5flx:d, 6g51:d, 6g53:d, 6g5h:d, 6g5i:d, 8g5y:Sd, 8g5z:Sd, 8g60:Sd, 8g61:Sd, 8g6j:Sd, 8glp:Sd, 6gz3:Bd, 6gz4:Bd, 6gz5:Bd, 6hcf:e1, 6hcj:e2, 6hcm:e1, 6hcq:e2, 8ifd:3E, 8ife:3E, 6ip5:3E, 6ip6:3E, 6ip8:3E, 3j7p:Sd, 3j7r:Sd, 3jag:dd, 3jah:dd, 3jai:dd, 3jaj:Sd, 3jan:Sd, 8jdj:AP, 8jdk:AP, 8jdl:AP, 8jdm:AP, 5k0y:J, 8k2c:Sd, 7k5i:d, 4kzx:d, 4kzy:d, 4kzz:d, 5lks:Sd, 7ls1:H3, 7ls2:H3, 5lzs:dd, 5lzt:dd, 5lzu:dd, 5lzv:dd, 5lzw:dd, 5lzx:dd, 5lzy:dd, 5lzz:dd, 7mdz:dd, 6mtb:dd, 6mtc:dd, 6mtd:dd, 6mte:dd, 7nwg:e2, 7nwh:dd, 7nwi:dd, 7o7y:AG, 7o7z:AG, 7o80:AG, 7o81:AG, 5oa3:d, 6ole:Sd, 6olf:Sd, 6olg:Bd, 6oli:Sd, 6olz:Bd, 6om0:Sd, 6om7:Sd, 7oya:d2, 7oyb:d2, 7oyc:d2, 7oyd:Dd, 8oz0:o, 8p03:e, 8p09:e, 8p2k:AG, 6p4g:e, 6p4h:e, 6p5i:e, 6p5j:e, 6p5k:e, 6p5n:e, 8pj1:i, 8pj2:i, 8pj3:i, 8pj4:i, 8pj5:i, 8pj6:i, 8ppk:d, 8ppl:Ad, 8q7z:AG, 8q87:AG, 7qgg:Sd, 8qoi:Sd, 7qp6:i, 7qp7:i, 7qvp:Sd, 7qvp:Rd, 6qzp:Sd, 7r4x:d, 6r5q:9, 6r6g:9, 6r6p:w, 6r7q:9, 8scb:dd, 6sgc:e1, 7syg:e, 7syh:e, 7syi:e, 7syj:e, 7syk:e, 7syl:e, 7sym:e, 7syn:e, 7syo:e, 7syp:e, 7syq:e, 7syr:e, 7sys:e, 7syt:e, 7syu:e, 7syv:e, 7syw:e, 7syx:e, 5t2c:AG, 8t4s:d, 7toq:AS29, 7tor:AS29, 7tql:f, 7ucj:Dd, 7uck:Dd, 4ug0:Sd, 4ujc:Cd, 4ujd:Cd, 4uje:Bd, 4v5z:An, 4v6x:Ad, 5vyc:d1, 5vyc:d2, 5vyc:d3, 5vyc:d4, 5vyc:d5, 5vyc:d6, 6w2s:e, 6w2t:e, 6xa1:Sd, 7xnx:Sd, 7xny:Sd, 8xsx:Sd, 8xsy:Sd, 8xsz:Sd, 8xxl:Sd, 8xxm:Sd, 8xxn:Sd, 6y0g:Sd, 8y0w:Sd, 8y0x:Sd, 6y2l:Sd, 6y57:Sd, 6yal:e, 6yam:e, 6yan:e, 6ybs:i, 8yoo:Sd, 8yop:Sd, 6z6l:Sd, 6z6m:Sd, 6z6n:Sd, 7zjw:SH, 7zjx:SH, 6zlw:f, 6zm7:Sd, 6zme:Sd, 6zmi:Sd, 6zmo:Sd, 6zmt:f, 6zmw:i, 6zn5:f, 6zoj:d, 6zol:d, 6zon:l, 6zp4:l, 6zuo:d, 6zv6:d, 6zvh:d, 6zvj:l, 6zvk:H3, 6zxd:d, 6zxe:d, 6zxf:d, 6zxg:d, 6zxh:d
8 8auv:V 55 51 0.5000 0.4909 0.5294 8.78e-13 8b2l:V1, 7qiy:N, 7qiz:XA
9 8c3a:f 55 43 0.4815 0.4727 0.6047 1.72e-12 8c3a:DQ, 8cq7:f, 8cq7:DQ, 8cqw:f, 8cqw:DQ, 8cre:f, 8cre:DQ, 8oeq:f, 8oeq:DQ, 7pzy:e, 7q08:e, 7q0f:e, 7q0p:e, 7q0r:e, 8q5i:e
10 8r57:d 55 51 0.5000 0.4909 0.5294 3.24e-12 8ip8:wa, 8ip9:wa, 8ipa:wa, 8ipb:wa, 8jiw:Bd, 4v3p:SN, 4v7e:Bd
11 9bh5:Ad 55 42 0.4259 0.4182 0.5476 7.22e-12 9cai:Ad
12 4bts:AN 54 51 0.4444 0.4444 0.4706 1.54e-11 4bts:BN, 4bts:CN, 4bts:DN, 4v5o:AN, 4v5o:BN
13 5xxu:d 51 43 0.4259 0.4510 0.5349 1.94e-11
14 6fyx:d 55 43 0.4444 0.4364 0.5581 6.84e-11 6fyy:d, 6gsm:d, 6gsn:d, 8i7j:d, 5it7:d, 5it9:d, 3j80:d, 3j81:d, 3jam:d, 3jap:d, 8rw1:d, 8s8d:d, 8s8e:d, 8s8f:d, 8s8g:d, 8s8h:d, 8s8i:d, 8s8j:d, 6uz7:d
15 5xyi:d 52 40 0.3889 0.4038 0.5250 1.28e-09
16 6zu5:SDD 59 42 0.3704 0.3390 0.4762 4.00e-09
17 8hkx:S14P 52 43 0.3889 0.4038 0.4884 1.25e-08 8hky:S14P, 8hkz:S14P, 8hl1:S14P, 8hl2:S14P, 8hl3:S14P, 8hl4:S14P, 8hl5:S14P, 8wkp:S14P, 8wq2:S14P, 8wq4:S14P
18 8fvy:d 85 38 0.3889 0.2471 0.5526 3.53e-08 8br8:Sh, 8brm:Sh, 8bsi:Sh, 8bsj:Sh, 8btd:Sh, 8btr:Sh, 8g4s:d, 7pwf:d, 7pwo:d1
19 6tmf:Q 56 50 0.4074 0.3929 0.4400 4.71e-08
20 6rm3:SDD 67 44 0.3333 0.2687 0.4091 1.69e-07
21 5jb3:P 56 50 0.3889 0.3750 0.4200 3.42e-07 5jbh:P, 6skf:Ar, 6skg:Ar, 6sw9:P, 6swc:P, 6swe:P, 6th6:Ar, 4v4n:BP, 4v6u:AP, 7zag:P, 7zah:P, 7zai:P, 7zhg:P
22 7qep:D9 65 40 0.3889 0.3231 0.5250 4.15e-07
23 8p5d:SDD 65 50 0.3704 0.3077 0.4000 9.41e-07 8p60:SDD, 8p60:RDD, 7qca:SDD
24 6zj3:SS 52 51 0.4444 0.4615 0.4706 4.12e-04
25 2ogj:A 379 52 0.3148 0.0449 0.3269 0.33 2ogj:B, 2ogj:C, 2ogj:D, 2ogj:E, 2ogj:F
26 4bbj:A 664 26 0.2037 0.0166 0.4231 2.0 4bev:A, 4byg:A, 3rfu:A, 3rfu:B, 3rfu:C, 3rfu:D
27 7s3u:A 145 38 0.2407 0.0897 0.3421 2.3 7s3w:A, 7s41:A, 7s42:A, 7s43:A, 7s44:A, 7s45:A
28 7bkb:E 411 42 0.2778 0.0365 0.3571 2.5 7bkb:e, 7bkc:E, 7bkc:e, 7bkd:E, 7bke:E
29 6tda:L 596 36 0.2222 0.0201 0.3333 2.5
30 3cux:A 501 22 0.1852 0.0200 0.4545 2.8
31 5w8q:A 379 35 0.2037 0.0290 0.3143 3.8 5w8q:B, 5wc4:A, 5wc4:B
32 6k15:H 393 36 0.2222 0.0305 0.3333 4.1 6kw4:H, 6kw5:H, 6v8o:I, 6v92:I
33 6wcw:A 247 22 0.1667 0.0364 0.4091 5.9

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218