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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
LAQRLEGLRGYLDIPQKETRLKELERRLEDPSLWNDPEAARKVSQEAARLRRTVDTFRSLESDLQGLLELMEELPAEERE
ALKPELEEAAKKLDELYHQTLLNFPHAEKNAILTIQPGAGGTEACDWAEMLLRMYTRFAERQGFQVEVVDLTPGPEAGID
YAQILVKGENAYGLLSPEAGVHRLVRPSPFDASGRRHTSFAGVEVIPEVDEEVEVVLKPEELRIDVMRASGPGGQGVNTT
DSAVRVVHLPTGITVTCQTTRSQIKNKELALKILKARLYELERKKREEELKALRGEVRPIEWGSQIRSYVLDKNYVKDHR
TGLMRHDPENVLDGDLMDLIWAGLEWKAGRR

The query sequence (length=351) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4v4s:AY 365 351 1.0000 0.9616 1.0000 0.0 6c5l:AY, 6c5l:CY, 4v5e:AY, 4v5e:CY, 4v5j:AY, 4v5j:CY, 4v67:AX, 4v67:CX, 4v9n:AY, 4v9n:CY
2 5mdy:7 324 342 0.8860 0.9599 0.9094 0.0
3 6szs:z 362 352 0.4957 0.4807 0.4943 2.98e-117
4 6c4i:v 362 354 0.4843 0.4696 0.4802 2.50e-106 6c4h:v, 5czp:XY, 5czp:QY, 5dfe:QY, 5dfe:XY, 5h5u:4, 5mdv:7, 5mdw:7, 5mgp:z, 1ml5:Z, 7o1c:B9, 6og7:8, 6ogf:8, 6ogg:8, 7oj0:8, 6ost:7, 6ot3:A, 6ouo:A, 8p16:6, 8p17:6, 8p18:6, 8qk7:6, 5u4i:v, 5u9f:Z, 5u9g:Z
5 4v63:AX 354 322 0.3932 0.3898 0.4286 1.27e-71 4v4r:AY, 4v63:CX, 4v7p:AV, 4v7p:DV
6 7m5d:A 360 331 0.3533 0.3444 0.3746 9.55e-53 8akn:W, 6b4v:JA, 6b4v:NC, 6boh:JA, 6boh:OC, 6bok:GD, 6bok:HD, 6dnc:MA, 8fzd:w, 8fze:w, 8fzg:w, 8fzh:w, 6gwt:v, 6gxm:v, 6gxn:v, 6gxo:v, 5j30:QY, 5j30:XY, 5j3c:QY, 5j3c:XY, 5j4d:JA, 5j4d:OC, 5o2r:v, 6orl:A, 6osk:A, 6osq:A
7 7nqh:BL 250 231 0.2707 0.3800 0.4113 1.69e-51
8 8oin:Aa 381 334 0.3276 0.3018 0.3443 5.17e-46 8oip:Aa, 8oiq:Aa, 8oir:Aa, 8ois:Aa, 8oit:Aa
9 5u4j:v 132 102 0.1624 0.4318 0.5588 1.66e-33
10 5u4j:v 132 46 0.0484 0.1288 0.3696 0.006
11 7sa4:8 203 184 0.1709 0.2956 0.3261 8.89e-20
12 7a5h:C 114 62 0.0741 0.2281 0.4194 3.61e-09
13 6yss:y 139 123 0.1083 0.2734 0.3089 0.014 7jss:8, 7jsw:8, 7jsz:8, 7jt1:8, 7jt2:8, 7jt3:8, 7jt3:9, 4v95:AY, 6yst:y, 6ysu:y
14 7nql:BL 137 34 0.0456 0.1168 0.4706 0.10
15 1w5f:A 315 69 0.0598 0.0667 0.3043 0.59 1w5f:B
16 3hyu:A 141 48 0.0484 0.1206 0.3542 2.3 3a0g:A
17 7lm7:A 270 72 0.0598 0.0778 0.2917 5.1 3cx3:A, 3cx3:B, 7lm5:A, 7lm6:A
18 7obr:x 488 58 0.0484 0.0348 0.2931 6.4 2go5:W, 2j37:W, 5l3q:A, 5l3q:C, 1mfq:C, 7nfx:x, 7qwq:x, 1ry1:W, 4ue5:D, 6y2z:A, 6y32:A, 6y32:C, 6y32:E, 6y32:G
19 7ok0:A 880 38 0.0399 0.0159 0.3684 6.5 7oq4:A, 7oqy:A
20 6dcr:B 600 73 0.0684 0.0400 0.3288 8.1
21 5uf1:B 241 34 0.0342 0.0498 0.3529 9.7 5uf1:A, 5uf4:A, 5uf4:B, 5uf4:C
22 1mu0:A 293 43 0.0484 0.0580 0.3953 9.9 1xqw:A, 1xqx:A, 1xqy:A, 1xrl:A, 1xrm:A, 1xrn:A, 1xro:A, 1xrp:A, 1xrq:A, 1xrr:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218