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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
LAPNRFFFMSPYRSFTTSGCFARFDEPAVNGDSPDSPFQQKLAALFADAKAQGIKNPVMVGAIPFDPRQPSSLYIPESWQ
SFSRQEKQASQSLNVVERQAIPEQTTFEQMVARAAALTATPQVDKVVLSRLIDITTDAAIDSGVLLERLIAQNPVSYNFH
VPLADGGVLLGASPELLLRKDGEFSSIPLAGSARRQPDEVLDREAGNRLLASEKDRHEHELVTQAMKEVLRERSSELHVP
SSPQLITTPTLWHLATPFEGKANSQENALTLACLLHPTPALSGFPHQAATQVIAELEPFDRELFGGIVGWCDSEGNGEWV
VTIRCAKLRENQVRLFAGAGIVPASSPLGEWRETGVKLSTMLNVFGL

The query sequence (length=367) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 3hwo:A 379 375 1.0000 0.9683 0.9787 0.0 3hwo:B, 5jxz:A, 5jxz:B, 5jy4:A, 5jy4:B, 5jy8:A, 5jy8:B, 5jzd:A, 5jzd:B
2 3bzn:A 430 276 0.2398 0.2047 0.3188 1.89e-32
3 7bvd:A 499 222 0.1935 0.1423 0.3198 7.98e-26
4 8w6v:A 494 277 0.2098 0.1559 0.2780 5.88e-24 8w6v:B, 8w71:A, 8w71:B
5 5cwa:A 505 300 0.2452 0.1782 0.3000 2.60e-22
6 7pi1:DDD 459 258 0.1798 0.1438 0.2558 9.24e-17 7pi1:AAA, 7pi1:BBB, 7pi1:CCC, 7qu9:A, 7qu9:B, 7qu9:C
7 5jy9:B 424 266 0.2016 0.1745 0.2782 3.04e-12 2fn0:A, 2fn0:B, 2fn1:A, 2fn1:B, 5jy9:A
8 1i1q:A 512 227 0.1826 0.1309 0.2952 1.04e-11
9 3veh:B 451 265 0.2098 0.1707 0.2906 1.16e-11 2g5f:A, 2g5f:B, 3log:B, 8qc4:A, 8qc4:B, 8qn5:A, 8qn5:B, 8qn5:C, 8qn5:D, 3rv6:A, 3rv7:A, 3rv7:B, 3rv7:C, 3rv7:D, 3rv8:A, 3rv8:B, 3rv8:C, 3rv8:D, 3rv9:A, 3rv9:B, 3rv9:D, 3st6:A, 3st6:B, 3veh:A, 3veh:C, 3veh:D, 6za4:A, 6za4:C, 6za4:D, 6za5:B, 6za5:D
10 8hx9:A 632 225 0.1580 0.0918 0.2578 7.82e-11
11 8hx8:A 673 225 0.1580 0.0862 0.2578 7.92e-11 8hx6:A, 8hx6:B, 8hx7:A, 8hx7:B, 8hx8:B, 8hx9:B
12 1k0e:A 437 200 0.1444 0.1213 0.2650 5.19e-10 1k0g:A
13 1i7q:A 517 227 0.1717 0.1219 0.2775 1.75e-09 1i7q:C, 1i7s:A, 1i7s:C
14 6za4:B 423 259 0.1962 0.1702 0.2780 3.45e-07 3rv6:B, 3rv9:C
15 1k0g:B 415 87 0.0790 0.0699 0.3333 1.80e-06 1k0e:B
16 3r75:B 622 227 0.1471 0.0868 0.2379 1.14e-05 3r75:A, 3r76:A, 3r76:B
17 6dhd:A 501 115 0.1008 0.0739 0.3217 0.43 8ar7:A, 8ar7:B, 8ar7:C, 8ar7:E, 8ar7:D, 8ar7:F, 8ar8:A, 8ar8:B, 8ar8:C, 8ar8:D, 8ar8:E, 8ar8:F, 6dhd:B, 6dhd:C, 6dhd:D, 6dhd:F, 6dhd:E, 6dhk:A, 6dhk:B, 6dhk:F, 6dhk:C, 6dhk:D, 6dhk:E, 6dhk:G, 6dhk:H, 6dhk:L, 6dhk:I, 6dhk:J, 6dhk:K, 6dhl:A, 6dhl:F, 6dhl:B, 6dhl:C, 6dhl:D, 6dhl:E, 6dhl:G, 6dhl:L, 6dhl:H, 6dhl:I, 6dhl:J, 6dhl:K, 6dhm:A, 6dhm:B, 6dhm:C, 6dhm:D, 6dhm:E, 6dhm:F, 6dhn:A, 6dhn:B, 6dhn:C, 6dhn:D, 6dhn:E, 6dhn:F, 6dhq:A, 6dhq:B, 6dhq:C, 6dhq:D, 6dhq:E, 6dhq:F, 3etd:A, 3etd:E, 3etd:B, 3etd:C, 3etd:D, 3etd:F, 3ete:A, 3ete:E, 3ete:B, 3ete:C, 3ete:F, 3ete:D, 3etg:A, 3etg:B, 3etg:C, 3etg:D, 3etg:E, 3etg:F, 1hwy:A, 1hwy:B, 1hwy:F, 1hwy:C, 1hwy:E, 1hwy:D, 3jd0:A, 3jd0:B, 3jd0:C, 3jd0:D, 3jd0:E, 3jd0:F, 3jd1:A, 3jd1:C, 3jd1:B, 3jd1:D, 3jd1:F, 3jd1:E, 3jd2:A, 3jd2:B, 3jd2:C, 3jd2:D, 3jd2:E, 3jd2:F, 3jd3:A, 3jd3:B, 3jd3:C, 3jd3:D, 3jd3:E, 3jd3:F, 3jd4:A, 3jd4:C, 3jd4:B, 3jd4:D, 3jd4:F, 3jd4:E, 1nqt:A, 1nqt:B, 1nqt:F, 1nqt:C, 1nqt:D, 1nqt:E, 1nqt:G, 1nqt:H, 1nqt:L, 1nqt:I, 1nqt:J, 1nqt:K
18 4rap:E 390 28 0.0272 0.0256 0.3571 1.1 4rap:A, 4rap:D, 4rap:G, 4rap:K, 4rb4:K, 4rb4:L, 4rb4:C, 4rb4:D, 4rb4:E, 4rb4:H, 4rb4:B, 4rb4:F, 4rb4:G, 4rb4:I, 4rb4:J, 4rb4:A
19 7dcp:x 670 87 0.0681 0.0373 0.2874 2.7 7dco:x, 7dd3:x
20 7m7f:A 1390 35 0.0381 0.0101 0.4000 4.4 2fr0:A, 2fr1:A, 7m7i:A
21 7d3e:B 272 29 0.0327 0.0441 0.4138 6.9 7d3e:D, 7d3f:B, 7d3f:D
22 6wxu:B 273 29 0.0327 0.0440 0.4138 7.2 6wxr:B, 6wxu:D, 6wxv:B
23 4a62:A 320 42 0.0381 0.0437 0.3333 7.3 4a61:A, 4a62:B, 4a6j:A, 4a6j:B, 4a6j:C, 4a6j:D, 4a6j:E, 4a6j:F, 4a6j:G, 4a6j:H, 4a6j:I, 4a6j:J, 5aey:A, 5aey:B, 5aey:C, 5aey:D, 5aey:E, 1mwm:A, 1mwm:B, 2zgy:A, 2zgy:B, 2zgz:A, 2zgz:B, 2zhc:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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